iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033901

Ensembl Protein ID

ENSECAP00000012992.1

UniProt Accession

F7CVF5; F7CVF5_HORSE

Protein Name

Coronin

Gene Name

CORO1B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000014882.1	ENSECAT00000016105.1	ENSECAP00000012992.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.00e-16	59.6	80	111

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWD 29
           gHt++v ++++   +d  ++sGs D+t++vW 
   Q: 80   GHTGPVLDIDWcphNDEVIASGSEDCTVMVWQ 111
           8***********977799*************7 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MSFRKVVRQS KFRHVFGQPV KNDQCYEDIR VSRVTWDSTF CAVNPKFLAV IVEASGGGAF 60
LVLPLSKTGR IDKAYPTVCG HTGPVLDIDW CPHNDEVIAS GSEDCTVMVW QIPENGLAAP 120

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Nucleotide Sequence
(Fasta)

GGGCAGGGCT GACCCAGGCT TCTGCGCCCT GCAGACATGT CCTTCCGCAA AGTGGTTCGC 60
CAGAGCAAAT TCCGGCATGT GTTCGGGCAG CCGGTCAAGA ATGATCAGTG CTATGAGGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR015505--Coronin
IPR015048--DUF1899
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08953--DUF1899
PF00400--WD40

SMART

SM01166--DUF1899
SM00320--WD40

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005884--C:actin filament
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0001725--C:stress fiber
GO:0051015--F:actin filament binding
GO:0030036--P:actin cytoskeleton organization
GO:0090135--P:actin filament branching
GO:0051017--P:actin filament bundle assembly
GO:0036120--P:cellular response to platelet-derived growth factor stimulus
GO:0035767--P:endothelial cell chemotaxis
GO:0034316--P:negative regulation of Arp2/3 complex-mediated actin nucleation
GO:0071672--P:negative regulation of smooth muscle cell chemotaxis
GO:2000394--P:positive regulation of lamellipodium morphogenesis
GO:1902463--P:protein localization to cell leading edge
GO:0031529--P:ruffle organization
GO:0042060--P:wound healing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002423	Ailuropoda melanoleuca	95.50	0.00e+00	951.00
IUUC-Aca-005056	Anolis carolinensis	80.61	0.00e+00	808.00
IUUC-Bta-012984	Bos taurus	93.84	0.00e+00	937.00
IUUC-Cja-019498	Callithrix jacchus	93.67	0.00e+00	928.00
IUUC-Cfa-020937	Canis familiaris	96.15	0.00e+00	869.00
IUUC-Cpo-021866	Cavia porcellus	89.98	0.00e+00	894.00
IUUC-Csa-023561	Chlorocebus sabaeus	93.87	0.00e+00	938.00
IUUC-Dno-029770	Dasypus novemcinctus	87.37	0.00e+00	866.00
IUUC-Dor-030989	Dipodomys ordii	92.23	0.00e+00	900.00
IUUC-Fca-036494	Felis catus	95.09	0.00e+00	909.00
IUUC-Fal-036737	Ficedula albicollis	82.58	0.00e+00	829.00
IUUC-Ggo-045035	Gorilla gorilla	94.68	0.00e+00	943.00
IUUC-Hsa-046154	Homo sapiens	94.48	0.00e+00	942.00
IUUC-Itr-048847	Ictidomys tridecemlineatus	89.60	0.00e+00	900.00
IUUC-Laf-054566	Loxodonta africana	93.25	0.00e+00	890.00
IUUC-Mcc-054879	Macaca mulatta	94.07	0.00e+00	938.00
IUUC-Mmr-060910	Microcebus murinus	92.86	0.00e+00	926.00
IUUC-Mmu-063455	Mus musculus	93.25	0.00e+00	933.00
IUUC-Mpu-066350	Mustela putorius furo	94.89	0.00e+00	922.00
IUUC-Mlu-067353	Myotis lucifugus	95.88	0.00e+00	928.00
IUUC-Nle-069161	Nomascus leucogenys	94.07	0.00e+00	930.00
IUUC-Opr-071106	Ochotona princeps	92.02	0.00e+00	897.00
IUUC-Oga-088805	Otolemur garnettii	92.64	0.00e+00	930.00
IUUC-Ptr-091484	Pan troglodytes	94.48	0.00e+00	942.00
IUUC-Pan-091843	Papio anubis	93.87	0.00e+00	930.00
IUUC-Pab-097835	Pongo abelii	94.48	0.00e+00	938.00
IUUC-Pca-100411	Procavia capensis	81.19	0.00e+00	786.00
IUUC-Pva-102659	Pteropus vampyrus	95.71	0.00e+00	936.00
IUUC-Rno-106070	Rattus norvegicus	92.84	0.00e+00	932.00
IUUC-Sha-106609	Sarcophilus harrisii	93.80	0.00e+00	707.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence