iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003294

Ensembl Protein ID

ENSAPLP00000013983.1

UniProt Accession

U3J3A6; U3J3A6_ANAPL

Genbank Protein ID

ENSAPLP00000013983

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01111254

Gene Name

SCAP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000014099.1	ENSAPLT00000014751.1	ENSAPLP00000013983.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.90e-18	64.6	1109	1145

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsd.tl.lvsGsdDgtikvWDlrtgvll 36
           gH++ +t++   d t+ l+sG+ Dg i +WD+ tg ++
   Q: 1109 GHSGAITAVYM-DqTMvLASGGQDGAICLWDVLTGSKV 1145
           8********88.446648**************999765 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

MTLTEKLRER ISRAFYSHGL LCASYPIPII LFTGLCILAC CYPLLKLPLP GTGPVEYSTP 60
VKDYFPPSPD PVSQQGDLGE RPDWYVGAPV AYIQQIFVKA TVSPWQKNFL AVDVFRSPLS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACCCTGA CTGAAAAGCT GCGCGAGAGG ATATCGCGGG CCTTCTACAG CCACGGGCTG 60
CTCTGCGCCT CCTACCCCAT CCCCATCATC CTCTTCACGG GGCTCTGTAT TTTGGCCTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0853--WD repeat

Interpro

IPR030225--SCAP
IPR000731--SSD
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50156--SSD
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12349--Sterol-sensing
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0015485--F:cholesterol binding
GO:0008203--P:cholesterol metabolic process
GO:0045540--P:regulation of cholesterol biosynthetic process
GO:0042304--P:regulation of fatty acid biosynthetic process
GO:0001666--P:response to hypoxia
GO:0032868--P:response to insulin
GO:0032933--P:SREBP signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001802	Ailuropoda melanoleuca	83.90	0.00e+00	976.00
IUUC-Aca-004424	Anolis carolinensis	76.50	0.00e+00	1726.00
IUUC-Bta-013478	Bos taurus	76.70	0.00e+00	1742.00
IUUC-Cel-018160	Caenorhabditis elegans	26.25	7.00e-76	278.00
IUUC-Cja-019123	Callithrix jacchus	74.42	0.00e+00	1682.00
IUUC-Cfa-021082	Canis familiaris	76.32	0.00e+00	1707.00
IUUC-Cpo-022477	Cavia porcellus	74.34	0.00e+00	1653.00
IUUC-Csa-023176	Chlorocebus sabaeus	74.71	0.00e+00	1679.00
IUUC-Cin-025490	Ciona intestinalis	38.10	1.00e-94	340.00
IUUC-Csv-026115	Ciona savignyi	38.07	4.00e-139	489.00
IUUC-Dre-028008	Danio rerio	69.49	0.00e+00	1617.00
IUUC-Dno-028887	Dasypus novemcinctus	79.78	0.00e+00	1063.00
IUUC-Dor-030467	Dipodomys ordii	85.99	0.00e+00	815.00
IUUC-Dme-032087	Drosophila melanogaster	32.77	2.00e-113	403.00
IUUC-Ete-032372	Echinops telfairi	64.41	0.00e+00	977.00
IUUC-Eca-033896	Equus caballus	76.93	0.00e+00	1806.00
IUUC-Eeu-035099	Erinaceus europaeus	73.33	0.00e+00	1023.00
IUUC-Fca-035616	Felis catus	73.79	0.00e+00	1662.00
IUUC-Fal-037231	Ficedula albicollis	85.79	0.00e+00	2024.00
IUUC-Gmo-039439	Gadus morhua	74.42	0.00e+00	692.00
IUUC-Gac-041516	Gasterosteus aculeatus	68.26	0.00e+00	1574.00
IUUC-Hsa-046674	Homo sapiens	76.50	0.00e+00	1762.00
IUUC-Itr-048879	Ictidomys tridecemlineatus	76.79	0.00e+00	1767.00
IUUC-Lch-049689	Latimeria chalumnae	75.39	0.00e+00	1816.00
IUUC-Loc-052417	Lepisosteus oculatus	55.37	3.00e-156	545.00
IUUC-Laf-053795	Loxodonta africana	75.44	0.00e+00	1754.00
IUUC-Mcc-055502	Macaca mulatta	76.58	0.00e+00	1761.00
IUUC-Mga-059805	Meleagris gallopavo	94.59	0.00e+00	2209.00
IUUC-Mmr-060997	Microcebus murinus	76.50	0.00e+00	1794.00
IUUC-Mdo-062940	Monodelphis domestica	80.46	0.00e+00	1787.00
IUUC-Mmu-063255	Mus musculus	76.66	0.00e+00	1754.00
IUUC-Mpu-066158	Mustela putorius furo	76.90	0.00e+00	1768.00
IUUC-Mlu-067201	Myotis lucifugus	73.71	0.00e+00	1697.00
IUUC-Nle-069145	Nomascus leucogenys	59.53	0.00e+00	1145.00
IUUC-Opr-070797	Ochotona princeps	72.16	0.00e+00	1611.00
IUUC-Ont-071553	Oreochromis niloticus	68.25	0.00e+00	1598.00
IUUC-Ocu-074598	Oryctolagus cuniculus	76.54	0.00e+00	1738.00
IUUC-Ola-086650	Oryzias latipes	83.18	2.00e-110	390.00
IUUC-Oar-089287	Ovis aries	73.86	0.00e+00	947.00
IUUC-Pan-092004	Papio anubis	76.65	0.00e+00	1742.00
IUUC-Psi-093028	Pelodiscus sinensis	83.58	0.00e+00	1855.00
IUUC-Pma-094145	Petromyzon marinus	50.95	0.00e+00	1156.00
IUUC-Pfo-096320	Poecilia formosa	68.58	0.00e+00	1607.00
IUUC-Pab-097862	Pongo abelii	76.55	0.00e+00	1765.00
IUUC-Pca-100862	Procavia capensis	66.12	0.00e+00	1372.00
IUUC-Pva-103050	Pteropus vampyrus	76.20	0.00e+00	1129.00
IUUC-Rno-105852	Rattus norvegicus	76.92	0.00e+00	1765.00
IUUC-Sha-107312	Sarcophilus harrisii	78.97	0.00e+00	1806.00
IUUC-Sar-113311	Sorex araneus	69.17	0.00e+00	655.00
IUUC-Ssc-116356	Sus scrofa	76.78	0.00e+00	1791.00
IUUC-Tgu-116896	Taeniopygia guttata	74.45	0.00e+00	795.00
IUUC-Tru-118197	Takifugu rubripes	68.22	0.00e+00	1597.00
IUUC-Tni-119823	Tetraodon nigroviridis	65.98	0.00e+00	1563.00
IUUC-Ttr-129164	Tursiops truncatus	76.38	0.00e+00	1739.00
IUUC-Xtr-132819	Xenopus tropicalis	73.40	0.00e+00	1776.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence