iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074296

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02023185

Gene Name

UBA6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000012827.2	ENSOCUT00000012840.2	ENSOCUP00000011048.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	2.10e-221	735.4	443	930

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv......gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealke 83
           YD +++++G + ++kl++ +++lvG+g++GcE+lKn++l+Gv      g++tv+D d +e+snlnrqFLfr+ +++k+K+ +aa+a  +
   Q: 443  YDALRACIGNTLCQKLQNLNIFLVGCGAIGCEMLKNFALLGVgtskekGMVTVTDPDLIEKSNLNRQFLFRPYHIQKPKSYTAADATLK 531
           9**************************************************************************************** PP
   S: 84   lnpdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqk 169
           +np+ +++ah +++++ +e+i+   F++k d++++aldn+earr+v+++cl++ +pl++sgt+G++G+++vi+++lte+y++++dpp++
   Q: 532  INPQLKIDAHLNKVCPATETIYndeFYTKQDIIITALDNVEARRYVDSRCLANLRPLLDSGTMGTKGHTEVIVPHLTESYNSHRDPPEE 620
           ***************************************************************************************** PP
   S: 170  tiPfctlketpnaaehtiewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafa 246
           +iPfctlk++p+a+ehti+wa            +lfnk++++++++e+vl+k+++ +++eg+++v  +l s++++n+++++e+a+ +f+
   Q: 621  EIPFCTLKSFPAAIEHTIQWArdkfessfshkpSLFNKFWQTYPSAEDVLQKMQNGHSLEGCFQV-IKLLSRRPRNWSQCVELARLKFE 708
           *****************************************************************.999******************** PP
   S: 247  kttinsikqllksfecdivtkskspfwv.........................................................sfcs 278
           k++++++ qll++f+ d + k++s fw+                                                         +f++
   Q: 709  KYFNHKALQLLHCFPLDTRLKDGSLFWQspkrppspikfdlneplhlsflqnaaklyatvycipfteeglsadalqnilaevkieEFKP 797
           ***************************************************************************************** PP
   S: 279  naealqvpekvekdeevvkasap.....lylllralerfekkkgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlike 360
            ++ +q++e++ k+e+v  +s++     ++l++++ ++ ++k+++++++lsfekddds  ++d++taa+nlra++++iep +d++++k+
   Q: 798  SNKVVQTDETARKPEHVPVSSEDernavFQLEKAISSNEATKSDLQMAVLSFEKDDDSngHIDFITAASNLRAKMYSIEP-ADRFKTKR 885
           ****************998888899*******************************************************.******** PP
   S: 361  iagniipaiattnavvgGlaaqEviKvvsg.kfeplknfflfdae 404
           iag+iipaiat +a+v+Gl+a+E+iKv+ g +fe++kn+fl++a+
   Q: 886  IAGKIIPAIATSTAAVSGLVALEMIKVAGGyPFEAYKNCFLNLAI 930
           *****************************************9886 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MEGSESVAAP REEAASCSSW GSGSTSKNFT IMSAESVEID DALYSRQRYV LGDTAMQKMA 60
KSHVFLSGMG GLGLEIAKNL VLAGIKALTI HDTEKCQAWD LGTNFFLCED DVINMKNRAE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGGGGT CCGAGTCGGT CGCAGCGCCG CGGGAGGAAG CAGCATCCTG TTCTTCCTGG 60
GGGTCCGGCA GGTGAGAGGA CATTGTGGCT ACGAAGAAGC AGAGTCACAG GCAGGACCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR000011--UBQ/SUMO-activ_enz_E1-like

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005737--C:cytoplasm
GO:0019780--F:FAT10 activating enzyme activity
GO:0004839--F:ubiquitin activating enzyme activity
GO:0021764--P:amygdala development
GO:0060996--P:dendritic spine development
GO:0021766--P:hippocampus development
GO:0007612--P:learning
GO:0007626--P:locomotory behavior
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001608	Ailuropoda melanoleuca	93.35	0.00e+00	2055.00
IUUC-Apl-004158	Anas platyrhynchos	80.58	0.00e+00	1744.00
IUUC-Aca-005349	Anolis carolinensis	80.22	0.00e+00	1770.00
IUUC-Bta-012696	Bos taurus	91.35	0.00e+00	2017.00
IUUC-Cja-019563	Callithrix jacchus	92.78	0.00e+00	2028.00
IUUC-Cfa-020951	Canis familiaris	92.78	0.00e+00	2050.00
IUUC-Cpo-022307	Cavia porcellus	88.70	0.00e+00	1940.00
IUUC-Csa-023647	Chlorocebus sabaeus	93.25	0.00e+00	2045.00
IUUC-Cho-024682	Choloepus hoffmanni	76.49	0.00e+00	931.00
IUUC-Dre-028022	Danio rerio	67.68	0.00e+00	1487.00
IUUC-Dno-029796	Dasypus novemcinctus	90.56	0.00e+00	1946.00
IUUC-Dor-030981	Dipodomys ordii	76.79	0.00e+00	1532.00
IUUC-Ete-032514	Echinops telfairi	77.70	0.00e+00	1143.00
IUUC-Eca-033697	Equus caballus	93.20	0.00e+00	2015.00
IUUC-Eeu-035323	Erinaceus europaeus	83.51	0.00e+00	1353.00
IUUC-Fca-035858	Felis catus	93.68	0.00e+00	2027.00
IUUC-Fal-036848	Ficedula albicollis	80.51	0.00e+00	1738.00
IUUC-Gmo-039326	Gadus morhua	66.57	0.00e+00	1394.00
IUUC-Gga-040747	Gallus gallus	80.90	0.00e+00	1731.00
IUUC-Gac-041406	Gasterosteus aculeatus	67.22	0.00e+00	1402.00
IUUC-Ggo-044577	Gorilla gorilla	93.07	0.00e+00	2039.00
IUUC-Hsa-046007	Homo sapiens	93.06	0.00e+00	2031.00
IUUC-Itr-048191	Ictidomys tridecemlineatus	94.38	0.00e+00	1066.00
IUUC-Lch-049992	Latimeria chalumnae	73.39	0.00e+00	1550.00
IUUC-Loc-051899	Lepisosteus oculatus	69.35	0.00e+00	1495.00
IUUC-Laf-054413	Loxodonta africana	92.21	0.00e+00	1877.00
IUUC-Mcc-054656	Macaca mulatta	93.25	0.00e+00	2041.00
IUUC-Meu-056463	Macropus eugenii	72.77	0.00e+00	1444.00
IUUC-Mga-059721	Meleagris gallopavo	78.95	0.00e+00	1637.00
IUUC-Mmr-060908	Microcebus murinus	89.35	0.00e+00	1958.00
IUUC-Mdo-062096	Monodelphis domestica	84.67	0.00e+00	1897.00
IUUC-Mmu-064114	Mus musculus	89.73	0.00e+00	1963.00
IUUC-Mpu-066017	Mustela putorius furo	92.59	0.00e+00	2051.00
IUUC-Mlu-068037	Myotis lucifugus	89.70	0.00e+00	1951.00
IUUC-Nle-069494	Nomascus leucogenys	92.49	0.00e+00	2024.00
IUUC-Opr-070910	Ochotona princeps	69.02	0.00e+00	630.00
IUUC-Ont-071592	Oreochromis niloticus	68.04	0.00e+00	1451.00
IUUC-Oan-073268	Ornithorhynchus anatinus	80.16	0.00e+00	1594.00
IUUC-Ola-086376	Oryzias latipes	68.27	0.00e+00	1403.00
IUUC-Oga-088186	Otolemur garnettii	92.21	0.00e+00	2012.00
IUUC-Oar-089307	Ovis aries	91.54	0.00e+00	2020.00
IUUC-Ptr-090609	Pan troglodytes	93.25	0.00e+00	2033.00
IUUC-Pan-092905	Papio anubis	92.96	0.00e+00	1946.00
IUUC-Psi-093489	Pelodiscus sinensis	81.78	0.00e+00	1768.00
IUUC-Pma-094203	Petromyzon marinus	67.57	1.00e-58	218.00
IUUC-Pfo-096670	Poecilia formosa	68.79	0.00e+00	1462.00
IUUC-Pab-098418	Pongo abelii	92.87	0.00e+00	2026.00
IUUC-Pca-100889	Procavia capensis	74.52	0.00e+00	1573.00
IUUC-Pva-103144	Pteropus vampyrus	80.99	0.00e+00	1749.00
IUUC-Rno-105612	Rattus norvegicus	90.21	0.00e+00	1975.00
IUUC-Sha-107388	Sarcophilus harrisii	87.11	0.00e+00	1886.00
IUUC-Sar-113128	Sorex araneus	88.98	0.00e+00	1928.00
IUUC-Ssc-116117	Sus scrofa	92.12	0.00e+00	2034.00
IUUC-Tgu-116565	Taeniopygia guttata	80.92	0.00e+00	1750.00
IUUC-Tru-118591	Takifugu rubripes	67.25	0.00e+00	1410.00
IUUC-Tsy-119436	Tarsius syrichta	81.46	0.00e+00	1755.00
IUUC-Tni-120880	Tetraodon nigroviridis	66.67	0.00e+00	1402.00
IUUC-Tbe-127714	Tupaia belangeri	79.54	0.00e+00	1403.00
IUUC-Ttr-129159	Tursiops truncatus	80.32	0.00e+00	1698.00
IUUC-Vpa-130716	Vicugna pacos	90.27	0.00e+00	1899.00
IUUC-Xtr-132947	Xenopus tropicalis	70.05	0.00e+00	1526.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence