iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-090987

UUCD1 version

UUC-PaT-00635

Ensembl Protein ID

ENSPTRP00000031718.3

UniProt Accession

H2QTP9; H2QTP9_PANTR

Genbank Protein ID

JAA05500.1; JAA17010.1; JAA37482.1

Protein Name

Ring finger protein 146

Genbank Nucleotide ID

AACZ03044702; GABF01005135; GABE01007257

Gene Name

RNF146

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000018579.5	ENSPTRT00000034314.3	ENSPTRP00000031718.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	100.00	2.00e-166	582.00	IUUC-Hsa-045790

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MMAGCGEIDH SINMLPTNRK ANESCSNTAP SLTVPECAIC LQTCVHPVSL PCKHVFCYLC 60
VKGASWLGKR CALCRQEIPE DFLDKPTLLS PEELKAASRG NGEYAWYYEG RNGWWQYDER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGCGTTCCC GGCAGCTGCG GGCTCCGAGG CCAGAGAGAA AAGACTGCGA GGTGGCCGCA 60
GCTGTGGCCG GAGAGGTGGG AGTCGGAGCG AGGCCCTCTC GGGGGAGCAG GGTGAACGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR033509--RNF146
IPR004170--WWE-dom
IPR018123--WWE-dom_subgr
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50918--WWE
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02825--WWE

SMART

SM00184--RING
SM00678--WWE

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0072572--F:poly-ADP-D-ribose binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0090263--P:positive regulation of canonical Wnt signaling pathway
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0016055--P:Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002237	Ailuropoda melanoleuca	91.36	6.00e-155	540.00
IUUC-Apl-004143	Anas platyrhynchos	84.72	2.00e-134	472.00
IUUC-Aca-004557	Anolis carolinensis	81.44	9.00e-128	449.00
IUUC-Ame-011088	Astyanax mexicanus	61.09	2.00e-83	302.00
IUUC-Bta-012639	Bos taurus	92.76	2.00e-150	525.00
IUUC-Cel-018462	Caenorhabditis elegans	28.35	6.00e-19	87.40
IUUC-Cja-019397	Callithrix jacchus	99.72	4.00e-167	580.00
IUUC-Cfa-021140	Canis familiaris	91.64	9.00e-167	579.00
IUUC-Cpo-021387	Cavia porcellus	90.53	1.00e-166	578.00
IUUC-Csa-023503	Chlorocebus sabaeus	94.15	4.00e-157	546.00
IUUC-Cho-024895	Choloepus hoffmanni	93.75	7.00e-145	506.00
IUUC-Cin-025455	Ciona intestinalis	51.92	4.00e-43	167.00
IUUC-Dre-028824	Danio rerio	45.99	1.00e-82	300.00
IUUC-Dno-029269	Dasypus novemcinctus	95.26	9.00e-162	562.00
IUUC-Dor-030592	Dipodomys ordii	94.17	2.00e-164	571.00
IUUC-Dme-031618	Drosophila melanogaster	57.33	1.00e-55	210.00
IUUC-Ete-032478	Echinops telfairi	92.48	7.00e-163	566.00
IUUC-Eca-033389	Equus caballus	96.37	0.00e+00	625.00
IUUC-Fca-035488	Felis catus	96.09	2.00e-163	567.00
IUUC-Fal-037087	Ficedula albicollis	83.89	3.00e-154	537.00
IUUC-Gmo-039713	Gadus morhua	36.62	5.00e-08	55.80
IUUC-Gga-040401	Gallus gallus	85.83	1.00e-138	486.00
IUUC-Gac-042412	Gasterosteus aculeatus	64.53	1.00e-87	316.00
IUUC-Ggo-045417	Gorilla gorilla	99.07	1.00e-159	555.00
IUUC-Hsa-045790	Homo sapiens	100.00	8.00e-168	582.00
IUUC-Itr-048820	Ictidomys tridecemlineatus	94.97	2.00e-165	575.00
IUUC-Lch-049493	Latimeria chalumnae	69.08	1.00e-110	392.00
IUUC-Loc-052927	Lepisosteus oculatus	60.00	6.00e-102	363.00
IUUC-Laf-053904	Loxodonta africana	93.87	4.00e-160	556.00
IUUC-Mcc-055427	Macaca mulatta	94.17	8.00e-164	569.00
IUUC-Mmr-060580	Microcebus murinus	96.94	2.00e-159	554.00
IUUC-Mdo-062094	Monodelphis domestica	96.97	1.00e-78	284.00
IUUC-Mmu-063363	Mus musculus	92.48	5.00e-165	573.00
IUUC-Mpu-066816	Mustela putorius furo	95.26	4.00e-158	550.00
IUUC-Mlu-067433	Myotis lucifugus	95.26	2.00e-180	624.00
IUUC-Nle-068986	Nomascus leucogenys	99.16	1.00e-180	625.00
IUUC-Opr-071117	Ochotona princeps	39.06	6.00e-07	51.60
IUUC-Ont-072670	Oreochromis niloticus	58.42	3.00e-81	295.00
IUUC-Oan-073330	Ornithorhynchus anatinus	87.06	3.00e-107	380.00
IUUC-Ocu-074161	Oryctolagus cuniculus	93.61	3.00e-164	570.00
IUUC-Ola-086902	Oryzias latipes	58.91	3.00e-84	305.00
IUUC-Oga-089159	Otolemur garnettii	94.43	0.00e+00	638.00
IUUC-Oar-089586	Ovis aries	94.15	3.00e-146	511.00
IUUC-Pan-091867	Papio anubis	94.15	5.00e-163	566.00
IUUC-Psi-094024	Pelodiscus sinensis	85.28	3.00e-142	497.00
IUUC-Pma-094453	Petromyzon marinus	63.91	4.00e-65	241.00
IUUC-Pfo-097108	Poecilia formosa	70.73	9.00e-84	303.00
IUUC-Pab-097997	Pongo abelii	98.04	1.00e-173	602.00
IUUC-Pca-100260	Procavia capensis	92.46	2.00e-164	571.00
IUUC-Pva-103140	Pteropus vampyrus	94.72	2.00e-165	574.00
IUUC-Rno-105795	Rattus norvegicus	86.67	4.00e-163	566.00
IUUC-Sha-107033	Sarcophilus harrisii	88.61	9.00e-156	542.00
IUUC-Ssc-116395	Sus scrofa	97.21	0.00e+00	627.00
IUUC-Tgu-116685	Taeniopygia guttata	81.06	4.00e-135	474.00
IUUC-Tru-118014	Takifugu rubripes	74.88	6.00e-84	303.00
IUUC-Tsy-119326	Tarsius syrichta	90.00	5.00e-177	613.00
IUUC-Tni-120322	Tetraodon nigroviridis	69.95	4.00e-82	298.00
IUUC-Tbe-128067	Tupaia belangeri	95.83	2.00e-171	594.00
IUUC-Ttr-128530	Tursiops truncatus	96.67	9.00e-165	572.00
IUUC-Vpa-130322	Vicugna pacos	97.49	1.00e-171	595.00
IUUC-Xtr-132606	Xenopus tropicalis	66.20	2.00e-118	418.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence