iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-116725

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01010526

Gene Name

KLHL41

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000007856.1	ENSTGUT00000008183.1	ENSTGUP00000008098.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.40e-16	60.5	34	100
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	4.20e-12	45.1	133	162

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           D+ l+ g++  ++h+++L+a+S++F+  fl+e +e k k++v+++ v+p  +  ++k+lY+ ++d+n+
   Q: 34   DCSLKAGDRSLPCHRLILSACSPYFREYFLSEQNEEK-KKEVVLDNVDPNILDMIVKYLYSASIDLND 100
           9**********************************99.***************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhF 31
            Ncl+ilr++ l+dcp+L+ +a+df+++hF
   Q: 133  GNCLAILRLGVLLDCPRLAFSARDFVSDHF 162
           5***************************** PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

MDSQRELSEE LRLYQSTLLQ DGLKELLEEK KFVDCSLKAG DRSLPCHRLI LSACSPYFRE 60
YFLSEQNEEK KKEVVLDNVD PNILDMIVKY LYSASIDLND SNVQDIFALA SRFQIPSVFT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACTCCC AAAGGGAACT CTCTGAGGAG CTAAGACTTT ACCAATCCAC TCTCCTTCAG 60
GATGGCCTCA AGGAACTCCT TGAAGAGAAA AAGTTTGTAG ATTGCTCTTT AAAAGCTGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030571--KLHL41
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005856--C:cytoskeleton
GO:0005829--C:cytosol
GO:0031430--C:M band
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0033017--C:sarcoplasmic reticulum membrane
GO:0016567--P:protein ubiquitination
GO:0045661--P:regulation of myoblast differentiation
GO:2000291--P:regulation of myoblast proliferation
GO:2001014--P:regulation of skeletal muscle cell differentiation
GO:0045214--P:sarcomere organization
GO:0035914--P:skeletal muscle cell differentiation
GO:0048741--P:skeletal muscle fiber development

KEGG

tgu:100225540

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002167	Ailuropoda melanoleuca	85.81	0.00e+00	1076.00
IUUC-Apl-003866	Anas platyrhynchos	96.04	0.00e+00	1163.00
IUUC-Ame-011172	Astyanax mexicanus	61.19	0.00e+00	781.00
IUUC-Bta-012925	Bos taurus	85.48	0.00e+00	1076.00
IUUC-Bci-013875	Botrytis cinerea	28.44	2.00e-17	83.20
IUUC-Bdi-014115	Brachypodium distachyon	25.95	5.00e-13	68.60
IUUC-Cja-019348	Callithrix jacchus	85.31	0.00e+00	1074.00
IUUC-Cfa-020782	Canis familiaris	85.81	0.00e+00	1076.00
IUUC-Cpo-021825	Cavia porcellus	83.50	0.00e+00	1051.00
IUUC-Csa-023184	Chlorocebus sabaeus	85.99	0.00e+00	922.00
IUUC-Dre-028278	Danio rerio	62.09	0.00e+00	807.00
IUUC-Dno-029516	Dasypus novemcinctus	85.15	0.00e+00	1071.00
IUUC-Dor-030850	Dipodomys ordii	81.41	0.00e+00	691.00
IUUC-Ete-032697	Echinops telfairi	84.82	0.00e+00	1052.00
IUUC-Eca-033714	Equus caballus	85.64	0.00e+00	1075.00
IUUC-Eeu-035245	Erinaceus europaeus	84.71	0.00e+00	995.00
IUUC-Gmo-039392	Gadus morhua	59.11	0.00e+00	769.00
IUUC-Ggr-040041	Gaeumannomyces graminis	27.08	3.00e-07	48.90
IUUC-Gga-041106	Gallus gallus	96.86	0.00e+00	1185.00
IUUC-Gac-042252	Gasterosteus aculeatus	59.87	0.00e+00	789.00
IUUC-Ggo-044817	Gorilla gorilla	85.81	0.00e+00	1077.00
IUUC-Hsa-046620	Homo sapiens	85.81	0.00e+00	1076.00
IUUC-Lch-050477	Latimeria chalumnae	68.86	0.00e+00	872.00
IUUC-Loc-051955	Lepisosteus oculatus	71.95	0.00e+00	934.00
IUUC-Laf-053500	Loxodonta africana	85.81	0.00e+00	1076.00
IUUC-Mcc-055316	Macaca mulatta	85.64	0.00e+00	1075.00
IUUC-Mor-057181	Magnaporthe oryzae	27.22	7.00e-11	61.20
IUUC-Mmr-061444	Microcebus murinus	85.48	0.00e+00	1073.00
IUUC-Mmu-064147	Mus musculus	85.31	0.00e+00	1073.00
IUUC-Mlu-067481	Myotis lucifugus	83.50	0.00e+00	1054.00
IUUC-Ncr-068938	Neurospora crassa	28.89	6.00e-07	48.90
IUUC-Nle-069339	Nomascus leucogenys	85.81	0.00e+00	1075.00
IUUC-Opr-070703	Ochotona princeps	85.31	0.00e+00	1030.00
IUUC-Ont-072420	Oreochromis niloticus	60.63	0.00e+00	822.00
IUUC-Oan-073476	Ornithorhynchus anatinus	84.82	0.00e+00	1075.00
IUUC-Ocu-074248	Oryctolagus cuniculus	85.31	0.00e+00	1077.00
IUUC-Ola-086361	Oryzias latipes	61.67	0.00e+00	803.00
IUUC-Oar-090349	Ovis aries	85.31	0.00e+00	1072.00
IUUC-Pan-092069	Papio anubis	85.81	0.00e+00	1077.00
IUUC-Psi-093671	Pelodiscus sinensis	89.93	0.00e+00	1089.00
IUUC-Pfo-096122	Poecilia formosa	63.12	0.00e+00	837.00
IUUC-Pab-098711	Pongo abelii	85.64	0.00e+00	1075.00
IUUC-Pca-100495	Procavia capensis	78.71	0.00e+00	965.00
IUUC-Pva-102401	Pteropus vampyrus	85.64	0.00e+00	1074.00
IUUC-Rno-105969	Rattus norvegicus	85.31	0.00e+00	1073.00
IUUC-Sar-113405	Sorex araneus	83.83	0.00e+00	1044.00
IUUC-Tru-117743	Takifugu rubripes	58.87	0.00e+00	788.00
IUUC-Tsy-119225	Tarsius syrichta	79.37	0.00e+00	981.00
IUUC-Tni-120547	Tetraodon nigroviridis	61.13	0.00e+00	811.00
IUUC-Ttr-128645	Tursiops truncatus	85.31	0.00e+00	1073.00
IUUC-Vpa-130714	Vicugna pacos	85.31	0.00e+00	1075.00
IUUC-Xtr-132144	Xenopus tropicalis	75.25	0.00e+00	953.00
IUUC-Xma-133860	Xiphophorus maculatus	63.12	0.00e+00	840.00
IUUC-Yli-134535	Yarrowia lipolytica	23.56	4.00e-07	48.50

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence