iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000096304.2	ENSDART00000150896.2	ENSDARP00000126057.1
ENSDARG00000096304.2	ENSDART00000167596.1	ENSDARP00000140115.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.10e-10	42.3	9	79
E3 activity/RING/RING	3.00e-08	34.9	13	53

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggk.tcPvtrqpl.teedlvPnltlrrliqawceen 72
           ee+ C+I l++++dPv++p+G+ + r+++ ++  + ++  cP++++++ ++ dl+ n++lr+++++  +e+
   Q: 9    EELQCSICLDVFTDPVTTPCGHNFCRTCLDQYWTNTHTcCCPICKEKFsKQPDLKVNIALREVVEHLKQES 79
           799****************************999999989********78889**********99876665 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCl+ f d p+++pCgH f+++Cl q w         +  CP+C+
   Q: 13   CSICLDVFTD-PVTTPCGHNFCRTCLdQYW-----TNTHTCCCPICK 53
           **********.9**************7777.....45555689***6 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MVSSCGLNEE LQCSICLDVF TDPVTTPCGH NFCRTCLDQY WTNTHTCCCP ICKEKFSKQP 60
DLKVNIALRE VVEHLKQESR PAESEQTMED RLKKIQEINH SEDPNKTAAV SRSLLLPFQT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GACGTCATTG AACTAAAGAC GGAAAGTGAA AGAAAACTGC AGAGAAAGCA GAAGCAGAAA 60
TCAGACAAAA CCTTCCTGTA TCTGGAGAAC ACCGCGGATA TTCACTCACA GGTAAGTTTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR003613--Ubox_domain
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF13445--zf-RING_UBOX

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00589--PRY
SM00184--RING
SM00449--SPRY
SM00504--Ubox

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Meu-056885	Macropus eugenii	33.66	2.00e-32	132.00
IUUC-Opr-071178	Ochotona princeps	48.90	2.00e-48	187.00
IUUC-Ont-071428	Oreochromis niloticus	49.71	9.00e-90	323.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence