iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cin-025419

UUCD1 version

UUC-CiI-00547

Ensembl Protein ID

ENSCINP00000034116.1

UniProt Accession

H2XWT2; H2XWT2_CIOIN

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCING00000018639.1	ENSCINT00000031450.1	ENSCINP00000034116.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.20e-42	144.7	6	143

Active Site

Position(s)	Description	Evidence
86	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk.. 87
           Rlk+el+ l+++p++gis+ ++++ +++ ++++i+G ++tpY+gg+F++e+++p++YPf+PPk +f+t+i+hPn+++ G++Cl+ lk  
   Q: 6    RLKRELHMLAQNPSPGISCWQDEN-QINVIHAQIIGSDGTPYAGGIFSIEVSVPDRYPFEPPKARFMTPIYHPNIDSGGRICLDTLKmp 93
           99*******************999.7************************************************************988 PP
   S: 88   eeekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkv 137
           ++ +W+p l++ s+l++iq l++epnp++pl ++++ ++k ++ ++ +k+
   Q: 94   PQGAWKPSLNIGSILTTIQLLMSEPNPDDPLMADISAEYKFDKPMFTQKA 143
           999*******************************************9986 PP

Organism

Ciona intestinalis

Protein Sequence
(Fasta)

MQRSLRLKRE LHMLAQNPSP GISCWQDENQ INVIHAQIIG SDGTPYAGGI FSIEVSVPDR 60
YPFEPPKARF MTPIYHPNID SGGRICLDTL KMPPQGAWKP SLNIGSILTT IQLLMSEPNP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTAAGTATAT TCGAATTTAA AATGCAAAGA AGTTTACGAT TAAAACGCGA GTTACATATG 60
TTGGCTCAAA ATCCTTCACC GGGAATATCT TGCTGGCAAG ATGAAAACCA AATAAATGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0006974--P:cellular response to DNA damage stimulus
GO:0000209--P:protein polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000366	Aegilops tauschii	47.71	5.00e-39	154.00
IUUC-Aml-001392	Ailuropoda melanoleuca	64.29	6.00e-63	231.00
IUUC-Atr-003069	Amborella trichopoda	52.98	1.00e-46	178.00
IUUC-Apl-003914	Anas platyrhynchos	64.24	1.00e-59	220.00
IUUC-Aca-004381	Anolis carolinensis	64.90	8.00e-61	225.00
IUUC-Aly-006059	Arabidopsis lyrata	49.68	7.00e-43	166.00
IUUC-Ath-007669	Arabidopsis thaliana	56.52	3.00e-39	154.00
IUUC-Ame-011372	Astyanax mexicanus	61.69	8.00e-58	214.00
IUUC-Bta-012479	Bos taurus	62.99	1.00e-59	220.00
IUUC-Bdi-014043	Brachypodium distachyon	49.67	5.00e-43	167.00
IUUC-Bol-016011	Brassica oleracea	47.47	1.00e-40	159.00
IUUC-Bra-017419	Brassica rapa	47.47	4.00e-40	157.00
IUUC-Cja-019773	Callithrix jacchus	66.23	4.00e-64	236.00
IUUC-Cfa-020043	Canis familiaris	64.94	9.00e-63	231.00
IUUC-Cpo-021481	Cavia porcellus	63.64	7.00e-62	228.00
IUUC-Cre-022823	Chlamydomonas reinhardtii	46.26	8.00e-30	121.00
IUUC-Csa-024083	Chlorocebus sabaeus	66.23	1.00e-63	233.00
IUUC-Cho-024386	Choloepus hoffmanni	65.58	3.00e-62	229.00
IUUC-Csv-026224	Ciona savignyi	88.31	1.00e-80	291.00
IUUC-Cme-027179	Cyanidioschyzon merolae	49.33	2.00e-38	150.00
IUUC-Dre-028800	Danio rerio	62.34	2.00e-62	230.00
IUUC-Dno-029833	Dasypus novemcinctus	66.23	4.00e-62	229.00
IUUC-Ete-032625	Echinops telfairi	64.90	3.00e-55	205.00
IUUC-Eca-033821	Equus caballus	65.58	2.00e-62	229.00
IUUC-Eeu-034578	Erinaceus europaeus	71.28	9.00e-40	154.00
IUUC-Fca-036398	Felis catus	64.94	2.00e-62	230.00
IUUC-Fal-037564	Ficedula albicollis	64.90	2.00e-58	216.00
IUUC-Gmo-039142	Gadus morhua	64.94	2.00e-62	229.00
IUUC-Gga-041054	Gallus gallus	65.56	2.00e-59	220.00
IUUC-Gac-041370	Gasterosteus aculeatus	64.29	2.00e-62	229.00
IUUC-Ggo-045370	Gorilla gorilla	66.23	4.00e-63	232.00
IUUC-Hsa-046513	Homo sapiens	66.23	2.00e-63	233.00
IUUC-Hvu-047694	Hordeum vulgare	49.67	5.00e-43	167.00
IUUC-Itr-049076	Ictidomys tridecemlineatus	65.56	2.00e-62	230.00
IUUC-Lch-050484	Latimeria chalumnae	62.04	7.00e-53	198.00
IUUC-Loc-051967	Lepisosteus oculatus	64.29	3.00e-62	229.00
IUUC-Laf-053377	Loxodonta africana	66.23	2.00e-63	233.00
IUUC-Mcc-055453	Macaca mulatta	66.23	1.00e-63	233.00
IUUC-Meu-056745	Macropus eugenii	67.55	2.00e-63	233.00
IUUC-Mga-059729	Meleagris gallopavo	66.23	4.00e-60	222.00
IUUC-Mmr-060581	Microcebus murinus	66.88	2.00e-64	236.00
IUUC-Mdo-062434	Monodelphis domestica	67.55	1.00e-62	232.00
IUUC-Mmu-064379	Mus musculus	64.29	3.00e-61	226.00
IUUC-Mac-064647	Musa acuminata	58.47	2.00e-41	160.00
IUUC-Mpu-066713	Mustela putorius furo	63.64	8.00e-62	228.00
IUUC-Mlu-067525	Myotis lucifugus	64.90	4.00e-61	225.00
IUUC-Nle-069757	Nomascus leucogenys	66.23	1.00e-63	234.00
IUUC-Opr-070756	Ochotona princeps	64.94	3.00e-62	229.00
IUUC-Ont-071956	Oreochromis niloticus	66.88	7.00e-64	234.00
IUUC-Oan-072745	Ornithorhynchus anatinus	62.99	2.00e-59	219.00
IUUC-Ocu-074423	Oryctolagus cuniculus	65.56	8.00e-62	228.00
IUUC-Oba-075569	Oryza barthii	49.02	2.00e-41	162.00
IUUC-Obr-076131	Oryza brachyantha	49.67	1.00e-41	162.00
IUUC-Ogl-077132	Oryza glaberrima	49.02	2.00e-41	162.00
IUUC-Ogu-078880	Oryza glumaepatula	49.02	2.00e-41	162.00
IUUC-Oin-079748	Oryza indica	49.02	2.00e-41	162.00
IUUC-Olo-080501	Oryza longistaminata	49.02	3.00e-42	164.00
IUUC-Ome-081248	Oryza meridionalis	49.02	2.00e-41	162.00
IUUC-Oni-083033	Oryza nivara	49.02	2.00e-41	162.00
IUUC-Opu-083664	Oryza punctata	49.02	1.00e-39	156.00
IUUC-Oru-084580	Oryza rufipogon	49.02	2.00e-41	162.00
IUUC-Osa-085721	Oryza sativa	49.02	2.00e-41	162.00
IUUC-Ola-087559	Oryzias latipes	65.58	6.00e-63	231.00
IUUC-Oga-088420	Otolemur garnettii	66.88	1.00e-63	234.00
IUUC-Oar-090082	Ovis aries	60.90	6.00e-58	215.00
IUUC-Ptr-091134	Pan troglodytes	66.23	2.00e-63	233.00
IUUC-Pan-091735	Papio anubis	66.23	1.00e-63	233.00
IUUC-Psi-094064	Pelodiscus sinensis	66.23	7.00e-62	228.00
IUUC-Pma-094609	Petromyzon marinus	62.91	8.00e-58	214.00
IUUC-Ppa-095553	Physcomitrella patens	58.78	3.00e-50	191.00
IUUC-Pfo-096710	Poecilia formosa	66.45	7.00e-63	231.00
IUUC-Pab-098126	Pongo abelii	66.23	2.00e-63	233.00
IUUC-Pop-099108	Populus trichocarpa	52.94	5.00e-46	177.00
IUUC-Pca-100338	Procavia capensis	66.23	2.00e-63	233.00
IUUC-Ppe-101239	Prunus persica	58.68	2.00e-42	165.00
IUUC-Pva-102756	Pteropus vampyrus	67.68	4.00e-41	158.00
IUUC-Rno-105211	Rattus norvegicus	64.29	8.00e-61	224.00
IUUC-Sha-106969	Sarcophilus harrisii	62.58	2.00e-54	203.00
IUUC-Smo-109052	Selaginella moellendorffii	53.33	5.00e-42	162.00
IUUC-Sit-110464	Setaria italica	51.01	8.00e-42	163.00
IUUC-Sly-110971	Solanum lycopersicum	52.98	5.00e-44	171.00
IUUC-Stu-112126	Solanum tuberosum	54.00	2.00e-44	172.00
IUUC-Sar-113633	Sorex araneus	66.23	2.00e-62	229.00
IUUC-Sbi-114875	Sorghum bicolor	51.63	7.00e-44	170.00
IUUC-Ssc-116375	Sus scrofa	64.00	3.00e-60	223.00
IUUC-Tgu-117292	Taeniopygia guttata	62.91	1.00e-56	210.00
IUUC-Tru-118157	Takifugu rubripes	54.55	3.00e-50	189.00
IUUC-Tsy-119260	Tarsius syrichta	66.23	6.00e-63	231.00
IUUC-Tni-120162	Tetraodon nigroviridis	65.58	4.00e-62	229.00
IUUC-Tca-121255	Theobroma cacao	51.32	7.00e-34	137.00
IUUC-Tae-125721	Triticum aestivum	47.71	6.00e-41	160.00
IUUC-Tbe-127296	Tupaia belangeri	65.58	1.00e-62	230.00
IUUC-Ttr-128443	Tursiops truncatus	62.91	9.00e-60	221.00
IUUC-Vpa-130689	Vicugna pacos	64.24	1.00e-61	227.00
IUUC-Vvi-130925	Vitis vinifera	52.60	1.00e-43	167.00
IUUC-Xma-133779	Xiphophorus maculatus	67.11	5.00e-63	231.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence