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Tag Content
UUCD2 ID IUUC-Sha-106569
UUCD1 version UUC-SaH-00055
Ensembl Protein ID ENSSHAP00000001219.1
UniProt Accession G3VDG5; G3VDG5_SARHA
Genbank Protein ID ENSSHAP00000001219
Protein Name Uncharacterized protein
Genbank Nucleotide ID AEFK01135560
Gene Name CUL3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSSHAG00000001088.1 ENSSHAT00000001234.1 ENSSHAP00000001219.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/Cullin 7.90e-213 708.7 3 581
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/Cullin
   S: 51   kqvkkkveesedeqlLktynreWekfreqlkvlrkifayldrtyvkkskkvsevrkLaldlwrkeived..ikkrllelllklieaeRk 137
            qv+++v +s ++++L+t+n++W++++++++++r+i++y+dr+yv++ ++v++v++L+l ++r+++v++  i+++l ++ll++i++eRk
   Q: 3    LQVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQ-NNVENVYNLGLIIFRDQVVRYgcIRDHLRQTLLDMIARERK 90
           5899*******************************************.***************************************** PP
   S: 138  geavdrrllsgvveslveLslnklaiykesFEakfleatqefykaesaeflqenevdeYlkkvearlneeeeraaryleestetkLlev 226
           ge+vdr  +++++++l+ L+l+ +++y+e+FEa+fle+++ef+++es++fl+en+ + Y+kkvear+nee er++++l++ste+++++v
   Q: 91   GEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKV 179
           ***************************************************************************************** PP
   S: 227  vekeliakhlesll....aelvallrdkktedlsrmykLlsrvlngleellkeleshikeqgkaaltaeekekdpkkyVerllelknkl 311
           ve+eli+kh+++++    ++lv++l++ ktedl++mykL+srv+ngl++++++++s+++eqgka++++e + k+p++y++ ll+lk+++
   Q: 180  VERELISKHMKTIVemenSGLVHMLKNGKTEDLACMYKLFSRVPNGLKTMCECMSSYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRF 268
           **************99999********************************************************************** PP
   S: 312  qklvseaFnndakFlkaldkafetfvnknsvlkaakspEllAryiDqlLrksskglteeeleaqldkvllvfkyisekdvFekyYkkhL 400
           +++++e+Fnnd+ F ++++ +fe+f+n n     ++spE+l+ +iD++L+k++kglte+e+e++ldk++++f++++ekdvFe+yYk+hL
   Q: 269  DRFLQESFNNDRLFKQTIAGDFEYFLNLN-----SRSPEYLSLFIDDKLKKGVKGLTEQEVETILDKAMVLFRFMQEKDVFERYYKQHL 352
           *****************************.....******************************************************* PP
   S: 401  akRLlsgksasseaEesviekLkeecgaeftskLerMfqdlkvSedlnrqFkeekentees.esvelsvlvLsagaWptasetekvsLP 488
           a+RLl++ks+s+++E+++i+kLk+ecg++ftskLe+Mf+d+++S++++++F+++ ++t  s  +v+l+v+vL++g+Wpt+s+t+k+++P
   Q: 353  ARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHLQATGVSlGGVDLTVRVLTTGYWPTQSATPKCNIP 441
           ***********************************************************99889************************* PP
   S: 489  aelektiekfeefYlekhsgRkLqWqhtlgraelkael......................kkgkyelqVstfQmavLLafnnsekvsve 555
           +  ++++e+f++fYl khsgR+L++qh++g+a+l+a++                      +++k++lqVstfQm++L++fnn+ek+++e
   Q: 442  PAPRHAFEIFRRFYLAKHSGRQLTLQHHMGSADLNATFygpvkkedgsevgvggaqvtgsNTRKHILQVSTFQMTILMLFNNREKYTFE 530
           ************************************************999999998888888************************** PP
   S: 556  elkkatelpeeeLrrtlqsLvssk..kqvlkkepeskeieeedlfsvNqef 604
           e++++t++pe+eL r+lqsL+++k  ++vl+kep+skeie++++f+vN++f
   Q: 531  EIQQETDIPERELVRALQSLACGKptQRVLTKEPKSKEIENGHMFTVNDQF 581
           *************************************************99 PP
   
Organism Sarcophilus harrisii
Protein Sequence
(Fasta)
LLLQVREDVL NSLNNNFLQT LNQAWNDHQT AMVMIRDILM YMDRVYVQQN NVENVYNLGL 60
IIFRDQVVRY GCIRDHLRQT LLDMIARERK GEVVDRGAIR NACQMLMILG LEGRSVYEED 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Sha-106569|E3,Cullin|Sarcophilus harrisii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TTATTTTGTG TATTAATTGT TCTTTACATC TTTATATGGC ATATTATAAA GTTCTTTGTT 60
AAATGTTTCT AGTCCTGTTA TGTTGTTATA GAGAAAAAAG AAGTCCTCTC AATTCCATCA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Sha-106569|E3,Cullin|Sarcophilus harrisii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom
PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2
Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8
SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8
Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0070062--C:extracellular exosome
GO:0000139--C:Golgi membrane
GO:0005634--C:nucleus
GO:0005827--C:polar microtubule
GO:0004842--F:ubiquitin-protein transferase activity
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0016477--P:cell migration
GO:0048208--P:COPII vesicle coating
GO:0040016--P:embryonic cleavage
GO:0044346--P:fibroblast apoptotic process
GO:0007369--P:gastrulation
GO:0007229--P:integrin-mediated signaling pathway
GO:0072576--P:liver morphogenesis
GO:0007080--P:mitotic metaphase plate congression
GO:0035024--P:negative regulation of Rho protein signal transduction
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0032467--P:positive regulation of cytokinesis
GO:0045842--P:positive regulation of mitotic metaphase/anaphase transition
GO:0006513--P:protein monoubiquitination
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0017145--P:stem cell division
GO:0043149--P:stress fiber assembly
GO:0001831--P:trophectodermal cellular morphogenesis
GO:0071630--P:ubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome
GO:0016055--P:Wnt signaling pathway
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000335 Aegilops tauschii 50.97 0.00e+00 656.00
IUUC-Aml-002278 Ailuropoda melanoleuca 98.84 0.00e+00 1381.00
IUUC-Atr-002616 Amborella trichopoda 53.14 0.00e+00 699.00
IUUC-Apl-004172 Anas platyrhynchos 99.27 0.00e+00 1384.00
IUUC-Aca-004309 Anolis carolinensis 99.27 0.00e+00 1385.00
IUUC-Aly-005566 Arabidopsis lyrata 52.69 0.00e+00 699.00
IUUC-Ath-007587 Arabidopsis thaliana 53.13 0.00e+00 704.00
IUUC-Acl-008317 Aspergillus clavatus 37.74 2.00e-132 466.00
IUUC-Afl-008727 Aspergillus flavus 37.76 1.00e-134 474.00
IUUC-Afu-008879 Aspergillus fumigatus 37.96 5.00e-133 468.00
IUUC-Ani-009393 Aspergillus nidulans 37.02 6.00e-127 448.00
IUUC-Ang-009626 Aspergillus niger 38.07 1.00e-133 470.00
IUUC-Aor-010207 Aspergillus oryzae 37.76 1.00e-134 473.00
IUUC-Ate-010305 Aspergillus terreus 38.21 1.00e-129 457.00
IUUC-Ame-011805 Astyanax mexicanus 97.22 0.00e+00 1355.00
IUUC-Bgr-012098 Blumeria graminis 36.11 9.00e-110 391.00
IUUC-Bta-013445 Bos taurus 99.42 0.00e+00 1387.00
IUUC-Bci-013612 Botrytis cinerea 37.14 2.00e-126 446.00
IUUC-Bdi-014269 Brachypodium distachyon 53.81 0.00e+00 676.00
IUUC-Bol-015350 Brassica oleracea 53.21 0.00e+00 701.00
IUUC-Bra-016763 Brassica rapa 53.36 0.00e+00 704.00
IUUC-Cel-018641 Caenorhabditis elegans 46.55 2.00e-178 619.00
IUUC-Cja-019175 Callithrix jacchus 99.27 0.00e+00 1383.00
IUUC-Cfa-020905 Canis familiaris 99.42 0.00e+00 1385.00
IUUC-Cpo-021293 Cavia porcellus 99.27 0.00e+00 1383.00
IUUC-Cre-022776 Chlamydomonas reinhardtii 48.74 1.00e-179 623.00
IUUC-Csa-023800 Chlorocebus sabaeus 99.12 0.00e+00 1381.00
IUUC-Cho-024839 Choloepus hoffmanni 98.82 0.00e+00 1353.00
IUUC-Cin-025201 Ciona intestinalis 69.70 0.00e+00 888.00
IUUC-Csv-026107 Ciona savignyi 69.78 0.00e+00 979.00
IUUC-Cgl-026630 Colletotrichum gloeosporioides 36.00 1.00e-114 407.00
IUUC-Cne-027048 Cryptococcus neoformans 35.08 1.00e-103 370.00
IUUC-Cme-027254 Cyanidioschyzon merolae 30.23 1.00e-75 277.00
IUUC-Dre-028488 Danio rerio 97.37 0.00e+00 1358.00
IUUC-Dno-029784 Dasypus novemcinctus 99.42 0.00e+00 1386.00
IUUC-Dor-030682 Dipodomys ordii 91.37 0.00e+00 1230.00
IUUC-Dse-031326 Dothistroma septosporum 36.03 4.00e-116 412.00
IUUC-Dme-032112 Drosophila melanogaster 68.70 0.00e+00 971.00
IUUC-Ete-032347 Echinops telfairi 86.62 0.00e+00 1151.00
IUUC-Eca-033560 Equus caballus 99.42 0.00e+00 1385.00
IUUC-Eeu-034502 Erinaceus europaeus 97.79 0.00e+00 1344.00
IUUC-Fca-035544 Felis catus 99.42 0.00e+00 1385.00
IUUC-Fal-036751 Ficedula albicollis 99.42 0.00e+00 1386.00
IUUC-Fox-037857 Fusarium oxysporum 36.91 6.00e-124 438.00
IUUC-Fso-038163 Fusarium solani 36.83 3.00e-127 449.00
IUUC-Gmo-039270 Gadus morhua 96.81 0.00e+00 1360.00
IUUC-Ggr-039999 Gaeumannomyces graminis 34.56 2.00e-117 416.00
IUUC-Gga-040329 Gallus gallus 99.27 0.00e+00 1386.00
IUUC-Gac-041510 Gasterosteus aculeatus 97.08 0.00e+00 1358.00
IUUC-Gma-043182 Glycine max 52.24 0.00e+00 672.00
IUUC-Ggo-044903 Gorilla gorilla 98.98 0.00e+00 1376.00
IUUC-Hsa-046000 Homo sapiens 99.12 0.00e+00 1381.00
IUUC-Hvu-047831 Hordeum vulgare 53.21 0.00e+00 673.00
IUUC-Itr-049067 Ictidomys tridecemlineatus 99.78 0.00e+00 940.00
IUUC-Kpa-049372 Komagataella pastoris 34.58 1.00e-101 363.00
IUUC-Lch-050458 Latimeria chalumnae 98.98 0.00e+00 1379.00
IUUC-Lpe-051396 Leersia perrieri 53.21 0.00e+00 690.00
IUUC-Loc-052186 Lepisosteus oculatus 98.83 0.00e+00 1383.00
IUUC-Lma-053030 Leptosphaeria maculans 39.70 4.00e-133 468.00
IUUC-Laf-053684 Loxodonta africana 99.42 0.00e+00 1385.00
IUUC-Mcc-055770 Macaca mulatta 99.12 0.00e+00 1381.00
IUUC-Meu-056852 Macropus eugenii 99.73 0.00e+00 762.00
IUUC-Mor-057273 Magnaporthe oryzae 35.05 6.00e-122 431.00
IUUC-Mpo-057403 Magnaporthe poae 34.56 3.00e-119 422.00
IUUC-Mtr-058317 Medicago truncatula 52.69 0.00e+00 679.00
IUUC-Mla-059055 Melampsora laricipopulina 36.96 7.00e-119 421.00
IUUC-Mga-060076 Meleagris gallopavo 97.51 0.00e+00 1352.00
IUUC-Mvi-060470 Microbotryum violaceum 33.67 7.00e-124 438.00
IUUC-Mmr-060976 Microcebus murinus 99.42 0.00e+00 1387.00
IUUC-Mdo-062741 Monodelphis domestica 99.42 0.00e+00 1387.00
IUUC-Mmu-063905 Mus musculus 99.12 0.00e+00 1382.00
IUUC-Mac-064718 Musa acuminata 51.80 0.00e+00 660.00
IUUC-Mpu-066356 Mustela putorius furo 99.42 0.00e+00 1385.00
IUUC-Mlu-067768 Myotis lucifugus 98.84 0.00e+00 1380.00
IUUC-Nfi-068285 Neosartorya fischeri 38.10 7.00e-134 471.00
IUUC-Ncr-068883 Neurospora crassa 37.67 3.00e-129 456.00
IUUC-Nle-069638 Nomascus leucogenys 99.12 0.00e+00 1381.00
IUUC-Opr-070333 Ochotona princeps 89.70 0.00e+00 1147.00
IUUC-Ont-071601 Oreochromis niloticus 97.95 0.00e+00 1403.00
IUUC-Oan-073281 Ornithorhynchus anatinus 99.68 0.00e+00 1300.00
IUUC-Ocu-074504 Oryctolagus cuniculus 99.42 0.00e+00 1385.00
IUUC-Oba-075332 Oryza barthii 53.70 0.00e+00 682.00
IUUC-Obr-076435 Oryza brachyantha 53.96 0.00e+00 693.00
IUUC-Ogl-077655 Oryza glaberrima 53.66 0.00e+00 691.00
IUUC-Ogu-078458 Oryza glumaepatula 53.70 0.00e+00 681.00
IUUC-Oin-079567 Oryza indica 53.66 0.00e+00 692.00
IUUC-Olo-080930 Oryza longistaminata 53.66 0.00e+00 692.00
IUUC-Ome-081353 Oryza meridionalis 53.66 0.00e+00 691.00
IUUC-Oni-082378 Oryza nivara 53.66 0.00e+00 691.00
IUUC-Opu-084055 Oryza punctata 53.66 0.00e+00 692.00
IUUC-Oru-084202 Oryza rufipogon 53.70 0.00e+00 681.00
IUUC-Osa-085290 Oryza sativa 53.66 0.00e+00 692.00
IUUC-Ola-087562 Oryzias latipes 97.66 0.00e+00 1367.00
IUUC-Olu-087866 Ostreococcus lucimarinus 37.85 5.00e-129 455.00
IUUC-Oga-088833 Otolemur garnettii 99.42 0.00e+00 1385.00
IUUC-Oar-089958 Ovis aries 99.42 0.00e+00 1385.00
IUUC-Ptr-091013 Pan troglodytes 99.12 0.00e+00 1381.00
IUUC-Pan-091796 Papio anubis 98.40 0.00e+00 1371.00
IUUC-Psi-093564 Pelodiscus sinensis 97.51 0.00e+00 1350.00
IUUC-Pno-094939 Phaeosphaeria nodorum 39.08 2.00e-127 449.00
IUUC-Ppa-095920 Physcomitrella patens 52.54 0.00e+00 690.00
IUUC-Pfo-097498 Poecilia formosa 93.04 0.00e+00 1350.00
IUUC-Pab-098164 Pongo abelii 99.12 0.00e+00 1381.00
IUUC-Pop-099497 Populus trichocarpa 53.36 0.00e+00 714.00
IUUC-Pca-100702 Procavia capensis 90.35 0.00e+00 1212.00
IUUC-Ppe-101971 Prunus persica 52.84 0.00e+00 666.00
IUUC-Pva-103129 Pteropus vampyrus 99.42 0.00e+00 1387.00
IUUC-Pgr-103684 Puccinia graminis 36.44 2.00e-110 393.00
IUUC-Ptt-103961 Puccinia triticina 36.62 1.00e-109 390.00
IUUC-Pte-104325 Pyrenophora teres 38.87 3.00e-124 439.00
IUUC-Pyt-104746 Pyrenophora triticirepentis 37.80 4.00e-122 432.00
IUUC-Rno-105935 Rattus norvegicus 99.27 0.00e+00 1383.00
IUUC-Sja-107676 Schizosaccharomyces japonicus 38.64 7.00e-137 481.00
IUUC-Spo-108135 Schizosaccharomyces pombe 38.49 6.00e-125 441.00
IUUC-Smo-109555 Selaginella moellendorffii 53.59 0.00e+00 713.00
IUUC-Sit-110763 Setaria italica 54.41 0.00e+00 692.00
IUUC-Sly-111090 Solanum lycopersicum 52.77 0.00e+00 692.00
IUUC-Stu-112351 Solanum tuberosum 52.91 0.00e+00 694.00
IUUC-Sar-113144 Sorex araneus 99.38 0.00e+00 984.00
IUUC-Sbi-114690 Sorghum bicolor 53.51 0.00e+00 694.00
IUUC-Sre-115005 Sporisorium reilianum 38.04 3.00e-135 476.00
IUUC-Ssc-116053 Sus scrofa 99.64 0.00e+00 1141.00
IUUC-Tgu-116523 Taeniopygia guttata 99.42 0.00e+00 1385.00
IUUC-Tru-118189 Takifugu rubripes 93.27 0.00e+00 1274.00
IUUC-Tsy-118962 Tarsius syrichta 92.65 0.00e+00 1253.00
IUUC-Tni-120614 Tetraodon nigroviridis 58.94 0.00e+00 812.00
IUUC-Tca-121282 Theobroma cacao 53.51 0.00e+00 697.00
IUUC-Tre-122201 Trichoderma reesei 36.15 1.00e-122 433.00
IUUC-Tvi-122321 Trichoderma virens 36.80 1.00e-122 434.00
IUUC-Tae-124292 Triticum aestivum 53.21 0.00e+00 674.00
IUUC-Tur-126800 Triticum urartu 53.06 0.00e+00 672.00
IUUC-Tme-127053 Tuber melanosporum 39.91 6.00e-140 491.00
IUUC-Tbe-127427 Tupaia belangeri 88.70 0.00e+00 1044.00
IUUC-Ttr-128662 Tursiops truncatus 97.37 0.00e+00 1345.00
IUUC-Uma-129597 Ustilago maydis 38.54 6.00e-135 474.00
IUUC-Vda-129726 Verticillium dahliae 35.72 2.00e-123 436.00
IUUC-Vpa-130809 Vicugna pacos 99.03 0.00e+00 646.00
IUUC-Vvi-131194 Vitis vinifera 53.06 0.00e+00 693.00
IUUC-Xtr-131887 Xenopus tropicalis 98.54 0.00e+00 1372.00
IUUC-Xma-133517 Xiphophorus maculatus 97.81 0.00e+00 1369.00
IUUC-Yli-134576 Yarrowia lipolytica 33.71 4.00e-101 362.00
IUUC-Zma-135030 Zea mays 53.96 0.00e+00 699.00
Created Date 25-Jun-2017

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