iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048585

Ensembl Protein ID

ENSSTOP00000003812.2

UniProt Accession

I3M3W1; I3M3W1_ICTTR

Genbank Protein ID

ENSSTOP00000003812

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01095633

Gene Name

SOCS4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000004262.2	ENSSTOT00000004245.2	ENSSTOP00000003812.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	6.80e-17	61.1	373	420

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 3    klwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
           +++l+r+ p+SLqh+CR +I++c++++++   d+LP+P s+k YL++++y+
   Q: 373  STPLIRTFPFSLQHICRTVICNCTTYDGI---DALPIPTSMKLYLKEYHYK 420
           678899***********************...****************985 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

SENNSKNIDV RPKTSRSRSA DRKDGYVWSG KKLSWSKKSE SCSDAETVDT IEKTEVPLRS 60
QERNHSCSSI ELDLDHSCGH RFLGRSLKQK LQDAVGQCFP IKNCSSRHSS GLPSKRKIHI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTGAAAATA ATAGTAAAAA TATAGATGTA AGACCCAAAA CTAGTCGAAG TAGAAGTGCT 60
GACAGAAAGG ATGGTTATGT GTGGAGTGGA AAGAAGTTGT CTTGGTCCAA AAAGAGTGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028416--SOCS4
IPR022252--SOCS4/SOCS5_dom
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF12610--SOCS
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0007175--P:negative regulation of epidermal growth factor-activated receptor activity
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001789	Ailuropoda melanoleuca	94.24	0.00e+00	793.00
IUUC-Apl-003839	Anas platyrhynchos	80.60	0.00e+00	635.00
IUUC-Aca-004840	Anolis carolinensis	79.91	0.00e+00	694.00
IUUC-Bta-012503	Bos taurus	94.48	0.00e+00	787.00
IUUC-Bol-016597	Brassica oleracea	29.11	1.40e-01	31.20
IUUC-Cja-019284	Callithrix jacchus	93.79	0.00e+00	784.00
IUUC-Cfa-020890	Canis familiaris	93.79	0.00e+00	786.00
IUUC-Cpo-022081	Cavia porcellus	78.10	0.00e+00	666.00
IUUC-Csa-023076	Chlorocebus sabaeus	93.33	0.00e+00	782.00
IUUC-Cho-024700	Choloepus hoffmanni	93.58	0.00e+00	818.00
IUUC-Dno-029961	Dasypus novemcinctus	94.27	0.00e+00	820.00
IUUC-Dor-030273	Dipodomys ordii	94.27	0.00e+00	791.00
IUUC-Ete-032972	Echinops telfairi	94.21	2.00e-171	593.00
IUUC-Eca-034289	Equus caballus	94.04	0.00e+00	786.00
IUUC-Eeu-035208	Erinaceus europaeus	90.57	0.00e+00	749.00
IUUC-Fal-036829	Ficedula albicollis	79.91	0.00e+00	629.00
IUUC-Gga-040725	Gallus gallus	78.29	0.00e+00	649.00
IUUC-Ggo-044886	Gorilla gorilla	93.79	0.00e+00	787.00
IUUC-Hsa-046322	Homo sapiens	93.56	0.00e+00	785.00
IUUC-Lch-049459	Latimeria chalumnae	56.94	4.00e-135	474.00
IUUC-Laf-053484	Loxodonta africana	95.17	0.00e+00	796.00
IUUC-Mcc-054890	Macaca mulatta	93.10	0.00e+00	781.00
IUUC-Meu-056532	Macropus eugenii	83.38	0.00e+00	637.00
IUUC-Mvi-060418	Microbotryum violaceum	32.10	1.20e-02	32.70
IUUC-Mmr-061714	Microcebus murinus	94.72	0.00e+00	783.00
IUUC-Mmu-063161	Mus musculus	88.97	0.00e+00	750.00
IUUC-Mpu-066499	Mustela putorius furo	93.81	0.00e+00	809.00
IUUC-Mlu-066945	Myotis lucifugus	92.89	0.00e+00	771.00
IUUC-Nle-069976	Nomascus leucogenys	93.56	0.00e+00	784.00
IUUC-Opr-070255	Ochotona princeps	87.36	0.00e+00	747.00
IUUC-Ocu-074764	Oryctolagus cuniculus	93.35	0.00e+00	781.00
IUUC-Oga-088910	Otolemur garnettii	87.87	0.00e+00	760.00
IUUC-Oar-090330	Ovis aries	94.25	0.00e+00	785.00
IUUC-Ptr-090709	Pan troglodytes	93.79	0.00e+00	787.00
IUUC-Pan-092540	Papio anubis	93.33	0.00e+00	782.00
IUUC-Psi-093678	Pelodiscus sinensis	81.99	0.00e+00	714.00
IUUC-Pfo-097139	Poecilia formosa	80.81	7.00e-87	314.00
IUUC-Pab-097970	Pongo abelii	91.87	0.00e+00	645.00
IUUC-Pop-098820	Populus trichocarpa	41.18	1.30e-01	30.80
IUUC-Pca-100211	Procavia capensis	82.99	0.00e+00	659.00
IUUC-Rno-106014	Rattus norvegicus	86.44	0.00e+00	737.00
IUUC-Sha-106822	Sarcophilus harrisii	83.45	0.00e+00	717.00
IUUC-Ssc-115821	Sus scrofa	94.72	0.00e+00	786.00
IUUC-Tgu-117117	Taeniopygia guttata	80.37	0.00e+00	632.00
IUUC-Tsy-118979	Tarsius syrichta	96.17	3.00e-126	443.00
IUUC-Tca-121131	Theobroma cacao	30.77	2.00e-03	36.20
IUUC-Vpa-130626	Vicugna pacos	94.23	0.00e+00	791.00
IUUC-Vvi-131327	Vitis vinifera	43.75	9.40e-02	31.20

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence