iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-021140

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03000432

Gene Name

RNF146

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000001068.2	ENSCAFT00000001634.2	ENSCAFP00000001501.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	91.64	2.00e-165	579.00	IUUC-Hsa-045790

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Canis familiaris

Protein Sequence
(Fasta)

MMAGCGEVDH SINMLPTNRK ANESCSNTAP SLTVPECAIC LQTCVHPVSL PCKHVFCYLC 60
VKGASWLGKR CALCRQEIPE DFLDKPTLLS PEELKAASRG NGEYAWYYEG RNGWWQYDER 120

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Nucleotide Sequence
(Fasta)

GTCCTGGGCG GGGCCTGGGC GGGGCCCGGG CTCCACTTCC GGCCCCCGCG GCCCCGCCCC 60
CCGCGGCGCG ACGGCGGGTC ACGTGACGGC CGCGCGCGTT CCCGGCCGCT GCGGGCTCCG 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR033509--RNF146
IPR004170--WWE-dom
IPR018123--WWE-dom_subgr
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50918--WWE
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02825--WWE

SMART

SM00184--RING
SM00678--WWE

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0072572--F:poly-ADP-D-ribose binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0090263--P:positive regulation of canonical Wnt signaling pathway
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0016055--P:Wnt signaling pathway

KEGG

cfa:476288

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002237	Ailuropoda melanoleuca	89.14	9.00e-150	522.00
IUUC-Apl-004143	Anas platyrhynchos	81.62	1.00e-130	459.00
IUUC-Aca-004557	Anolis carolinensis	78.06	2.00e-124	438.00
IUUC-Ame-011088	Astyanax mexicanus	61.72	9.00e-83	300.00
IUUC-Bta-012639	Bos taurus	90.53	1.00e-145	508.00
IUUC-Cel-018462	Caenorhabditis elegans	28.35	1.00e-18	86.70
IUUC-Cja-019397	Callithrix jacchus	91.92	2.00e-155	541.00
IUUC-Cpo-021387	Cavia porcellus	86.07	2.00e-158	551.00
IUUC-Csa-023503	Chlorocebus sabaeus	88.30	7.00e-148	516.00
IUUC-Cho-024895	Choloepus hoffmanni	87.83	2.00e-134	471.00
IUUC-Cin-025455	Ciona intestinalis	53.29	5.00e-43	166.00
IUUC-Dre-028824	Danio rerio	55.56	4.00e-80	291.00
IUUC-Dno-029269	Dasypus novemcinctus	90.25	1.00e-153	535.00
IUUC-Dor-030592	Dipodomys ordii	88.61	3.00e-156	544.00
IUUC-Dme-031618	Drosophila melanogaster	56.77	1.00e-55	210.00
IUUC-Ete-032478	Echinops telfairi	89.42	5.00e-157	546.00
IUUC-Eca-033389	Equus caballus	91.62	1.00e-171	595.00
IUUC-Fca-035488	Felis catus	92.46	5.00e-156	543.00
IUUC-Fal-037087	Ficedula albicollis	82.50	5.00e-149	520.00
IUUC-Gga-040401	Gallus gallus	83.89	3.00e-133	468.00
IUUC-Gac-042412	Gasterosteus aculeatus	63.77	8.00e-86	310.00
IUUC-Ggo-045417	Gorilla gorilla	91.61	2.00e-147	514.00
IUUC-Hsa-045790	Homo sapiens	91.64	7.00e-155	539.00
IUUC-Itr-048820	Ictidomys tridecemlineatus	89.94	1.00e-159	555.00
IUUC-Lch-049493	Latimeria chalumnae	85.02	3.00e-104	371.00
IUUC-Loc-052927	Lepisosteus oculatus	67.48	5.00e-101	360.00
IUUC-Laf-053904	Loxodonta africana	90.25	3.00e-154	538.00
IUUC-Mcc-055427	Macaca mulatta	88.33	3.00e-155	541.00
IUUC-Mmr-060580	Microcebus murinus	89.72	2.00e-149	521.00
IUUC-Mdo-062094	Monodelphis domestica	96.21	8.00e-78	281.00
IUUC-Mmu-063363	Mus musculus	88.30	7.00e-157	546.00
IUUC-Mpu-066816	Mustela putorius furo	92.20	1.00e-152	532.00
IUUC-Mlu-067433	Myotis lucifugus	90.81	6.00e-172	596.00
IUUC-Nle-068986	Nomascus leucogenys	90.81	4.00e-159	553.00
IUUC-Ont-072670	Oreochromis niloticus	59.85	1.00e-79	290.00
IUUC-Oan-073330	Ornithorhynchus anatinus	87.56	8.00e-106	375.00
IUUC-Ocu-074161	Oryctolagus cuniculus	89.72	1.00e-157	548.00
IUUC-Ola-086902	Oryzias latipes	61.45	8.00e-84	303.00
IUUC-Oga-089159	Otolemur garnettii	89.97	5.00e-167	580.00
IUUC-Oar-089586	Ovis aries	91.09	1.00e-140	492.00
IUUC-Ptr-090987	Pan troglodytes	91.64	7.00e-155	539.00
IUUC-Pan-091867	Papio anubis	88.30	3.00e-154	537.00
IUUC-Psi-094024	Pelodiscus sinensis	82.78	3.00e-135	474.00
IUUC-Pma-094453	Petromyzon marinus	63.31	5.00e-64	238.00
IUUC-Pfo-097108	Poecilia formosa	70.73	9.00e-83	300.00
IUUC-Pab-097997	Pongo abelii	90.22	2.00e-159	554.00
IUUC-Pca-100260	Procavia capensis	88.55	1.00e-155	542.00
IUUC-Pva-103140	Pteropus vampyrus	90.83	1.00e-158	551.00
IUUC-Rno-105795	Rattus norvegicus	86.39	2.00e-156	544.00
IUUC-Sha-107033	Sarcophilus harrisii	86.11	1.00e-150	525.00
IUUC-Ssc-116395	Sus scrofa	91.64	3.00e-163	567.00
IUUC-Tgu-116685	Taeniopygia guttata	81.34	5.00e-131	460.00
IUUC-Tru-118014	Takifugu rubripes	65.10	2.00e-84	305.00
IUUC-Tsy-119326	Tarsius syrichta	85.28	4.00e-161	560.00
IUUC-Tni-120322	Tetraodon nigroviridis	70.42	1.00e-81	296.00
IUUC-Tbe-128067	Tupaia belangeri	90.28	5.00e-163	566.00
IUUC-Ttr-128530	Tursiops truncatus	92.78	4.00e-159	553.00
IUUC-Vpa-130322	Vicugna pacos	92.48	9.00e-163	566.00
IUUC-Xtr-132606	Xenopus tropicalis	64.27	1.00e-113	402.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence