iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-012793

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

WD repeat-containing protein 6

Genbank Nucleotide ID

BC153250

Gene Name

WDR6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000018910.5	ENSBTAT00000025167.5	ENSBTAP00000025167.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.60e-20	72.5	207	240

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrt 32
           gH + ++++++  s +ll+++s D ++++W + +
   Q: 207  GHVGVIFSMSYleSKGLLATASEDRSVRIWKVGD 240
           8*********99766***************9865 PP

Organism

Bos taurus

Functional Description
(View)

Enhances the STK11/LKB1-induced cell growth suppression activity. Negative regulator of amino acid starvation-induced autophagy.

Protein Sequence
(Fasta)

MDAHEDYVWP RATSELILLP VTGLECVGER LLAGEGPDVL VYTLDFGGHL RMMKRVQNLL 60
GHYLIHGFRV RPEPNGDLDS EVMVAAFGSK GLRIVKISWG QGRFRELWRS GLWNMSDWIW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCCATGGAC GCTCACGAGG ACTACGTTTG GCCGCGGGCA ACCTCGGAGC TCATACTCCT 60
CCCGGTCACG GGTCTGGAGT GCGTGGGGGA GCGGCTATTG GCGGGTGAGT TGTGGTTCGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0007--Acetylation
KW-0131--Cell cycle
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005886--C:plasma membrane
GO:0007049--P:cell cycle

KEGG

bta:526884

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000976	Aegilops tauschii	21.36	5.00e-20	94.00
IUUC-Aml-001786	Ailuropoda melanoleuca	92.10	0.00e+00	2049.00
IUUC-Atr-003053	Amborella trichopoda	22.32	1.00e-31	132.00
IUUC-Apl-003178	Anas platyrhynchos	47.13	2.00e-134	472.00
IUUC-Aca-004886	Anolis carolinensis	43.97	0.00e+00	843.00
IUUC-Aly-005509	Arabidopsis lyrata	27.78	9.00e-29	122.00
IUUC-Ath-007109	Arabidopsis thaliana	26.11	7.00e-26	113.00
IUUC-Ago-007817	Ashbya gossypii	22.51	5.00e-40	159.00
IUUC-Acl-008020	Aspergillus clavatus	21.36	2.00e-25	111.00
IUUC-Afl-008608	Aspergillus flavus	21.26	4.00e-14	73.60
IUUC-Afu-009035	Aspergillus fumigatus	22.23	3.00e-30	127.00
IUUC-Ani-009359	Aspergillus nidulans	24.24	9.00e-25	109.00
IUUC-Ang-009692	Aspergillus niger	21.29	3.00e-17	84.70
IUUC-Aor-010056	Aspergillus oryzae	21.20	2.00e-24	108.00
IUUC-Ate-010299	Aspergillus terreus	22.26	6.00e-29	123.00
IUUC-Ame-011051	Astyanax mexicanus	33.64	3.00e-149	523.00
IUUC-Bgr-012077	Blumeria graminis	20.40	7.00e-13	70.10
IUUC-Bci-013679	Botrytis cinerea	21.52	1.00e-08	55.80
IUUC-Bdi-014401	Brachypodium distachyon	23.31	1.00e-32	136.00
IUUC-Bol-015628	Brassica oleracea	23.50	1.00e-30	129.00
IUUC-Bra-017446	Brassica rapa	23.47	4.00e-32	134.00
IUUC-Cja-018910	Callithrix jacchus	88.46	0.00e+00	1966.00
IUUC-Cfa-021260	Canis familiaris	92.01	0.00e+00	2055.00
IUUC-Cpo-022205	Cavia porcellus	85.59	0.00e+00	1942.00
IUUC-Csa-023510	Chlorocebus sabaeus	88.02	0.00e+00	1935.00
IUUC-Cgl-026380	Colletotrichum gloeosporioides	27.01	5.00e-09	56.60
IUUC-Dre-028004	Danio rerio	34.11	1.00e-154	541.00
IUUC-Dno-029804	Dasypus novemcinctus	84.83	0.00e+00	1848.00
IUUC-Dor-030512	Dipodomys ordii	82.29	0.00e+00	1455.00
IUUC-Dme-032047	Drosophila melanogaster	22.20	2.00e-26	114.00
IUUC-Ete-033076	Echinops telfairi	81.73	0.00e+00	692.00
IUUC-Eca-033727	Equus caballus	91.12	0.00e+00	1634.00
IUUC-Eeu-035210	Erinaceus europaeus	84.52	0.00e+00	1916.00
IUUC-Fca-035433	Felis catus	92.17	0.00e+00	2078.00
IUUC-Fal-036807	Ficedula albicollis	46.04	1.00e-160	559.00
IUUC-Fox-037749	Fusarium oxysporum	22.22	7.00e-13	69.70
IUUC-Fso-038164	Fusarium solani	21.76	3.00e-17	84.30
IUUC-Gmo-039180	Gadus morhua	35.00	6.00e-141	495.00
IUUC-Gga-040482	Gallus gallus	43.57	4.00e-172	598.00
IUUC-Gac-042066	Gasterosteus aculeatus	35.35	2.00e-148	520.00
IUUC-Gma-042704	Glycine max	22.06	4.00e-27	117.00
IUUC-Ggo-044942	Gorilla gorilla	89.26	0.00e+00	1962.00
IUUC-Hsa-046408	Homo sapiens	89.44	0.00e+00	1993.00
IUUC-Hvu-047448	Hordeum vulgare	21.60	4.00e-25	110.00
IUUC-Itr-048756	Ictidomys tridecemlineatus	89.51	0.00e+00	2022.00
IUUC-Kpa-049257	Komagataella pastoris	21.87	4.00e-37	150.00
IUUC-Lch-050170	Latimeria chalumnae	42.03	0.00e+00	862.00
IUUC-Lpe-051575	Leersia perrieri	21.49	9.00e-28	119.00
IUUC-Loc-052341	Lepisosteus oculatus	35.30	7.00e-141	494.00
IUUC-Lma-053318	Leptosphaeria maculans	23.75	2.00e-12	68.90
IUUC-Laf-054299	Loxodonta africana	86.04	0.00e+00	1887.00
IUUC-Mcc-055438	Macaca mulatta	88.82	0.00e+00	1943.00
IUUC-Meu-056206	Macropus eugenii	47.31	0.00e+00	664.00
IUUC-Mor-056928	Magnaporthe oryzae	22.68	1.00e-13	72.40
IUUC-Mtr-058455	Medicago truncatula	23.54	3.00e-29	124.00
IUUC-Mga-059962	Meleagris gallopavo	45.02	3.00e-146	511.00
IUUC-Mvi-060438	Microbotryum violaceum	25.65	2.00e-15	78.60
IUUC-Mmr-061353	Microcebus murinus	90.93	0.00e+00	2018.00
IUUC-Mdo-062061	Monodelphis domestica	49.79	0.00e+00	896.00
IUUC-Mmu-064386	Mus musculus	84.64	0.00e+00	1910.00
IUUC-Mac-065653	Musa acuminata	22.92	1.00e-43	172.00
IUUC-Mpu-066420	Mustela putorius furo	91.65	0.00e+00	2073.00
IUUC-Mlu-068104	Myotis lucifugus	87.57	0.00e+00	1971.00
IUUC-Nfi-068301	Neosartorya fischeri	22.87	1.00e-16	82.40
IUUC-Ncr-068718	Neurospora crassa	21.71	1.00e-14	76.30
IUUC-Nle-069836	Nomascus leucogenys	79.27	0.00e+00	1478.00
IUUC-Ont-071605	Oreochromis niloticus	34.94	2.00e-159	556.00
IUUC-Oan-073645	Ornithorhynchus anatinus	47.85	0.00e+00	979.00
IUUC-Ocu-074708	Oryctolagus cuniculus	87.11	0.00e+00	1897.00
IUUC-Oba-075290	Oryza barthii	21.71	1.00e-26	115.00
IUUC-Obr-076647	Oryza brachyantha	22.67	2.00e-31	131.00
IUUC-Ogl-077628	Oryza glaberrima	22.37	2.00e-32	135.00
IUUC-Ogu-078209	Oryza glumaepatula	22.01	2.00e-22	101.00
IUUC-Oin-079342	Oryza indica	22.44	1.00e-32	135.00
IUUC-Olo-080334	Oryza longistaminata	21.24	4.00e-26	115.00
IUUC-Ome-081776	Oryza meridionalis	25.32	8.00e-21	96.70
IUUC-Oni-082311	Oryza nivara	22.44	2.00e-32	135.00
IUUC-Opu-083195	Oryza punctata	21.84	1.00e-30	129.00
IUUC-Oru-085006	Oryza rufipogon	21.58	6.00e-26	113.00
IUUC-Osa-085317	Oryza sativa	22.24	9.00e-32	132.00
IUUC-Ola-087145	Oryzias latipes	34.80	2.00e-142	500.00
IUUC-Olu-087785	Ostreococcus lucimarinus	26.47	3.00e-11	64.30
IUUC-Oga-088206	Otolemur garnettii	89.26	0.00e+00	2052.00
IUUC-Oar-089802	Ovis aries	97.14	0.00e+00	2115.00
IUUC-Ptr-091528	Pan troglodytes	80.92	0.00e+00	1753.00
IUUC-Pan-092782	Papio anubis	88.46	0.00e+00	1953.00
IUUC-Psi-093102	Pelodiscus sinensis	48.40	2.00e-135	476.00
IUUC-Ppa-095436	Physcomitrella patens	22.67	7.00e-35	143.00
IUUC-Pfo-097423	Poecilia formosa	33.69	4.00e-143	502.00
IUUC-Pab-097763	Pongo abelii	89.17	0.00e+00	1956.00
IUUC-Pop-099090	Populus trichocarpa	26.25	1.00e-23	106.00
IUUC-Pca-100173	Procavia capensis	84.44	0.00e+00	1867.00
IUUC-Ppe-101580	Prunus persica	24.10	4.00e-31	130.00
IUUC-Pva-102715	Pteropus vampyrus	91.65	0.00e+00	2008.00
IUUC-Pgr-103424	Puccinia graminis	21.61	2.00e-19	91.30
IUUC-Pte-104316	Pyrenophora teres	23.36	4.00e-10	60.80
IUUC-Pyt-104676	Pyrenophora triticirepentis	22.80	4.00e-09	57.40
IUUC-Rno-105122	Rattus norvegicus	86.47	0.00e+00	1970.00
IUUC-Sce-106465	Saccharomyces cerevisiae	20.59	2.00e-25	111.00
IUUC-Sha-107208	Sarcophilus harrisii	48.74	0.00e+00	1019.00
IUUC-Sja-107771	Schizosaccharomyces japonicus	25.75	5.00e-19	90.10
IUUC-Spo-108272	Schizosaccharomyces pombe	20.60	7.00e-35	142.00
IUUC-Smo-108961	Selaginella moellendorffii	23.64	2.00e-40	162.00
IUUC-Sit-109932	Setaria italica	22.02	1.00e-31	132.00
IUUC-Sly-111685	Solanum lycopersicum	24.13	2.00e-35	144.00
IUUC-Sar-112998	Sorex araneus	86.69	0.00e+00	1991.00
IUUC-Sbi-114074	Sorghum bicolor	22.62	8.00e-35	142.00
IUUC-Ssc-115619	Sus scrofa	91.23	0.00e+00	981.00
IUUC-Tgu-117485	Taeniopygia guttata	46.07	9.00e-154	536.00
IUUC-Tru-118104	Takifugu rubripes	35.87	1.00e-158	554.00
IUUC-Tni-119995	Tetraodon nigroviridis	35.95	5.00e-150	525.00
IUUC-Tca-121790	Theobroma cacao	24.24	2.00e-31	131.00
IUUC-Tre-122080	Trichoderma reesei	21.38	1.00e-17	86.30
IUUC-Tvi-122306	Trichoderma virens	27.89	2.00e-08	55.10
IUUC-Tae-125371	Triticum aestivum	22.31	5.00e-34	140.00
IUUC-Tur-126787	Triticum urartu	22.38	3.00e-30	127.00
IUUC-Tme-126957	Tuber melanosporum	24.83	9.00e-08	52.80
IUUC-Tbe-128082	Tupaia belangeri	89.93	2.00e-152	533.00
IUUC-Ttr-128387	Tursiops truncatus	95.74	0.00e+00	1012.00
IUUC-Vda-129804	Verticillium dahliae	21.46	7.00e-09	56.60
IUUC-Vpa-130257	Vicugna pacos	90.82	2.00e-169	588.00
IUUC-Vvi-131701	Vitis vinifera	29.27	2.00e-27	119.00
IUUC-Xtr-132622	Xenopus tropicalis	41.81	0.00e+00	867.00
IUUC-Xma-134014	Xiphophorus maculatus	35.10	4.00e-154	538.00
IUUC-Yli-134589	Yarrowia lipolytica	21.48	2.00e-21	97.80
IUUC-Zma-135732	Zea mays	21.88	5.00e-38	153.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence