iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-091119

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AACZ03039117

Gene Name

SH3RF2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000017369.5	ENSPTRT00000046209.4	ENSPTRP00000045666.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	5.30e-08	33.3	12	53
UBD/SH3	2.60e-30	104.2	383	437

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++C+e ++   +vlpC+H+f++ Clq++     ++ ke rCP Cr
   Q: 12   CPVCFEKLDVTAKVLPCQHTFCKPCLQRV----FKAHKELRCPECR 53
           ********88899****************....99**********8 PP

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           + + +l++y+a   deL l+kG+ v+v+  ++qd gWl+gv+  +g+ G+fP+n+v 
   Q: 383  NMFVALHSYSAHGPDELDLQKGEGVRVL-GKCQD-GWLRGVSLVTGRVGIFPNNYVI 437
           7889************************.77776.9*******************96 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MDDLTLLDLL ECPVCFEKLD VTAKVLPCQH TFCKPCLQRV FKAHKELRCP ECRTPVFSNI 60
EALPANLLLV RLLDGVRSGQ SSGRGGSFRR PGTMTLQDGR KSRTNPRRLQ ASPFRLVPNV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTGGTTAAA GTTTTCAAAG CAGTGGCAGC AGCGGCGCTT GGAGGAAAGG AAGCCGGTTG 60
GAGGGCGCAG CGCACCCCTG CTGCGCGGAG GAGGGGGCTG AGCTGAACTC AGCAGAAGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR011511--SH3_2
IPR001452--SH3_domain
IPR028511--SH3RF2
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50002--SH3
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9
PF13445--zf-RING_UBOX

PRINTS

PR00452--SH3DOMAIN

SMART

SM00184--RING
SM00326--SH3

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0008270--F:zinc ion binding
GO:0010923--P:negative regulation of phosphatase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001594	Ailuropoda melanoleuca	87.11	0.00e+00	1106.00
IUUC-Apl-003443	Anas platyrhynchos	60.34	2.00e-171	595.00
IUUC-Aca-004632	Anolis carolinensis	52.84	1.00e-172	599.00
IUUC-Bta-013400	Bos taurus	89.03	0.00e+00	1080.00
IUUC-Cel-018180	Caenorhabditis elegans	27.51	5.00e-23	103.00
IUUC-Cja-019686	Callithrix jacchus	81.92	0.00e+00	1029.00
IUUC-Cfa-020893	Canis familiaris	89.63	0.00e+00	1131.00
IUUC-Cpo-021638	Cavia porcellus	83.61	0.00e+00	1061.00
IUUC-Csa-023846	Chlorocebus sabaeus	96.38	0.00e+00	1228.00
IUUC-Cho-024609	Choloepus hoffmanni	85.79	6.00e-164	570.00
IUUC-Dno-028940	Dasypus novemcinctus	86.23	0.00e+00	1082.00
IUUC-Dor-030491	Dipodomys ordii	80.00	3.00e-135	475.00
IUUC-Dse-031414	Dothistroma septosporum	32.84	1.00e-07	52.40
IUUC-Ete-032513	Echinops telfairi	85.03	0.00e+00	1057.00
IUUC-Eca-034241	Equus caballus	90.30	0.00e+00	1155.00
IUUC-Eeu-034636	Erinaceus europaeus	81.58	0.00e+00	941.00
IUUC-Fca-035862	Felis catus	86.19	0.00e+00	1084.00
IUUC-Gga-040748	Gallus gallus	54.38	3.00e-147	515.00
IUUC-Ggo-045267	Gorilla gorilla	99.17	0.00e+00	1286.00
IUUC-Hsa-045761	Homo sapiens	99.17	0.00e+00	1283.00
IUUC-Itr-048226	Ictidomys tridecemlineatus	85.46	0.00e+00	1087.00
IUUC-Lch-050498	Latimeria chalumnae	45.37	2.00e-122	433.00
IUUC-Laf-054061	Loxodonta africana	79.19	0.00e+00	843.00
IUUC-Mcc-054746	Macaca mulatta	95.45	0.00e+00	1200.00
IUUC-Meu-056390	Macropus eugenii	60.37	4.00e-93	335.00
IUUC-Mmr-061390	Microcebus murinus	86.40	0.00e+00	929.00
IUUC-Mdo-062951	Monodelphis domestica	72.84	0.00e+00	962.00
IUUC-Mmu-063840	Mus musculus	80.44	0.00e+00	1023.00
IUUC-Mpu-065840	Mustela putorius furo	87.28	0.00e+00	1125.00
IUUC-Mlu-067378	Myotis lucifugus	84.48	0.00e+00	1052.00
IUUC-Nle-069535	Nomascus leucogenys	95.27	0.00e+00	1184.00
IUUC-Opr-070739	Ochotona princeps	83.38	0.00e+00	1037.00
IUUC-Oan-073468	Ornithorhynchus anatinus	66.80	0.00e+00	784.00
IUUC-Ocu-074343	Oryctolagus cuniculus	85.03	0.00e+00	1025.00
IUUC-Oga-088276	Otolemur garnettii	80.95	0.00e+00	1016.00
IUUC-Oar-090315	Ovis aries	86.93	0.00e+00	1067.00
IUUC-Pan-092158	Papio anubis	95.72	0.00e+00	895.00
IUUC-Psi-092959	Pelodiscus sinensis	58.65	0.00e+00	731.00
IUUC-Pab-097675	Pongo abelii	97.91	0.00e+00	1257.00
IUUC-Pca-101021	Procavia capensis	77.76	0.00e+00	951.00
IUUC-Pva-102619	Pteropus vampyrus	88.35	0.00e+00	1062.00
IUUC-Rno-105918	Rattus norvegicus	80.72	0.00e+00	1030.00
IUUC-Sha-107391	Sarcophilus harrisii	68.94	0.00e+00	874.00
IUUC-Sja-107661	Schizosaccharomyces japonicus	44.83	2.00e-10	60.10
IUUC-Sar-113148	Sorex araneus	80.46	0.00e+00	639.00
IUUC-Ssc-116219	Sus scrofa	82.71	2.00e-127	448.00
IUUC-Tgu-116584	Taeniopygia guttata	56.49	2.00e-109	389.00
IUUC-Tsy-118968	Tarsius syrichta	83.91	7.00e-165	573.00
IUUC-Tbe-128007	Tupaia belangeri	90.02	0.00e+00	816.00
IUUC-Ttr-128499	Tursiops truncatus	85.87	0.00e+00	1098.00
IUUC-Vpa-130075	Vicugna pacos	84.09	5.00e-81	295.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence