iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSG00000099999.14	ENST00000421022.1	ENSP00000396278.1
ENSG00000099999.14	ENST00000382363.7	ENSP00000371800.3
ENSG00000099999.14	ENST00000215798.10	ENSP00000215798.6
ENSG00000099999.14	ENST00000619645.1	ENSP00000486180.1

Annotation

Cancer Mutation
TCGA	ICGC	COSMIC	CGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	TCGA	ICGC
COSMIC	THPA
DNA & RNA Element
UTRdb	AREsite	CircNet	miRTarBase
microRNA	TRANSFAC	TargetScan	RepTar
miRcode	RAID2
Post-translational Modifications (PTMs)
CPLM	dbPAF	PhosphositePlus	dbPTM
DNA Methylation
TCGA	ICGC	COSMIC
Protein Expression/Proteomics
THPA	GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.70e-07	32.2	325	366

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdg..plvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+Cl+ f++   ++vlpC+H fh+dC+  w       + +++CPlC+
   Q: 325  CAVCLDYFCNKqwLRVLPCKHEFHRDCVDPW------LMLQQTCPLCK 366
           ********5555699****************......**********7 PP

Organism

Homo sapiens

Protein Sequence
(Fasta)

MGPAARPALR SPPPPPPPPP SPLLLLLPLL PLWLGLAGPG AAADGSEPAA GAGRGGARAV 60
RVDVRLPRQD ALVLEGVRIG SEADPAPLLG GRLLLMDIVD AEQEAPVEGW IAVAYVGKEQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACACAGTGAG GAAATGACAG AGCTGGAGTT TCCGTCTGTT CCACATTGCT GCATTTGTTC 60
TGCCTGACTT GGACCCTGGA AAACCTGGCC CTCTTCAATT TCTGACAAAA GGTAAAATGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0325--Glycoprotein
KW-0472--Membrane
KW-0479--Metal-binding
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0008270--F:zinc ion binding

KEGG

hsa:200312

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001857	Ailuropoda melanoleuca	93.49	9.00e-143	499.00
IUUC-Aca-005033	Anolis carolinensis	51.66	6.00e-53	201.00
IUUC-Afu-009008	Aspergillus fumigatus	43.08	2.00e-12	67.40
IUUC-Ang-009613	Aspergillus niger	47.46	5.00e-12	66.20
IUUC-Ate-010341	Aspergillus terreus	45.16	1.00e-12	68.20
IUUC-Ame-011435	Astyanax mexicanus	45.19	9.00e-56	210.00
IUUC-Bta-013568	Bos taurus	90.16	1.00e-135	475.00
IUUC-Bdi-014927	Brachypodium distachyon	42.65	1.00e-12	67.00
IUUC-Bol-015464	Brassica oleracea	49.18	3.00e-13	69.70
IUUC-Bra-017274	Brassica rapa	49.18	3.00e-13	69.70
IUUC-Cja-019973	Callithrix jacchus	96.75	6.00e-164	570.00
IUUC-Cfa-020557	Canis familiaris	94.61	5.00e-148	518.00
IUUC-Cpo-022520	Cavia porcellus	93.99	2.00e-154	538.00
IUUC-Csa-024093	Chlorocebus sabaeus	98.94	3.00e-148	517.00
IUUC-Cho-024467	Choloepus hoffmanni	65.71	3.00e-71	260.00
IUUC-Cin-025111	Ciona intestinalis	35.02	1.00e-35	142.00
IUUC-Csv-026123	Ciona savignyi	36.65	4.00e-23	100.00
IUUC-Cme-027166	Cyanidioschyzon merolae	43.75	2.00e-13	68.60
IUUC-Dre-028405	Danio rerio	45.61	6.00e-65	241.00
IUUC-Dno-029070	Dasypus novemcinctus	91.46	3.00e-142	498.00
IUUC-Dor-030676	Dipodomys ordii	70.48	3.00e-104	371.00
IUUC-Eca-034184	Equus caballus	94.46	1.00e-143	501.00
IUUC-Fca-036391	Felis catus	96.11	1.00e-160	558.00
IUUC-Fal-036961	Ficedula albicollis	55.68	1.00e-59	223.00
IUUC-Gmo-038637	Gadus morhua	46.42	5.00e-63	234.00
IUUC-Gga-040442	Gallus gallus	55.36	7.00e-65	241.00
IUUC-Ggo-045499	Gorilla gorilla	100.00	2.00e-168	584.00
IUUC-Itr-048527	Ictidomys tridecemlineatus	92.81	9.00e-154	536.00
IUUC-Lch-050604	Latimeria chalumnae	47.47	2.00e-63	236.00
IUUC-Loc-052044	Lepisosteus oculatus	49.08	6.00e-66	244.00
IUUC-Laf-053996	Loxodonta africana	89.97	2.00e-154	538.00
IUUC-Mcc-055068	Macaca mulatta	99.04	4.00e-165	573.00
IUUC-Meu-056824	Macropus eugenii	59.21	1.00e-67	249.00
IUUC-Mga-059696	Meleagris gallopavo	60.26	1.00e-59	222.00
IUUC-Mmr-061408	Microcebus murinus	94.92	2.00e-157	548.00
IUUC-Mmu-063515	Mus musculus	90.86	2.00e-150	525.00
IUUC-Mpu-066071	Mustela putorius furo	94.01	2.00e-150	525.00
IUUC-Mlu-067153	Myotis lucifugus	75.08	4.00e-104	370.00
IUUC-Nfi-068450	Neosartorya fischeri	42.42	2.00e-12	67.40
IUUC-Nle-069074	Nomascus leucogenys	99.36	2.00e-165	575.00
IUUC-Ont-072099	Oreochromis niloticus	52.72	2.00e-58	218.00
IUUC-Ocu-074883	Oryctolagus cuniculus	94.15	2.00e-103	368.00
IUUC-Obr-076360	Oryza brachyantha	49.06	7.00e-12	64.30
IUUC-Oga-088701	Otolemur garnettii	91.35	2.00e-150	525.00
IUUC-Oar-090127	Ovis aries	87.22	9.00e-142	496.00
IUUC-Ptr-091529	Pan troglodytes	93.91	2.00e-153	535.00
IUUC-Pan-092211	Papio anubis	98.94	3.00e-148	517.00
IUUC-Pfo-096113	Poecilia formosa	47.96	2.00e-61	229.00
IUUC-Pab-097593	Pongo abelii	98.40	3.00e-164	570.00
IUUC-Pop-099388	Populus trichocarpa	48.15	2.00e-12	67.00
IUUC-Pca-100666	Procavia capensis	92.47	8.00e-87	313.00
IUUC-Ppe-101311	Prunus persica	45.45	9.00e-13	67.40
IUUC-Rno-105272	Rattus norvegicus	92.04	1.00e-158	552.00
IUUC-Sha-107618	Sarcophilus harrisii	57.61	7.00e-72	263.00
IUUC-Smo-108796	Selaginella moellendorffii	34.95	1.00e-12	67.00
IUUC-Ssc-115909	Sus scrofa	91.32	7.00e-155	540.00
IUUC-Tni-119836	Tetraodon nigroviridis	42.58	4.00e-58	218.00
IUUC-Tca-121397	Theobroma cacao	52.17	8.00e-12	64.30
IUUC-Tbe-127706	Tupaia belangeri	93.66	5.00e-138	483.00
IUUC-Ttr-128577	Tursiops truncatus	93.27	1.00e-104	372.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence