iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ppa-095254

Ensembl Protein ID

PP1S86_189V6.2

UniProt Accession

A9SK16; A9SK16_PHYPA

Genbank Protein ID

EDQ68562.1

Protein Name

Coatomer subunit alpha

Genbank Nucleotide ID

DS544975

Gene Name

PHYPADRAFT_213150

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PP1S86_189V6	PP1S86_189V6.2	PP1S86_189V6.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.10e-34	116.8	91	127
UBD/Beta-Prp	2.30e-75	254.3	3	323

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gH d ++ ++f ++ + +vs+sdD ti++W++ + ++
   Q: 91   GHLDYIRTVKFhHEsPWIVSASDDQTIRIWNWQSRTC 127
           8**********96669***************987766 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvl 98
           t +++++++++ + f+  +++++++  +g i++wd+++g+l+ ++ +h+++v+ v+f+++++++v+g++D+ ikvw+++ + c+ tl gh d+++
   Q: 3    TKFETKSNRVKGLSFHSRRPWILASLHSGIIQLWDYRMGTLIDRFDEHDGPVRGVDFHKSQPLFVSGGDDYKIKVWNYKMRRCLFTLLGHLDYIR 97
           67889999*************************************************************************************** PP
   S: 99   slsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl..........................k 167
           +++f+ ++ ++vs+s+d+tir+w++++++c++ +l+gh++ v+c+++h +++l+vs+slD+tvr+Wd+                           
   Q: 98   TVKFHHESPWIVSASDDQTIRIWNWQSRTCIS-VLTGHNHYVMCASFHIKEDLVVSASLDQTVRVWDIgalkkksvspaddmmrlaqmntdlfgG 191
           ********************************.********************************************999999666666665553 PP
   S: 168  tgkllrtl.......tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrs 253
                           +gh++ v++ sf+++ + +vsg++d++vklw +  ++   v+tl+gh +nv++v f+ +++ +vs s+D+sir+Wd+ +
   Q: 192  -------GdsvvkyvLEGHDRGVNWASFHPSLPLIVSGADDRQVKLWRMNDTKAweVDTLRGHVNNVSCVLFHARQDVIVSNSEDKSIRVWDMSK 279
           .......04444445555********************************777668*************************************** PP
   S: 254  gdllktlqlhnssvisvavlsfgdnvlvlgsedskvniwklkknep 299
           ++ ++t+ +++++++  +v +++ n l++g  ds   ++kl++++p
   Q: 280  RTGVQTFRREHDRFWILSV-HPEMNLLAAG-HDSGMIVFKLERERP 323
           *******************.6666655555.689999999988765 PP

Organism

Physcomitrella patens

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MLTKFETKSN RVKGLSFHSR RPWILASLHS GIIQLWDYRM GTLIDRFDEH DGPVRGVDFH 60
KSQPLFVSGG DDYKIKVWNY KMRRCLFTLL GHLDYIRTVK FHHESPWIVS ASDDQTIRIW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTGACCA AGTTCGAGAC GAAGAGTAAC AGGGTGAAGG GGCTGAGCTT TCACTCGCGG 60
CGGCCATGGA TTCTCGCCAG CTTGCACAGC GGCATTATTC AGCTGTGGGA CTACCGGATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011048--Haem_d1
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006891--P:intra-Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER

KEGG

ppp:PHYPADRAFT_213150

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001758	Ailuropoda melanoleuca	56.55	0.00e+00	1422.00
IUUC-Atr-002493	Amborella trichopoda	71.12	0.00e+00	1785.00
IUUC-Apl-003385	Anas platyrhynchos	52.79	0.00e+00	1102.00
IUUC-Ath-007058	Arabidopsis thaliana	69.07	0.00e+00	1719.00
IUUC-Afl-008644	Aspergillus flavus	49.96	0.00e+00	1187.00
IUUC-Afu-008964	Aspergillus fumigatus	50.57	0.00e+00	1205.00
IUUC-Ani-009379	Aspergillus nidulans	58.67	0.00e+00	1047.00
IUUC-Ang-009756	Aspergillus niger	50.77	0.00e+00	1210.00
IUUC-Aor-010174	Aspergillus oryzae	49.96	0.00e+00	1186.00
IUUC-Ate-010302	Aspergillus terreus	51.38	0.00e+00	1238.00
IUUC-Ame-011229	Astyanax mexicanus	56.24	0.00e+00	1380.00
IUUC-Bgr-012300	Blumeria graminis	48.15	0.00e+00	1125.00
IUUC-Bta-012524	Bos taurus	57.04	0.00e+00	1414.00
IUUC-Bol-015925	Brassica oleracea	68.79	0.00e+00	1708.00
IUUC-Cel-018115	Caenorhabditis elegans	56.35	0.00e+00	958.00
IUUC-Cja-019107	Callithrix jacchus	56.04	0.00e+00	1399.00
IUUC-Cfa-020675	Canis familiaris	56.24	0.00e+00	1392.00
IUUC-Cpo-021813	Cavia porcellus	57.29	0.00e+00	1432.00
IUUC-Csa-023523	Chlorocebus sabaeus	57.18	0.00e+00	1433.00
IUUC-Cho-024704	Choloepus hoffmanni	44.43	0.00e+00	634.00
IUUC-Cin-025572	Ciona intestinalis	54.14	0.00e+00	1328.00
IUUC-Csv-025864	Ciona savignyi	62.23	0.00e+00	1048.00
IUUC-Cgl-026510	Colletotrichum gloeosporioides	59.59	0.00e+00	1041.00
IUUC-Cne-027053	Cryptococcus neoformans	59.11	0.00e+00	1046.00
IUUC-Cme-027222	Cyanidioschyzon merolae	40.00	6.00e-149	521.00
IUUC-Dno-029303	Dasypus novemcinctus	57.28	0.00e+00	1437.00
IUUC-Dme-031945	Drosophila melanogaster	63.14	0.00e+00	1075.00
IUUC-Ete-032873	Echinops telfairi	54.24	0.00e+00	1257.00
IUUC-Eca-033773	Equus caballus	56.42	0.00e+00	1397.00
IUUC-Eeu-034874	Erinaceus europaeus	44.72	0.00e+00	706.00
IUUC-Fca-035739	Felis catus	55.78	0.00e+00	1394.00
IUUC-Fal-037263	Ficedula albicollis	53.70	0.00e+00	1264.00
IUUC-Fso-038153	Fusarium solani	50.37	0.00e+00	1202.00
IUUC-Ggr-039931	Gaeumannomyces graminis	58.50	0.00e+00	1034.00
IUUC-Gga-040590	Gallus gallus	57.44	0.00e+00	1425.00
IUUC-Gac-041318	Gasterosteus aculeatus	55.10	0.00e+00	1397.00
IUUC-Gma-043257	Glycine max	68.65	0.00e+00	1764.00
IUUC-Ggo-045029	Gorilla gorilla	56.87	0.00e+00	1425.00
IUUC-Hsa-046078	Homo sapiens	56.77	0.00e+00	1424.00
IUUC-Itr-048881	Ictidomys tridecemlineatus	49.02	0.00e+00	822.00
IUUC-Lch-049706	Latimeria chalumnae	56.89	0.00e+00	1412.00
IUUC-Loc-051867	Lepisosteus oculatus	42.09	0.00e+00	898.00
IUUC-Laf-053510	Loxodonta africana	57.13	0.00e+00	1436.00
IUUC-Mcc-055836	Macaca mulatta	56.88	0.00e+00	1426.00
IUUC-Meu-056238	Macropus eugenii	59.68	0.00e+00	809.00
IUUC-Mor-057172	Magnaporthe oryzae	50.53	0.00e+00	1201.00
IUUC-Mpo-057300	Magnaporthe poae	49.51	0.00e+00	1186.00
IUUC-Mtr-058248	Medicago truncatula	69.92	0.00e+00	1766.00
IUUC-Mla-059019	Melampsora laricipopulina	51.98	0.00e+00	1281.00
IUUC-Mga-059499	Meleagris gallopavo	57.43	0.00e+00	1422.00
IUUC-Mvi-060336	Microbotryum violaceum	52.78	0.00e+00	1257.00
IUUC-Mmr-061102	Microcebus murinus	56.29	0.00e+00	1413.00
IUUC-Mdo-062594	Monodelphis domestica	57.17	0.00e+00	1442.00
IUUC-Mmu-063736	Mus musculus	56.88	0.00e+00	1426.00
IUUC-Mpu-066701	Mustela putorius furo	57.28	0.00e+00	1424.00
IUUC-Mlu-067392	Myotis lucifugus	56.76	0.00e+00	1417.00
IUUC-Nfi-068270	Neosartorya fischeri	59.74	0.00e+00	1045.00
IUUC-Ncr-068892	Neurospora crassa	49.84	0.00e+00	1176.00
IUUC-Nle-069634	Nomascus leucogenys	68.76	0.00e+00	980.00
IUUC-Opr-070952	Ochotona princeps	44.41	0.00e+00	707.00
IUUC-Ont-072488	Oreochromis niloticus	55.93	0.00e+00	1386.00
IUUC-Ocu-074211	Oryctolagus cuniculus	57.12	0.00e+00	1430.00
IUUC-Ola-086921	Oryzias latipes	55.23	0.00e+00	1375.00
IUUC-Olu-087639	Ostreococcus lucimarinus	64.88	0.00e+00	1637.00
IUUC-Oga-087991	Otolemur garnettii	53.64	0.00e+00	1320.00
IUUC-Oar-089590	Ovis aries	57.12	0.00e+00	1434.00
IUUC-Ptr-090808	Pan troglodytes	56.77	0.00e+00	1423.00
IUUC-Pan-092475	Papio anubis	57.07	0.00e+00	1425.00
IUUC-Psi-093044	Pelodiscus sinensis	50.46	0.00e+00	1031.00
IUUC-Pab-098497	Pongo abelii	57.10	0.00e+00	1433.00
IUUC-Pop-099992	Populus trichocarpa	71.58	0.00e+00	1768.00
IUUC-Pva-102126	Pteropus vampyrus	54.06	0.00e+00	1342.00
IUUC-Pgr-103376	Puccinia graminis	52.79	0.00e+00	1288.00
IUUC-Ptt-103978	Puccinia triticina	46.13	0.00e+00	1055.00
IUUC-Rno-105428	Rattus norvegicus	56.97	0.00e+00	1432.00
IUUC-Sha-107301	Sarcophilus harrisii	56.75	0.00e+00	1407.00
IUUC-Sja-107961	Schizosaccharomyces japonicus	46.84	0.00e+00	1131.00
IUUC-Spo-108217	Schizosaccharomyces pombe	47.05	0.00e+00	1121.00
IUUC-Sly-111759	Solanum lycopersicum	70.43	0.00e+00	1825.00
IUUC-Stu-112564	Solanum tuberosum	70.43	0.00e+00	1821.00
IUUC-Sar-113313	Sorex araneus	47.15	0.00e+00	657.00
IUUC-Ssc-115933	Sus scrofa	57.04	0.00e+00	1431.00
IUUC-Tru-117772	Takifugu rubripes	55.77	0.00e+00	1365.00
IUUC-Tni-120556	Tetraodon nigroviridis	43.91	0.00e+00	943.00
IUUC-Tvi-122359	Trichoderma virens	49.80	0.00e+00	1194.00
IUUC-Ttr-128217	Tursiops truncatus	54.94	0.00e+00	1361.00
IUUC-Vda-129828	Verticillium dahliae	49.63	0.00e+00	1163.00
IUUC-Vpa-130537	Vicugna pacos	56.39	0.00e+00	1407.00
IUUC-Xtr-132857	Xenopus tropicalis	54.53	0.00e+00	1324.00
IUUC-Yli-134399	Yarrowia lipolytica	51.69	0.00e+00	875.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence