iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000013169.3	ENSMMUT00000018477.3	ENSMMUP00000017302.3
ENSMMUG00000013169.3	ENSMMUT00000018479.3	ENSMMUP00000017304.3
ENSMMUG00000013169.3	ENSMMUT00000039712.2	ENSMMUP00000032778.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.70e-28	96.1	1473	1505
UBD/Beta-Prp	1.40e-73	248.8	1342	1646

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlr 31
           gH ++v+ + f ++  + ++++ Dg+++vW l 
   Q: 1473 GHRSKVNEVVFgPGeSHCATCGEDGSVRVWALA 1505
           8***********8889**************875 PP

UBD/Beta-Prp

   S: 14   tcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvw...dls..........tgkcv 87
           t++++    +ll  g  +g + vwd++ g ++ s + +++++  + +s++   lv+gs+ + +++w   ++s          +++ +
   Q: 1342 TSLCY-GAHPLLYCGTSSGQVCVWDTRAGRCFLSWEADDGGIGLLLCSSS--RLVSGSSTGRLRLWavgPVSelrckgsgarSSSVF 1425
           55566.667888999999********************************..7*************666444777988887666666 PP
   S: 88   htlk.ghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllr 173
           +  +   +  v+s sf+ s d  v+G++  t+    + +g+  + + sgh++ vn vv+ p ++ +++++ D+ vr+W l++++l+ 
   Q: 1426 MERElVLDGAVVSASFDGSVDMGVVGTRAGTLWFISWAEGTSTR-LISGHRSKVNEVVFGPGESHCATCGEDGSVRVWALASMELVI 1511
           66666789999*******99*************97778888888.88**************99************************ PP
   S: 174  tltgghtdsvyslsfdsng......kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsg 254
           +++   ++s  +l++++        ++l++g  dg++++++++++ +  +++ h    + v fs +++ ++sg +Dg + +  +r+g
   Q: 1512 QFQV-LNQSCLCLAWSPRCcgrpeqQRLAAGYGDGSLRIFSVSRTAMELKMHPHPVALTTVTFSTDGQTVLSGDKDGLVAVSHSRTG 1597
           **98.*********66655666666************************************************************** PP
   S: 255  dllktlqlhnssvisvav........lsfgdnvl.vlgsedskvniwkl 294
            + ++l+ h+   is  +        l++++  l +++s+d++v +w+ 
   Q: 1598 MTFRVLSDHQGAAISTICvtrkecedLGVEGTDLwLAASGDQRVSVWAS 1646
           **********666666663446666666666555455555*******85 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MARGSARRAR VPGSGVPGSR VGGRGAQGPR LGPEARVPAR AEYRLPGAHP RAPGAWLPSG 60
ARTRPARLAG VGVAGEGAES PGPTGSCLVP EAGPSSAVAP ARGAGPPDAR RPLPAAWQHP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCCGAG GTAGCGCGCG GCGGGCGCGG GTCCCGGGTT CCGGGGTTCC GGGGTCCAGG 60
GTCGGCGGCC GGGGCGCTCA GGGCCCCCGC CTAGGCCCCG AGGCCAGAGT CCCCGCTCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR007714--CFA20/WDR90/C3orf67
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR030466--WDR90

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF05018--DUF667
PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001801	Ailuropoda melanoleuca	66.76	0.00e+00	1301.00
IUUC-Apl-003387	Anas platyrhynchos	47.34	0.00e+00	924.00
IUUC-Aca-005235	Anolis carolinensis	47.54	0.00e+00	1400.00
IUUC-Ame-011595	Astyanax mexicanus	49.00	2.00e-179	624.00
IUUC-Bta-012328	Bos taurus	67.64	0.00e+00	1228.00
IUUC-Cja-019058	Callithrix jacchus	77.80	0.00e+00	2368.00
IUUC-Cfa-020934	Canis familiaris	62.47	0.00e+00	1140.00
IUUC-Cpo-022025	Cavia porcellus	58.42	0.00e+00	1818.00
IUUC-Cre-022928	Chlamydomonas reinhardtii	26.99	6.00e-49	190.00
IUUC-Csa-023022	Chlorocebus sabaeus	85.39	0.00e+00	2915.00
IUUC-Cin-025133	Ciona intestinalis	34.67	0.00e+00	640.00
IUUC-Csv-025816	Ciona savignyi	33.59	3.00e-154	540.00
IUUC-Dre-028823	Danio rerio	45.16	0.00e+00	870.00
IUUC-Dno-029211	Dasypus novemcinctus	73.29	0.00e+00	741.00
IUUC-Dor-030211	Dipodomys ordii	66.45	0.00e+00	1825.00
IUUC-Ete-032363	Echinops telfairi	53.40	0.00e+00	667.00
IUUC-Eca-034296	Equus caballus	60.66	0.00e+00	1825.00
IUUC-Eeu-035226	Erinaceus europaeus	49.30	0.00e+00	630.00
IUUC-Fca-035384	Felis catus	65.40	0.00e+00	1242.00
IUUC-Fal-037660	Ficedula albicollis	53.21	0.00e+00	897.00
IUUC-Gga-040666	Gallus gallus	54.18	0.00e+00	749.00
IUUC-Gac-041358	Gasterosteus aculeatus	44.27	0.00e+00	808.00
IUUC-Ggo-045121	Gorilla gorilla	85.77	0.00e+00	2824.00
IUUC-Hsa-046289	Homo sapiens	85.93	0.00e+00	2765.00
IUUC-Itr-048485	Ictidomys tridecemlineatus	67.01	0.00e+00	1196.00
IUUC-Lch-050009	Latimeria chalumnae	44.49	0.00e+00	831.00
IUUC-Loc-052629	Lepisosteus oculatus	47.83	0.00e+00	845.00
IUUC-Meu-056162	Macropus eugenii	60.66	0.00e+00	738.00
IUUC-Mga-060167	Meleagris gallopavo	46.21	0.00e+00	922.00
IUUC-Mmr-060761	Microcebus murinus	81.31	4.00e-145	507.00
IUUC-Mdo-061886	Monodelphis domestica	52.69	0.00e+00	1807.00
IUUC-Mmu-063652	Mus musculus	64.61	0.00e+00	1258.00
IUUC-Mlu-068141	Myotis lucifugus	61.18	0.00e+00	1937.00
IUUC-Nle-069133	Nomascus leucogenys	80.05	0.00e+00	1779.00
IUUC-Ont-072496	Oreochromis niloticus	44.42	0.00e+00	877.00
IUUC-Oan-072833	Ornithorhynchus anatinus	47.08	0.00e+00	803.00
IUUC-Ola-086564	Oryzias latipes	40.21	0.00e+00	1268.00
IUUC-Oga-088919	Otolemur garnettii	68.77	0.00e+00	2235.00
IUUC-Oar-089946	Ovis aries	52.92	0.00e+00	798.00
IUUC-Ptr-090755	Pan troglodytes	84.28	0.00e+00	2314.00
IUUC-Pan-092054	Papio anubis	87.80	0.00e+00	3056.00
IUUC-Psi-093467	Pelodiscus sinensis	52.99	0.00e+00	1014.00
IUUC-Pma-094553	Petromyzon marinus	43.19	0.00e+00	753.00
IUUC-Pfo-096849	Poecilia formosa	45.08	0.00e+00	795.00
IUUC-Pab-098320	Pongo abelii	84.60	0.00e+00	2461.00
IUUC-Pca-100172	Procavia capensis	60.96	0.00e+00	1811.00
IUUC-Pva-102772	Pteropus vampyrus	65.76	0.00e+00	1220.00
IUUC-Rno-105046	Rattus norvegicus	64.66	0.00e+00	1285.00
IUUC-Sha-107094	Sarcophilus harrisii	52.56	0.00e+00	1864.00
IUUC-Ssc-116257	Sus scrofa	63.80	0.00e+00	1157.00
IUUC-Tgu-117323	Taeniopygia guttata	59.08	0.00e+00	705.00
IUUC-Tru-118717	Takifugu rubripes	43.73	0.00e+00	816.00
IUUC-Tni-120108	Tetraodon nigroviridis	44.26	0.00e+00	811.00
IUUC-Ttr-128378	Tursiops truncatus	64.78	0.00e+00	1418.00
IUUC-Xtr-131760	Xenopus tropicalis	49.46	0.00e+00	963.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence