iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-131908

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAMC01073228

Gene Name

pik3r4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000002330.3	ENSXETT00000004982.3	ENSXETP00000004982.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-18	66.6	989	1018

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclafsd..tllvsGsdDgtikvWD 29
           H+++v+ ++ sd   +++++s+Dgt+k+W+
   Q: 989  HKGPVNRIRVSDehSIFATCSNDGTVKIWN 1018
           999*****995546789************9 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MGNQLAGIAP SQILSVDSYF SDIHEFEYDK SLGSTRFFKV ARAKHREGLV VVKVFAIQDP 60
SLPLTNYKQE LEELKIRLCS SQNCLPFQKF TLNEKAALLF RQFVRDNLYD RISTRPFLNN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCAGCCGGGG TTTCGCTGTT ATTCTCTTGC TATGCTGATT TATCTCGCAA GACTGGCCGT 60
GTGTAGCGAA ATGGAAGTTT CAAGTCTCTG CAACAGCATG CCCTGGTACG ATGAGGGATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR021133--HEAT_type_2
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR008271--Ser/Thr_kinase_AS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50077--HEAT_REPEAT
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00069--Pkinase
PF00400--WD40

SMART

SM00220--S_TKc
SM00320--WD40

Gene Ontology

GO:0005770--C:late endosome
GO:0005643--C:nuclear pore
GO:0071561--C:nucleus-vacuole junction
GO:0034271--C:phosphatidylinositol 3-kinase complex, class III, type I
GO:0034272--C:phosphatidylinositol 3-kinase complex, class III, type II
GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0045324--P:late endosome to vacuole transport
GO:0016236--P:macroautophagy
GO:0030242--P:pexophagy
GO:0006468--P:protein phosphorylation
GO:0006623--P:protein targeting to vacuole

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000213	Aegilops tauschii	31.47	1.00e-44	175.00
IUUC-Aml-001659	Ailuropoda melanoleuca	86.31	0.00e+00	2412.00
IUUC-Atr-002968	Amborella trichopoda	32.12	1.00e-80	295.00
IUUC-Apl-003418	Anas platyrhynchos	87.57	0.00e+00	2509.00
IUUC-Aca-004344	Anolis carolinensis	87.44	0.00e+00	2258.00
IUUC-Aly-006107	Arabidopsis lyrata	45.90	2.00e-71	265.00
IUUC-Ath-007260	Arabidopsis thaliana	46.20	3.00e-72	267.00
IUUC-Ago-007721	Ashbya gossypii	31.34	3.00e-104	374.00
IUUC-Acl-008378	Aspergillus clavatus	37.77	1.00e-152	535.00
IUUC-Afl-008632	Aspergillus flavus	35.31	2.00e-142	500.00
IUUC-Afu-009020	Aspergillus fumigatus	36.35	5.00e-145	509.00
IUUC-Ani-009204	Aspergillus nidulans	35.96	1.00e-134	474.00
IUUC-Ang-009811	Aspergillus niger	34.82	2.00e-141	497.00
IUUC-Aor-010168	Aspergillus oryzae	35.31	2.00e-142	500.00
IUUC-Ate-010556	Aspergillus terreus	35.53	4.00e-143	503.00
IUUC-Ame-011955	Astyanax mexicanus	80.27	0.00e+00	1838.00
IUUC-Bgr-012050	Blumeria graminis	35.80	1.00e-141	497.00
IUUC-Bta-012432	Bos taurus	85.72	0.00e+00	2442.00
IUUC-Bci-013846	Botrytis cinerea	33.10	2.00e-142	500.00
IUUC-Bdi-015072	Brachypodium distachyon	40.32	6.00e-67	249.00
IUUC-Bol-015314	Brassica oleracea	26.73	7.00e-87	315.00
IUUC-Bra-017476	Brassica rapa	46.53	2.00e-72	268.00
IUUC-Cel-018550	Caenorhabditis elegans	31.15	2.00e-85	311.00
IUUC-Cja-019538	Callithrix jacchus	85.43	0.00e+00	2430.00
IUUC-Cfa-020483	Canis familiaris	86.15	0.00e+00	2418.00
IUUC-Cpo-021392	Cavia porcellus	85.87	0.00e+00	2442.00
IUUC-Csa-024112	Chlorocebus sabaeus	85.87	0.00e+00	2440.00
IUUC-Cho-025015	Choloepus hoffmanni	81.10	0.00e+00	865.00
IUUC-Cin-025209	Ciona intestinalis	40.96	0.00e+00	1068.00
IUUC-Csv-026334	Ciona savignyi	41.91	0.00e+00	895.00
IUUC-Cgl-026447	Colletotrichum gloeosporioides	36.24	8.00e-145	508.00
IUUC-Cne-026999	Cryptococcus neoformans	38.61	2.00e-117	417.00
IUUC-Dre-028662	Danio rerio	80.27	0.00e+00	2299.00
IUUC-Dno-029545	Dasypus novemcinctus	84.47	0.00e+00	2386.00
IUUC-Dor-030941	Dipodomys ordii	63.32	6.00e-166	578.00
IUUC-Dse-031455	Dothistroma septosporum	35.70	3.00e-136	479.00
IUUC-Dme-031726	Drosophila melanogaster	47.12	0.00e+00	745.00
IUUC-Ete-033147	Echinops telfairi	87.12	0.00e+00	939.00
IUUC-Eca-034025	Equus caballus	86.31	0.00e+00	2451.00
IUUC-Eeu-034480	Erinaceus europaeus	81.54	0.00e+00	1399.00
IUUC-Fca-035741	Felis catus	86.09	0.00e+00	2425.00
IUUC-Fal-037666	Ficedula albicollis	86.39	0.00e+00	2486.00
IUUC-Fox-037818	Fusarium oxysporum	35.07	5.00e-125	442.00
IUUC-Fso-038086	Fusarium solani	34.31	6.00e-129	455.00
IUUC-Gmo-038804	Gadus morhua	79.07	0.00e+00	726.00
IUUC-Ggr-039800	Gaeumannomyces graminis	34.55	1.00e-130	461.00
IUUC-Gga-041251	Gallus gallus	86.34	0.00e+00	1941.00
IUUC-Gac-042376	Gasterosteus aculeatus	77.78	0.00e+00	2214.00
IUUC-Gma-044095	Glycine max	44.57	1.00e-73	272.00
IUUC-Ggo-044506	Gorilla gorilla	85.44	0.00e+00	2426.00
IUUC-Hsa-045871	Homo sapiens	85.87	0.00e+00	2439.00
IUUC-Hvu-047648	Hordeum vulgare	31.49	2.00e-46	181.00
IUUC-Itr-048082	Ictidomys tridecemlineatus	89.55	0.00e+00	1113.00
IUUC-Kpa-049390	Komagataella pastoris	32.57	2.00e-129	457.00
IUUC-Lch-050284	Latimeria chalumnae	83.48	0.00e+00	2302.00
IUUC-Lpe-050880	Leersia perrieri	41.67	1.00e-64	242.00
IUUC-Loc-052815	Lepisosteus oculatus	80.95	0.00e+00	2295.00
IUUC-Lma-053324	Leptosphaeria maculans	36.32	4.00e-142	499.00
IUUC-Laf-054204	Loxodonta africana	75.53	0.00e+00	2063.00
IUUC-Mcc-054612	Macaca mulatta	85.87	0.00e+00	2439.00
IUUC-Meu-056227	Macropus eugenii	79.26	0.00e+00	791.00
IUUC-Mor-057094	Magnaporthe oryzae	35.51	2.00e-133	470.00
IUUC-Mtr-058550	Medicago truncatula	42.26	3.00e-72	267.00
IUUC-Mla-058893	Melampsora laricipopulina	35.87	1.00e-132	468.00
IUUC-Mga-059474	Meleagris gallopavo	86.56	0.00e+00	2352.00
IUUC-Mvi-060227	Microbotryum violaceum	45.74	5.00e-83	303.00
IUUC-Mmr-061543	Microcebus murinus	80.48	0.00e+00	2218.00
IUUC-Mdo-062129	Monodelphis domestica	86.87	0.00e+00	2377.00
IUUC-Mmu-064381	Mus musculus	84.63	0.00e+00	2410.00
IUUC-Mac-064455	Musa acuminata	38.07	1.00e-123	438.00
IUUC-Mpu-066151	Mustela putorius furo	89.67	0.00e+00	896.00
IUUC-Mlu-067824	Myotis lucifugus	86.24	0.00e+00	2446.00
IUUC-Nfi-068241	Neosartorya fischeri	36.90	9.00e-148	518.00
IUUC-Ncr-068964	Neurospora crassa	35.48	6.00e-139	489.00
IUUC-Nle-069152	Nomascus leucogenys	85.80	0.00e+00	2435.00
IUUC-Opr-070870	Ochotona princeps	78.58	0.00e+00	1342.00
IUUC-Ont-071293	Oreochromis niloticus	79.58	0.00e+00	2276.00
IUUC-Oan-072852	Ornithorhynchus anatinus	81.88	0.00e+00	2294.00
IUUC-Ocu-074727	Oryctolagus cuniculus	85.72	0.00e+00	2413.00
IUUC-Oba-075932	Oryza barthii	37.14	1.00e-64	242.00
IUUC-Obr-076424	Oryza brachyantha	45.74	5.00e-63	236.00
IUUC-Ogl-077491	Oryza glaberrima	37.14	1.00e-64	242.00
IUUC-Ogu-078933	Oryza glumaepatula	44.41	7.00e-68	252.00
IUUC-Oin-079604	Oryza indica	41.02	4.00e-70	259.00
IUUC-Olo-080850	Oryza longistaminata	35.22	7.00e-116	412.00
IUUC-Ome-081860	Oryza meridionalis	41.02	4.00e-70	260.00
IUUC-Oni-082895	Oryza nivara	37.14	3.00e-64	241.00
IUUC-Opu-083741	Oryza punctata	41.02	4.00e-69	257.00
IUUC-Oru-084616	Oryza rufipogon	36.87	6.00e-64	239.00
IUUC-Osa-085941	Oryza sativa	28.47	3.00e-34	139.00
IUUC-Ola-087357	Oryzias latipes	85.81	3.00e-161	560.00
IUUC-Olu-087659	Ostreococcus lucimarinus	30.61	2.00e-92	334.00
IUUC-Oga-088555	Otolemur garnettii	86.02	0.00e+00	2427.00
IUUC-Oar-089304	Ovis aries	88.97	0.00e+00	1243.00
IUUC-Ptr-091140	Pan troglodytes	85.87	0.00e+00	2440.00
IUUC-Pan-092413	Papio anubis	85.74	0.00e+00	2333.00
IUUC-Psi-093210	Pelodiscus sinensis	87.77	0.00e+00	2511.00
IUUC-Pma-094674	Petromyzon marinus	55.93	0.00e+00	719.00
IUUC-Pno-094969	Phaeosphaeria nodorum	29.91	7.00e-141	495.00
IUUC-Ppa-096017	Physcomitrella patens	42.34	2.00e-77	285.00
IUUC-Pfo-096077	Poecilia formosa	79.53	0.00e+00	2244.00
IUUC-Pab-098269	Pongo abelii	85.29	0.00e+00	2425.00
IUUC-Pop-100052	Populus trichocarpa	44.29	1.00e-66	248.00
IUUC-Pca-100377	Procavia capensis	81.85	0.00e+00	2197.00
IUUC-Ppe-101445	Prunus persica	43.21	3.00e-74	273.00
IUUC-Pva-102198	Pteropus vampyrus	87.13	0.00e+00	1622.00
IUUC-Pgr-103544	Puccinia graminis	48.26	2.00e-81	298.00
IUUC-Ptt-103964	Puccinia triticina	47.32	6.00e-79	289.00
IUUC-Pte-104196	Pyrenophora teres	36.25	2.00e-138	487.00
IUUC-Pyt-104544	Pyrenophora triticirepentis	35.85	8.00e-138	485.00
IUUC-Rno-105256	Rattus norvegicus	84.63	0.00e+00	2409.00
IUUC-Sce-106295	Saccharomyces cerevisiae	33.13	4.00e-116	413.00
IUUC-Sha-107597	Sarcophilus harrisii	86.19	0.00e+00	2413.00
IUUC-Sja-107781	Schizosaccharomyces japonicus	41.39	3.00e-71	263.00
IUUC-Spo-108031	Schizosaccharomyces pombe	43.98	1.00e-74	275.00
IUUC-Ssl-108579	Sclerotinia sclerotiorum	35.12	5.00e-136	479.00
IUUC-Smo-108679	Selaginella moellendorffii	42.15	6.00e-79	289.00
IUUC-Sit-110765	Setaria italica	41.62	5.00e-64	239.00
IUUC-Sly-111527	Solanum lycopersicum	42.55	9.00e-74	272.00
IUUC-Stu-112899	Solanum tuberosum	42.01	5.00e-73	270.00
IUUC-Sar-112986	Sorex araneus	85.51	0.00e+00	2427.00
IUUC-Sbi-114604	Sorghum bicolor	40.32	7.00e-68	253.00
IUUC-Sre-115191	Sporisorium reilianum	42.90	3.00e-67	251.00
IUUC-Ssc-115440	Sus scrofa	85.22	0.00e+00	2403.00
IUUC-Tgu-116633	Taeniopygia guttata	87.13	0.00e+00	2503.00
IUUC-Tru-118439	Takifugu rubripes	78.02	0.00e+00	2247.00
IUUC-Tsy-119472	Tarsius syrichta	78.81	0.00e+00	1263.00
IUUC-Tni-119808	Tetraodon nigroviridis	73.37	0.00e+00	2032.00
IUUC-Tca-121648	Theobroma cacao	42.89	2.00e-75	278.00
IUUC-Tre-122161	Trichoderma reesei	34.32	2.00e-124	440.00
IUUC-Tvi-122575	Trichoderma virens	33.41	9.00e-116	412.00
IUUC-Tae-123381	Triticum aestivum	47.30	2.00e-67	251.00
IUUC-Tur-126291	Triticum urartu	44.14	1.00e-67	252.00
IUUC-Tme-126979	Tuber melanosporum	37.92	8.00e-153	535.00
IUUC-Tbe-127576	Tupaia belangeri	74.96	0.00e+00	860.00
IUUC-Ttr-129106	Tursiops truncatus	90.17	0.00e+00	1226.00
IUUC-Uma-129633	Ustilago maydis	42.50	3.00e-75	278.00
IUUC-Vda-130001	Verticillium dahliae	45.13	8.00e-77	282.00
IUUC-Vpa-130733	Vicugna pacos	78.28	0.00e+00	1153.00
IUUC-Vvi-131318	Vitis vinifera	42.40	3.00e-72	267.00
IUUC-Xma-133331	Xiphophorus maculatus	79.39	0.00e+00	2253.00
IUUC-Yli-134651	Yarrowia lipolytica	37.14	1.00e-121	431.00
IUUC-Zma-135850	Zea mays	40.05	1.00e-67	251.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence