iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNA	RAID2
Post-translational Modifications (PTMs)
dbPAF	PHOSIDA
Protein Expression/Proteomics

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 adaptor/Cullin RING/DCX/DWD	WD_repeat	18794348; 19111656

Classification

Family	E-value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.30e-21	74.8	137	170

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sd.tllvsGsdDgtikvWDlr 31
           gH++sv++++f  +d + +v+G++D ++k+WD+r
   Q: 137  GHEGSVRSICFapDDpNVFVTGGRDFQVKIWDMR 170
           8***********65599***************87 PP

Organism

Caenorhabditis elegans

Protein Sequence
(Fasta)

MDFLHSTKAR KRYLRYPSSI YEELESKHYS MPAGETDDHD TWVTARFSPH LNQEHILYMG 60
DDPGNIGIFD VRKFQDRSVP LEERQLYFFP AHDGAIMDVV GVPQKESQIV SISGDSTIRC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTAAGATCCG CGAAAAATGT GAATTCGAAA GGTTTCTTTT TTCTACCATT TTATAGTATT 60
TTCTACCATT TTATCATTTT CTCAACTAAA TTTCACTTTT TTCAGATAAA ATATGGATTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process

KEGG

cel:CELE_T01C3.1

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002111	Ailuropoda melanoleuca	27.60	3.00e-33	135.00
IUUC-Atr-003097	Amborella trichopoda	27.70	2.00e-32	132.00
IUUC-Apl-004088	Anas platyrhynchos	30.54	3.00e-36	145.00
IUUC-Aca-004732	Anolis carolinensis	27.98	5.00e-37	147.00
IUUC-Aly-005686	Arabidopsis lyrata	26.03	6.00e-34	137.00
IUUC-Ath-006970	Arabidopsis thaliana	27.02	2.00e-31	129.00
IUUC-Acl-008219	Aspergillus clavatus	22.41	3.00e-18	85.50
IUUC-Afu-008784	Aspergillus fumigatus	23.79	2.00e-16	79.70
IUUC-Ani-009304	Aspergillus nidulans	22.07	1.00e-13	70.50
IUUC-Ang-009842	Aspergillus niger	22.85	1.00e-19	90.10
IUUC-Aor-009883	Aspergillus oryzae	24.31	7.00e-18	84.70
IUUC-Ate-010454	Aspergillus terreus	28.21	2.00e-19	89.00
IUUC-Ame-010949	Astyanax mexicanus	30.08	9.00e-37	147.00
IUUC-Bta-012333	Bos taurus	27.32	4.00e-33	135.00
IUUC-Bci-013733	Botrytis cinerea	21.84	1.00e-15	77.40
IUUC-Bdi-014494	Brachypodium distachyon	28.27	5.00e-33	134.00
IUUC-Bol-015301	Brassica oleracea	26.76	5.00e-35	140.00
IUUC-Bra-017384	Brassica rapa	27.10	2.00e-35	142.00
IUUC-Cja-019534	Callithrix jacchus	27.90	6.00e-31	127.00
IUUC-Cfa-020847	Canis familiaris	27.60	7.00e-33	134.00
IUUC-Cpo-021695	Cavia porcellus	27.32	5.00e-32	131.00
IUUC-Cre-022762	Chlamydomonas reinhardtii	23.68	4.00e-21	97.10
IUUC-Csa-023748	Chlorocebus sabaeus	27.60	1.00e-32	133.00
IUUC-Cho-024445	Choloepus hoffmanni	29.70	5.00e-24	105.00
IUUC-Cgl-026664	Colletotrichum gloeosporioides	23.59	5.00e-14	71.60
IUUC-Dre-027536	Danio rerio	28.78	1.00e-36	146.00
IUUC-Dno-030035	Dasypus novemcinctus	27.60	3.00e-31	129.00
IUUC-Dse-031354	Dothistroma septosporum	21.36	6.00e-17	81.30
IUUC-Dme-031691	Drosophila melanogaster	29.19	1.00e-34	140.00
IUUC-Ete-032814	Echinops telfairi	26.68	8.00e-20	90.90
IUUC-Eca-033332	Equus caballus	27.32	1.00e-32	133.00
IUUC-Fca-035571	Felis catus	27.60	2.00e-33	136.00
IUUC-Fal-037421	Ficedula albicollis	29.81	3.00e-36	145.00
IUUC-Fox-038069	Fusarium oxysporum	23.24	7.00e-21	94.40
IUUC-Fso-038192	Fusarium solani	22.41	8.00e-16	77.80
IUUC-Gmo-039365	Gadus morhua	28.41	5.00e-33	134.00
IUUC-Ggr-039904	Gaeumannomyces graminis	23.57	1.00e-18	87.40
IUUC-Gga-041153	Gallus gallus	29.27	4.00e-34	138.00
IUUC-Gac-041984	Gasterosteus aculeatus	28.03	8.00e-31	127.00
IUUC-Gma-043734	Glycine max	29.90	3.00e-30	125.00
IUUC-Ggo-044419	Gorilla gorilla	27.52	2.00e-31	129.00
IUUC-Hsa-045862	Homo sapiens	27.60	1.00e-32	133.00
IUUC-Hvu-047728	Hordeum vulgare	28.99	2.00e-32	132.00
IUUC-Itr-048786	Ictidomys tridecemlineatus	27.60	7.00e-33	134.00
IUUC-Lch-050616	Latimeria chalumnae	28.42	1.00e-32	133.00
IUUC-Lpe-051222	Leersia perrieri	30.47	2.00e-35	142.00
IUUC-Loc-052564	Lepisosteus oculatus	29.86	1.00e-31	130.00
IUUC-Lma-053098	Leptosphaeria maculans	21.63	3.00e-18	85.90
IUUC-Laf-053892	Loxodonta africana	27.42	1.00e-32	134.00
IUUC-Mcc-055854	Macaca mulatta	27.60	1.00e-32	133.00
IUUC-Mor-057144	Magnaporthe oryzae	23.29	1.00e-15	77.40
IUUC-Mpo-057501	Magnaporthe poae	25.07	2.00e-14	73.20
IUUC-Mtr-058510	Medicago truncatula	26.34	9.00e-28	116.00
IUUC-Mla-058823	Melampsora laricipopulina	23.53	2.00e-14	72.80
IUUC-Mga-060128	Meleagris gallopavo	29.00	2.00e-33	135.00
IUUC-Mvi-060475	Microbotryum violaceum	27.96	7.00e-30	124.00
IUUC-Mmr-061331	Microcebus murinus	27.32	3.00e-32	132.00
IUUC-Mdo-063020	Monodelphis domestica	27.70	1.00e-32	133.00
IUUC-Mmu-063713	Mus musculus	27.32	3.00e-31	129.00
IUUC-Mac-064653	Musa acuminata	27.93	6.00e-32	130.00
IUUC-Mpu-066490	Mustela putorius furo	27.60	3.00e-33	135.00
IUUC-Mlu-067900	Myotis lucifugus	27.05	1.00e-31	130.00
IUUC-Nfi-068433	Neosartorya fischeri	24.25	2.00e-17	83.60
IUUC-Ncr-068776	Neurospora crassa	22.49	5.00e-12	65.10
IUUC-Nle-069675	Nomascus leucogenys	29.08	3.00e-32	132.00
IUUC-Ont-071441	Oreochromis niloticus	27.35	5.00e-35	141.00
IUUC-Oan-072757	Ornithorhynchus anatinus	26.04	5.00e-32	131.00
IUUC-Ocu-074670	Oryctolagus cuniculus	28.69	6.00e-34	137.00
IUUC-Oba-075844	Oryza barthii	29.64	7.00e-36	144.00
IUUC-Obr-076625	Oryza brachyantha	30.87	6.00e-38	150.00
IUUC-Ogl-077771	Oryza glaberrima	29.64	8.00e-36	143.00
IUUC-Ogu-078475	Oryza glumaepatula	28.06	7.00e-27	114.00
IUUC-Oin-079958	Oryza indica	29.64	9.00e-36	143.00
IUUC-Olo-080311	Oryza longistaminata	30.03	3.00e-31	128.00
IUUC-Ome-081985	Oryza meridionalis	30.11	2.00e-35	142.00
IUUC-Oni-082921	Oryza nivara	29.64	9.00e-36	143.00
IUUC-Opu-083174	Oryza punctata	28.20	1.00e-32	132.00
IUUC-Oru-084338	Oryza rufipogon	29.64	7.00e-36	144.00
IUUC-Olu-087907	Ostreococcus lucimarinus	25.25	1.00e-14	72.80
IUUC-Oga-088358	Otolemur garnettii	28.14	2.00e-33	136.00
IUUC-Oar-089994	Ovis aries	27.32	6.00e-33	134.00
IUUC-Ptr-091338	Pan troglodytes	27.60	1.00e-32	134.00
IUUC-Pan-091759	Papio anubis	27.52	3.00e-31	129.00
IUUC-Psi-093211	Pelodiscus sinensis	27.75	1.00e-31	130.00
IUUC-Pma-094588	Petromyzon marinus	31.09	5.00e-21	93.60
IUUC-Pno-094964	Phaeosphaeria nodorum	23.96	2.00e-21	96.30
IUUC-Ppa-095159	Physcomitrella patens	29.41	2.00e-37	148.00
IUUC-Pfo-096592	Poecilia formosa	25.55	9.00e-27	114.00
IUUC-Pab-098597	Pongo abelii	28.65	4.00e-15	75.50
IUUC-Pop-099255	Populus trichocarpa	28.45	7.00e-33	133.00
IUUC-Pca-100593	Procavia capensis	31.96	3.00e-20	92.40
IUUC-Ppe-101333	Prunus persica	27.71	3.00e-34	138.00
IUUC-Pva-102283	Pteropus vampyrus	27.95	1.00e-28	120.00
IUUC-Pgr-103383	Puccinia graminis	24.64	1.00e-10	60.50
IUUC-Ptt-103974	Puccinia triticina	25.56	6.00e-10	57.80
IUUC-Pte-104329	Pyrenophora teres	24.30	2.00e-17	82.80
IUUC-Pyt-104424	Pyrenophora triticirepentis	23.68	2.00e-16	79.70
IUUC-Rno-105720	Rattus norvegicus	27.60	7.00e-32	131.00
IUUC-Sha-106891	Sarcophilus harrisii	26.90	1.00e-25	110.00
IUUC-Sja-107723	Schizosaccharomyces japonicus	22.14	4.00e-18	84.70
IUUC-Spo-108060	Schizosaccharomyces pombe	26.78	1.00e-22	99.80
IUUC-Ssl-108481	Sclerotinia sclerotiorum	23.09	1.00e-15	77.00
IUUC-Sit-109862	Setaria italica	29.55	7.00e-38	150.00
IUUC-Sly-111468	Solanum lycopersicum	30.47	7.00e-32	130.00
IUUC-Stu-112346	Solanum tuberosum	29.78	2.00e-32	132.00
IUUC-Sar-113734	Sorex araneus	31.08	6.00e-12	64.70
IUUC-Sbi-114076	Sorghum bicolor	29.79	1.00e-36	146.00
IUUC-Sre-114918	Sporisorium reilianum	23.99	6.00e-12	65.10
IUUC-Ssc-115561	Sus scrofa	26.98	6.00e-31	127.00
IUUC-Tgu-117011	Taeniopygia guttata	28.53	2.00e-35	142.00
IUUC-Tru-118411	Takifugu rubripes	29.25	2.00e-32	132.00
IUUC-Tsy-119367	Tarsius syrichta	24.53	1.00e-16	80.10
IUUC-Tni-120301	Tetraodon nigroviridis	27.35	4.00e-34	138.00
IUUC-Tca-121265	Theobroma cacao	27.51	6.00e-34	137.00
IUUC-Tre-121997	Trichoderma reesei	23.97	7.00e-19	87.80
IUUC-Tvi-122292	Trichoderma virens	23.54	9.00e-22	97.40
IUUC-Tae-123660	Triticum aestivum	30.05	6.00e-37	147.00
IUUC-Tur-126794	Triticum urartu	29.26	1.00e-31	129.00
IUUC-Tme-127090	Tuber melanosporum	21.02	2.00e-12	65.10
IUUC-Tbe-127646	Tupaia belangeri	25.14	2.00e-22	99.40
IUUC-Ttr-128171	Tursiops truncatus	27.32	1.00e-32	133.00
IUUC-Uma-129525	Ustilago maydis	22.49	6.00e-11	61.60
IUUC-Vda-129871	Verticillium dahliae	23.64	2.00e-16	80.10
IUUC-Vpa-130554	Vicugna pacos	30.95	1.00e-13	70.50
IUUC-Vvi-131698	Vitis vinifera	30.83	2.00e-36	145.00
IUUC-Xtr-131962	Xenopus tropicalis	27.90	4.00e-37	148.00
IUUC-Xma-133803	Xiphophorus maculatus	27.35	1.00e-33	136.00
IUUC-Zma-135932	Zea mays	28.89	2.00e-34	139.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence