iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oga-088272

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03026661

Gene Name

WDR61

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000006755.2	ENSOGAT00000006758.2	ENSOGAP00000006046.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.90e-45	149.5	230	269
UBD/Beta-Prp	1.20e-74	251.2	12	304

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH+++v  +af +d t++vs+s D+++kvWD+ t +++++
   Q: 230  GHASWVLNVAFcPDdTHFVSSSSDKSVKVWDVGTRTCVHT 269
           8***********777*****************99999875 PP

UBD/Beta-Prp

   S: 6    kghhksvitcvkf.spdk...sllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvh 88
           +++h++ i +v++ s++k   + ++tgs d+ +kvw++++ kl   +sl+gh+ +v +v++s++ +i +++s D++i++wdl++gk++ 
   Q: 12   EQAHDDAIWSVAWgSNKKeiaETVVTGSLDDLVKVWKWRDDKLdlQWSLEGHQLGVVSVDISNTLPIAASSSLDAHIRLWDLENGKQIK 100
           567777888899986665222579******************9999******************************************* PP
   S: 89   tlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltg 177
           ++ +   ++++l+fsp++++l++G+h+  ++++ +e+g++ +  l+ + +++ +++++pdg++l+sG+ D++++++d++tgkll+tl+g
   Q: 101  SIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEY-SLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEG 188
           ******************************************.*********************************************9 PP
   S: 178  ghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnss 266
            h  +++sl+f+++++ lv++s+dg++k++d+q+ +   tl gh ++v+ v+f+p+d+++vs ssD+s+++Wd+ ++++++t+  h+++
   Q: 189  -HAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQ 276
           .**************************************************************************************** PP
   S: 267  visvavlsfgdnvlvlgsedskvniwklk 295
           v+ v++ + +++++v++++d++++i+++ 
   Q: 277  VWGVKY-NGNGSKIVSVGDDQEIHIYDCP 304
           ******.999*****************85 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MTNQYSILFK QEQAHDDAIW SVAWGSNKKE IAETVVTGSL DDLVKVWKWR DDKLDLQWSL 60
EGHQLGVVSV DISNTLPIAA SSSLDAHIRL WDLENGKQIK SIDAGPVDAW TLAFSPDSQY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AACCTTCTAT AGCTTCCTAT CATGATGACA CCTCCTTACC AAAACACTGG TGTTGTTTCC 60
ACAGAGCTGT CTGGTCTTTT TCCCTTCATC CTTGGTTAAG GAAATGACCA ACCAGGTAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR013979--TIF_beta_prop-like
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08662--eIF2A
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016593--C:Cdc73/Paf1 complex
GO:0005829--C:cytosol
GO:0055087--C:Ski complex
GO:0035327--C:transcriptionally active chromatin
GO:0080182--P:histone H3-K4 trimethylation
GO:0045638--P:negative regulation of myeloid cell differentiation
GO:0051571--P:positive regulation of histone H3-K4 methylation
GO:2001162--P:positive regulation of histone H3-K79 methylation
GO:0032968--P:positive regulation of transcription elongation from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000774	Aegilops tauschii	34.23	6.00e-48	184.00
IUUC-Aml-002245	Ailuropoda melanoleuca	97.37	4.00e-165	573.00
IUUC-Atr-003142	Amborella trichopoda	51.55	2.00e-38	152.00
IUUC-Apl-003179	Anas platyrhynchos	90.46	7.00e-155	539.00
IUUC-Aca-004880	Anolis carolinensis	88.49	5.00e-156	543.00
IUUC-Aly-005956	Arabidopsis lyrata	38.14	5.00e-56	211.00
IUUC-Ath-007230	Arabidopsis thaliana	37.82	6.00e-52	197.00
IUUC-Acl-008297	Aspergillus clavatus	28.88	2.00e-25	109.00
IUUC-Ang-009702	Aspergillus niger	30.55	2.00e-30	126.00
IUUC-Ame-011511	Astyanax mexicanus	83.66	2.00e-147	514.00
IUUC-Bgr-012189	Blumeria graminis	30.82	8.00e-29	120.00
IUUC-Bta-012936	Bos taurus	98.68	1.00e-166	578.00
IUUC-Bdi-015020	Brachypodium distachyon	37.93	1.00e-47	183.00
IUUC-Bol-016345	Brassica oleracea	38.78	4.00e-57	214.00
IUUC-Bra-017323	Brassica rapa	38.78	3.00e-57	215.00
IUUC-Cja-019961	Callithrix jacchus	97.70	3.00e-165	574.00
IUUC-Cfa-020862	Canis familiaris	97.04	3.00e-164	570.00
IUUC-Cpo-021356	Cavia porcellus	97.34	2.00e-162	564.00
IUUC-Cre-022602	Chlamydomonas reinhardtii	41.58	1.00e-57	216.00
IUUC-Csa-024067	Chlorocebus sabaeus	97.37	8.00e-165	572.00
IUUC-Cho-024421	Choloepus hoffmanni	83.76	2.00e-82	297.00
IUUC-Cin-025261	Ciona intestinalis	64.47	2.00e-115	408.00
IUUC-Cgl-026446	Colletotrichum gloeosporioides	28.30	4.00e-29	121.00
IUUC-Cne-026846	Cryptococcus neoformans	29.22	5.00e-25	108.00
IUUC-Dre-027706	Danio rerio	65.79	4.00e-109	387.00
IUUC-Dno-029084	Dasypus novemcinctus	97.39	2.00e-164	571.00
IUUC-Dor-030353	Dipodomys ordii	81.52	6.00e-121	426.00
IUUC-Dse-031348	Dothistroma septosporum	29.08	2.00e-26	113.00
IUUC-Dme-031836	Drosophila melanogaster	52.62	6.00e-89	320.00
IUUC-Ete-032261	Echinops telfairi	95.39	4.00e-160	556.00
IUUC-Eca-034231	Equus caballus	89.80	7.00e-150	522.00
IUUC-Eeu-034828	Erinaceus europaeus	96.21	9.00e-154	535.00
IUUC-Fca-036569	Felis catus	97.70	8.00e-165	572.00
IUUC-Fal-037469	Ficedula albicollis	92.43	8.00e-159	552.00
IUUC-Fox-038047	Fusarium oxysporum	32.66	5.00e-29	121.00
IUUC-Gmo-039579	Gadus morhua	83.88	1.00e-144	505.00
IUUC-Gga-040808	Gallus gallus	93.13	3.00e-152	530.00
IUUC-Gac-042100	Gasterosteus aculeatus	83.88	9.00e-146	509.00
IUUC-Gma-043509	Glycine max	41.25	5.00e-60	224.00
IUUC-Ggo-045227	Gorilla gorilla	97.70	3.00e-165	574.00
IUUC-Hsa-045839	Homo sapiens	97.70	3.00e-165	574.00
IUUC-Hvu-047591	Hordeum vulgare	38.49	4.00e-50	191.00
IUUC-Itr-048741	Ictidomys tridecemlineatus	98.03	4.00e-166	576.00
IUUC-Lch-049549	Latimeria chalumnae	83.22	4.00e-145	507.00
IUUC-Lpe-050746	Leersia perrieri	38.59	3.00e-48	185.00
IUUC-Loc-052540	Lepisosteus oculatus	86.51	3.00e-147	514.00
IUUC-Lma-052992	Leptosphaeria maculans	28.14	2.00e-27	116.00
IUUC-Laf-053907	Loxodonta africana	98.03	4.00e-166	576.00
IUUC-Mcc-055828	Macaca mulatta	91.36	3.00e-161	560.00
IUUC-Meu-056075	Macropus eugenii	94.12	2.00e-134	471.00
IUUC-Mtr-057728	Medicago truncatula	40.71	6.00e-57	214.00
IUUC-Mga-059872	Meleagris gallopavo	92.76	1.00e-159	555.00
IUUC-Mvi-060564	Microbotryum violaceum	31.77	5.00e-29	121.00
IUUC-Mmr-060985	Microcebus murinus	95.05	2.00e-157	547.00
IUUC-Mdo-062758	Monodelphis domestica	90.13	2.00e-157	547.00
IUUC-Mmu-063580	Mus musculus	96.05	8.00e-164	569.00
IUUC-Mac-064880	Musa acuminata	39.87	4.00e-57	214.00
IUUC-Mpu-066577	Mustela putorius furo	97.37	2.00e-165	574.00
IUUC-Nle-069573	Nomascus leucogenys	97.70	3.00e-165	574.00
IUUC-Opr-070216	Ochotona princeps	96.67	2.00e-161	561.00
IUUC-Ont-071981	Oreochromis niloticus	85.20	2.00e-148	518.00
IUUC-Oan-073223	Ornithorhynchus anatinus	93.91	1.00e-106	378.00
IUUC-Ocu-074199	Oryctolagus cuniculus	83.61	8.00e-137	479.00
IUUC-Oba-075255	Oryza barthii	40.00	8.00e-42	163.00
IUUC-Obr-076168	Oryza brachyantha	47.20	1.00e-35	143.00
IUUC-Ogl-077777	Oryza glaberrima	38.71	3.00e-49	188.00
IUUC-Ogu-078780	Oryza glumaepatula	38.71	3.00e-49	188.00
IUUC-Oin-079228	Oryza indica	38.71	6.00e-52	197.00
IUUC-Olo-080617	Oryza longistaminata	45.77	2.00e-29	120.00
IUUC-Ome-081421	Oryza meridionalis	38.71	2.00e-48	186.00
IUUC-Oni-082997	Oryza nivara	38.71	6.00e-52	197.00
IUUC-Opu-083931	Oryza punctata	38.91	8.00e-49	187.00
IUUC-Oru-084645	Oryza rufipogon	38.71	3.00e-49	188.00
IUUC-Osa-085842	Oryza sativa	38.71	6.00e-52	197.00
IUUC-Ola-086696	Oryzias latipes	84.54	5.00e-144	503.00
IUUC-Olu-087643	Ostreococcus lucimarinus	39.91	1.00e-41	162.00
IUUC-Oar-089416	Ovis aries	98.68	1.00e-166	578.00
IUUC-Ptr-090944	Pan troglodytes	97.70	3.00e-165	574.00
IUUC-Pan-091861	Papio anubis	97.70	3.00e-165	574.00
IUUC-Psi-093750	Pelodiscus sinensis	93.42	5.00e-160	556.00
IUUC-Pma-094608	Petromyzon marinus	80.26	7.00e-135	473.00
IUUC-Pno-094832	Phaeosphaeria nodorum	32.59	2.00e-26	112.00
IUUC-Ppa-095737	Physcomitrella patens	40.71	5.00e-57	214.00
IUUC-Pfo-096479	Poecilia formosa	85.86	2.00e-143	501.00
IUUC-Pab-098179	Pongo abelii	97.70	3.00e-165	574.00
IUUC-Pop-099532	Populus trichocarpa	41.26	1.00e-56	213.00
IUUC-Pca-100664	Procavia capensis	75.72	8.00e-105	372.00
IUUC-Ppe-102056	Prunus persica	40.26	2.00e-58	218.00
IUUC-Pva-102859	Pteropus vampyrus	97.70	5.00e-165	573.00
IUUC-Pte-104236	Pyrenophora teres	35.56	2.00e-25	109.00
IUUC-Rno-105826	Rattus norvegicus	95.72	3.00e-163	567.00
IUUC-Sha-106660	Sarcophilus harrisii	91.39	1.00e-151	528.00
IUUC-Sja-107800	Schizosaccharomyces japonicus	33.55	3.00e-37	148.00
IUUC-Spo-108244	Schizosaccharomyces pombe	31.25	1.00e-35	143.00
IUUC-Smo-109234	Selaginella moellendorffii	44.04	2.00e-61	229.00
IUUC-Sit-110048	Setaria italica	37.85	3.00e-41	162.00
IUUC-Sly-111618	Solanum lycopersicum	38.46	2.00e-52	199.00
IUUC-Stu-112543	Solanum tuberosum	38.78	2.00e-55	209.00
IUUC-Sar-113743	Sorex araneus	77.30	1.00e-128	452.00
IUUC-Sbi-114309	Sorghum bicolor	39.58	2.00e-42	166.00
IUUC-Ssc-115560	Sus scrofa	92.76	2.00e-153	534.00
IUUC-Tgu-117300	Taeniopygia guttata	92.76	2.00e-159	554.00
IUUC-Tru-117933	Takifugu rubripes	84.87	5.00e-148	516.00
IUUC-Tsy-119574	Tarsius syrichta	87.17	6.00e-142	496.00
IUUC-Tni-120191	Tetraodon nigroviridis	87.29	4.00e-112	397.00
IUUC-Tca-120983	Theobroma cacao	40.45	9.00e-58	216.00
IUUC-Tae-124056	Triticum aestivum	36.86	5.00e-50	191.00
IUUC-Tur-126711	Triticum urartu	36.56	4.00e-49	188.00
IUUC-Tme-127066	Tuber melanosporum	33.83	3.00e-34	139.00
IUUC-Tbe-127802	Tupaia belangeri	97.70	8.00e-165	572.00
IUUC-Ttr-128861	Tursiops truncatus	95.28	2.00e-54	205.00
IUUC-Vda-129720	Verticillium dahliae	29.27	1.00e-22	100.00
IUUC-Vpa-130618	Vicugna pacos	93.93	4.00e-133	466.00
IUUC-Vvi-130981	Vitis vinifera	40.71	3.00e-56	211.00
IUUC-Xtr-132460	Xenopus tropicalis	85.20	1.00e-144	505.00
IUUC-Xma-134154	Xiphophorus maculatus	85.86	1.00e-143	501.00
IUUC-Yli-134554	Yarrowia lipolytica	28.04	2.00e-20	92.80

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence