iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074499

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02056075

Gene Name

KLHL40

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000013151.3	ENSOCUT00000013146.3	ENSOCUP00000011317.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.80e-14	53.9	34	97
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	5.70e-06	25.7	131	161

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           D+++  g++ef++h++vLaa+S++F+a fl e e     ++  +++v+p+v+ ++l++lYt+++ ++
   Q: 34   DCVVRAGEREFPCHRLVLAACSPYFRARFLAEPERA---GELRLEEVSPDVVAQVLHYLYTSEIALD 97
           99999************************9988864...699999*****************99876 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhFk 32
            Ncl+++r++ l+dc +L+ aa+dfi+  F+
   Q: 131  ANCLAVFRLGLLLDCARLAVAARDFICARFT 161
           6***************************996 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MALGLEQAEE QRLYQQTLLQ DGLKDMLDHG KFLDCVVRAG EREFPCHRLV LAACSPYFRA 60
RFLAEPERAG ELRLEEVSPD VVAQVLHYLY TSEIALDEAS VQDLFAAAHR FQIPSIFTIC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGGGAGACA ACTGCGCAGT CTGAGCACGC CCCGGGGCAG GAGAGCAGCG CTCTTTTAGA 60
GAGGAGTGCC CCGGCCCGGT TGCGACCCCT TACGCCCCCC ACCATGGCGC TGGGCCTGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030607--KLHL40
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031397--P:negative regulation of protein ubiquitination
GO:0048741--P:skeletal muscle fiber development

KEGG

ocu:100350405

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001792	Ailuropoda melanoleuca	87.72	0.00e+00	1060.00
IUUC-Apl-003748	Anas platyrhynchos	71.22	0.00e+00	908.00
IUUC-Aca-005275	Anolis carolinensis	65.40	0.00e+00	822.00
IUUC-Acl-008133	Aspergillus clavatus	35.48	5.00e-05	42.70
IUUC-Ani-009446	Aspergillus nidulans	27.47	2.00e-04	39.70
IUUC-Ame-011294	Astyanax mexicanus	57.30	0.00e+00	727.00
IUUC-Bta-012801	Bos taurus	91.71	0.00e+00	1139.00
IUUC-Cja-019795	Callithrix jacchus	90.02	0.00e+00	1025.00
IUUC-Cfa-021245	Canis familiaris	91.72	0.00e+00	790.00
IUUC-Cpo-022436	Cavia porcellus	89.95	0.00e+00	1139.00
IUUC-Csa-023105	Chlorocebus sabaeus	91.87	0.00e+00	1135.00
IUUC-Cne-026865	Cryptococcus neoformans	28.57	2.10e+00	28.10
IUUC-Dre-028603	Danio rerio	58.19	0.00e+00	759.00
IUUC-Dno-030015	Dasypus novemcinctus	78.66	0.00e+00	636.00
IUUC-Dse-031465	Dothistroma septosporum	28.41	1.00e-04	40.80
IUUC-Eca-034393	Equus caballus	92.17	0.00e+00	1064.00
IUUC-Fca-035823	Felis catus	81.62	0.00e+00	984.00
IUUC-Fal-037632	Ficedula albicollis	71.54	0.00e+00	887.00
IUUC-Gmo-039697	Gadus morhua	58.48	0.00e+00	741.00
IUUC-Gga-040525	Gallus gallus	72.02	0.00e+00	911.00
IUUC-Gac-042421	Gasterosteus aculeatus	59.52	0.00e+00	768.00
IUUC-Ggo-045596	Gorilla gorilla	92.50	0.00e+00	1133.00
IUUC-Hsa-046235	Homo sapiens	92.66	0.00e+00	1133.00
IUUC-Itr-048612	Ictidomys tridecemlineatus	94.10	0.00e+00	1162.00
IUUC-Lch-050123	Latimeria chalumnae	64.90	0.00e+00	864.00
IUUC-Loc-051824	Lepisosteus oculatus	63.00	0.00e+00	810.00
IUUC-Laf-053485	Loxodonta africana	89.52	0.00e+00	720.00
IUUC-Mcc-054909	Macaca mulatta	91.55	0.00e+00	1133.00
IUUC-Meu-055972	Macropus eugenii	77.23	0.00e+00	974.00
IUUC-Mga-059451	Meleagris gallopavo	72.34	0.00e+00	915.00
IUUC-Mmr-060736	Microcebus murinus	91.87	0.00e+00	1151.00
IUUC-Mdo-062563	Monodelphis domestica	77.55	0.00e+00	754.00
IUUC-Mmu-063549	Mus musculus	92.03	0.00e+00	1157.00
IUUC-Mpu-066262	Mustela putorius furo	92.34	0.00e+00	1145.00
IUUC-Mlu-067210	Myotis lucifugus	91.87	0.00e+00	1137.00
IUUC-Nle-069300	Nomascus leucogenys	90.77	0.00e+00	788.00
IUUC-Opr-070384	Ochotona princeps	88.36	0.00e+00	1053.00
IUUC-Ont-071273	Oreochromis niloticus	60.16	0.00e+00	755.00
IUUC-Ola-087175	Oryzias latipes	59.27	0.00e+00	749.00
IUUC-Oga-088855	Otolemur garnettii	89.95	0.00e+00	1137.00
IUUC-Oar-089342	Ovis aries	78.95	0.00e+00	903.00
IUUC-Ptr-091028	Pan troglodytes	91.65	0.00e+00	784.00
IUUC-Pan-091827	Papio anubis	91.87	0.00e+00	1135.00
IUUC-Psi-092998	Pelodiscus sinensis	71.68	0.00e+00	915.00
IUUC-Pma-094586	Petromyzon marinus	65.40	6.00e-96	343.00
IUUC-Pfo-096216	Poecilia formosa	58.10	0.00e+00	762.00
IUUC-Pab-097656	Pongo abelii	90.33	0.00e+00	682.00
IUUC-Pva-102331	Pteropus vampyrus	83.57	0.00e+00	1006.00
IUUC-Pyt-104655	Pyrenophora triticirepentis	33.82	2.00e-04	40.00
IUUC-Rno-105613	Rattus norvegicus	90.62	0.00e+00	1023.00
IUUC-Sha-107091	Sarcophilus harrisii	78.90	0.00e+00	1009.00
IUUC-Sar-112941	Sorex araneus	88.27	0.00e+00	773.00
IUUC-Ssc-116276	Sus scrofa	92.66	0.00e+00	1150.00
IUUC-Tgu-116494	Taeniopygia guttata	71.14	0.00e+00	917.00
IUUC-Tru-118614	Takifugu rubripes	60.16	0.00e+00	770.00
IUUC-Tsy-119499	Tarsius syrichta	89.82	0.00e+00	651.00
IUUC-Tni-119776	Tetraodon nigroviridis	59.52	0.00e+00	765.00
IUUC-Tbe-127806	Tupaia belangeri	84.69	0.00e+00	1034.00
IUUC-Ttr-128813	Tursiops truncatus	91.55	0.00e+00	1139.00
IUUC-Vpa-130127	Vicugna pacos	92.56	0.00e+00	686.00
IUUC-Xtr-132942	Xenopus tropicalis	67.57	0.00e+00	862.00
IUUC-Xma-133573	Xiphophorus maculatus	58.07	0.00e+00	734.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence