iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gga-041196

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AADN04000032

Gene Name

USP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000010957.6	ENSGALT00000017833.6	ENSGALP00000017812.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.00e-85	288.3	82	791

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle......kkkeklneenpkepkg...........ellkslqklfeel.......w.... 61
           +Gl+NlgNtCY+NSvLQ+L+++p ++  +++      kkke+l++e + + ++           el++sl++l+ ++       +    
   Q: 82   VGLNNLGNTCYLNSVLQVLYFCPGFKTGVKHlyniisKKKESLKDEGELKAEKgnckedplasyELICSLHSLILSVeqlqasfLlnpe 170
           6******************************7777776666666665544444788888888998888888888877554444425555 PP
   S: 62   .kskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkk...................eknkpkeeeeeedkselsde. 129
            ++++ a++pr+ll++l++++++++gy q+DaqE+l+++l +++e+++                    e                  + 
   Q: 171  kYTDELATQPRRLLNTLRELNPMYEGYLQHDAQEVLQCILGNIQETCQLlkkeelnklpleepkakveE------------------Ki 241
           588888*****************************************5555555555544433333332..................13 PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 242  npnsesngtgnsaeeeeenapsshvgevaedklpkgngkrksdaeggnakkkskvskeqiaaeenqrqtrskrkatgeklenqsdaiak 330
           33444556666777777999999****************************************************************** PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 331  cstenesakptqkksrlklnwlkssckqpsilskfyslgklstnlgskdpeyddceleessakcengndikeedghepaspveshtekg 419
           ***********************************************************************************999987 PP
   S: 130  .....aeekkkkknk.....slisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke..............slqdcLesf 194
                ++e      +     +l+++lFqgql  +++clec+  ++r+e+f+d+s+pv+++e +k+e              +l++++++f
   Q: 420  tekepKKEG-----TelavfELVEKLFQGQLVLRTRCLECECFTERREDFQDISVPVQEDELSKTEesseispepktemkTLKWAISQF 503
           644433333.....245666*****************************************998889********************** PP
   S: 195  tkeeelegenkyycekckkkqeaekklklkklPevLilhLkRf.....sfseeqksrekinkkvefpleLdlspfctspeekqkekkkY 278
           ++ e++ ge+ky+ce+c++++eae++l ++k+Pev+++hLk+f     +f+++++  +kin+ + +pl+L+l+++ t+p+     +++Y
   Q: 504  ASVERIVGEDKYFCENCHHYTEAERSLLFDKMPEVITIHLKCFaasglEFDCYGGL-SKINTPLLTPLKLSLEEWSTKPT-----NDTY 586
           ****************************************************9555.6********************98.....789* PP
   S: 279  eLiavvvHsG.slssGHYvayvkn................................................................. 301
            L+avv+HsG ++ssGHY+a vk                                                                  
   Q: 587  GLFAVVMHSGiTISSGHYTASVKItdlnsleldkgnfitaqmcetikpeplneeeartaaedyddgevsfrvngnaqpgkvlnkknmea 675
           ***************************************************************************************** PP
   S: 302  ..........................................................................ekgkWllfdDskVte 316
                                                                                      +gkWllfdDs+V++
   Q: 676  vgllggqksksdcdlyskpassekvlsivtenrnpesapangsvecstergdqngvafsglenkalyvlqslkeYEGKWLLFDDSEVKV 764
           ****************************************99999999999999999999998888888887766999*********** PP
   S: 317  vkeeevleetg......staYvlfYkr 337
           ++e+++l++ +      st+Y+lfYk+
   Q: 765  TEEKDFLNSLSptssstSTPYLLFYKK 791
           ********888**************97 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MPGVLPSDGS APPRGSPSRK NRLSLKLFQK KEAKRALDFT EPPENEQKGA ELRGAEIDQV 60
VPAAQPPSLV SCEKKDNMLP FVGLNNLGNT CYLNSVLQVL YFCPGFKTGV KHLYNIISKK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGTTAGCGGC GCCCGCGCGC GCACGGGTAG GACCCTGCGG GCTGCCCGCC GCGCTGCCTG 60
ACGGGAGCGG CGGACGCGCG GCGCCGATGC CGCCGATCGG GCCCGCGCCG AGGTCTCTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033815--USP1
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0006282--P:regulation of DNA repair
GO:0009411--P:response to UV
GO:0001501--P:skeletal system development
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001939	Ailuropoda melanoleuca	73.19	0.00e+00	1087.00
IUUC-Apl-004204	Anas platyrhynchos	93.23	0.00e+00	1219.00
IUUC-Aca-004637	Anolis carolinensis	72.27	0.00e+00	1032.00
IUUC-Ame-011718	Astyanax mexicanus	50.89	2.00e-180	625.00
IUUC-Bta-012552	Bos taurus	71.48	0.00e+00	1073.00
IUUC-Cja-019588	Callithrix jacchus	72.91	0.00e+00	1089.00
IUUC-Cfa-020211	Canis familiaris	73.91	0.00e+00	1105.00
IUUC-Cpo-021551	Cavia porcellus	68.97	0.00e+00	1010.00
IUUC-Csa-024186	Chlorocebus sabaeus	73.25	0.00e+00	1091.00
IUUC-Cho-024739	Choloepus hoffmanni	63.24	5.00e-154	537.00
IUUC-Dre-028184	Danio rerio	48.20	1.00e-175	609.00
IUUC-Dno-029669	Dasypus novemcinctus	71.91	0.00e+00	1080.00
IUUC-Dor-030168	Dipodomys ordii	68.83	0.00e+00	959.00
IUUC-Dme-031732	Drosophila melanogaster	29.38	3.00e-18	87.80
IUUC-Ete-032825	Echinops telfairi	69.61	0.00e+00	718.00
IUUC-Eca-033595	Equus caballus	72.40	0.00e+00	997.00
IUUC-Eeu-034877	Erinaceus europaeus	71.12	4.00e-120	425.00
IUUC-Fca-035381	Felis catus	71.45	0.00e+00	753.00
IUUC-Fal-037592	Ficedula albicollis	84.19	0.00e+00	1196.00
IUUC-Gmo-039680	Gadus morhua	46.40	1.00e-162	566.00
IUUC-Gac-042292	Gasterosteus aculeatus	47.99	6.00e-143	501.00
IUUC-Ggo-044671	Gorilla gorilla	73.03	0.00e+00	1092.00
IUUC-Hsa-047020	Homo sapiens	72.81	0.00e+00	1092.00
IUUC-Itr-048800	Ictidomys tridecemlineatus	65.76	0.00e+00	946.00
IUUC-Lch-050543	Latimeria chalumnae	60.18	0.00e+00	731.00
IUUC-Loc-052338	Lepisosteus oculatus	53.68	0.00e+00	717.00
IUUC-Laf-053707	Loxodonta africana	71.87	0.00e+00	1082.00
IUUC-Mcc-055885	Macaca mulatta	73.00	0.00e+00	1092.00
IUUC-Meu-056573	Macropus eugenii	62.70	0.00e+00	879.00
IUUC-Mga-059346	Meleagris gallopavo	96.31	0.00e+00	1368.00
IUUC-Mmr-061612	Microcebus murinus	71.55	0.00e+00	1065.00
IUUC-Mdo-062887	Monodelphis domestica	69.23	0.00e+00	982.00
IUUC-Mmu-064044	Mus musculus	72.09	0.00e+00	1072.00
IUUC-Mpu-066847	Mustela putorius furo	73.53	0.00e+00	1102.00
IUUC-Mlu-067684	Myotis lucifugus	73.50	0.00e+00	1092.00
IUUC-Nle-070057	Nomascus leucogenys	72.98	0.00e+00	1097.00
IUUC-Opr-070463	Ochotona princeps	66.21	0.00e+00	934.00
IUUC-Ont-071975	Oreochromis niloticus	45.60	8.00e-156	543.00
IUUC-Oan-073062	Ornithorhynchus anatinus	73.74	6.00e-39	152.00
IUUC-Ocu-074840	Oryctolagus cuniculus	71.75	0.00e+00	1082.00
IUUC-Ola-087088	Oryzias latipes	47.42	4.00e-170	591.00
IUUC-Oga-088472	Otolemur garnettii	72.66	0.00e+00	1073.00
IUUC-Oar-089498	Ovis aries	72.50	0.00e+00	1080.00
IUUC-Ptr-091395	Pan troglodytes	72.81	0.00e+00	1092.00
IUUC-Pan-092462	Papio anubis	73.12	0.00e+00	1093.00
IUUC-Psi-093583	Pelodiscus sinensis	81.78	0.00e+00	1041.00
IUUC-Pma-094644	Petromyzon marinus	38.68	2.00e-27	115.00
IUUC-Pfo-096314	Poecilia formosa	47.68	2.00e-166	579.00
IUUC-Pab-098568	Pongo abelii	73.16	0.00e+00	1094.00
IUUC-Pca-100948	Procavia capensis	68.64	6.00e-149	521.00
IUUC-Pva-102853	Pteropus vampyrus	72.40	0.00e+00	1076.00
IUUC-Rno-105573	Rattus norvegicus	73.18	0.00e+00	1090.00
IUUC-Sha-107495	Sarcophilus harrisii	68.12	0.00e+00	830.00
IUUC-Sar-113545	Sorex araneus	61.40	0.00e+00	823.00
IUUC-Ssc-115962	Sus scrofa	72.35	0.00e+00	1074.00
IUUC-Tgu-116731	Taeniopygia guttata	84.15	0.00e+00	1207.00
IUUC-Tru-117893	Takifugu rubripes	46.25	9.00e-152	530.00
IUUC-Tsy-119644	Tarsius syrichta	66.33	3.00e-139	489.00
IUUC-Tni-119819	Tetraodon nigroviridis	45.69	9.00e-168	583.00
IUUC-Tbe-127272	Tupaia belangeri	69.25	0.00e+00	917.00
IUUC-Ttr-128404	Tursiops truncatus	72.59	0.00e+00	1075.00
IUUC-Vpa-130205	Vicugna pacos	72.31	0.00e+00	1078.00
IUUC-Xtr-132613	Xenopus tropicalis	56.45	0.00e+00	737.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence