iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-072266

Ensembl Protein ID

ENSONIP00000019292.1

UniProt Accession

I3KDU7; I3KDU7_ORENI

Genbank Protein ID

ENSONIP00000019292

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AERX01038008

Gene Name

blk

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000015333.1	ENSONIT00000019309.1	ENSONIP00000019292.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.40e-15	57.4	44	101

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +  +++++d++a+nd +L ++kGd+++v+   ++ ++W+ +   ++g++Gl+P+n+v++++
   Q: 44   DTIFIAQHDFKATNDSDLPFRKGDKLKVL---QETGEWWLARLLTTGQEGLIPSNYVARAD 101
           67899************************...88899********************9986 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MGCTCSGEKQ VKEEGFYKGK HKSHASPSSN HIGRSGNAYT NNDDTIFIAQ HDFKATNDSD 60
LPFRKGDKLK VLQETGEWWL ARLLTTGQEG LIPSNYVARA DTLEVEKWFF KDLGRRETER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AATTAGAGCA GAGCAAAAGA GAGAGAGAAA CTTTCCAAAC CAAAATGAGT GAGTGAGAGT 60
GACACACTGA CAAGCACTCA GTTTTCAATG AGGAAATTGA AGACATTTTG CATCTGGAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002133	Ailuropoda melanoleuca	68.83	0.00e+00	679.00
IUUC-Apl-003307	Anas platyrhynchos	70.69	0.00e+00	695.00
IUUC-Aca-004357	Anolis carolinensis	67.19	0.00e+00	639.00
IUUC-Ame-010642	Astyanax mexicanus	78.32	0.00e+00	813.00
IUUC-Bta-012400	Bos taurus	71.05	0.00e+00	685.00
IUUC-Cfa-021056	Canis familiaris	68.61	0.00e+00	676.00
IUUC-Cpo-021779	Cavia porcellus	71.33	0.00e+00	696.00
IUUC-Csa-023557	Chlorocebus sabaeus	67.89	0.00e+00	674.00
IUUC-Dre-027517	Danio rerio	75.66	0.00e+00	798.00
IUUC-Eca-034218	Equus caballus	68.18	0.00e+00	672.00
IUUC-Eeu-035095	Erinaceus europaeus	53.56	6.00e-139	487.00
IUUC-Fca-036015	Felis catus	65.33	0.00e+00	677.00
IUUC-Fal-036946	Ficedula albicollis	69.68	0.00e+00	678.00
IUUC-Gmo-038861	Gadus morhua	80.18	0.00e+00	747.00
IUUC-Gga-040822	Gallus gallus	70.42	0.00e+00	699.00
IUUC-Gac-041860	Gasterosteus aculeatus	80.82	0.00e+00	832.00
IUUC-Hsa-046719	Homo sapiens	69.16	0.00e+00	676.00
IUUC-Itr-048323	Ictidomys tridecemlineatus	70.88	0.00e+00	674.00
IUUC-Lch-050114	Latimeria chalumnae	72.04	0.00e+00	699.00
IUUC-Loc-052326	Lepisosteus oculatus	74.00	0.00e+00	776.00
IUUC-Laf-053387	Loxodonta africana	64.47	0.00e+00	671.00
IUUC-Mcc-055026	Macaca mulatta	69.03	0.00e+00	676.00
IUUC-Mga-059427	Meleagris gallopavo	70.31	0.00e+00	686.00
IUUC-Mmr-061660	Microcebus murinus	66.40	0.00e+00	685.00
IUUC-Mdo-062318	Monodelphis domestica	70.81	0.00e+00	674.00
IUUC-Mmu-063325	Mus musculus	65.93	0.00e+00	679.00
IUUC-Mpu-066582	Mustela putorius furo	68.83	0.00e+00	682.00
IUUC-Nle-069624	Nomascus leucogenys	70.43	0.00e+00	676.00
IUUC-Ocu-073907	Oryctolagus cuniculus	65.55	0.00e+00	688.00
IUUC-Ola-086668	Oryzias latipes	84.72	0.00e+00	809.00
IUUC-Oga-088057	Otolemur garnettii	64.73	0.00e+00	674.00
IUUC-Ptr-091551	Pan troglodytes	68.82	0.00e+00	641.00
IUUC-Psi-093895	Pelodiscus sinensis	71.59	0.00e+00	699.00
IUUC-Pfo-096608	Poecilia formosa	85.10	0.00e+00	882.00
IUUC-Pab-097598	Pongo abelii	70.43	0.00e+00	674.00
IUUC-Pva-102135	Pteropus vampyrus	69.78	0.00e+00	678.00
IUUC-Rno-104891	Rattus norvegicus	69.30	0.00e+00	681.00
IUUC-Sha-107192	Sarcophilus harrisii	71.23	0.00e+00	675.00
IUUC-Ssc-115696	Sus scrofa	65.87	0.00e+00	686.00
IUUC-Tgu-117056	Taeniopygia guttata	69.46	0.00e+00	677.00
IUUC-Tru-117621	Takifugu rubripes	79.02	0.00e+00	820.00
IUUC-Ttr-128457	Tursiops truncatus	65.40	0.00e+00	678.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence