iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-021496

Ensembl Protein ID

ENSCPOP00000003231.2

UniProt Accession

H0V172; H0V172_CAVPO

Genbank Protein ID

ENSCPOP00000003231

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02044032

Gene Name

LATS1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000003577.3	ENSCPOT00000003621.2	ENSCPOP00000003231.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	1.40e-06	28.2	103	140

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraa.nnnleaAveyLl 39
           + ++ + l++ GFd++ ++qaL+ + n ++eaA+e++ 
   Q: 103  NPQMFQDLQAAGFDEDMVIQALQKTnNRSIEAAIEFIS 140
           67899*******************99*********975 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MKRSEKPEGY RQMRPKTFPA SNYTGSSRQM LQEIRESLRN LSKPSDAAKA EHNMTKMSTE 60
DARQVRNPPK FGTYHKALQE IRNSLQPFAN ETSSSSRITS EVNPQMFQDL QAAGFDEDMV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAGAGGA GTGAAAAGCC AGAAGGATAT AGACAAATGA GGCCTAAGAC CTTCCCTGCC 60
AGTAACTACA CTGGCAGCAG TCGGCAAATG TTGCAAGAAA TTCGGGAATC CCTTAGGAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011009--Kinase-like_dom
IPR028741--LATS1/Warts
IPR000719--Prot_kinase_dom
IPR008271--Ser/Thr_kinase_AS
IPR015940--UBA
IPR009060--UBA-like

PROSITE

PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50030--UBA

Pfam

PF00069--Pkinase
PF00627--UBA

SMART

SM00220--S_TKc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0000922--C:spindle pole
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0051220--P:cytoplasmic sequestering of protein
GO:0000086--P:G2/M transition of mitotic cell cycle
GO:0035329--P:hippo signaling
GO:0009755--P:hormone-mediated signaling pathway
GO:0001827--P:inner cell mass cell fate commitment
GO:0001828--P:inner cell mass cellular morphogenesis
GO:0030216--P:keratinocyte differentiation
GO:0060644--P:mammary gland epithelial cell differentiation
GO:0007067--P:mitotic nuclear division
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:0045736--P:negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0033138--P:positive regulation of peptidyl-serine phosphorylation
GO:0030833--P:regulation of actin filament polymerization
GO:0033146--P:regulation of intracellular estrogen receptor signaling pathway
GO:2000058--P:regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0000819--P:sister chromatid segregation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001895	Ailuropoda melanoleuca	93.05	0.00e+00	1653.00
IUUC-Apl-003278	Anas platyrhynchos	81.53	0.00e+00	1469.00
IUUC-Aca-005319	Anolis carolinensis	79.67	0.00e+00	1415.00
IUUC-Ame-011324	Astyanax mexicanus	65.27	0.00e+00	1063.00
IUUC-Bta-013438	Bos taurus	91.60	0.00e+00	1586.00
IUUC-Cja-019072	Callithrix jacchus	91.38	0.00e+00	1662.00
IUUC-Cfa-021267	Canis familiaris	92.73	0.00e+00	1672.00
IUUC-Csa-023255	Chlorocebus sabaeus	92.43	0.00e+00	1632.00
IUUC-Cho-024461	Choloepus hoffmanni	97.87	0.00e+00	789.00
IUUC-Dre-028034	Danio rerio	59.33	0.00e+00	985.00
IUUC-Dno-029888	Dasypus novemcinctus	89.00	0.00e+00	1620.00
IUUC-Dor-030144	Dipodomys ordii	79.96	0.00e+00	1360.00
IUUC-Ete-032813	Echinops telfairi	93.04	0.00e+00	911.00
IUUC-Eca-033781	Equus caballus	92.53	0.00e+00	1627.00
IUUC-Eeu-035007	Erinaceus europaeus	88.89	0.00e+00	1592.00
IUUC-Fca-036142	Felis catus	85.57	0.00e+00	1533.00
IUUC-Fal-036626	Ficedula albicollis	81.32	0.00e+00	1481.00
IUUC-Gga-040553	Gallus gallus	81.03	0.00e+00	1483.00
IUUC-Gac-042031	Gasterosteus aculeatus	63.14	0.00e+00	1028.00
IUUC-Ggo-045242	Gorilla gorilla	92.44	0.00e+00	1642.00
IUUC-Hsa-046081	Homo sapiens	92.53	0.00e+00	1642.00
IUUC-Itr-048668	Ictidomys tridecemlineatus	92.62	0.00e+00	1360.00
IUUC-Lch-049425	Latimeria chalumnae	78.40	0.00e+00	1056.00
IUUC-Loc-052418	Lepisosteus oculatus	66.70	0.00e+00	1098.00
IUUC-Laf-053710	Loxodonta africana	92.02	0.00e+00	1616.00
IUUC-Mcc-055079	Macaca mulatta	92.43	0.00e+00	1630.00
IUUC-Mga-059713	Meleagris gallopavo	80.86	0.00e+00	1486.00
IUUC-Mmr-061728	Microcebus murinus	93.46	0.00e+00	1646.00
IUUC-Mdo-061942	Monodelphis domestica	85.43	0.00e+00	1494.00
IUUC-Mmu-063504	Mus musculus	89.62	0.00e+00	1581.00
IUUC-Mpu-066034	Mustela putorius furo	92.52	0.00e+00	1642.00
IUUC-Mlu-067986	Myotis lucifugus	92.00	0.00e+00	1644.00
IUUC-Nle-069202	Nomascus leucogenys	92.43	0.00e+00	1641.00
IUUC-Opr-070801	Ochotona princeps	94.34	0.00e+00	938.00
IUUC-Ont-072487	Oreochromis niloticus	58.76	0.00e+00	962.00
IUUC-Oan-073128	Ornithorhynchus anatinus	83.64	0.00e+00	1296.00
IUUC-Ocu-073998	Oryctolagus cuniculus	93.99	0.00e+00	1089.00
IUUC-Ola-086858	Oryzias latipes	59.21	0.00e+00	941.00
IUUC-Oga-088874	Otolemur garnettii	90.89	0.00e+00	1586.00
IUUC-Oar-089236	Ovis aries	91.71	0.00e+00	1599.00
IUUC-Ptr-091425	Pan troglodytes	92.74	0.00e+00	1649.00
IUUC-Pan-091851	Papio anubis	92.55	0.00e+00	1634.00
IUUC-Psi-093825	Pelodiscus sinensis	83.33	0.00e+00	1467.00
IUUC-Pfo-096326	Poecilia formosa	59.40	0.00e+00	946.00
IUUC-Pab-097815	Pongo abelii	92.53	0.00e+00	1644.00
IUUC-Pva-102836	Pteropus vampyrus	90.66	0.00e+00	1542.00
IUUC-Rno-106053	Rattus norvegicus	90.15	0.00e+00	1602.00
IUUC-Sha-106843	Sarcophilus harrisii	86.97	0.00e+00	1534.00
IUUC-Sar-113649	Sorex araneus	90.91	0.00e+00	1169.00
IUUC-Ssc-115486	Sus scrofa	96.43	0.00e+00	851.00
IUUC-Tgu-116903	Taeniopygia guttata	80.60	0.00e+00	1461.00
IUUC-Tru-118760	Takifugu rubripes	63.01	0.00e+00	1029.00
IUUC-Tsy-119361	Tarsius syrichta	91.04	0.00e+00	1368.00
IUUC-Tni-120058	Tetraodon nigroviridis	57.89	0.00e+00	927.00
IUUC-Tbe-127681	Tupaia belangeri	94.26	0.00e+00	1216.00
IUUC-Ttr-128652	Tursiops truncatus	91.90	0.00e+00	1623.00
IUUC-Vpa-130538	Vicugna pacos	91.49	0.00e+00	1600.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence