iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000004366.5	ENSGALT00000076311.1	ENSGALP00000048912.1
ENSGALG00000004366.5	ENSGALT00000006965.5	ENSGALP00000006954.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	1.80e-166	554.1	3	700

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/UCH

   S: 6    kewleLesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakqv 94
           k+wleLesdPglftllvedfgvk++ qvee+y+L++++    q+pv+g+++lFk++e+r+s+rk+++++++++v+d+di++++ffa+q+
   Q: 3    KGWLELESDPGLFTLLVEDFGVKGV-QVEEIYDLQSKC----QGPVYGFIFLFKWIEERRSRRKVSTLVDETSVIDDDIVNNMFFAHQL 86
           89***********************.************....*********************************************** PP
   S: 95   igNsCatyAllsvllncedklldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfvsy 183
           i+NsCat+Allsvllnc+++  dlG+tlsr+k++tk++spe+k++a+gn+++l+++hns+ar+e+r++pe+q++ ++++t+eafhfvsy
   Q: 87   IPNSCATHALLSVLLNCNNV--DLGPTLSRMKDFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGISAVRTMEAFHFVSY 173
           ******************99..******************************************************************* PP
   S: 184  vningrlyeldglkpfPldlgkkketeelkdklkvvraflerikllesde....irfnllaivadrrviktlrlnvlkid......... 259
           v+i+grl+eldglk++P+d+g++ ++ee++dk+++v+  +eri+l++++e    irfnl+a+v+drr++++ +l++lk++         
   Q: 174  VPIKGRLFELDGLKVYPIDHGPWADDEEWTDKARRVI--MERIGLATAGEpyhdIRFNLMAVVPDRRMKYESKLHILKMNrqtvlealq 260
           *************************************..************************************************** PP
   S: 260  ......................................................................................... 259
                                                                                                    
   Q: 261  qlirvtqpeliqsqksqesqspeeakpansktvapesthpdgadepasqghttatqspptkskpvakasassingvppanpnpivqrlp 349
           ***************************************************************************************** PP
   S: 260  ......................................................................................... 259
                                                                                                    
   Q: 350  afldnhnyakspmqeeedlaagvgrsrvpvrqhqqysddeddydddeeeevrntnsairykrkgqvkqehaagaadgqlsvlqpntinv 438
           ***************************************************************************************** PP
   S: 260  ......................................................................................... 259
                                                                                                    
   Q: 439  laeklkesqkdlsiplsikttgggaavaivthsqpsptpsnestdtaseigsafnsplrspirsanptrpsspvtshiskvlfgeedgl 527
           ***************************************************************************************** PP
   S: 260  .........................................................................keLlkLlkdieseeek 275
                                                                                    keLl+Llk++e+e+++
   Q: 528  lridclrynravrdlgpiissgllhltedgvfcplaaadggkssppsikpgeeaqvtikldekegseasgskeKELLALLKCVEAEIAN 616
           ***************************************************************************************** PP
   S: 276  ieaqlddekekrkkfkiddirRtenydeficifikdlaregilrklveetisevrefgvnegrlakqrkqgrekkirplkrkrk 359
           +ea+l++e+ekrkkfkidd+rRt+nydefic+fi++la+eg+l+ lve++is++r++gv++grl+kqrk++r+k++rp+k+kr+
   Q: 617  YEACLKEEVEKRKKFKIDDQRRTHNYDEFICTFISMLAQEGMLASLVEQNISVRRRQGVSIGRLHKQRKPDRRKRSRPYKAKRQ 700
           **********************************************************************************97 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MNKGWLELES DPGLFTLLVE DFGVKGVQVE EIYDLQSKCQ GPVYGFIFLF KWIEERRSRR 60
KVSTLVDETS VIDDDIVNNM FFAHQLIPNS CATHALLSVL LNCNNVDLGP TLSRMKDFTK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGCCGGTGG GGCCCAGAGT TGGGCGGGCG GCGGGGCCGG ACATGGCGGC GCGGGCCGGG 60
CCGCAGGAAG ATGAATAAGG GTTGGCTGGA GCTGGAGAGC GACCCCGGTG AGCCCCGGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005622--C:intracellular
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001263	Ailuropoda melanoleuca	80.87	0.00e+00	1068.00
IUUC-Apl-003405	Anas platyrhynchos	77.78	0.00e+00	706.00
IUUC-Aca-004836	Anolis carolinensis	81.43	0.00e+00	1151.00
IUUC-Ame-011946	Astyanax mexicanus	62.45	0.00e+00	876.00
IUUC-Bta-013131	Bos taurus	78.17	0.00e+00	915.00
IUUC-Cja-019599	Callithrix jacchus	83.01	0.00e+00	1125.00
IUUC-Cfa-021003	Canis familiaris	81.51	0.00e+00	1067.00
IUUC-Cpo-022143	Cavia porcellus	81.92	0.00e+00	1103.00
IUUC-Csa-023477	Chlorocebus sabaeus	83.01	0.00e+00	1115.00
IUUC-Cho-024734	Choloepus hoffmanni	66.28	2.00e-172	598.00
IUUC-Csv-025842	Ciona savignyi	62.03	1.00e-94	339.00
IUUC-Dre-027793	Danio rerio	66.14	0.00e+00	906.00
IUUC-Dno-029253	Dasypus novemcinctus	81.60	0.00e+00	1099.00
IUUC-Dor-030891	Dipodomys ordii	76.44	0.00e+00	1019.00
IUUC-Dme-031796	Drosophila melanogaster	62.31	2.00e-94	339.00
IUUC-Ete-032646	Echinops telfairi	73.58	1.00e-145	510.00
IUUC-Eca-033805	Equus caballus	82.53	0.00e+00	1091.00
IUUC-Eeu-035216	Erinaceus europaeus	77.21	1.00e-123	436.00
IUUC-Fca-035611	Felis catus	80.25	0.00e+00	1018.00
IUUC-Fal-037186	Ficedula albicollis	92.18	0.00e+00	1107.00
IUUC-Gmo-038824	Gadus morhua	70.34	1.00e-179	623.00
IUUC-Gac-042226	Gasterosteus aculeatus	69.12	0.00e+00	938.00
IUUC-Ggo-045122	Gorilla gorilla	82.33	0.00e+00	1125.00
IUUC-Hsa-045882	Homo sapiens	82.19	0.00e+00	1121.00
IUUC-Itr-048185	Ictidomys tridecemlineatus	82.47	0.00e+00	1105.00
IUUC-Lch-049960	Latimeria chalumnae	72.83	0.00e+00	976.00
IUUC-Loc-052408	Lepisosteus oculatus	77.66	0.00e+00	676.00
IUUC-Laf-054187	Loxodonta africana	82.19	0.00e+00	1109.00
IUUC-Mcc-055273	Macaca mulatta	81.64	0.00e+00	1097.00
IUUC-Meu-056267	Macropus eugenii	77.96	0.00e+00	1101.00
IUUC-Mga-059958	Meleagris gallopavo	99.34	7.00e-174	602.00
IUUC-Mmr-061280	Microcebus murinus	82.76	0.00e+00	1091.00
IUUC-Mdo-062625	Monodelphis domestica	83.13	0.00e+00	1174.00
IUUC-Mmu-063853	Mus musculus	81.10	0.00e+00	1097.00
IUUC-Mlu-067771	Myotis lucifugus	80.82	0.00e+00	1070.00
IUUC-Opr-070741	Ochotona princeps	82.33	0.00e+00	1111.00
IUUC-Ont-072172	Oreochromis niloticus	68.65	0.00e+00	950.00
IUUC-Oan-073167	Ornithorhynchus anatinus	78.07	0.00e+00	1089.00
IUUC-Ocu-074176	Oryctolagus cuniculus	81.59	0.00e+00	1066.00
IUUC-Ola-087203	Oryzias latipes	85.61	1.00e-135	475.00
IUUC-Oga-089153	Otolemur garnettii	82.36	0.00e+00	1092.00
IUUC-Oar-090008	Ovis aries	80.00	0.00e+00	1070.00
IUUC-Ptr-091234	Pan troglodytes	82.47	0.00e+00	1127.00
IUUC-Pan-092005	Papio anubis	82.74	0.00e+00	1125.00
IUUC-Psi-093995	Pelodiscus sinensis	87.70	0.00e+00	662.00
IUUC-Pma-094110	Petromyzon marinus	87.30	2.00e-64	239.00
IUUC-Pfo-097418	Poecilia formosa	67.88	0.00e+00	920.00
IUUC-Pab-098267	Pongo abelii	82.33	0.00e+00	1101.00
IUUC-Pca-101084	Procavia capensis	79.59	0.00e+00	1038.00
IUUC-Pva-102292	Pteropus vampyrus	84.88	0.00e+00	789.00
IUUC-Rno-105251	Rattus norvegicus	79.14	0.00e+00	1075.00
IUUC-Sha-107100	Sarcophilus harrisii	82.50	0.00e+00	1162.00
IUUC-Sar-113559	Sorex araneus	76.60	0.00e+00	939.00
IUUC-Ssc-115688	Sus scrofa	80.68	0.00e+00	1102.00
IUUC-Tgu-117424	Taeniopygia guttata	91.47	0.00e+00	1236.00
IUUC-Tru-118585	Takifugu rubripes	67.39	0.00e+00	928.00
IUUC-Tsy-119299	Tarsius syrichta	70.85	0.00e+00	815.00
IUUC-Tni-120808	Tetraodon nigroviridis	67.88	0.00e+00	934.00
IUUC-Tbe-127705	Tupaia belangeri	83.65	2.00e-158	551.00
IUUC-Ttr-128225	Tursiops truncatus	81.10	0.00e+00	1063.00
IUUC-Vpa-130193	Vicugna pacos	75.09	2.00e-105	376.00
IUUC-Xtr-132449	Xenopus tropicalis	73.10	0.00e+00	926.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence