iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Nle-069795

Ensembl Protein ID

ENSNLEP00000023776.1

UniProt Accession

M3ZAN9; M3ZAN9_NOMLE

Genbank Protein ID

ENSNLEP00000023776

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01015958

Gene Name

RNF144B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000001700.2	ENSNLET00000032154.1	ENSNLEP00000023776.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	2.10e-51	175.2	60	252

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpek..leeseikellveeelykryekllleevveadaal 88
           Ck+Cl+e+s +++t+l+eC+++fC++Clkqy++l+i+eg+ + i+cp++ c ++  l+e+ei++ lv  ++++ y++l++e++v+ d+ +
   Q: 60   CKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGCGSPITCPDMVCLNHgtLQEAEIAC-LVPVDQFQLYQRLKFEREVHLDPYR 148
           ***************************************************9988899******.6999********************* PP
   S: 89   kwcpapdCslvvllekea..eklevecekcgkefCveCkeewHeglsCkelkeklakteeekeeaeskelleanskkCpkCkvyiekneg 176
           +wcp +dC++v+ +++++  + + vec++c+ +fC++Ck++wH++ sC++ +  +  te   ++a   + +ea +k+Cp C+vyie+neg
   Q: 149  TWCPVADCQTVCPVASSDpgQPVLVECPSCHLKFCSCCKDAWHAEISCRDSQPIVLPTE---HRALFGTDAEAPIKQCPVCRVYIERNEG 235
           *************9998877899999*****************************9999...99************************** PP
   S: 177  CnhmtCakCkaefCwlC 193
           C++m+C++Ck++fCw+C
   Q: 236  CAQMMCKNCKHTFCWYC 252
           ***************** PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MWFSRTMHTR KCAKLHMYGL RRLKNAEDRL MGSAGRLHYL AMTAENPTPG DLAPAPLITC 60
KLCLCEQSLD KMTTLQECQC IFCTACLKQY MQLAIREGCG SPITCPDMVC LNHGTLQEAE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGGTTCA GCAGGACCAT GCACACCAGA AAATGTGCAA AACTTCATAT GTATGTACGT 60
GAATCTTTTG AAATGAAAGC TCATGGTTTG ATCATGGTCT CAGAGGGGGT TATGATTGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1

Pfam

PF01485--IBR

SMART

SM00647--IBR
SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0031966--C:mitochondrial membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001257	Ailuropoda melanoleuca	94.06	2.00e-171	594.00
IUUC-Atr-002709	Amborella trichopoda	28.14	5.00e-17	83.20
IUUC-Apl-004112	Anas platyrhynchos	81.85	7.00e-130	456.00
IUUC-Aca-004533	Anolis carolinensis	76.39	4.00e-138	483.00
IUUC-Bta-012641	Bos taurus	94.08	2.00e-169	587.00
IUUC-Cja-019626	Callithrix jacchus	83.17	1.00e-145	508.00
IUUC-Cfa-020702	Canis familiaris	95.05	3.00e-173	600.00
IUUC-Cpo-022147	Cavia porcellus	95.38	7.00e-171	592.00
IUUC-Csa-023473	Chlorocebus sabaeus	98.02	1.00e-178	618.00
IUUC-Cho-024298	Choloepus hoffmanni	90.66	9.00e-141	492.00
IUUC-Dre-028099	Danio rerio	65.41	1.00e-91	329.00
IUUC-Dno-029122	Dasypus novemcinctus	86.39	1.00e-160	558.00
IUUC-Dor-030669	Dipodomys ordii	95.71	1.00e-133	468.00
IUUC-Ete-033141	Echinops telfairi	80.20	4.00e-132	463.00
IUUC-Eca-034360	Equus caballus	97.03	1.00e-175	608.00
IUUC-Eeu-034538	Erinaceus europaeus	72.77	8.00e-85	306.00
IUUC-Fca-036055	Felis catus	93.40	3.00e-170	590.00
IUUC-Fal-037339	Ficedula albicollis	80.65	1.00e-132	465.00
IUUC-Gmo-038780	Gadus morhua	61.17	2.00e-86	311.00
IUUC-Gga-040256	Gallus gallus	79.72	2.00e-132	464.00
IUUC-Gac-042127	Gasterosteus aculeatus	62.24	2.00e-94	338.00
IUUC-Ggo-044867	Gorilla gorilla	99.34	5.00e-180	622.00
IUUC-Hsa-046928	Homo sapiens	99.67	2.00e-180	624.00
IUUC-Hvu-047484	Hordeum vulgare	29.67	2.00e-17	83.20
IUUC-Itr-048250	Ictidomys tridecemlineatus	96.89	5.00e-110	389.00
IUUC-Lch-050168	Latimeria chalumnae	73.44	3.00e-132	464.00
IUUC-Lpe-051649	Leersia perrieri	29.06	2.00e-16	81.30
IUUC-Loc-052150	Lepisosteus oculatus	60.93	3.00e-87	314.00
IUUC-Laf-053967	Loxodonta africana	94.72	8.00e-171	592.00
IUUC-Mcc-055898	Macaca mulatta	98.02	1.00e-178	618.00
IUUC-Meu-056628	Macropus eugenii	97.44	3.00e-43	168.00
IUUC-Mtr-057989	Medicago truncatula	26.76	4.00e-19	88.20
IUUC-Mga-059820	Meleagris gallopavo	78.65	1.00e-130	458.00
IUUC-Mmr-060680	Microcebus murinus	94.06	2.00e-170	590.00
IUUC-Mdo-062839	Monodelphis domestica	85.86	2.00e-154	538.00
IUUC-Mmu-063339	Mus musculus	87.79	1.00e-148	518.00
IUUC-Mac-065414	Musa acuminata	28.91	4.00e-20	92.00
IUUC-Mpu-065973	Mustela putorius furo	92.06	1.00e-175	608.00
IUUC-Mlu-067112	Myotis lucifugus	95.05	8.00e-164	569.00
IUUC-Opr-070390	Ochotona princeps	88.12	4.00e-154	536.00
IUUC-Ont-072329	Oreochromis niloticus	64.73	2.00e-90	325.00
IUUC-Oan-072980	Ornithorhynchus anatinus	77.92	3.00e-137	480.00
IUUC-Ocu-073845	Oryctolagus cuniculus	94.39	9.00e-171	592.00
IUUC-Ola-086872	Oryzias latipes	61.80	7.00e-86	310.00
IUUC-Oga-088954	Otolemur garnettii	95.05	3.00e-172	597.00
IUUC-Oar-089879	Ovis aries	94.74	3.00e-170	590.00
IUUC-Ptr-090685	Pan troglodytes	99.67	2.00e-180	624.00
IUUC-Pan-092086	Papio anubis	97.69	2.00e-178	617.00
IUUC-Psi-093481	Pelodiscus sinensis	81.52	2.00e-138	484.00
IUUC-Pfo-096065	Poecilia formosa	65.15	2.00e-92	331.00
IUUC-Pab-098031	Pongo abelii	99.01	5.00e-179	619.00
IUUC-Pca-100936	Procavia capensis	91.42	3.00e-165	573.00
IUUC-Pva-102864	Pteropus vampyrus	85.48	8.00e-150	522.00
IUUC-Rno-105503	Rattus norvegicus	87.79	2.00e-148	518.00
IUUC-Sha-107425	Sarcophilus harrisii	86.51	2.00e-155	541.00
IUUC-Stu-112736	Solanum tuberosum	27.83	4.00e-19	88.20
IUUC-Ssc-115458	Sus scrofa	93.16	6.00e-159	553.00
IUUC-Tgu-117226	Taeniopygia guttata	79.57	3.00e-132	464.00
IUUC-Tru-118362	Takifugu rubripes	65.04	9.00e-95	339.00
IUUC-Tsy-119255	Tarsius syrichta	96.37	1.00e-174	605.00
IUUC-Tni-120140	Tetraodon nigroviridis	61.73	2.00e-88	318.00
IUUC-Tae-124420	Triticum aestivum	31.31	2.00e-18	87.00
IUUC-Tbe-127306	Tupaia belangeri	94.72	7.00e-171	592.00
IUUC-Ttr-128923	Tursiops truncatus	94.74	1.00e-158	551.00
IUUC-Vpa-130148	Vicugna pacos	94.39	3.00e-170	590.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence