iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000020354.3	ENSXETT00000043908.3	ENSXETP00000043908.3
ENSXETG00000020354.3	ENSXETT00000061992.1	ENSXETP00000061599.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-16	59.9	1157	1190

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsdtl.lvsGsdDgtikvWDlrtg 33
           gH++++t++  ++t+ l+sG+ Dg i +WD+ tg
   Q: 1157 GHSGGITAIYIDETMvLASGGQDGAICLWDVLTG 1190
           8********88546658*************9887 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MPLTDKLRER ISRAFYSHGL LCASYPIPII ILTALCILAS CYPLLKLPLP GTGPVEYVTP 60
VRDYSPPPLE PSPEDHSDRP DWYVGLPVSY IQQVLVKAVV SPWDKDFLAV DVFRSPLSRV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCCCTGA CTGATAAGCT GCGTGAGAGG ATATCGCGGG CCTTCTACAG CCATGGGCTG 60
CTCTGTGCCT CCTACCCTAT CCCCATCATC ATCCTCACTG CCCTCTGCAT TCTGGCCTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0677--Repeat
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0853--WD repeat

Interpro

IPR002469--Peptidase_S9B_N
IPR030225--SCAP
IPR000731--SSD
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50156--SSD
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12349--Sterol-sensing
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0015485--F:cholesterol binding
GO:0008203--P:cholesterol metabolic process
GO:0019915--P:lipid storage
GO:0032933--P:SREBP signaling pathway

KEGG

xtr:100145201

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001802	Ailuropoda melanoleuca	73.81	0.00e+00	851.00
IUUC-Apl-003294	Anas platyrhynchos	73.32	0.00e+00	1729.00
IUUC-Aca-004424	Anolis carolinensis	64.81	0.00e+00	1478.00
IUUC-Bta-013478	Bos taurus	68.37	0.00e+00	1572.00
IUUC-Cel-018160	Caenorhabditis elegans	29.64	4.00e-67	249.00
IUUC-Cja-019123	Callithrix jacchus	66.94	0.00e+00	1496.00
IUUC-Cfa-021082	Canis familiaris	67.59	0.00e+00	1502.00
IUUC-Cpo-022477	Cavia porcellus	66.87	0.00e+00	1501.00
IUUC-Csa-023176	Chlorocebus sabaeus	80.18	0.00e+00	787.00
IUUC-Cin-025490	Ciona intestinalis	34.78	1.00e-81	297.00
IUUC-Csv-026115	Ciona savignyi	35.85	9.00e-129	454.00
IUUC-Dre-028008	Danio rerio	63.93	0.00e+00	1514.00
IUUC-Dno-028887	Dasypus novemcinctus	69.49	0.00e+00	909.00
IUUC-Dor-030467	Dipodomys ordii	77.93	0.00e+00	720.00
IUUC-Dme-032087	Drosophila melanogaster	32.97	5.00e-114	405.00
IUUC-Ete-032372	Echinops telfairi	57.65	0.00e+00	899.00
IUUC-Eca-033896	Equus caballus	69.11	0.00e+00	1626.00
IUUC-Eeu-035099	Erinaceus europaeus	65.16	0.00e+00	891.00
IUUC-Fca-035616	Felis catus	71.61	0.00e+00	858.00
IUUC-Fal-037231	Ficedula albicollis	71.38	0.00e+00	1640.00
IUUC-Gmo-039439	Gadus morhua	72.97	0.00e+00	654.00
IUUC-Gac-041516	Gasterosteus aculeatus	65.07	0.00e+00	1513.00
IUUC-Hsa-046674	Homo sapiens	68.52	0.00e+00	1588.00
IUUC-Itr-048879	Ictidomys tridecemlineatus	68.24	0.00e+00	1568.00
IUUC-Lch-049689	Latimeria chalumnae	69.57	0.00e+00	1682.00
IUUC-Loc-052417	Lepisosteus oculatus	49.61	1.00e-149	523.00
IUUC-Laf-053795	Loxodonta africana	68.45	0.00e+00	1065.00
IUUC-Mcc-055502	Macaca mulatta	68.34	0.00e+00	1583.00
IUUC-Mga-059805	Meleagris gallopavo	73.78	0.00e+00	1728.00
IUUC-Mmr-060997	Microcebus murinus	68.42	0.00e+00	1618.00
IUUC-Mdo-062940	Monodelphis domestica	70.39	0.00e+00	1607.00
IUUC-Mmu-063255	Mus musculus	68.52	0.00e+00	1583.00
IUUC-Mpu-066158	Mustela putorius furo	68.48	0.00e+00	1587.00
IUUC-Mlu-067201	Myotis lucifugus	67.09	0.00e+00	1546.00
IUUC-Nle-069145	Nomascus leucogenys	70.72	0.00e+00	992.00
IUUC-Opr-070797	Ochotona princeps	64.77	0.00e+00	1468.00
IUUC-Ont-071553	Oreochromis niloticus	64.49	0.00e+00	1520.00
IUUC-Ocu-074598	Oryctolagus cuniculus	68.19	0.00e+00	1569.00
IUUC-Ola-086650	Oryzias latipes	83.33	7.00e-112	395.00
IUUC-Oar-089287	Ovis aries	65.82	0.00e+00	847.00
IUUC-Pan-092004	Papio anubis	68.41	0.00e+00	1563.00
IUUC-Psi-093028	Pelodiscus sinensis	70.51	0.00e+00	1511.00
IUUC-Pma-094145	Petromyzon marinus	49.28	0.00e+00	1114.00
IUUC-Pfo-096320	Poecilia formosa	64.65	0.00e+00	1526.00
IUUC-Pab-097862	Pongo abelii	68.44	0.00e+00	1586.00
IUUC-Pca-100862	Procavia capensis	59.00	0.00e+00	1223.00
IUUC-Pva-103050	Pteropus vampyrus	70.60	0.00e+00	1011.00
IUUC-Rno-105852	Rattus norvegicus	68.52	0.00e+00	1584.00
IUUC-Sha-107312	Sarcophilus harrisii	69.22	0.00e+00	1587.00
IUUC-Sar-113311	Sorex araneus	64.96	0.00e+00	642.00
IUUC-Ssc-116356	Sus scrofa	68.41	0.00e+00	1618.00
IUUC-Tgu-116896	Taeniopygia guttata	61.18	2.00e-107	383.00
IUUC-Tru-118197	Takifugu rubripes	64.29	0.00e+00	1512.00
IUUC-Tni-119823	Tetraodon nigroviridis	61.81	0.00e+00	1491.00
IUUC-Ttr-129164	Tursiops truncatus	68.74	0.00e+00	1597.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence