iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Stu-112564

Ensembl Protein ID

PGSC0003DMT400009636

UniProt Accession

M0ZWP5; M0ZWP5_SOLTU

Protein Name

Coatomer subunit alpha

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PGSC0003DMG400003762	PGSC0003DMT400009636	PGSC0003DMT400009636

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.70e-37	125.9	50	85
UBD/Beta-Prp	1.90e-76	258.3	3	323

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWDlrtgvl 35
           H ++v++++f  s +l+vsG+dD +ikvW+++ +++
   Q: 50   HDGPVRGVHFhkSQPLFVSGGDDYKIKVWNYKLHRC 85
           99*********7559***************876666 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkg 92
           t +++++++++ + f+ ++++++++  +g i++wd+++g+l+ ++ +h+++v+ v f+++++++v+g++D+ ikvw+++   c+ tl g
   Q: 3    TKFETKSNRVKGLSFHSKRPWILASLHSGVIQLWDYRMGTLIDRFDEHDGPVRGVHFHKSQPLFVSGGDDYKIKVWNYKLHRCLFTLLG 91
           67889999********************************************************************************* PP
   S: 93   hedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl............... 166
           h d++++++f+ +  ++vs+s+d+tir+w++++++c++ +l+gh++ v+c+ +hp+++l+vs+slD+tvr+Wd+               
   Q: 92   HLDYIRTVQFHHEYPWIVSASDDQTIRIWNWQSRTCIS-VLTGHNHYVMCALFHPKEDLVVSASLDQTVRVWDIgalrkktvspaddil 179
           **************************************.************************************************** PP
   S: 167  ...........ktgkllrtl........tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnd 234
                                       +g h++ v++ sf+++ + +vsg++d++vk+w +  ++   v+tl+gh +nv++v f++++
   Q: 180  rlsqmntdffgG-------VdavvkyvlEG-HDRGVNWASFHPTLPLIVSGADDRQVKIWRMNDTKAweVDTLRGHMNNVSCVLFHSRQ 260
           555555555552.......05555555365.********************************777668******************** PP
   S: 235  erlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvniwklkknep 299
           +++vs s+D+sir+Wd ++++ l+t+ +++++++  a+ +++ n l++g  ds   ++kl++++p
   Q: 261  DIIVSNSEDKSIRVWDATKRTGLQTFRREHDRFWILAA-HPEMNLLAAG-HDSGMIVFKLERERP 323
           **************************************.6666655555.689999999988765 PP

Organism

Solanum tuberosum

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MLTKFETKSN RVKGLSFHSK RPWILASLHS GVIQLWDYRM GTLIDRFDEH DGPVRGVHFH 60
KSQPLFVSGG DDYKIKVWNY KLHRCLFTLL GHLDYIRTVQ FHHEYPWIVS ASDDQTIRIW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGAGACTATA TTATTCTTCT GTCTATCAAA CTTCCGATCC CCAATTTCTT TAACGCACAC 60
TAAAAAATAC ACCCAAAGAG ACAACTTCCC TTAACATACG CACTCTCCGT TCACCGATCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

KEGG

sot:102582145

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000064	Aegilops tauschii	84.16	0.00e+00	1501.00
IUUC-Aml-001758	Ailuropoda melanoleuca	54.79	0.00e+00	1356.00
IUUC-Atr-002493	Amborella trichopoda	81.53	0.00e+00	2005.00
IUUC-Apl-003385	Anas platyrhynchos	49.35	0.00e+00	1041.00
IUUC-Aca-005154	Anolis carolinensis	77.99	3.00e-96	342.00
IUUC-Aly-006020	Arabidopsis lyrata	82.20	0.00e+00	2034.00
IUUC-Ath-007058	Arabidopsis thaliana	82.12	0.00e+00	2034.00
IUUC-Ago-007992	Ashbya gossypii	43.40	0.00e+00	954.00
IUUC-Acl-008027	Aspergillus clavatus	55.80	0.00e+00	972.00
IUUC-Afl-008644	Aspergillus flavus	55.35	0.00e+00	964.00
IUUC-Afu-008964	Aspergillus fumigatus	47.04	0.00e+00	1118.00
IUUC-Ani-009379	Aspergillus nidulans	55.25	0.00e+00	981.00
IUUC-Ang-009756	Aspergillus niger	47.03	0.00e+00	1115.00
IUUC-Aor-010174	Aspergillus oryzae	55.35	0.00e+00	964.00
IUUC-Ate-010302	Aspergillus terreus	46.80	0.00e+00	1133.00
IUUC-Ame-011229	Astyanax mexicanus	54.13	0.00e+00	1334.00
IUUC-Bgr-012300	Blumeria graminis	46.34	0.00e+00	1072.00
IUUC-Bta-012524	Bos taurus	55.27	0.00e+00	1348.00
IUUC-Bci-013781	Botrytis cinerea	47.24	0.00e+00	1117.00
IUUC-Bdi-014549	Brachypodium distachyon	78.11	0.00e+00	2018.00
IUUC-Bol-015925	Brassica oleracea	80.93	0.00e+00	2001.00
IUUC-Bra-016978	Brassica rapa	81.33	0.00e+00	2013.00
IUUC-Cel-018115	Caenorhabditis elegans	56.40	0.00e+00	951.00
IUUC-Cja-019107	Callithrix jacchus	54.36	0.00e+00	1338.00
IUUC-Cfa-020675	Canis familiaris	54.46	0.00e+00	1327.00
IUUC-Cpo-021813	Cavia porcellus	55.43	0.00e+00	1367.00
IUUC-Cre-022969	Chlamydomonas reinhardtii	72.24	0.00e+00	1286.00
IUUC-Csa-023523	Chlorocebus sabaeus	55.43	0.00e+00	1372.00
IUUC-Cho-024704	Choloepus hoffmanni	69.77	2.00e-133	469.00
IUUC-Cin-025572	Ciona intestinalis	50.72	0.00e+00	1241.00
IUUC-Csv-025864	Ciona savignyi	57.98	0.00e+00	988.00
IUUC-Cgl-026510	Colletotrichum gloeosporioides	55.32	0.00e+00	980.00
IUUC-Cne-027053	Cryptococcus neoformans	51.49	0.00e+00	1196.00
IUUC-Cme-027222	Cyanidioschyzon merolae	40.86	4.00e-148	518.00
IUUC-Dre-027421	Danio rerio	55.28	0.00e+00	1352.00
IUUC-Dno-029303	Dasypus novemcinctus	55.48	0.00e+00	1374.00
IUUC-Dor-030290	Dipodomys ordii	52.72	2.00e-163	569.00
IUUC-Dse-031543	Dothistroma septosporum	46.18	0.00e+00	1056.00
IUUC-Dme-031945	Drosophila melanogaster	62.33	0.00e+00	1039.00
IUUC-Ete-032873	Echinops telfairi	60.48	0.00e+00	1049.00
IUUC-Eca-033773	Equus caballus	54.40	0.00e+00	1328.00
IUUC-Eeu-034874	Erinaceus europaeus	41.82	0.00e+00	664.00
IUUC-Fca-035739	Felis catus	52.93	0.00e+00	1313.00
IUUC-Fal-037263	Ficedula albicollis	51.42	0.00e+00	1214.00
IUUC-Fox-037738	Fusarium oxysporum	47.24	0.00e+00	1121.00
IUUC-Fso-038153	Fusarium solani	46.99	0.00e+00	1115.00
IUUC-Gmo-039602	Gadus morhua	51.25	0.00e+00	1240.00
IUUC-Ggr-039931	Gaeumannomyces graminis	54.12	0.00e+00	965.00
IUUC-Gga-040590	Gallus gallus	54.76	0.00e+00	1369.00
IUUC-Gac-041318	Gasterosteus aculeatus	54.74	0.00e+00	1355.00
IUUC-Gma-043894	Glycine max	82.53	0.00e+00	2073.00
IUUC-Ggo-045029	Gorilla gorilla	55.03	0.00e+00	1363.00
IUUC-Hsa-046078	Homo sapiens	54.95	0.00e+00	1362.00
IUUC-Hvu-047556	Hordeum vulgare	78.36	0.00e+00	2011.00
IUUC-Itr-048881	Ictidomys tridecemlineatus	46.36	0.00e+00	754.00
IUUC-Kpa-049256	Komagataella pastoris	45.37	0.00e+00	1051.00
IUUC-Lch-049706	Latimeria chalumnae	54.97	0.00e+00	1360.00
IUUC-Lpe-051316	Leersia perrieri	78.77	0.00e+00	1991.00
IUUC-Loc-051867	Lepisosteus oculatus	50.70	0.00e+00	825.00
IUUC-Lma-053138	Leptosphaeria maculans	54.88	0.00e+00	993.00
IUUC-Laf-053510	Loxodonta africana	55.92	0.00e+00	1391.00
IUUC-Mcc-055836	Macaca mulatta	54.96	0.00e+00	1359.00
IUUC-Meu-056238	Macropus eugenii	56.72	0.00e+00	772.00
IUUC-Mor-057172	Magnaporthe oryzae	46.26	0.00e+00	1104.00
IUUC-Mpo-057300	Magnaporthe poae	46.15	0.00e+00	1097.00
IUUC-Mtr-058248	Medicago truncatula	81.79	0.00e+00	2075.00
IUUC-Mla-059019	Melampsora laricipopulina	50.81	0.00e+00	1234.00
IUUC-Mga-059499	Meleagris gallopavo	54.67	0.00e+00	1365.00
IUUC-Mvi-060336	Microbotryum violaceum	51.85	0.00e+00	1232.00
IUUC-Mmr-061102	Microcebus murinus	54.55	0.00e+00	1347.00
IUUC-Mdo-062594	Monodelphis domestica	55.91	0.00e+00	1393.00
IUUC-Mmu-063736	Mus musculus	54.79	0.00e+00	1354.00
IUUC-Mac-065398	Musa acuminata	74.96	0.00e+00	1862.00
IUUC-Mpu-066701	Mustela putorius furo	55.31	0.00e+00	1369.00
IUUC-Mlu-067392	Myotis lucifugus	55.17	0.00e+00	1357.00
IUUC-Nfi-068270	Neosartorya fischeri	55.92	0.00e+00	975.00
IUUC-Ncr-068892	Neurospora crassa	56.27	0.00e+00	988.00
IUUC-Nle-069634	Nomascus leucogenys	66.07	0.00e+00	944.00
IUUC-Opr-070952	Ochotona princeps	42.12	0.00e+00	654.00
IUUC-Ont-072488	Oreochromis niloticus	54.49	0.00e+00	1344.00
IUUC-Ocu-074211	Oryctolagus cuniculus	55.27	0.00e+00	1362.00
IUUC-Oba-075761	Oryza barthii	79.16	0.00e+00	1996.00
IUUC-Obr-076429	Oryza brachyantha	84.16	0.00e+00	1506.00
IUUC-Ogl-077364	Oryza glaberrima	84.85	0.00e+00	1513.00
IUUC-Ogu-078257	Oryza glumaepatula	84.73	0.00e+00	1510.00
IUUC-Oin-079274	Oryza indica	84.73	0.00e+00	1511.00
IUUC-Olo-080466	Oryza longistaminata	84.33	0.00e+00	1491.00
IUUC-Ome-081993	Oryza meridionalis	84.74	0.00e+00	1389.00
IUUC-Oni-082874	Oryza nivara	84.85	0.00e+00	1512.00
IUUC-Opu-083885	Oryza punctata	79.84	0.00e+00	2005.00
IUUC-Oru-084274	Oryza rufipogon	84.73	0.00e+00	1510.00
IUUC-Osa-085565	Oryza sativa	84.73	0.00e+00	1510.00
IUUC-Ola-086921	Oryzias latipes	53.17	0.00e+00	1332.00
IUUC-Olu-087639	Ostreococcus lucimarinus	62.51	0.00e+00	1580.00
IUUC-Oga-087991	Otolemur garnettii	52.17	0.00e+00	1267.00
IUUC-Oar-089590	Ovis aries	55.19	0.00e+00	1365.00
IUUC-Ptr-090808	Pan troglodytes	55.03	0.00e+00	1364.00
IUUC-Pan-092475	Papio anubis	55.14	0.00e+00	1364.00
IUUC-Psi-093044	Pelodiscus sinensis	55.62	0.00e+00	909.00
IUUC-Pno-094839	Phaeosphaeria nodorum	53.71	0.00e+00	920.00
IUUC-Ppa-095254	Physcomitrella patens	71.50	0.00e+00	1821.00
IUUC-Pfo-097493	Poecilia formosa	54.56	0.00e+00	1342.00
IUUC-Pab-098497	Pongo abelii	55.35	0.00e+00	1373.00
IUUC-Pop-099992	Populus trichocarpa	84.81	0.00e+00	2083.00
IUUC-Pca-100413	Procavia capensis	60.61	0.00e+00	693.00
IUUC-Ppe-101392	Prunus persica	86.54	0.00e+00	2198.00
IUUC-Pva-102126	Pteropus vampyrus	52.72	0.00e+00	1283.00
IUUC-Pgr-103376	Puccinia graminis	50.20	0.00e+00	1234.00
IUUC-Ptt-103978	Puccinia triticina	52.89	0.00e+00	816.00
IUUC-Pte-104126	Pyrenophora teres	54.84	0.00e+00	950.00
IUUC-Pyt-104778	Pyrenophora triticirepentis	45.94	8.00e-179	619.00
IUUC-Rno-105428	Rattus norvegicus	55.35	0.00e+00	1366.00
IUUC-Sce-106464	Saccharomyces cerevisiae	41.58	0.00e+00	927.00
IUUC-Sha-107301	Sarcophilus harrisii	54.70	0.00e+00	1347.00
IUUC-Sja-107961	Schizosaccharomyces japonicus	44.84	0.00e+00	1068.00
IUUC-Spo-108217	Schizosaccharomyces pombe	44.89	0.00e+00	1050.00
IUUC-Ssl-108643	Sclerotinia sclerotiorum	47.27	0.00e+00	1122.00
IUUC-Smo-109582	Selaginella moellendorffii	75.38	0.00e+00	1385.00
IUUC-Sit-109697	Setaria italica	79.46	0.00e+00	1995.00
IUUC-Sly-111759	Solanum lycopersicum	98.93	0.00e+00	2440.00
IUUC-Sar-113313	Sorex araneus	41.80	0.00e+00	632.00
IUUC-Sbi-114388	Sorghum bicolor	79.38	0.00e+00	1988.00
IUUC-Sre-115209	Sporisorium reilianum	55.57	0.00e+00	1012.00
IUUC-Ssc-115933	Sus scrofa	55.27	0.00e+00	1366.00
IUUC-Tgu-117109	Taeniopygia guttata	43.50	2.00e-112	398.00
IUUC-Tru-117772	Takifugu rubripes	53.83	0.00e+00	1311.00
IUUC-Tsy-119105	Tarsius syrichta	52.87	0.00e+00	1050.00
IUUC-Tni-120556	Tetraodon nigroviridis	42.02	0.00e+00	887.00
IUUC-Tca-121046	Theobroma cacao	84.28	0.00e+00	2133.00
IUUC-Tre-121951	Trichoderma reesei	55.32	0.00e+00	973.00
IUUC-Tvi-122359	Trichoderma virens	46.19	0.00e+00	1115.00
IUUC-Tae-123611	Triticum aestivum	84.16	0.00e+00	1501.00
IUUC-Tur-126754	Triticum urartu	76.29	0.00e+00	1932.00
IUUC-Tme-127170	Tuber melanosporum	47.79	0.00e+00	1165.00
IUUC-Tbe-127882	Tupaia belangeri	69.68	1.00e-129	456.00
IUUC-Ttr-128217	Tursiops truncatus	53.12	0.00e+00	1291.00
IUUC-Uma-129337	Ustilago maydis	56.16	0.00e+00	1012.00
IUUC-Vda-129828	Verticillium dahliae	53.09	0.00e+00	949.00
IUUC-Vpa-130537	Vicugna pacos	54.71	0.00e+00	1340.00
IUUC-Vvi-130958	Vitis vinifera	86.04	0.00e+00	2150.00
IUUC-Xtr-132857	Xenopus tropicalis	53.16	0.00e+00	1271.00
IUUC-Xma-133138	Xiphophorus maculatus	54.48	0.00e+00	1342.00
IUUC-Yli-134399	Yarrowia lipolytica	49.42	0.00e+00	842.00
IUUC-Zma-135612	Zea mays	77.93	0.00e+00	1998.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence