iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Itr-048612

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01095423

Gene Name

KLHL40

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000003126.2	ENSSTOT00000003124.2	ENSSTOP00000002791.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.90e-15	56.9	34	97
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.80e-06	27.3	131	161

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           D+++  g++ef++h++vLaa+S++F+a fl e e     ++  ++dv+p+v+ ++l++lYt+++ ++
   Q: 34   DCVVRAGEREFPCHRLVLAACSPYFRARFLAEPETA---GELRLEDVSPDVVAQVLNYLYTSEIALD 97
           99999************************9998875...6999*******************99876 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhFk 32
            Ncl+++r++ l+dc +L+ aa+dfi++ F+
   Q: 131  ANCLAVFRLGLLLDCARLAVAARDFICSRFT 161
           6****************************96 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MTLGLEQAEE QRLYQQTLLQ DGLKDMLDHG KFLDCVVRAG EREFPCHRLV LAACSPYFRA 60
RFLAEPETAG ELRLEDVSPD VVAQVLNYLY TSEIALDEAS VQDLFAAAHR FQIPSIFTIC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGGCCCCCA CCATGACTCT GGGCTTGGAA CAAGCGGAGG AACAGCGGCT GTACCAGCAG 60
ACGCTCCTGC AGGATGGGCT CAAGGACATG CTGGACCACG GCAAGTTCCT GGACTGTGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030607--KLHL40
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031397--P:negative regulation of protein ubiquitination
GO:0048741--P:skeletal muscle fiber development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001792	Ailuropoda melanoleuca	89.42	0.00e+00	1077.00
IUUC-Apl-003748	Anas platyrhynchos	71.68	0.00e+00	912.00
IUUC-Aca-005275	Anolis carolinensis	64.76	0.00e+00	825.00
IUUC-Acl-008133	Aspergillus clavatus	33.87	4.00e-04	39.70
IUUC-Ame-011294	Astyanax mexicanus	56.87	0.00e+00	725.00
IUUC-Bta-012801	Bos taurus	93.27	0.00e+00	1153.00
IUUC-Cja-019795	Callithrix jacchus	91.48	0.00e+00	1028.00
IUUC-Cfa-021245	Canis familiaris	89.46	0.00e+00	800.00
IUUC-Cpo-022436	Cavia porcellus	89.89	0.00e+00	1150.00
IUUC-Csa-023105	Chlorocebus sabaeus	92.78	0.00e+00	1147.00
IUUC-Cin-025237	Ciona intestinalis	27.52	1.00e-60	227.00
IUUC-Dre-028603	Danio rerio	58.08	0.00e+00	756.00
IUUC-Dno-030015	Dasypus novemcinctus	76.72	0.00e+00	643.00
IUUC-Dor-030850	Dipodomys ordii	48.18	5.00e-121	427.00
IUUC-Dse-031465	Dothistroma septosporum	29.55	2.00e-05	43.10
IUUC-Ete-032697	Echinops telfairi	50.56	0.00e+00	646.00
IUUC-Eca-034393	Equus caballus	92.11	0.00e+00	1076.00
IUUC-Eeu-035245	Erinaceus europaeus	51.97	2.00e-179	621.00
IUUC-Fca-035823	Felis catus	82.81	0.00e+00	1006.00
IUUC-Fal-037632	Ficedula albicollis	72.64	0.00e+00	899.00
IUUC-Gmo-039697	Gadus morhua	57.26	0.00e+00	745.00
IUUC-Gga-040525	Gallus gallus	72.25	0.00e+00	916.00
IUUC-Gac-042421	Gasterosteus aculeatus	59.90	0.00e+00	769.00
IUUC-Ggo-045596	Gorilla gorilla	93.26	0.00e+00	1145.00
IUUC-Hsa-046235	Homo sapiens	93.10	0.00e+00	1143.00
IUUC-Lch-050123	Latimeria chalumnae	65.16	0.00e+00	875.00
IUUC-Loc-051824	Lepisosteus oculatus	62.76	0.00e+00	823.00
IUUC-Laf-053485	Loxodonta africana	88.57	0.00e+00	736.00
IUUC-Mcc-054909	Macaca mulatta	92.62	0.00e+00	1145.00
IUUC-Meu-055972	Macropus eugenii	75.92	0.00e+00	973.00
IUUC-Mga-059451	Meleagris gallopavo	72.89	0.00e+00	929.00
IUUC-Mmr-060736	Microcebus murinus	92.62	0.00e+00	1175.00
IUUC-Mdo-062563	Monodelphis domestica	76.89	0.00e+00	759.00
IUUC-Mmu-063549	Mus musculus	92.78	0.00e+00	1169.00
IUUC-Mpu-066262	Mustela putorius furo	94.07	0.00e+00	1164.00
IUUC-Mlu-067210	Myotis lucifugus	93.26	0.00e+00	1155.00
IUUC-Nle-069300	Nomascus leucogenys	92.05	0.00e+00	808.00
IUUC-Opr-070384	Ochotona princeps	86.54	0.00e+00	1045.00
IUUC-Ont-071273	Oreochromis niloticus	59.90	0.00e+00	758.00
IUUC-Oan-073476	Ornithorhynchus anatinus	51.52	0.00e+00	672.00
IUUC-Ocu-074499	Oryctolagus cuniculus	92.98	0.00e+00	1145.00
IUUC-Ola-087175	Oryzias latipes	59.08	0.00e+00	753.00
IUUC-Oga-088855	Otolemur garnettii	93.58	0.00e+00	1177.00
IUUC-Oar-089342	Ovis aries	80.61	0.00e+00	918.00
IUUC-Ptr-091028	Pan troglodytes	93.62	0.00e+00	792.00
IUUC-Pan-091827	Papio anubis	92.94	0.00e+00	1147.00
IUUC-Psi-092998	Pelodiscus sinensis	72.32	0.00e+00	924.00
IUUC-Pma-094586	Petromyzon marinus	58.19	1.00e-98	352.00
IUUC-Pfo-096216	Poecilia formosa	58.21	0.00e+00	766.00
IUUC-Pab-097656	Pongo abelii	93.32	0.00e+00	696.00
IUUC-Pca-100495	Procavia capensis	45.43	2.00e-163	568.00
IUUC-Pva-102331	Pteropus vampyrus	82.69	0.00e+00	1016.00
IUUC-Pte-104085	Pyrenophora teres	35.29	3.00e-05	42.40
IUUC-Pyt-104655	Pyrenophora triticirepentis	35.29	3.00e-05	42.70
IUUC-Rno-105613	Rattus norvegicus	91.62	0.00e+00	1037.00
IUUC-Sha-107091	Sarcophilus harrisii	77.55	0.00e+00	1008.00
IUUC-Sar-112941	Sorex araneus	88.91	0.00e+00	790.00
IUUC-Ssc-116276	Sus scrofa	93.91	0.00e+00	1161.00
IUUC-Tgu-116494	Taeniopygia guttata	72.48	0.00e+00	932.00
IUUC-Tru-118614	Takifugu rubripes	59.74	0.00e+00	778.00
IUUC-Tsy-119499	Tarsius syrichta	92.63	0.00e+00	663.00
IUUC-Tni-119776	Tetraodon nigroviridis	59.59	0.00e+00	769.00
IUUC-Tbe-127806	Tupaia belangeri	85.55	0.00e+00	1046.00
IUUC-Ttr-128813	Tursiops truncatus	91.33	0.00e+00	1153.00
IUUC-Vpa-130127	Vicugna pacos	93.78	0.00e+00	701.00
IUUC-Xtr-132942	Xenopus tropicalis	66.72	0.00e+00	870.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence