iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062757

UUCD1 version

UUC-MoD-00808

Ensembl Protein ID

ENSMODP00000018318.2

UniProt Accession

F7EPY2; F7EPY2_MONDO

Protein Name

Uncharacterized protein

Gene Name

WDR59

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000014658.2	ENSMODT00000018651.2	ENSMODP00000018318.2
ENSMODG00000014658.2	ENSMODT00000018653.1	ENSMODP00000018320.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-19	69.7	173	207

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd..tllvsGsdDgtikvWDlrtg 33
           H +++++l++ +d  ++l+++s D+++k WD+r+ 
   Q: 173  HLSKIHGLDWhPDseHILATSSQDNSVKFWDYRQP 207
           99*********6665778*************9876 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

QATAMSVDCL GQHAVLSGRR FLYIVNLDAP SEGHRKISRQ SKWDIGAVQW NPHDSYAHYF 60
AASSNQRVDL YKWKDGSGEV GTALQGHTRV ISDLDWAVFE PDLLVTSSVD TYIYIWDIKD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGCAACTG CAATGTCTGT AGATTGTCTT GGGCAGCACG CTGTGCTTTC TGGGTAAGTG 60
AGCTCCAAAG TTCTCCTGTT GTGCAATTTC TGGGAACAAG AGGTTTCTGA TCAAAGAAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR006575--RWD-domain
IPR016135--UBQ-conjugating_enzyme/RWD
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50908--RWD
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00591--RWD
SM00320--WD40

Gene Ontology

GO:0061700--C:GATOR2 complex
GO:0034198--P:cellular response to amino acid starvation
GO:0032008--P:positive regulation of TOR signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002149	Ailuropoda melanoleuca	92.88	0.00e+00	1825.00
IUUC-Apl-004021	Anas platyrhynchos	87.30	0.00e+00	1681.00
IUUC-Aca-004977	Anolis carolinensis	83.03	0.00e+00	1664.00
IUUC-Ago-007961	Ashbya gossypii	29.62	6.00e-56	213.00
IUUC-Acl-008161	Aspergillus clavatus	28.60	9.00e-56	213.00
IUUC-Afl-008686	Aspergillus flavus	28.17	1.00e-57	219.00
IUUC-Afu-008932	Aspergillus fumigatus	28.71	1.00e-56	215.00
IUUC-Ani-009493	Aspergillus nidulans	28.44	2.00e-59	224.00
IUUC-Ang-009876	Aspergillus niger	27.86	1.00e-57	219.00
IUUC-Aor-009926	Aspergillus oryzae	28.17	1.00e-57	219.00
IUUC-Ate-010274	Aspergillus terreus	27.16	3.00e-54	207.00
IUUC-Ame-011297	Astyanax mexicanus	69.00	0.00e+00	1389.00
IUUC-Bgr-012173	Blumeria graminis	31.66	3.00e-44	174.00
IUUC-Bta-013261	Bos taurus	92.98	0.00e+00	1841.00
IUUC-Bci-013971	Botrytis cinerea	33.74	3.00e-46	181.00
IUUC-Cja-019167	Callithrix jacchus	91.96	0.00e+00	1815.00
IUUC-Cfa-020287	Canis familiaris	92.57	0.00e+00	1819.00
IUUC-Cpo-022510	Cavia porcellus	89.96	0.00e+00	1750.00
IUUC-Csa-023474	Chlorocebus sabaeus	91.62	0.00e+00	1849.00
IUUC-Cho-024634	Choloepus hoffmanni	95.17	0.00e+00	744.00
IUUC-Cin-025642	Ciona intestinalis	31.96	4.00e-129	456.00
IUUC-Csv-025848	Ciona savignyi	44.66	1.00e-55	208.00
IUUC-Cgl-026531	Colletotrichum gloeosporioides	32.80	5.00e-45	177.00
IUUC-Cne-027088	Cryptococcus neoformans	32.93	4.00e-45	176.00
IUUC-Dre-028753	Danio rerio	70.07	0.00e+00	1360.00
IUUC-Dno-029733	Dasypus novemcinctus	91.87	0.00e+00	1807.00
IUUC-Dor-030781	Dipodomys ordii	91.43	0.00e+00	944.00
IUUC-Dme-031803	Drosophila melanogaster	33.50	7.00e-141	494.00
IUUC-Ete-032622	Echinops telfairi	84.87	0.00e+00	1616.00
IUUC-Eca-033344	Equus caballus	93.29	0.00e+00	1828.00
IUUC-Eeu-034523	Erinaceus europaeus	82.48	0.00e+00	1588.00
IUUC-Fca-035650	Felis catus	93.29	0.00e+00	1840.00
IUUC-Fal-037404	Ficedula albicollis	86.97	0.00e+00	1715.00
IUUC-Fox-037955	Fusarium oxysporum	32.34	2.00e-44	175.00
IUUC-Fso-038289	Fusarium solani	33.75	5.00e-47	183.00
IUUC-Gmo-038547	Gadus morhua	65.84	0.00e+00	1341.00
IUUC-Ggr-039858	Gaeumannomyces graminis	36.46	2.00e-43	171.00
IUUC-Gga-041030	Gallus gallus	87.17	0.00e+00	1696.00
IUUC-Gac-042581	Gasterosteus aculeatus	69.33	0.00e+00	1398.00
IUUC-Ggo-044641	Gorilla gorilla	93.18	0.00e+00	1843.00
IUUC-Hsa-046134	Homo sapiens	93.29	0.00e+00	1841.00
IUUC-Itr-048551	Ictidomys tridecemlineatus	94.84	0.00e+00	734.00
IUUC-Kpa-049091	Komagataella pastoris	32.71	4.00e-44	174.00
IUUC-Lch-050288	Latimeria chalumnae	73.89	0.00e+00	1438.00
IUUC-Loc-052802	Lepisosteus oculatus	71.97	0.00e+00	1442.00
IUUC-Lma-053296	Leptosphaeria maculans	32.59	4.00e-47	184.00
IUUC-Laf-053997	Loxodonta africana	91.62	0.00e+00	1862.00
IUUC-Mcc-055855	Macaca mulatta	93.39	0.00e+00	1829.00
IUUC-Meu-056898	Macropus eugenii	92.16	0.00e+00	731.00
IUUC-Mor-056913	Magnaporthe oryzae	35.69	2.00e-43	172.00
IUUC-Mpo-057612	Magnaporthe poae	37.18	1.00e-44	175.00
IUUC-Mla-059097	Melampsora laricipopulina	30.98	2.00e-47	185.00
IUUC-Mga-059218	Meleagris gallopavo	87.07	0.00e+00	1692.00
IUUC-Mvi-060251	Microbotryum violaceum	31.78	2.00e-46	181.00
IUUC-Mmr-061093	Microcebus murinus	89.71	0.00e+00	1766.00
IUUC-Mmu-063839	Mus musculus	90.32	0.00e+00	1837.00
IUUC-Mpu-065977	Mustela putorius furo	93.29	0.00e+00	1840.00
IUUC-Mlu-067460	Myotis lucifugus	93.29	0.00e+00	1838.00
IUUC-Nfi-068250	Neosartorya fischeri	34.57	2.00e-51	198.00
IUUC-Ncr-068710	Neurospora crassa	33.65	1.00e-45	179.00
IUUC-Nle-070011	Nomascus leucogenys	93.18	0.00e+00	1836.00
IUUC-Opr-070731	Ochotona princeps	85.96	0.00e+00	1653.00
IUUC-Ont-072165	Oreochromis niloticus	70.75	0.00e+00	1399.00
IUUC-Oan-072887	Ornithorhynchus anatinus	91.04	0.00e+00	1850.00
IUUC-Ocu-073926	Oryctolagus cuniculus	90.17	0.00e+00	1667.00
IUUC-Ola-087111	Oryzias latipes	65.64	0.00e+00	1309.00
IUUC-Oga-088850	Otolemur garnettii	92.98	0.00e+00	1831.00
IUUC-Oar-090291	Ovis aries	92.68	0.00e+00	1833.00
IUUC-Ptr-091044	Pan troglodytes	92.98	0.00e+00	1831.00
IUUC-Pan-092374	Papio anubis	91.42	0.00e+00	1843.00
IUUC-Psi-093170	Pelodiscus sinensis	56.74	0.00e+00	976.00
IUUC-Pma-094544	Petromyzon marinus	67.63	7.00e-172	596.00
IUUC-Pno-095068	Phaeosphaeria nodorum	30.77	4.00e-43	170.00
IUUC-Pfo-096480	Poecilia formosa	67.38	0.00e+00	1326.00
IUUC-Pab-098134	Pongo abelii	91.86	0.00e+00	1801.00
IUUC-Pca-100763	Procavia capensis	73.48	0.00e+00	947.00
IUUC-Pva-102544	Pteropus vampyrus	91.86	0.00e+00	1825.00
IUUC-Pgr-103257	Puccinia graminis	32.92	3.00e-50	194.00
IUUC-Ptt-103942	Puccinia triticina	32.15	9.00e-46	179.00
IUUC-Pte-104065	Pyrenophora teres	32.08	1.00e-44	175.00
IUUC-Rno-105468	Rattus norvegicus	87.78	0.00e+00	1662.00
IUUC-Sce-106356	Saccharomyces cerevisiae	27.38	6.00e-56	213.00
IUUC-Sha-106662	Sarcophilus harrisii	95.33	0.00e+00	1880.00
IUUC-Sja-107973	Schizosaccharomyces japonicus	27.78	8.00e-67	249.00
IUUC-Spo-108265	Schizosaccharomyces pombe	24.30	1.00e-63	239.00
IUUC-Ssl-108662	Sclerotinia sclerotiorum	34.35	1.00e-45	179.00
IUUC-Sar-113525	Sorex araneus	87.32	0.00e+00	1024.00
IUUC-Sre-115163	Sporisorium reilianum	37.45	3.00e-41	164.00
IUUC-Ssc-115381	Sus scrofa	89.98	0.00e+00	1002.00
IUUC-Tgu-116525	Taeniopygia guttata	83.52	0.00e+00	1620.00
IUUC-Tru-118432	Takifugu rubripes	67.69	0.00e+00	1369.00
IUUC-Tsy-119306	Tarsius syrichta	77.54	0.00e+00	1161.00
IUUC-Tni-120757	Tetraodon nigroviridis	67.46	0.00e+00	1335.00
IUUC-Tre-122187	Trichoderma reesei	35.35	2.00e-48	188.00
IUUC-Tvi-122367	Trichoderma virens	35.67	6.00e-48	186.00
IUUC-Tme-126986	Tuber melanosporum	26.70	2.00e-62	234.00
IUUC-Tbe-127800	Tupaia belangeri	76.03	0.00e+00	1279.00
IUUC-Ttr-129154	Tursiops truncatus	85.03	0.00e+00	1647.00
IUUC-Uma-129366	Ustilago maydis	36.36	3.00e-40	161.00
IUUC-Vda-129827	Verticillium dahliae	34.18	7.00e-48	186.00
IUUC-Vpa-130493	Vicugna pacos	92.97	0.00e+00	1818.00
IUUC-Xtr-131941	Xenopus tropicalis	79.45	0.00e+00	1550.00
IUUC-Xma-133903	Xiphophorus maculatus	68.84	0.00e+00	1371.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence