iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062078

UUCD1 version

UUC-MoD-00956

Ensembl Protein ID

ENSMODP00000026640.2

UniProt Accession

F7G392; F7G392_MONDO

Protein Name

Uncharacterized protein

Gene Name

TBL1XR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000021312.2	ENSMODT00000027116.2	ENSMODP00000026640.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-53	176.8	348	386
UBD/Beta-Prp	6.30e-66	222.7	311	514

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHt++v+++++ ++ +ll+s+sdD t+k+W++++  +++
   Q: 348  GHTNEVNAIKWdPTgNLLASCSDDMTLKIWSMKQESCVH 386
           8***********778*****************9999986 PP

UBD/Beta-Prp

   S: 12   vitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlsl 100
           +  +v++ ++++ +a+ s+d +i v ++ +   +++++gh++ev+a+k++p+g++l+++s+D+t+k+w++++ +cvh l++h+++++++
   Q: 311  PALDVDW-QSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQESCVHDLQAHNKEIYTI 398
           4445555.677778888888888888888877788888888888888888888888888888888888888888888888888888888 PP
   S: 101  sfsp........sg.dklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgght 180
           ++sp        +    l+s+s d+t+r+wd++ g c++ tl++h++ v +v+++pdg++l+sGs D++v +W+ +tg l++  +g  t
   Q: 399  KWSPtgpgtnnpNAnLMLASASFDSTVRLWDVDRGICIH-TLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRG--T 484
           887766555444222467788888888888888888887.8888888888888888888888888888888888888888888877..7 PP
   S: 181  dsvyslsfdsngkelvsgsldgtvklwdlq 210
           + +  + ++  g  + + + dg+v + dl+
   Q: 485  GGIFEVCWNAAGDKVGASASDGSVCVLDLR 514
           788888888888888888888877777765 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MSISSDEVNF LVYRYLQESG FSHSAFTFGI ESHISQSNIN GALVPPAALI SIIQKGLQYV 60
EAEVSINEDG TLFDGRPIES LSLIDAVMPD VVQTRQQAYR DKLAQQQAAA AAATAAATTN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGTTATATC CTGTGTTGTG ACCTCATGGT TTAAGTGGGA ATAAAGATGA GTATAAGCAG 60
TGATGAGGTC AACTTCTTGG TATATAGATA CTTGCAAGAG TCAGGTGAGT ACTTGTATAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR006594--LisH
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08513--LisH
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00667--LisH
SM00320--WD40

Gene Ontology

GO:0000118--C:histone deacetylase complex
GO:0003714--F:transcription corepressor activity
GO:0016575--P:histone deacetylation
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

KEGG

mdo:100619476

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000916	Aegilops tauschii	60.00	2.00e-54	204.00
IUUC-Aml-001717	Ailuropoda melanoleuca	95.53	0.00e+00	952.00
IUUC-Atr-002514	Amborella trichopoda	65.11	1.00e-144	506.00
IUUC-Apl-003708	Anas platyrhynchos	98.59	0.00e+00	922.00
IUUC-Aca-004611	Anolis carolinensis	98.06	0.00e+00	957.00
IUUC-Aly-005622	Arabidopsis lyrata	58.40	1.00e-119	424.00
IUUC-Ath-007137	Arabidopsis thaliana	59.50	2.00e-121	429.00
IUUC-Ame-011601	Astyanax mexicanus	92.23	0.00e+00	903.00
IUUC-Bta-012418	Bos taurus	98.64	0.00e+00	983.00
IUUC-Bdi-014315	Brachypodium distachyon	60.42	2.00e-134	472.00
IUUC-Bol-016277	Brassica oleracea	57.25	5.00e-127	447.00
IUUC-Bra-016944	Brassica rapa	60.28	3.00e-126	445.00
IUUC-Cja-018832	Callithrix jacchus	98.83	0.00e+00	955.00
IUUC-Cfa-020029	Canis familiaris	95.34	0.00e+00	951.00
IUUC-Cpo-022080	Cavia porcellus	93.41	0.00e+00	919.00
IUUC-Cre-022979	Chlamydomonas reinhardtii	60.11	3.00e-130	458.00
IUUC-Csa-024075	Chlorocebus sabaeus	95.53	0.00e+00	951.00
IUUC-Cin-025704	Ciona intestinalis	70.87	0.00e+00	785.00
IUUC-Csv-026257	Ciona savignyi	69.83	0.00e+00	761.00
IUUC-Cne-026946	Cryptococcus neoformans	38.01	2.00e-30	127.00
IUUC-Cme-027258	Cyanidioschyzon merolae	39.65	2.00e-105	376.00
IUUC-Dre-028075	Danio rerio	95.92	0.00e+00	929.00
IUUC-Dno-029196	Dasypus novemcinctus	99.03	0.00e+00	962.00
IUUC-Dor-030732	Dipodomys ordii	98.90	0.00e+00	730.00
IUUC-Dme-031939	Drosophila melanogaster	81.15	4.00e-173	601.00
IUUC-Ete-032822	Echinops telfairi	78.81	0.00e+00	794.00
IUUC-Eca-033897	Equus caballus	87.86	0.00e+00	935.00
IUUC-Eeu-034952	Erinaceus europaeus	89.04	0.00e+00	822.00
IUUC-Fca-035734	Felis catus	98.64	0.00e+00	962.00
IUUC-Fal-037185	Ficedula albicollis	98.83	0.00e+00	962.00
IUUC-Gmo-038870	Gadus morhua	90.10	0.00e+00	929.00
IUUC-Gga-041161	Gallus gallus	98.83	0.00e+00	964.00
IUUC-Gac-041844	Gasterosteus aculeatus	95.53	0.00e+00	959.00
IUUC-Gma-044208	Glycine max	48.17	3.00e-152	531.00
IUUC-Ggo-044882	Gorilla gorilla	95.53	0.00e+00	951.00
IUUC-Hsa-046488	Homo sapiens	95.53	0.00e+00	951.00
IUUC-Itr-047958	Ictidomys tridecemlineatus	99.45	0.00e+00	737.00
IUUC-Lch-050672	Latimeria chalumnae	96.70	0.00e+00	974.00
IUUC-Lpe-051084	Leersia perrieri	62.91	8.00e-137	480.00
IUUC-Loc-052030	Lepisosteus oculatus	95.95	0.00e+00	963.00
IUUC-Laf-054280	Loxodonta africana	98.25	0.00e+00	983.00
IUUC-Mcc-055203	Macaca mulatta	95.53	0.00e+00	950.00
IUUC-Meu-056563	Macropus eugenii	99.16	6.00e-136	477.00
IUUC-Mtr-058624	Medicago truncatula	60.16	2.00e-128	452.00
IUUC-Mga-059660	Meleagris gallopavo	98.83	0.00e+00	964.00
IUUC-Mvi-060557	Microbotryum violaceum	36.77	7.00e-71	262.00
IUUC-Mmr-060925	Microcebus murinus	97.41	0.00e+00	914.00
IUUC-Mmu-063603	Mus musculus	98.45	0.00e+00	958.00
IUUC-Mac-065508	Musa acuminata	46.15	8.00e-109	387.00
IUUC-Mpu-066741	Mustela putorius furo	95.34	0.00e+00	951.00
IUUC-Mlu-068152	Myotis lucifugus	98.83	0.00e+00	955.00
IUUC-Nle-069229	Nomascus leucogenys	95.53	0.00e+00	951.00
IUUC-Opr-070277	Ochotona princeps	87.99	0.00e+00	812.00
IUUC-Ont-072623	Oreochromis niloticus	95.15	0.00e+00	960.00
IUUC-Oan-073562	Ornithorhynchus anatinus	88.07	0.00e+00	939.00
IUUC-Ocu-074280	Oryctolagus cuniculus	96.95	0.00e+00	950.00
IUUC-Oba-075618	Oryza barthii	48.65	1.00e-144	506.00
IUUC-Obr-076718	Oryza brachyantha	59.95	1.00e-136	479.00
IUUC-Ogl-077302	Oryza glaberrima	50.63	3.00e-156	545.00
IUUC-Ogu-078718	Oryza glumaepatula	50.63	3.00e-156	545.00
IUUC-Oin-079515	Oryza indica	44.12	2.00e-94	340.00
IUUC-Olo-080427	Oryza longistaminata	63.04	1.00e-131	463.00
IUUC-Ome-081696	Oryza meridionalis	49.55	4.00e-151	528.00
IUUC-Oni-082137	Oryza nivara	50.63	3.00e-156	545.00
IUUC-Opu-083505	Oryza punctata	48.83	2.00e-144	505.00
IUUC-Oru-085276	Oryza rufipogon	50.45	9.00e-156	543.00
IUUC-Osa-085791	Oryza sativa	50.63	3.00e-156	545.00
IUUC-Ola-087365	Oryzias latipes	95.15	0.00e+00	957.00
IUUC-Olu-087589	Ostreococcus lucimarinus	51.96	6.00e-155	540.00
IUUC-Oga-088357	Otolemur garnettii	94.76	0.00e+00	902.00
IUUC-Oar-089214	Ovis aries	98.83	0.00e+00	986.00
IUUC-Ptr-091532	Pan troglodytes	95.53	0.00e+00	951.00
IUUC-Pan-091927	Papio anubis	95.53	0.00e+00	951.00
IUUC-Psi-093941	Pelodiscus sinensis	92.79	0.00e+00	937.00
IUUC-Pma-094105	Petromyzon marinus	65.65	9.00e-101	359.00
IUUC-Ppa-095868	Physcomitrella patens	66.30	2.00e-139	488.00
IUUC-Pfo-096158	Poecilia formosa	95.34	0.00e+00	960.00
IUUC-Pab-098705	Pongo abelii	95.53	0.00e+00	951.00
IUUC-Pop-098989	Populus trichocarpa	61.81	2.00e-128	452.00
IUUC-Pca-100256	Procavia capensis	98.24	0.00e+00	942.00
IUUC-Ppe-101572	Prunus persica	63.41	1.00e-127	449.00
IUUC-Pva-102616	Pteropus vampyrus	98.43	0.00e+00	941.00
IUUC-Rno-105411	Rattus norvegicus	98.64	0.00e+00	961.00
IUUC-Sha-106636	Sarcophilus harrisii	99.42	0.00e+00	963.00
IUUC-Smo-109301	Selaginella moellendorffii	63.76	3.00e-143	501.00
IUUC-Sit-110710	Setaria italica	63.43	5.00e-142	498.00
IUUC-Sly-111042	Solanum lycopersicum	50.58	7.00e-150	523.00
IUUC-Stu-112744	Solanum tuberosum	50.19	3.00e-142	498.00
IUUC-Sar-112971	Sorex araneus	87.08	0.00e+00	863.00
IUUC-Sbi-114420	Sorghum bicolor	62.91	7.00e-142	497.00
IUUC-Sre-115175	Sporisorium reilianum	37.50	3.00e-58	220.00
IUUC-Ssc-115695	Sus scrofa	97.09	0.00e+00	940.00
IUUC-Tgu-117009	Taeniopygia guttata	98.82	0.00e+00	947.00
IUUC-Tru-118581	Takifugu rubripes	94.76	0.00e+00	961.00
IUUC-Tsy-119424	Tarsius syrichta	81.69	0.00e+00	730.00
IUUC-Tni-119986	Tetraodon nigroviridis	94.95	0.00e+00	961.00
IUUC-Tca-121739	Theobroma cacao	53.83	1.00e-124	439.00
IUUC-Tae-125368	Triticum aestivum	59.74	3.00e-135	475.00
IUUC-Tur-126856	Triticum urartu	60.61	7.00e-62	231.00
IUUC-Tme-127126	Tuber melanosporum	38.24	2.00e-58	220.00
IUUC-Tbe-127665	Tupaia belangeri	83.07	0.00e+00	825.00
IUUC-Ttr-128826	Tursiops truncatus	87.14	0.00e+00	855.00
IUUC-Uma-129469	Ustilago maydis	42.75	2.00e-58	221.00
IUUC-Vpa-130768	Vicugna pacos	95.10	0.00e+00	936.00
IUUC-Vvi-131193	Vitis vinifera	60.44	4.00e-129	455.00
IUUC-Xtr-132842	Xenopus tropicalis	92.38	0.00e+00	912.00
IUUC-Xma-134020	Xiphophorus maculatus	95.34	0.00e+00	960.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence