iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000008452.5	ENSGALT00000013770.5	ENSGALP00000013755.5
ENSGALG00000008452.5	ENSGALT00000073565.1	ENSGALP00000055092.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-15	57.5	51	80

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvW 28
           gH+d v+c+a+  d ++++sGs D+++ +W
   Q: 51   GHKDTVYCVAYaKDgKRFASGSADKSVIIW 80
           8***********777*************** PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MRAALTWRDR AEHCIYDLAF KPDGTQLIIA AGNRLLVYDT SDGTLIQPLK GHKDTVYCVA 60
YAKDGKRFAS GSADKSVIIW TSKLEGILKY THNDSIQCVS YNPLTHQLAS CSSSDFGLWS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCGGGCCG CGCTCACCTG GCGCGACAGG GCCGAGCACT GGTGAGCGCC GCGGGGCCGG 60
CGGGGGCGGC AGGGAGCGCC GGGCCGGCAG CGTGCGCGGG GCCGGGCTCG GGCGGCCCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0036064--C:ciliary basal body
GO:0097546--C:ciliary base
GO:0005929--C:cilium
GO:0005829--C:cytosol
GO:0030991--C:intraciliary transport particle A
GO:0016020--C:membrane
GO:0005654--C:nucleoplasm
GO:0032391--C:photoreceptor connecting cilium
GO:0048593--P:camera-type eye morphogenesis
GO:0060830--P:ciliary receptor clustering involved in smoothened signaling pathway
GO:0060271--P:cilium assembly
GO:0010172--P:embryonic body morphogenesis
GO:0042733--P:embryonic digit morphogenesis
GO:0035115--P:embryonic forelimb morphogenesis
GO:0060971--P:embryonic heart tube left/right pattern formation
GO:0072594--P:establishment of protein localization to organelle
GO:0035720--P:intraciliary anterograde transport
GO:0035721--P:intraciliary retrograde transport
GO:0050680--P:negative regulation of epithelial cell proliferation
GO:0021914--P:negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
GO:0001843--P:neural tube closure
GO:1905515--P:non-motile cilium assembly
GO:0061512--P:protein localization to cilium
GO:0007227--P:signal transduction downstream of smoothened
GO:0060831--P:smoothened signaling pathway involved in dorsal/ventral neural tube patterning

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001933	Ailuropoda melanoleuca	89.01	0.00e+00	1795.00
IUUC-Apl-003504	Anas platyrhynchos	96.33	0.00e+00	2335.00
IUUC-Aca-004767	Anolis carolinensis	84.09	0.00e+00	2159.00
IUUC-Ame-011642	Astyanax mexicanus	67.36	0.00e+00	1677.00
IUUC-Bta-012969	Bos taurus	87.86	0.00e+00	1782.00
IUUC-Cel-018670	Caenorhabditis elegans	39.11	0.00e+00	912.00
IUUC-Cja-019249	Callithrix jacchus	80.30	0.00e+00	1605.00
IUUC-Cfa-020915	Canis familiaris	88.83	0.00e+00	1797.00
IUUC-Cpo-021888	Cavia porcellus	86.11	0.00e+00	2138.00
IUUC-Cre-022789	Chlamydomonas reinhardtii	52.35	0.00e+00	1187.00
IUUC-Csa-023533	Chlorocebus sabaeus	85.40	0.00e+00	1719.00
IUUC-Cin-025121	Ciona intestinalis	61.03	0.00e+00	1563.00
IUUC-Csv-026240	Ciona savignyi	59.43	0.00e+00	1452.00
IUUC-Dno-029685	Dasypus novemcinctus	88.91	0.00e+00	2140.00
IUUC-Dme-032005	Drosophila melanogaster	22.51	2.00e-09	58.50
IUUC-Ete-032682	Echinops telfairi	78.69	0.00e+00	1578.00
IUUC-Eca-033831	Equus caballus	84.44	0.00e+00	2138.00
IUUC-Eeu-034919	Erinaceus europaeus	80.45	0.00e+00	952.00
IUUC-Fca-036559	Felis catus	76.06	0.00e+00	1858.00
IUUC-Fal-037340	Ficedula albicollis	91.05	0.00e+00	2227.00
IUUC-Ggo-045356	Gorilla gorilla	84.99	0.00e+00	1711.00
IUUC-Hsa-046135	Homo sapiens	84.99	0.00e+00	1711.00
IUUC-Itr-048228	Ictidomys tridecemlineatus	73.70	0.00e+00	1802.00
IUUC-Lch-050183	Latimeria chalumnae	84.55	0.00e+00	1211.00
IUUC-Loc-052049	Lepisosteus oculatus	85.38	0.00e+00	2118.00
IUUC-Laf-053728	Loxodonta africana	76.11	0.00e+00	1877.00
IUUC-Mcc-054971	Macaca mulatta	85.40	0.00e+00	1722.00
IUUC-Meu-056446	Macropus eugenii	78.21	0.00e+00	2026.00
IUUC-Mga-059296	Meleagris gallopavo	97.39	0.00e+00	1990.00
IUUC-Mmr-061232	Microcebus murinus	80.68	0.00e+00	2030.00
IUUC-Mdo-062115	Monodelphis domestica	85.36	0.00e+00	2172.00
IUUC-Mmu-063664	Mus musculus	83.56	0.00e+00	2115.00
IUUC-Mpu-066136	Mustela putorius furo	84.61	0.00e+00	1727.00
IUUC-Mlu-068238	Myotis lucifugus	86.66	0.00e+00	1797.00
IUUC-Nle-069003	Nomascus leucogenys	80.80	0.00e+00	1617.00
IUUC-Ont-072080	Oreochromis niloticus	68.53	0.00e+00	1706.00
IUUC-Oan-072891	Ornithorhynchus anatinus	91.50	0.00e+00	958.00
IUUC-Ocu-074262	Oryctolagus cuniculus	74.62	0.00e+00	1811.00
IUUC-Ola-086538	Oryzias latipes	76.81	0.00e+00	1571.00
IUUC-Oga-088722	Otolemur garnettii	88.22	0.00e+00	1761.00
IUUC-Oar-089249	Ovis aries	88.08	0.00e+00	2125.00
IUUC-Ptr-090752	Pan troglodytes	85.10	0.00e+00	1711.00
IUUC-Pan-092472	Papio anubis	81.87	0.00e+00	2016.00
IUUC-Psi-093335	Pelodiscus sinensis	92.65	0.00e+00	2278.00
IUUC-Pma-094520	Petromyzon marinus	71.74	0.00e+00	1666.00
IUUC-Ppa-095600	Physcomitrella patens	61.06	7.00e-39	152.00
IUUC-Pfo-096526	Poecilia formosa	70.25	0.00e+00	1763.00
IUUC-Pab-098428	Pongo abelii	81.25	0.00e+00	996.00
IUUC-Pca-100233	Procavia capensis	84.03	0.00e+00	748.00
IUUC-Pva-103064	Pteropus vampyrus	71.87	0.00e+00	1768.00
IUUC-Rno-105764	Rattus norvegicus	75.98	0.00e+00	1856.00
IUUC-Sha-106649	Sarcophilus harrisii	85.23	0.00e+00	2164.00
IUUC-Smo-109478	Selaginella moellendorffii	42.87	0.00e+00	959.00
IUUC-Tgu-116870	Taeniopygia guttata	87.36	0.00e+00	2139.00
IUUC-Tru-118661	Takifugu rubripes	71.30	0.00e+00	1827.00
IUUC-Tsy-119640	Tarsius syrichta	69.52	7.00e-175	608.00
IUUC-Tni-120812	Tetraodon nigroviridis	68.53	0.00e+00	1686.00
IUUC-Ttr-128862	Tursiops truncatus	87.21	0.00e+00	1796.00
IUUC-Vpa-130049	Vicugna pacos	72.73	5.00e-141	495.00
IUUC-Xtr-131914	Xenopus tropicalis	82.58	0.00e+00	2025.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence