iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-061942

Ensembl Protein ID

ENSMODP00000020983.4

UniProt Accession

F7FV88; F7FV88_MONDO

Protein Name

Uncharacterized protein

Gene Name

LATS1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000016812.4	ENSMODT00000021353.4	ENSMODP00000020983.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	1.10e-07	31.9	117	154

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraa.nnnleaAveyLl 39
           + ++l+ ++  GFd++ +++aLr++ n+++eaA+e++ 
   Q: 117  NRQMLQDMQIAGFDEDMVIRALRQTnNKSIEAAIEFIS 154
           569*********************99*********975 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MSESSVKVIQ IDVFMKRSEK PEGYRQMRPK TFPASNYTGS SRQMLQEIRE SLRNLPKPSD 60
AAKAEHSMNK ATIEDPRQGR NPPKFVTYHK ALQEIRNSLL PFANEASSST RSASEVNRQM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGCCTTCCG AGGAGTTGGT CAGCGCGCAC GGAGAAGAAC CGAGGAAAAG CCCCAAGTTC 60
TTACCCCCGC CCTTTTCTTC ACCCTCCCCT CTCTTCTCCT CTCCTCTCCT CTCTTCCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011009--Kinase-like_dom
IPR028741--LATS1/Warts
IPR000719--Prot_kinase_dom
IPR008271--Ser/Thr_kinase_AS
IPR015940--UBA
IPR009060--UBA-like

PROSITE

PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50030--UBA

Pfam

PF00069--Pkinase
PF00627--UBA

SMART

SM00220--S_TKc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0000922--C:spindle pole
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0051220--P:cytoplasmic sequestering of protein
GO:0000082--P:G1/S transition of mitotic cell cycle
GO:0000086--P:G2/M transition of mitotic cell cycle
GO:0035329--P:hippo signaling
GO:0009755--P:hormone-mediated signaling pathway
GO:0001827--P:inner cell mass cell fate commitment
GO:0001828--P:inner cell mass cellular morphogenesis
GO:0030216--P:keratinocyte differentiation
GO:0060644--P:mammary gland epithelial cell differentiation
GO:0007067--P:mitotic nuclear division
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:0045736--P:negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0018105--P:peptidyl-serine phosphorylation
GO:0043065--P:positive regulation of apoptotic process
GO:0033138--P:positive regulation of peptidyl-serine phosphorylation
GO:0030833--P:regulation of actin filament polymerization
GO:0033146--P:regulation of intracellular estrogen receptor signaling pathway
GO:0046620--P:regulation of organ growth
GO:2000058--P:regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0000819--P:sister chromatid segregation

KEGG

mdo:100026943

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001895	Ailuropoda melanoleuca	87.96	0.00e+00	1838.00
IUUC-Apl-003278	Anas platyrhynchos	83.36	0.00e+00	1785.00
IUUC-Aca-005319	Anolis carolinensis	82.72	0.00e+00	1731.00
IUUC-Ame-011324	Astyanax mexicanus	84.93	0.00e+00	940.00
IUUC-Bta-013438	Bos taurus	86.99	0.00e+00	1786.00
IUUC-Cel-018517	Caenorhabditis elegans	50.11	1.00e-128	454.00
IUUC-Cja-019072	Callithrix jacchus	86.73	0.00e+00	1846.00
IUUC-Cfa-021267	Canis familiaris	87.52	0.00e+00	1840.00
IUUC-Cpo-021496	Cavia porcellus	84.09	0.00e+00	1545.00
IUUC-Csa-023255	Chlorocebus sabaeus	87.96	0.00e+00	1839.00
IUUC-Cho-024461	Choloepus hoffmanni	96.79	0.00e+00	778.00
IUUC-Cin-025264	Ciona intestinalis	65.58	4.00e-141	494.00
IUUC-Dre-028034	Danio rerio	84.57	0.00e+00	935.00
IUUC-Dno-029888	Dasypus novemcinctus	85.24	0.00e+00	1842.00
IUUC-Dor-030144	Dipodomys ordii	78.56	0.00e+00	1561.00
IUUC-Dme-031656	Drosophila melanogaster	73.19	0.00e+00	654.00
IUUC-Ete-032813	Echinops telfairi	90.98	0.00e+00	1193.00
IUUC-Eca-033781	Equus caballus	87.26	0.00e+00	1802.00
IUUC-Eeu-035007	Erinaceus europaeus	85.76	0.00e+00	1821.00
IUUC-Fca-036142	Felis catus	83.57	0.00e+00	1735.00
IUUC-Fal-036626	Ficedula albicollis	83.36	0.00e+00	1799.00
IUUC-Gmo-038688	Gadus morhua	86.46	0.00e+00	783.00
IUUC-Gga-040553	Gallus gallus	83.79	0.00e+00	1777.00
IUUC-Gac-042031	Gasterosteus aculeatus	63.50	0.00e+00	1258.00
IUUC-Ggo-045242	Gorilla gorilla	87.71	0.00e+00	1835.00
IUUC-Hsa-046081	Homo sapiens	87.52	0.00e+00	1830.00
IUUC-Itr-048668	Ictidomys tridecemlineatus	88.66	0.00e+00	1582.00
IUUC-Lch-049425	Latimeria chalumnae	77.60	0.00e+00	1660.00
IUUC-Loc-052418	Lepisosteus oculatus	66.64	0.00e+00	1356.00
IUUC-Laf-053710	Loxodonta africana	87.09	0.00e+00	1826.00
IUUC-Mcc-055079	Macaca mulatta	87.79	0.00e+00	1831.00
IUUC-Mga-059713	Meleagris gallopavo	83.03	0.00e+00	1788.00
IUUC-Mmr-061728	Microcebus murinus	87.79	0.00e+00	1848.00
IUUC-Mmu-063504	Mus musculus	85.76	0.00e+00	1768.00
IUUC-Mpu-066034	Mustela putorius furo	87.61	0.00e+00	1827.00
IUUC-Mlu-067986	Myotis lucifugus	86.12	0.00e+00	1811.00
IUUC-Nle-069202	Nomascus leucogenys	87.52	0.00e+00	1831.00
IUUC-Opr-070801	Ochotona princeps	91.80	0.00e+00	1244.00
IUUC-Ont-072487	Oreochromis niloticus	61.42	0.00e+00	1196.00
IUUC-Oan-073128	Ornithorhynchus anatinus	87.01	0.00e+00	1602.00
IUUC-Ocu-073998	Oryctolagus cuniculus	90.34	0.00e+00	1363.00
IUUC-Ola-086858	Oryzias latipes	60.92	0.00e+00	1179.00
IUUC-Oga-088874	Otolemur garnettii	85.78	0.00e+00	1771.00
IUUC-Oar-089236	Ovis aries	87.01	0.00e+00	1788.00
IUUC-Ptr-091425	Pan troglodytes	87.70	0.00e+00	1833.00
IUUC-Pan-091851	Papio anubis	87.97	0.00e+00	1840.00
IUUC-Psi-093825	Pelodiscus sinensis	86.13	0.00e+00	1499.00
IUUC-Pfo-096326	Poecilia formosa	61.47	0.00e+00	1186.00
IUUC-Pab-097815	Pongo abelii	87.70	0.00e+00	1835.00
IUUC-Pva-102836	Pteropus vampyrus	86.20	0.00e+00	1734.00
IUUC-Ptt-103762	Puccinia triticina	37.93	6.00e-93	335.00
IUUC-Rno-106053	Rattus norvegicus	86.20	0.00e+00	1802.00
IUUC-Sha-106843	Sarcophilus harrisii	96.57	0.00e+00	2021.00
IUUC-Sar-113649	Sorex araneus	87.24	0.00e+00	1449.00
IUUC-Ssc-115486	Sus scrofa	95.71	0.00e+00	843.00
IUUC-Tgu-116903	Taeniopygia guttata	83.71	0.00e+00	1787.00
IUUC-Tru-118760	Takifugu rubripes	63.40	0.00e+00	1285.00
IUUC-Tsy-119361	Tarsius syrichta	86.97	0.00e+00	1579.00
IUUC-Tni-120058	Tetraodon nigroviridis	58.69	0.00e+00	1135.00
IUUC-Tbe-127681	Tupaia belangeri	88.97	0.00e+00	1455.00
IUUC-Ttr-128652	Tursiops truncatus	86.98	0.00e+00	1514.00
IUUC-Vpa-130538	Vicugna pacos	86.91	0.00e+00	1800.00
IUUC-Xtr-132895	Xenopus tropicalis	71.19	0.00e+00	1274.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence