iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ssc-115533

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

CU459043

Gene Name

USP20

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000024341.1	ENSSSCT00000023659.1	ENSSSCP00000021383.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.60e-108	363.1	154	688

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgye 88
           tG+kNlgN+CYmN++LQ+Lsn+p+l++++le     +    ++++k +l+ks+qkl++e+w  ++ ++v p++l + +k ++++f+gy+
   Q: 154  TGMKNLGNSCYMNAALQALSNCPPLTQFFLE-----CGGLVRTDKKPALCKSYQKLVTEVWhRKRPSYVVPTSLSHGIKLVNPMFRGYA 237
           7******************************.....999999*******************889999********************** PP
   S: 89   qqDaqEflaflldqleeelkk............eknkpkeeeeeedkselsde.................................... 129
           qqD+qEfl++l+dql+eelk+            +++++ +e           +                                    
   Q: 238  QQDTQEFLRCLMDQLHEELKEprvaaalpeardSDSSDSDE-----------Kregdrspsedeflscdsssdrgegdgqgrggggspa 315
           *******************9975555555554444444444...........344555555556************************* PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 316  etellipdeagraisekerrkdrrfswgqqrtsseqvdedadvdtamaaldqqptdtqppsprstkpdneahmrsasrpcspvhhhegh 404
           ***************************************************************************************** PP
   S: 130  ..............................aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke... 185
                                         ++++k+++++s+isd+F+g++ s ++cl+cd+vs++ e+f+dlslp+pgke+ +k+   
   Q: 405  aklagsppraspvrmgpsyvlkkaqvpstgSRRRKEQQYRSVISDIFDGSILSLVQCLTCDRVSTTVETFQDLSLPIPGKEDLAKLhsa 493
           *********************************************************************************99888*** PP
   S: 186  ..............................................slqdcLesftkeeele..genkyycekckkkqeaekklklkkl 226
                                                         +l+dcL++f++++el+  g+n+y+ce+ckk+++ +k +k+ +l
   Q: 494  iyqnvpakpgacgdsyaaqgwlafiveyirrfvvsctpswfwgpvvTLEDCLAAFFAADELKapGDNMYSCERCKKLRNGVKYCKVLQL 582
           *************************************************************86679*********************** PP
   S: 227  PevLilhLkRfsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDsk 313
           Pe+L++hLkRf  ++e + + ki+++v+fple Ldl+pf+++++++q   ++Y+L++v++H+G+++sGHY+ay++n  +g+W++fdD++
   Q: 583  PEILCIHLKRF--RHEVMYSFKISSHVSFPLEgLDLRPFLAKECTSQ--ITTYDLLSVICHHGTAGSGHYIAYCQNvINGQWYEFDDQY 667
           ***********..9999***************************999..9**************************78999******** PP
   S: 314  VtevkeeevleetgstaYvlfYkr 337
           Vtev+e+ v++   ++aYvlfY++
   Q: 668  VTEVHETLVQN---AEAYVLFYRK 688
           ***********...********98 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MGDSRDPCPH LDSIGEVTKE DLLLKSKGTC QSCGVAGPNL WACLQVSCSY VGCGESFADH 60
STIHAQVKTH NLTVNLTTFR VWCYACEKEV FLEQRLAAHP PGPSPKFSEQ VALRSSCQDS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGGGCGCGG CCGGCAGGGC CTCACGACCC TGCGCCGTGC CGCGGAGGGC GCGCTTGACT 60
GACAGGCGGC GGTGGCGCGG TTGCGACGGC AGGTGAGTTC CGGGCCGCCG CCGGCTGCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF06337--DUSP
PF00443--UCH
PF02148--zf-UBP

SMART

SM00695--DUSP
SM00290--ZnF_UBP

Gene Ontology

GO:0005813--C:centrosome
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination
GO:0008277--P:regulation of G-protein coupled receptor protein signaling pathway
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002209	Ailuropoda melanoleuca	91.47	0.00e+00	1634.00
IUUC-Apl-003351	Anas platyrhynchos	83.85	0.00e+00	1531.00
IUUC-Aca-005077	Anolis carolinensis	75.07	0.00e+00	1095.00
IUUC-Ame-011777	Astyanax mexicanus	74.63	0.00e+00	1326.00
IUUC-Bta-013063	Bos taurus	93.20	0.00e+00	1648.00
IUUC-Cja-019868	Callithrix jacchus	91.25	0.00e+00	1655.00
IUUC-Cfa-020761	Canis familiaris	92.12	0.00e+00	1656.00
IUUC-Cpo-022267	Cavia porcellus	83.62	0.00e+00	1504.00
IUUC-Csa-024251	Chlorocebus sabaeus	92.11	0.00e+00	1668.00
IUUC-Cho-024483	Choloepus hoffmanni	96.23	3.00e-124	439.00
IUUC-Csv-025889	Ciona savignyi	43.75	2.00e-35	141.00
IUUC-Dre-028061	Danio rerio	73.36	0.00e+00	1195.00
IUUC-Dno-029423	Dasypus novemcinctus	92.32	0.00e+00	1674.00
IUUC-Dor-030877	Dipodomys ordii	89.87	0.00e+00	1077.00
IUUC-Dme-031837	Drosophila melanogaster	49.67	1.00e-136	480.00
IUUC-Ete-032802	Echinops telfairi	78.21	2.00e-130	459.00
IUUC-Eca-034283	Equus caballus	92.33	0.00e+00	1659.00
IUUC-Eeu-034620	Erinaceus europaeus	89.21	0.00e+00	1170.00
IUUC-Fca-036357	Felis catus	92.87	0.00e+00	1648.00
IUUC-Fal-037411	Ficedula albicollis	84.27	0.00e+00	1529.00
IUUC-Gga-041101	Gallus gallus	83.77	0.00e+00	1508.00
IUUC-Gac-041315	Gasterosteus aculeatus	72.98	0.00e+00	1299.00
IUUC-Ggo-045600	Gorilla gorilla	91.81	0.00e+00	1636.00
IUUC-Hsa-045825	Homo sapiens	92.22	0.00e+00	1642.00
IUUC-Itr-048549	Ictidomys tridecemlineatus	79.13	0.00e+00	1358.00
IUUC-Lch-050002	Latimeria chalumnae	74.41	0.00e+00	1296.00
IUUC-Loc-052574	Lepisosteus oculatus	76.33	0.00e+00	1391.00
IUUC-Laf-054428	Loxodonta africana	91.27	0.00e+00	1635.00
IUUC-Mcc-055736	Macaca mulatta	91.78	0.00e+00	1665.00
IUUC-Mga-059781	Meleagris gallopavo	84.09	0.00e+00	1514.00
IUUC-Mdo-063048	Monodelphis domestica	84.77	0.00e+00	1512.00
IUUC-Mmu-064079	Mus musculus	90.29	0.00e+00	1622.00
IUUC-Mpu-066616	Mustela putorius furo	91.27	0.00e+00	1678.00
IUUC-Mlu-067294	Myotis lucifugus	91.25	0.00e+00	1571.00
IUUC-Nle-070015	Nomascus leucogenys	92.00	0.00e+00	1611.00
IUUC-Opr-070328	Ochotona princeps	91.04	0.00e+00	1645.00
IUUC-Ont-071464	Oreochromis niloticus	74.54	0.00e+00	1301.00
IUUC-Oan-073259	Ornithorhynchus anatinus	78.22	0.00e+00	1312.00
IUUC-Ocu-074630	Oryctolagus cuniculus	88.23	0.00e+00	1546.00
IUUC-Ola-087240	Oryzias latipes	73.19	0.00e+00	1288.00
IUUC-Oga-088761	Otolemur garnettii	90.59	0.00e+00	1640.00
IUUC-Oar-089490	Ovis aries	87.45	0.00e+00	1498.00
IUUC-Ptr-091662	Pan troglodytes	92.11	0.00e+00	1638.00
IUUC-Pan-092199	Papio anubis	92.00	0.00e+00	1664.00
IUUC-Psi-093726	Pelodiscus sinensis	84.77	0.00e+00	1535.00
IUUC-Pma-094389	Petromyzon marinus	62.79	5.00e-101	360.00
IUUC-Pab-098632	Pongo abelii	91.78	0.00e+00	1628.00
IUUC-Pca-100614	Procavia capensis	84.39	0.00e+00	1252.00
IUUC-Pva-102922	Pteropus vampyrus	89.02	0.00e+00	956.00
IUUC-Rno-105215	Rattus norvegicus	90.28	0.00e+00	1626.00
IUUC-Sha-106601	Sarcophilus harrisii	85.19	0.00e+00	1506.00
IUUC-Tgu-117364	Taeniopygia guttata	84.29	0.00e+00	1510.00
IUUC-Tru-117770	Takifugu rubripes	71.93	0.00e+00	1287.00
IUUC-Tni-120001	Tetraodon nigroviridis	72.70	0.00e+00	1256.00
IUUC-Ttr-128732	Tursiops truncatus	93.84	0.00e+00	1661.00
IUUC-Xtr-132157	Xenopus tropicalis	75.57	0.00e+00	1344.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence