iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000021547.3	ENSXETT00000046564.2	ENSXETP00000046564.2
ENSXETG00000021547.3	ENSXETT00000046566.2	ENSXETP00000046566.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.70e-103	344.8	259	588

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgy 87
           +Gl+NlgNtC+mNS+LQcLsn+++lr+++l+ +++++l+    k+ ++++++++++l++++w +s +++vsp+e++++++k+a++f gy
   Q: 259  VGLRNLGNTCFMNSILQCLSNTKDLRDYCLQnSYRRDLSS---KKCNTAIMEEFARLLQAIWtSSANEVVSPSEFKTQIQKYAPRFMGY 344
           6******************************555555544...57899**************9999*********************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde...aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldls 173
           +qqDaqEfl+flld+l++e+++ + kp+ ++++ d+   s++    +++  ++++s i++lF gqlks+++c ec+  s+ ++pf+dls
   Q: 345  NQQDAQEFLRFLLDGLHNEVNRVTVKPRPSSQDLDHMPDSEKgkhMWKRYLEREDSRIVELFVGQLKSSLTCTECGYCSTVFDPFWDLS 433
           **********************888888888887755444446669******************************************* PP
   S: 174  lpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldl 261
           lp+ +k+  ++ sl dc++ ftke+ l+g++k  c +ck++++++kk++++k+P++L+lhLkRf  se + ++ k+++ v+fpl+ Ldl
   Q: 434  LPIAKKSA-SEVSLVDCMRLFTKEDVLDGDEKPTCCRCKARRRCTKKFTIQKFPKILVLHLKRF--SEGRIRSGKLSTFVNFPLKdLDL 519
           ****9995.688****************************************************..88999****************** PP
   S: 262  spfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYk 336
           ++f ++++     + +Y+L+av +HsG++ +GHY+ay+kn +++ W++f+Ds+Vt+++ ++v +   s+aYvlfY+
   Q: 520  REFSSESN----PHATYNLYAVSNHSGTTMGGHYTAYCKNPSNGeWYTFNDSRVTAMSSNQVRS---SDAYVLFYE 588
           ****9944....378*************************66555*******************...********8 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MSHSSSTLKR YTDTSYTKSY GSFSSYTSNL NSSYIDRDKI PYKTSFGSSY LSSSPHLRSY 60
PELERSLPRL DVTSKRTDIV GRSTSKYGTS NFPTYSYGYN TTYSPITASP VTSLTRRKSS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCCACT CTTCCTCTAC CCTCAAGAGA TATACAGATA CATCTTATAC CAAAAGTTAT 60
GGGAGCTTCA GCTCATACAC CTCCAATCTC AATTCATCCT ACATTGACCG TGATAAAATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001988	Ailuropoda melanoleuca	57.74	0.00e+00	643.00
IUUC-Aca-005132	Anolis carolinensis	56.50	4.00e-174	604.00
IUUC-Ame-011102	Astyanax mexicanus	75.64	1.00e-147	515.00
IUUC-Bta-012529	Bos taurus	56.34	6.00e-173	600.00
IUUC-Cel-018186	Caenorhabditis elegans	35.99	1.00e-49	190.00
IUUC-Cja-019016	Callithrix jacchus	55.31	7.00e-166	577.00
IUUC-Cfa-020714	Canis familiaris	58.31	0.00e+00	647.00
IUUC-Cpo-021727	Cavia porcellus	56.68	1.00e-179	622.00
IUUC-Csa-023071	Chlorocebus sabaeus	78.39	2.00e-161	561.00
IUUC-Cin-025797	Ciona intestinalis	52.02	2.00e-96	345.00
IUUC-Csv-026132	Ciona savignyi	51.15	4.00e-96	345.00
IUUC-Dre-027872	Danio rerio	80.17	3.00e-161	560.00
IUUC-Dno-029329	Dasypus novemcinctus	56.80	0.00e+00	645.00
IUUC-Dor-030574	Dipodomys ordii	56.71	0.00e+00	632.00
IUUC-Dme-032208	Drosophila melanogaster	50.30	7.00e-85	308.00
IUUC-Ete-032725	Echinops telfairi	45.58	2.00e-79	289.00
IUUC-Eca-033361	Equus caballus	58.31	0.00e+00	644.00
IUUC-Eeu-035272	Erinaceus europaeus	81.42	7.00e-85	307.00
IUUC-Fca-036497	Felis catus	57.99	0.00e+00	639.00
IUUC-Fal-036766	Ficedula albicollis	57.37	5.00e-167	580.00
IUUC-Gmo-039129	Gadus morhua	65.14	5.00e-124	437.00
IUUC-Gga-040889	Gallus gallus	77.71	2.00e-139	488.00
IUUC-Gac-042475	Gasterosteus aculeatus	69.86	2.00e-140	491.00
IUUC-Ggo-044814	Gorilla gorilla	72.19	2.00e-143	501.00
IUUC-Hsa-045937	Homo sapiens	56.68	2.00e-175	608.00
IUUC-Itr-048171	Ictidomys tridecemlineatus	57.48	0.00e+00	642.00
IUUC-Lch-050527	Latimeria chalumnae	83.28	6.00e-174	603.00
IUUC-Loc-052697	Lepisosteus oculatus	77.90	8.00e-159	553.00
IUUC-Laf-054167	Loxodonta africana	56.38	2.00e-177	615.00
IUUC-Mcc-055584	Macaca mulatta	57.49	0.00e+00	627.00
IUUC-Meu-056542	Macropus eugenii	57.60	2.00e-180	625.00
IUUC-Mga-060020	Meleagris gallopavo	56.39	9.00e-164	570.00
IUUC-Mmr-060989	Microcebus murinus	58.55	0.00e+00	640.00
IUUC-Mdo-062761	Monodelphis domestica	57.53	0.00e+00	626.00
IUUC-Mmu-063710	Mus musculus	57.23	0.00e+00	637.00
IUUC-Mpu-066573	Mustela putorius furo	57.83	0.00e+00	639.00
IUUC-Nle-070013	Nomascus leucogenys	56.16	8.00e-169	586.00
IUUC-Opr-070907	Ochotona princeps	57.23	2.00e-176	612.00
IUUC-Ont-071944	Oreochromis niloticus	81.61	5.00e-162	563.00
IUUC-Oan-073105	Ornithorhynchus anatinus	74.13	6.00e-133	466.00
IUUC-Ocu-073941	Oryctolagus cuniculus	57.88	0.00e+00	632.00
IUUC-Ola-087412	Oryzias latipes	77.21	4.00e-147	514.00
IUUC-Oga-088973	Otolemur garnettii	57.67	0.00e+00	630.00
IUUC-Oar-089916	Ovis aries	57.96	0.00e+00	630.00
IUUC-Ptr-090998	Pan troglodytes	57.17	7.00e-177	613.00
IUUC-Pan-092686	Papio anubis	57.65	0.00e+00	629.00
IUUC-Psi-093284	Pelodiscus sinensis	65.55	1.00e-113	402.00
IUUC-Pma-094462	Petromyzon marinus	68.21	3.00e-80	290.00
IUUC-Pno-094986	Phaeosphaeria nodorum	33.33	6.00e-40	159.00
IUUC-Pfo-097352	Poecilia formosa	80.34	4.00e-166	577.00
IUUC-Pab-098688	Pongo abelii	51.85	2.00e-148	518.00
IUUC-Pca-100205	Procavia capensis	76.66	4.00e-152	531.00
IUUC-Pva-103188	Pteropus vampyrus	58.32	5.00e-179	620.00
IUUC-Rno-105853	Rattus norvegicus	58.11	0.00e+00	656.00
IUUC-Sha-107237	Sarcophilus harrisii	58.23	0.00e+00	633.00
IUUC-Sar-113103	Sorex araneus	75.22	3.00e-152	530.00
IUUC-Ssc-115955	Sus scrofa	57.96	4.00e-179	620.00
IUUC-Tgu-116894	Taeniopygia guttata	62.81	9.00e-163	566.00
IUUC-Tru-117703	Takifugu rubripes	65.72	2.00e-135	475.00
IUUC-Tsy-118879	Tarsius syrichta	68.86	6.00e-174	603.00
IUUC-Tni-119866	Tetraodon nigroviridis	79.38	4.00e-155	540.00
IUUC-Tbe-127367	Tupaia belangeri	46.58	2.00e-88	319.00
IUUC-Ttr-128773	Tursiops truncatus	56.37	7.00e-177	613.00
IUUC-Vpa-130402	Vicugna pacos	81.00	9.00e-103	367.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence