iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033808

UUCD1 version

UUC-EqC-00820

Ensembl Protein ID

ENSECAP00000012967.1

UniProt Accession

F7CW58; F7CW58_HORSE

Protein Name

Uncharacterized protein

Gene Name

RNF122

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000015301.1	ENSECAT00000016076.1	ENSECAP00000012967.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.20e-08	34.2	93	134

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+Cledf  kd++ vlpC+H+fh++Cl kw         +  CP C+
   Q: 93   CAVCLEDFkgKDELGVLPCQHAFHRKCLVKW------LEVRCVCPMCN 134
           ********99778******************......999999****7 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MHPFQWCNGC FCGLGLVSTN KSCSMPPISF QDLPLNIYMV IFGTGIFIFM LSLIFCCYFI 60
SKLRNQAQSE RYGYKEVVLK GDAKKLQLYG QTCAVCLEDF KGKDELGVLP CQHAFHRKCL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAAGCCAGC CGAGAGGTCA TTGATGCACC CATTCCAGTG GTGTAACGGT GAGTCCCCGG 60
GCGGGAGGGC GAGCGGGCGC TGGGCTGGCT GGAGAGGCGG AGGGGTGCGC AAGCCTGAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

ecb:100060999

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002066	Ailuropoda melanoleuca	98.06	2.00e-88	317.00
IUUC-Apl-003691	Anas platyrhynchos	83.46	2.00e-65	240.00
IUUC-Aca-004989	Anolis carolinensis	90.32	7.00e-83	298.00
IUUC-Ame-011731	Astyanax mexicanus	82.58	1.00e-77	281.00
IUUC-Bta-012760	Bos taurus	97.28	1.00e-80	291.00
IUUC-Cja-019442	Callithrix jacchus	97.42	4.00e-88	316.00
IUUC-Cfa-021257	Canis familiaris	94.19	4.00e-83	299.00
IUUC-Cpo-021821	Cavia porcellus	90.51	2.00e-81	294.00
IUUC-Cre-022857	Chlamydomonas reinhardtii	42.59	7.00e-09	55.50
IUUC-Csa-023926	Chlorocebus sabaeus	97.42	4.00e-88	316.00
IUUC-Cho-024763	Choloepus hoffmanni	94.68	6.00e-50	187.00
IUUC-Cme-027308	Cyanidioschyzon merolae	36.00	6.00e-09	56.20
IUUC-Dre-028547	Danio rerio	83.23	8.00e-78	281.00
IUUC-Dno-029352	Dasypus novemcinctus	98.06	3.00e-88	316.00
IUUC-Dor-030113	Dipodomys ordii	97.87	4.00e-51	191.00
IUUC-Ete-032590	Echinops telfairi	83.23	5.00e-74	269.00
IUUC-Eeu-035101	Erinaceus europaeus	96.58	3.00e-80	290.00
IUUC-Fca-035925	Felis catus	98.71	1.00e-88	318.00
IUUC-Gmo-038545	Gadus morhua	88.39	4.00e-80	289.00
IUUC-Gga-041003	Gallus gallus	80.65	8.00e-74	268.00
IUUC-Gac-042633	Gasterosteus aculeatus	61.31	3.00e-41	160.00
IUUC-Hsa-047006	Homo sapiens	97.42	7.00e-88	315.00
IUUC-Itr-048723	Ictidomys tridecemlineatus	96.13	4.00e-86	309.00
IUUC-Loc-052517	Lepisosteus oculatus	89.80	2.00e-75	274.00
IUUC-Laf-053986	Loxodonta africana	96.77	7.00e-86	308.00
IUUC-Mcc-054860	Macaca mulatta	95.36	2.00e-81	294.00
IUUC-Meu-056640	Macropus eugenii	80.56	2.00e-61	227.00
IUUC-Mla-059067	Melampsora laricipopulina	39.53	2.00e-08	54.30
IUUC-Mmr-061260	Microcebus murinus	97.22	2.00e-78	283.00
IUUC-Mdo-062793	Monodelphis domestica	90.48	9.00e-77	278.00
IUUC-Mmu-063949	Mus musculus	97.42	3.00e-88	316.00
IUUC-Mpu-066068	Mustela putorius furo	98.71	1.00e-88	318.00
IUUC-Mlu-067176	Myotis lucifugus	98.06	4.00e-88	316.00
IUUC-Nle-069924	Nomascus leucogenys	96.13	9.00e-87	311.00
IUUC-Opr-070985	Ochotona princeps	96.77	6.00e-86	308.00
IUUC-Ont-071718	Oreochromis niloticus	62.77	7.00e-43	166.00
IUUC-Oan-073727	Ornithorhynchus anatinus	89.73	3.00e-76	276.00
IUUC-Ocu-074776	Oryctolagus cuniculus	96.71	1.00e-84	304.00
IUUC-Obr-076171	Oryza brachyantha	44.26	4.00e-12	64.70
IUUC-Ome-081724	Oryza meridionalis	46.15	2.00e-11	64.30
IUUC-Ola-087147	Oryzias latipes	87.74	4.00e-80	289.00
IUUC-Oga-087917	Otolemur garnettii	98.06	1.00e-88	317.00
IUUC-Oar-089739	Ovis aries	94.81	1.00e-83	301.00
IUUC-Ptr-090619	Pan troglodytes	97.42	7.00e-88	315.00
IUUC-Pan-092854	Papio anubis	97.42	4.00e-88	316.00
IUUC-Psi-093254	Pelodiscus sinensis	90.40	3.00e-66	244.00
IUUC-Pma-094708	Petromyzon marinus	67.11	2.00e-24	103.00
IUUC-Pfo-096899	Poecilia formosa	87.74	5.00e-80	289.00
IUUC-Pab-097858	Pongo abelii	98.06	2.00e-88	317.00
IUUC-Pca-100210	Procavia capensis	97.42	9.00e-88	315.00
IUUC-Pva-102677	Pteropus vampyrus	96.77	5.00e-86	309.00
IUUC-Rno-105488	Rattus norvegicus	83.21	1.00e-58	218.00
IUUC-Sha-107332	Sarcophilus harrisii	90.54	1.00e-77	280.00
IUUC-Sar-113175	Sorex araneus	93.52	7.00e-57	211.00
IUUC-Ssc-115896	Sus scrofa	98.06	9.00e-87	311.00
IUUC-Tru-118255	Takifugu rubripes	79.35	8.00e-69	251.00
IUUC-Tsy-119575	Tarsius syrichta	98.06	2.00e-88	317.00
IUUC-Tni-120329	Tetraodon nigroviridis	76.77	2.00e-66	244.00
IUUC-Ttr-128649	Tursiops truncatus	98.06	4.00e-88	316.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence