iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-072160

Ensembl Protein ID

ENSONIP00000022764.1

UniProt Accession

I3KNR9; I3KNR9_ORENI

Genbank Protein ID

ENSONIP00000022764

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AERX01018844

Gene Name

keap1b; keap1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000018066.1	ENSONIT00000022784.1	ENSONIP00000022764.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	4.30e-12	46.6	48	120
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	6.20e-10	38.2	154	184

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvv.....ggeeffahkivLaasSsvFyalflmeleesksklmveikd..vqpevfrallkFlYtgklde 67
           +Dv+l v     + + f ahk+vLa+sS+vF+a+f+++l+e    + v i++     +v+  l++F Yt +++ 
   Q: 48   CDVTLRVrykdlEAVDFVAHKVVLASSSPVFRAMFTNGLKECG-MELVPIEGihPRVQVMDRLIEFAYTASISV 120
           89999997776569****************************9.999****84455679**********98875 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           ++N++gi +fA++ +c++L+++a+++i  +F
   Q: 154  PSNAIGIASFAEQIGCTELHQKAREYIYMNF 184
           89****************************9 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MTECLTEYKA LVTPSTRNGH RVFSYTLESH TSAAFAIMNE LRLERQLCDV TLRVRYKDLE 60
AVDFVAHKVV LASSSPVFRA MFTNGLKECG MELVPIEGIH PRVQVMDRLI EFAYTASISV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGCTGTCAG CTGAACCAAC TGCTTCTTGG TAAATAAACA AACAAATAGG TGGGCATCCT 60
CAAGGAAGGC TTCTCCAGAG AAAACAACGA AACACCGCTA CCACTTCATT CCTAAAGGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR030563--KEAP1
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0071379--P:cellular response to prostaglandin stimulus
GO:0071466--P:cellular response to xenobiotic stimulus
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001377	Ailuropoda melanoleuca	77.98	0.00e+00	957.00
IUUC-Aca-005389	Anolis carolinensis	77.13	0.00e+00	948.00
IUUC-Ame-010749	Astyanax mexicanus	89.66	0.00e+00	1097.00
IUUC-Bta-013505	Bos taurus	77.31	0.00e+00	947.00
IUUC-Cja-018823	Callithrix jacchus	76.97	0.00e+00	943.00
IUUC-Cfa-021202	Canis familiaris	77.65	0.00e+00	953.00
IUUC-Cpo-021830	Cavia porcellus	76.51	0.00e+00	659.00
IUUC-Csa-023728	Chlorocebus sabaeus	77.14	0.00e+00	944.00
IUUC-Cin-025195	Ciona intestinalis	53.68	0.00e+00	631.00
IUUC-Csv-026155	Ciona savignyi	51.99	7.00e-171	593.00
IUUC-Dre-027388	Danio rerio	85.57	0.00e+00	1054.00
IUUC-Dno-029066	Dasypus novemcinctus	69.36	0.00e+00	819.00
IUUC-Dor-030674	Dipodomys ordii	77.43	0.00e+00	667.00
IUUC-Dme-032165	Drosophila melanogaster	50.44	2.00e-156	546.00
IUUC-Eca-034381	Equus caballus	75.46	0.00e+00	926.00
IUUC-Eeu-034791	Erinaceus europaeus	78.40	0.00e+00	660.00
IUUC-Fca-036067	Felis catus	77.82	0.00e+00	955.00
IUUC-Gmo-039691	Gadus morhua	88.20	0.00e+00	1100.00
IUUC-Gga-040266	Gallus gallus	74.20	0.00e+00	894.00
IUUC-Gac-041866	Gasterosteus aculeatus	92.31	0.00e+00	1143.00
IUUC-Ggo-044719	Gorilla gorilla	77.31	0.00e+00	947.00
IUUC-Hsa-046255	Homo sapiens	77.31	0.00e+00	947.00
IUUC-Itr-048457	Ictidomys tridecemlineatus	77.65	0.00e+00	955.00
IUUC-Lch-049646	Latimeria chalumnae	80.30	0.00e+00	977.00
IUUC-Loc-052022	Lepisosteus oculatus	59.47	0.00e+00	645.00
IUUC-Laf-054579	Loxodonta africana	77.14	0.00e+00	949.00
IUUC-Mcc-055315	Macaca mulatta	77.14	0.00e+00	944.00
IUUC-Meu-056288	Macropus eugenii	73.20	0.00e+00	882.00
IUUC-Mmr-061639	Microcebus murinus	76.97	0.00e+00	950.00
IUUC-Mdo-062072	Monodelphis domestica	78.66	0.00e+00	966.00
IUUC-Mmu-063622	Mus musculus	76.64	0.00e+00	944.00
IUUC-Mpu-066737	Mustela putorius furo	75.74	0.00e+00	932.00
IUUC-Mlu-068173	Myotis lucifugus	77.48	0.00e+00	950.00
IUUC-Nle-069336	Nomascus leucogenys	45.41	3.00e-122	432.00
IUUC-Opr-070432	Ochotona princeps	77.65	0.00e+00	949.00
IUUC-Oan-072691	Ornithorhynchus anatinus	71.21	0.00e+00	839.00
IUUC-Ocu-073798	Oryctolagus cuniculus	77.14	0.00e+00	946.00
IUUC-Ola-086367	Oryzias latipes	86.86	0.00e+00	1075.00
IUUC-Oga-088231	Otolemur garnettii	77.31	0.00e+00	949.00
IUUC-Oar-089227	Ovis aries	76.13	0.00e+00	925.00
IUUC-Ptr-091460	Pan troglodytes	77.31	0.00e+00	947.00
IUUC-Pan-092713	Papio anubis	77.14	0.00e+00	944.00
IUUC-Pfo-096468	Poecilia formosa	93.86	0.00e+00	1140.00
IUUC-Pab-098357	Pongo abelii	77.31	0.00e+00	947.00
IUUC-Pca-100837	Procavia capensis	76.97	0.00e+00	939.00
IUUC-Pva-103249	Pteropus vampyrus	75.13	0.00e+00	892.00
IUUC-Rno-106086	Rattus norvegicus	75.97	0.00e+00	935.00
IUUC-Sha-107245	Sarcophilus harrisii	78.49	0.00e+00	966.00
IUUC-Sar-112985	Sorex araneus	76.79	0.00e+00	949.00
IUUC-Ssc-115756	Sus scrofa	77.48	0.00e+00	951.00
IUUC-Tgu-116838	Taeniopygia guttata	54.95	8.00e-119	420.00
IUUC-Tru-117644	Takifugu rubripes	93.14	0.00e+00	1157.00
IUUC-Tni-120245	Tetraodon nigroviridis	93.25	0.00e+00	1141.00
IUUC-Tbe-127472	Tupaia belangeri	77.64	4.00e-115	409.00
IUUC-Ttr-128953	Tursiops truncatus	77.13	3.00e-144	505.00
IUUC-Vpa-130683	Vicugna pacos	75.84	0.00e+00	843.00
IUUC-Xtr-132827	Xenopus tropicalis	71.26	0.00e+00	881.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence