iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ppe-101899

Ensembl Protein ID

EMJ11623

UniProt Accession

M5WQM6; M5WQM6_PRUPE

Genbank Protein ID

EMJ11623.1

Protein Name

Coatomer subunit alpha

Genbank Nucleotide ID

KB639086

Gene Name

PRUPE_ppa000386mg

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PRUPE_ppa000386mg	EMJ11623	EMJ11623

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-38	129.6	50	86
UBD/Beta-Prp	5.60e-76	256.1	3	323

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWDlrtgvll 36
           H ++v++++f  s +l+vsG+dD +ikvW+++ +++l
   Q: 50   HDGPVRGVHFhkSQPLFVSGGDDYKIKVWNYKMHRCL 86
           99*********7559***************9999887 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp 104
           t +++++++++ + f+ ++++++++  +g i++wd+++g+l+ ++ +h+++v+ v f+++++++v+g++D+ ikvw+++   c+ tl gh d++++++f+ 
   Q: 3    TKFETKSNRVKGLSFHSKRPWILASLHSGVIQLWDYRMGTLIDRFDEHDGPVRGVHFHKSQPLFVSGGDDYKIKVWNYKMHRCLFTLLGHLDYIRTVQFHH 103
           67889999********************************************************************************************* PP
   S: 105  sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...........................ktgkllrtltgg 178
           +  ++vs+s+d+tir+w++++++c++ +l+gh++ v+c+++hp+++l+vs+slD+tvr+Wd+                             + + + l+g 
   Q: 104  EYPWIVSASDDQTIRIWNWQSRTCIS-VLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIgslkkktvspaddilrlsqmntdlfggVDAVVKYVLEG- 202
           **************************.**************************************************77776666666433334444466. PP
   S: 179  htdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgd 277
           h++ v++ sf++n + +vsg++d++vklw +  ++   v+tl+gh +nv++v f+ +++++vs s+D+sir+Wd+++++ ++t+ +++++++  +  +++ 
   Q: 203  HDRGVNWASFHPNLPLIVSGADDRQVKLWRMNDTKAweVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKSIRVWDVTKRTGIQTFRREHDRFWILSS-HPEM 302
           ********************************777668*********************************************************9.6666 PP
   S: 278  nvlvlgsedskvniwklkknep 299
           n l++g  ds   ++kl++++p
   Q: 303  NLLAAG-HDSGMIVFKLERERP 323
           655555.689999999988765 PP

Organism

Prunus persica

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MLTKFETKSN RVKGLSFHSK RPWILASLHS GVIQLWDYRM GTLIDRFDEH DGPVRGVHFH 60
KSQPLFVSGG DDYKIKVWNY KMHRCLFTLL GHLDYIRTVQ FHHEYPWIVS ASDDQTIRIW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TATTTCTCTC TCTCTAGATA CACAACAACA TACGCACATC AGGTTCTGGA GGTAATCTTT 60
GGATGCATTA GTGAGTCATT TGGATCCCCT CACTTACTGA TCGGATCTAA GGTATAATTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011048--Haem_d1
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

KEGG

pper:PRUPE_ppa000386mg

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001758	Ailuropoda melanoleuca	54.74	0.00e+00	1375.00
IUUC-Atr-002493	Amborella trichopoda	82.18	0.00e+00	2038.00
IUUC-Apl-003385	Anas platyrhynchos	49.39	0.00e+00	1043.00
IUUC-Aca-005154	Anolis carolinensis	78.92	4.00e-96	342.00
IUUC-Aly-006020	Arabidopsis lyrata	83.03	0.00e+00	2066.00
IUUC-Ath-007360	Arabidopsis thaliana	83.00	0.00e+00	2070.00
IUUC-Acl-008027	Aspergillus clavatus	47.88	0.00e+00	1127.00
IUUC-Afl-008644	Aspergillus flavus	48.57	0.00e+00	1135.00
IUUC-Afu-008964	Aspergillus fumigatus	48.05	0.00e+00	1137.00
IUUC-Ani-009379	Aspergillus nidulans	55.84	0.00e+00	985.00
IUUC-Ang-009756	Aspergillus niger	48.12	0.00e+00	1141.00
IUUC-Aor-010174	Aspergillus oryzae	48.54	0.00e+00	1136.00
IUUC-Ate-010302	Aspergillus terreus	48.66	0.00e+00	1170.00
IUUC-Ame-011229	Astyanax mexicanus	53.28	0.00e+00	1331.00
IUUC-Bgr-012300	Blumeria graminis	47.56	0.00e+00	1090.00
IUUC-Bta-012524	Bos taurus	55.21	0.00e+00	1365.00
IUUC-Bci-013781	Botrytis cinerea	46.91	0.00e+00	1125.00
IUUC-Bol-015925	Brassica oleracea	82.65	0.00e+00	2049.00
IUUC-Bra-016978	Brassica rapa	83.05	0.00e+00	2060.00
IUUC-Cja-019107	Callithrix jacchus	54.38	0.00e+00	1356.00
IUUC-Cfa-020675	Canis familiaris	54.40	0.00e+00	1348.00
IUUC-Cpo-021813	Cavia porcellus	55.30	0.00e+00	1386.00
IUUC-Cre-022969	Chlamydomonas reinhardtii	72.00	0.00e+00	1280.00
IUUC-Csa-023523	Chlorocebus sabaeus	55.30	0.00e+00	1390.00
IUUC-Cho-024704	Choloepus hoffmanni	41.06	8.00e-173	600.00
IUUC-Csv-025864	Ciona savignyi	58.82	0.00e+00	1000.00
IUUC-Cgl-026510	Colletotrichum gloeosporioides	55.72	0.00e+00	977.00
IUUC-Cne-027053	Cryptococcus neoformans	51.05	0.00e+00	1184.00
IUUC-Cme-027222	Cyanidioschyzon merolae	41.83	1.00e-145	510.00
IUUC-Dre-027421	Danio rerio	54.89	0.00e+00	1365.00
IUUC-Dno-029303	Dasypus novemcinctus	55.38	0.00e+00	1392.00
IUUC-Dor-030290	Dipodomys ordii	52.99	2.00e-165	575.00
IUUC-Dse-031543	Dothistroma septosporum	46.43	0.00e+00	1071.00
IUUC-Dme-031945	Drosophila melanogaster	61.49	0.00e+00	1043.00
IUUC-Ete-032873	Echinops telfairi	53.20	0.00e+00	1222.00
IUUC-Eca-033773	Equus caballus	54.39	0.00e+00	1348.00
IUUC-Eeu-034874	Erinaceus europaeus	41.34	0.00e+00	653.00
IUUC-Fca-035739	Felis catus	54.47	0.00e+00	1355.00
IUUC-Fal-037263	Ficedula albicollis	51.06	0.00e+00	1209.00
IUUC-Fox-037738	Fusarium oxysporum	47.57	0.00e+00	1152.00
IUUC-Fso-038153	Fusarium solani	47.62	0.00e+00	1142.00
IUUC-Gmo-039602	Gadus morhua	50.85	0.00e+00	1238.00
IUUC-Ggr-039931	Gaeumannomyces graminis	55.10	0.00e+00	966.00
IUUC-Gga-040590	Gallus gallus	54.66	0.00e+00	1369.00
IUUC-Gac-041318	Gasterosteus aculeatus	54.17	0.00e+00	1351.00
IUUC-Gma-043257	Glycine max	86.33	0.00e+00	2154.00
IUUC-Ggo-045029	Gorilla gorilla	54.90	0.00e+00	1381.00
IUUC-Hsa-046078	Homo sapiens	54.90	0.00e+00	1380.00
IUUC-Itr-048881	Ictidomys tridecemlineatus	46.85	0.00e+00	778.00
IUUC-Lch-049706	Latimeria chalumnae	54.57	0.00e+00	1357.00
IUUC-Loc-051867	Lepisosteus oculatus	50.00	0.00e+00	819.00
IUUC-Lma-053138	Leptosphaeria maculans	55.35	0.00e+00	978.00
IUUC-Laf-053510	Loxodonta africana	55.26	0.00e+00	1382.00
IUUC-Mcc-055836	Macaca mulatta	54.90	0.00e+00	1378.00
IUUC-Meu-056238	Macropus eugenii	57.25	0.00e+00	784.00
IUUC-Mor-057172	Magnaporthe oryzae	47.08	0.00e+00	1120.00
IUUC-Mpo-057300	Magnaporthe poae	46.88	0.00e+00	1112.00
IUUC-Mtr-058248	Medicago truncatula	86.22	0.00e+00	2164.00
IUUC-Mga-059499	Meleagris gallopavo	54.57	0.00e+00	1365.00
IUUC-Mvi-060336	Microbotryum violaceum	50.43	0.00e+00	1225.00
IUUC-Mmr-061102	Microcebus murinus	54.90	0.00e+00	1371.00
IUUC-Mdo-062594	Monodelphis domestica	55.94	0.00e+00	1414.00
IUUC-Mmu-063736	Mus musculus	54.65	0.00e+00	1372.00
IUUC-Mpu-066701	Mustela putorius furo	54.66	0.00e+00	1367.00
IUUC-Mlu-067392	Myotis lucifugus	55.21	0.00e+00	1357.00
IUUC-Nfi-068270	Neosartorya fischeri	47.96	0.00e+00	1130.00
IUUC-Ncr-068892	Neurospora crassa	47.33	0.00e+00	1120.00
IUUC-Nle-069634	Nomascus leucogenys	66.02	0.00e+00	948.00
IUUC-Opr-070952	Ochotona princeps	41.05	0.00e+00	650.00
IUUC-Ont-072488	Oreochromis niloticus	54.29	0.00e+00	1343.00
IUUC-Ocu-074211	Oryctolagus cuniculus	55.21	0.00e+00	1381.00
IUUC-Oba-075761	Oryza barthii	78.26	0.00e+00	1986.00
IUUC-Ogl-077364	Oryza glaberrima	78.44	0.00e+00	1991.00
IUUC-Ogu-078257	Oryza glumaepatula	78.26	0.00e+00	1930.00
IUUC-Oin-079274	Oryza indica	78.36	0.00e+00	1991.00
IUUC-Olo-080466	Oryza longistaminata	83.23	0.00e+00	1495.00
IUUC-Oni-082874	Oryza nivara	78.44	0.00e+00	1992.00
IUUC-Oru-084274	Oryza rufipogon	78.44	0.00e+00	1992.00
IUUC-Osa-085565	Oryza sativa	78.44	0.00e+00	1992.00
IUUC-Ola-086921	Oryzias latipes	54.33	0.00e+00	1344.00
IUUC-Oga-087991	Otolemur garnettii	52.38	0.00e+00	1287.00
IUUC-Oar-089590	Ovis aries	55.13	0.00e+00	1384.00
IUUC-Ptr-090808	Pan troglodytes	54.98	0.00e+00	1382.00
IUUC-Pan-092475	Papio anubis	55.17	0.00e+00	1384.00
IUUC-Psi-093044	Pelodiscus sinensis	54.56	0.00e+00	895.00
IUUC-Pno-094839	Phaeosphaeria nodorum	45.89	0.00e+00	1048.00
IUUC-Ppa-095785	Physcomitrella patens	70.79	0.00e+00	1815.00
IUUC-Pfo-097493	Poecilia formosa	54.54	0.00e+00	1343.00
IUUC-Pab-098497	Pongo abelii	55.30	0.00e+00	1391.00
IUUC-Pop-099992	Populus trichocarpa	89.98	0.00e+00	2182.00
IUUC-Pva-102126	Pteropus vampyrus	52.76	0.00e+00	1307.00
IUUC-Pgr-103376	Puccinia graminis	59.35	0.00e+00	1048.00
IUUC-Ptt-103978	Puccinia triticina	53.86	0.00e+00	815.00
IUUC-Pte-104126	Pyrenophora teres	55.30	0.00e+00	932.00
IUUC-Pyt-104778	Pyrenophora triticirepentis	46.04	2.00e-174	605.00
IUUC-Rno-105428	Rattus norvegicus	54.97	0.00e+00	1379.00
IUUC-Sha-107301	Sarcophilus harrisii	54.90	0.00e+00	1368.00
IUUC-Sja-107961	Schizosaccharomyces japonicus	45.09	0.00e+00	1079.00
IUUC-Spo-108217	Schizosaccharomyces pombe	45.37	0.00e+00	1068.00
IUUC-Ssl-108643	Sclerotinia sclerotiorum	46.81	0.00e+00	1129.00
IUUC-Smo-109582	Selaginella moellendorffii	76.00	0.00e+00	1387.00
IUUC-Sar-113313	Sorex araneus	42.06	0.00e+00	650.00
IUUC-Sre-115209	Sporisorium reilianum	55.08	0.00e+00	992.00
IUUC-Ssc-115933	Sus scrofa	55.21	0.00e+00	1385.00
IUUC-Tgu-117109	Taeniopygia guttata	42.72	2.00e-109	389.00
IUUC-Tru-117772	Takifugu rubripes	53.57	0.00e+00	1310.00
IUUC-Tsy-119105	Tarsius syrichta	52.28	0.00e+00	1042.00
IUUC-Tni-120556	Tetraodon nigroviridis	42.06	0.00e+00	886.00
IUUC-Tca-120918	Theobroma cacao	88.93	0.00e+00	2195.00
IUUC-Tre-121951	Trichoderma reesei	46.93	0.00e+00	1114.00
IUUC-Tvi-122359	Trichoderma virens	47.58	0.00e+00	1140.00
IUUC-Tme-127170	Tuber melanosporum	48.82	0.00e+00	1186.00
IUUC-Ttr-128217	Tursiops truncatus	53.08	0.00e+00	1312.00
IUUC-Uma-129337	Ustilago maydis	55.56	0.00e+00	994.00
IUUC-Vda-129828	Verticillium dahliae	47.04	0.00e+00	1109.00
IUUC-Vpa-130537	Vicugna pacos	54.49	0.00e+00	1357.00
IUUC-Xtr-132857	Xenopus tropicalis	53.42	0.00e+00	1300.00
IUUC-Xma-133138	Xiphophorus maculatus	54.54	0.00e+00	1345.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence