iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tme-127170

Ensembl Protein ID

CAZ81694

UniProt Accession

D5GB01; D5GB01_TUBMM

Genbank Protein ID

CAZ81694.1

Protein Name

Coatomer subunit alpha

Genbank Nucleotide ID

FN430086

Gene Name

GSTUM_00005379001

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
GSTUM_00005379001	CAZ81694	CAZ81694

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.60e-33	109.5	53	89
UBD/Beta-Prp	1.00e-75	253.3	5	331

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           H ++v++++f  + +l+vsG+dD +ikvW++ t ++l
   Q: 53   HDGPVRGIDFhCTqPLFVSGGDDYKIKVWSYQTRRCL 89
           99********95559***************9999887 PP

UBD/Beta-Prp

   S: 3    ktlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfs 103
            t +++++s+ + ++f+p++++++++  ++ti++wd+++g+l+ ++++h+++v+ ++f+ +++++v+g++D+ ikvw+++t+ c+ tl+gh d+v+++ f+
   Q: 5    LTKFESKSSRAKGIAFHPKRPWILVSLHTSTIQLWDYRMGTLIDRFEEHDGPVRGIDFHCTQPLFVSGGDDYKIKVWSYQTRRCLFTLNGHLDYVRTVFFH 105
           67889999********************************************************************************************* PP
   S: 104  psgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...............................ktgkllr 173
            +  +++s s+d+tir+w++++++ +  t +gh++ ++c+++hp+++l+vs+slD+ vr+Wd+                               +t+ +++
   Q: 106  HELPWILSSSDDQTIRIWNWQNRSLIC-TMTGHNHYTMCAQFHPKEDLIVSASLDQSVRVWDIsglrkkhsaptsmtfedqmarananqadmfgNTDAVVK 205
           **************************9.********************************************************99999999977777777 PP
   S: 174  tltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvav 272
              +gh++ v+++sf+++ + ++s+++d+ vklw +++++   v+t++gh +n +   f+p++++++s+++D+++r+Wdl +++ +++++++n++++ +a+
   Q: 206  FVLEGHDRGVNWVSFHPTLPLIISAGDDRNVKLWRMSETKAweVDTCRGHFQNSSACLFHPHQDLILSVGEDKTVRVWDLNKRTAVQSFKRENDRFWVIAA 306
           66777********************************888778********************************************************** PP
   S: 273  lsfgdnvlvlgsedskvniwklkknep 299
            +++ n +++g  d+ v+++kl++++p
   Q: 307  -HPEINLFAAG-HDNGVMVFKLERERP 331
           .6666555555.478*******98775 PP

Organism

Tuber melanosporum

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MQSMLTKFES KSSRAKGIAF HPKRPWILVS LHTSTIQLWD YRMGTLIDRF EEHDGPVRGI 60
DFHCTQPLFV SGGDDYKIKV WSYQTRRCLF TLNGHLDYVR TVFFHHELPW ILSSSDDQTI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAACATCGTA ACGATCCCCA CGCCTCCACT TGAATCTCCT CCTCTTAACT CCTTTCCCTT 60
TTACCTGAAC TTGATACCCG AAGCTGAGGA GAAGACCCTC TTCTGCCTAG TGTATTCCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011048--Haem_d1
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER

KEGG

tml:GSTUM_00005379001

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000064	Aegilops tauschii	47.12	0.00e+00	1156.00
IUUC-Aml-001758	Ailuropoda melanoleuca	50.12	0.00e+00	1236.00
IUUC-Atr-002493	Amborella trichopoda	55.66	0.00e+00	976.00
IUUC-Apl-003385	Anas platyrhynchos	45.32	0.00e+00	921.00
IUUC-Aca-005154	Anolis carolinensis	71.84	3.00e-93	332.00
IUUC-Aly-006020	Arabidopsis lyrata	55.34	0.00e+00	977.00
IUUC-Ath-007360	Arabidopsis thaliana	55.94	0.00e+00	986.00
IUUC-Ago-007992	Ashbya gossypii	53.92	0.00e+00	1307.00
IUUC-Acl-008027	Aspergillus clavatus	76.61	0.00e+00	1909.00
IUUC-Afl-008644	Aspergillus flavus	76.42	0.00e+00	1914.00
IUUC-Afu-008964	Aspergillus fumigatus	76.54	0.00e+00	1931.00
IUUC-Ani-009379	Aspergillus nidulans	82.49	0.00e+00	1507.00
IUUC-Ang-009756	Aspergillus niger	76.82	0.00e+00	1928.00
IUUC-Aor-010174	Aspergillus oryzae	76.34	0.00e+00	1910.00
IUUC-Ate-010302	Aspergillus terreus	75.74	0.00e+00	1955.00
IUUC-Ame-011229	Astyanax mexicanus	55.36	0.00e+00	1017.00
IUUC-Bgr-012300	Blumeria graminis	73.11	0.00e+00	1833.00
IUUC-Bta-012524	Bos taurus	50.49	0.00e+00	1233.00
IUUC-Bci-013781	Botrytis cinerea	76.15	0.00e+00	1925.00
IUUC-Bdi-014549	Brachypodium distachyon	46.44	0.00e+00	1151.00
IUUC-Bol-015925	Brassica oleracea	55.94	0.00e+00	982.00
IUUC-Bra-016978	Brassica rapa	55.34	0.00e+00	978.00
IUUC-Cel-018115	Caenorhabditis elegans	52.76	0.00e+00	924.00
IUUC-Cja-019107	Callithrix jacchus	49.31	0.00e+00	1217.00
IUUC-Cfa-020675	Canis familiaris	49.84	0.00e+00	1209.00
IUUC-Cpo-021813	Cavia porcellus	50.57	0.00e+00	1248.00
IUUC-Cre-022969	Chlamydomonas reinhardtii	56.62	0.00e+00	1009.00
IUUC-Csa-023523	Chlorocebus sabaeus	50.57	0.00e+00	1250.00
IUUC-Cho-024704	Choloepus hoffmanni	39.30	5.00e-154	536.00
IUUC-Cin-025572	Ciona intestinalis	47.39	0.00e+00	1179.00
IUUC-Csv-025864	Ciona savignyi	55.42	0.00e+00	953.00
IUUC-Cgl-026510	Colletotrichum gloeosporioides	75.08	0.00e+00	1898.00
IUUC-Cne-027053	Cryptococcus neoformans	55.76	0.00e+00	1354.00
IUUC-Cme-027222	Cyanidioschyzon merolae	40.18	4.00e-144	504.00
IUUC-Dre-027421	Danio rerio	49.96	0.00e+00	1231.00
IUUC-Dno-029303	Dasypus novemcinctus	50.49	0.00e+00	1249.00
IUUC-Dor-030290	Dipodomys ordii	46.67	8.00e-149	519.00
IUUC-Dse-031543	Dothistroma septosporum	72.80	0.00e+00	1779.00
IUUC-Dme-031945	Drosophila melanogaster	56.62	0.00e+00	972.00
IUUC-Ete-032873	Echinops telfairi	48.09	0.00e+00	1083.00
IUUC-Eca-033773	Equus caballus	49.04	0.00e+00	1194.00
IUUC-Eeu-034874	Erinaceus europaeus	38.41	9.00e-168	582.00
IUUC-Fca-035739	Felis catus	49.76	0.00e+00	1220.00
IUUC-Fal-037263	Ficedula albicollis	46.44	0.00e+00	1092.00
IUUC-Fox-037738	Fusarium oxysporum	73.11	0.00e+00	1915.00
IUUC-Fso-038153	Fusarium solani	74.07	0.00e+00	1919.00
IUUC-Gmo-039602	Gadus morhua	48.03	0.00e+00	1155.00
IUUC-Ggr-039931	Gaeumannomyces graminis	82.06	0.00e+00	1504.00
IUUC-Gga-040590	Gallus gallus	49.96	0.00e+00	1234.00
IUUC-Gac-041318	Gasterosteus aculeatus	49.60	0.00e+00	1222.00
IUUC-Gma-043894	Glycine max	48.38	0.00e+00	1168.00
IUUC-Ggo-045029	Gorilla gorilla	50.20	0.00e+00	1241.00
IUUC-Hsa-046078	Homo sapiens	50.20	0.00e+00	1242.00
IUUC-Hvu-047556	Hordeum vulgare	46.17	0.00e+00	1148.00
IUUC-Itr-048881	Ictidomys tridecemlineatus	42.53	0.00e+00	675.00
IUUC-Kpa-049256	Komagataella pastoris	56.27	0.00e+00	1417.00
IUUC-Lch-049706	Latimeria chalumnae	50.20	0.00e+00	1222.00
IUUC-Lpe-051316	Leersia perrieri	55.54	0.00e+00	987.00
IUUC-Loc-051867	Lepisosteus oculatus	39.28	0.00e+00	828.00
IUUC-Lma-053138	Leptosphaeria maculans	73.78	0.00e+00	1860.00
IUUC-Laf-053510	Loxodonta africana	50.57	0.00e+00	1241.00
IUUC-Mcc-055836	Macaca mulatta	50.20	0.00e+00	1243.00
IUUC-Meu-056238	Macropus eugenii	51.47	0.00e+00	710.00
IUUC-Mor-057172	Magnaporthe oryzae	75.12	0.00e+00	1907.00
IUUC-Mpo-057300	Magnaporthe poae	72.71	0.00e+00	1872.00
IUUC-Mtr-058248	Medicago truncatula	47.22	0.00e+00	1168.00
IUUC-Mla-059019	Melampsora laricipopulina	57.48	0.00e+00	1436.00
IUUC-Mga-059499	Meleagris gallopavo	49.96	0.00e+00	1230.00
IUUC-Mvi-060336	Microbotryum violaceum	55.67	0.00e+00	1406.00
IUUC-Mmr-061102	Microcebus murinus	50.12	0.00e+00	1235.00
IUUC-Mdo-062594	Monodelphis domestica	50.69	0.00e+00	1257.00
IUUC-Mmu-063736	Mus musculus	50.00	0.00e+00	1237.00
IUUC-Mac-065398	Musa acuminata	42.06	0.00e+00	907.00
IUUC-Mpu-066701	Mustela putorius furo	50.16	0.00e+00	1229.00
IUUC-Mlu-067392	Myotis lucifugus	50.04	0.00e+00	1231.00
IUUC-Nfi-068270	Neosartorya fischeri	76.77	0.00e+00	1916.00
IUUC-Ncr-068892	Neurospora crassa	73.05	0.00e+00	1883.00
IUUC-Nle-069634	Nomascus leucogenys	60.00	0.00e+00	876.00
IUUC-Opr-070952	Ochotona princeps	39.58	5.00e-175	606.00
IUUC-Ont-072488	Oreochromis niloticus	49.55	0.00e+00	1214.00
IUUC-Ocu-074211	Oryctolagus cuniculus	50.32	0.00e+00	1242.00
IUUC-Oba-075761	Oryza barthii	55.66	0.00e+00	990.00
IUUC-Obr-076429	Oryza brachyantha	55.66	0.00e+00	991.00
IUUC-Ogl-077364	Oryza glaberrima	55.66	0.00e+00	991.00
IUUC-Ogu-078257	Oryza glumaepatula	55.66	0.00e+00	987.00
IUUC-Oin-079274	Oryza indica	55.54	0.00e+00	989.00
IUUC-Olo-080466	Oryza longistaminata	55.86	0.00e+00	984.00
IUUC-Ome-081668	Oryza meridionalis	55.76	0.00e+00	839.00
IUUC-Oni-082874	Oryza nivara	55.46	0.00e+00	990.00
IUUC-Opu-083885	Oryza punctata	55.66	0.00e+00	990.00
IUUC-Oru-084274	Oryza rufipogon	55.66	0.00e+00	991.00
IUUC-Osa-085565	Oryza sativa	55.66	0.00e+00	991.00
IUUC-Ola-086921	Oryzias latipes	49.48	0.00e+00	1219.00
IUUC-Olu-087639	Ostreococcus lucimarinus	48.62	0.00e+00	1181.00
IUUC-Oga-087991	Otolemur garnettii	48.14	0.00e+00	1158.00
IUUC-Oar-089590	Ovis aries	50.57	0.00e+00	1243.00
IUUC-Ptr-090808	Pan troglodytes	50.20	0.00e+00	1241.00
IUUC-Pan-092475	Papio anubis	50.28	0.00e+00	1238.00
IUUC-Psi-093044	Pelodiscus sinensis	53.38	0.00e+00	867.00
IUUC-Pno-094839	Phaeosphaeria nodorum	72.88	0.00e+00	1791.00
IUUC-Ppa-095785	Physcomitrella patens	49.80	0.00e+00	1233.00
IUUC-Pfo-097493	Poecilia formosa	49.63	0.00e+00	1221.00
IUUC-Pab-098497	Pongo abelii	50.49	0.00e+00	1249.00
IUUC-Pop-099992	Populus trichocarpa	56.26	0.00e+00	986.00
IUUC-Pca-100413	Procavia capensis	54.12	0.00e+00	635.00
IUUC-Ppe-101899	Prunus persica	55.94	0.00e+00	991.00
IUUC-Pva-102126	Pteropus vampyrus	48.51	0.00e+00	1176.00
IUUC-Pgr-103376	Puccinia graminis	57.44	0.00e+00	1459.00
IUUC-Ptt-103978	Puccinia triticina	51.65	0.00e+00	1243.00
IUUC-Pte-104126	Pyrenophora teres	73.31	0.00e+00	1812.00
IUUC-Pyt-104778	Pyrenophora triticirepentis	66.33	0.00e+00	1407.00
IUUC-Rno-105428	Rattus norvegicus	50.45	0.00e+00	1243.00
IUUC-Sce-106464	Saccharomyces cerevisiae	53.34	0.00e+00	1280.00
IUUC-Sha-107301	Sarcophilus harrisii	50.29	0.00e+00	1227.00
IUUC-Sja-107961	Schizosaccharomyces japonicus	53.17	0.00e+00	1343.00
IUUC-Spo-108217	Schizosaccharomyces pombe	55.28	0.00e+00	1387.00
IUUC-Ssl-108643	Sclerotinia sclerotiorum	76.87	0.00e+00	1928.00
IUUC-Smo-109582	Selaginella moellendorffii	57.14	0.00e+00	1019.00
IUUC-Sit-109697	Setaria italica	55.54	0.00e+00	989.00
IUUC-Sly-111447	Solanum lycopersicum	47.11	0.00e+00	1164.00
IUUC-Stu-112564	Solanum tuberosum	47.39	0.00e+00	1162.00
IUUC-Sar-113313	Sorex araneus	41.86	3.00e-163	566.00
IUUC-Sbi-114388	Sorghum bicolor	47.56	0.00e+00	1155.00
IUUC-Sre-115209	Sporisorium reilianum	61.99	0.00e+00	1150.00
IUUC-Ssc-115933	Sus scrofa	50.57	0.00e+00	1245.00
IUUC-Tgu-117109	Taeniopygia guttata	40.08	1.00e-97	348.00
IUUC-Tru-117772	Takifugu rubripes	48.76	0.00e+00	1200.00
IUUC-Tsy-119105	Tarsius syrichta	47.40	0.00e+00	938.00
IUUC-Tni-120556	Tetraodon nigroviridis	38.18	0.00e+00	790.00
IUUC-Tca-121046	Theobroma cacao	48.08	0.00e+00	1174.00
IUUC-Tre-121951	Trichoderma reesei	73.37	0.00e+00	1859.00
IUUC-Tvi-122359	Trichoderma virens	73.43	0.00e+00	1888.00
IUUC-Tae-123611	Triticum aestivum	47.12	0.00e+00	1156.00
IUUC-Tur-126754	Triticum urartu	47.46	0.00e+00	1147.00
IUUC-Tbe-127882	Tupaia belangeri	61.86	5.00e-121	427.00
IUUC-Ttr-128217	Tursiops truncatus	48.59	0.00e+00	1175.00
IUUC-Uma-129337	Ustilago maydis	61.40	0.00e+00	1140.00
IUUC-Vda-129828	Verticillium dahliae	71.76	0.00e+00	1845.00
IUUC-Vpa-130537	Vicugna pacos	49.96	0.00e+00	1225.00
IUUC-Vvi-130958	Vitis vinifera	55.88	0.00e+00	994.00
IUUC-Xtr-132857	Xenopus tropicalis	48.86	0.00e+00	1165.00
IUUC-Xma-133138	Xiphophorus maculatus	49.63	0.00e+00	1222.00
IUUC-Yli-134399	Yarrowia lipolytica	60.88	0.00e+00	1079.00
IUUC-Zma-135612	Zea mays	45.88	0.00e+00	1150.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence