iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093707

Ensembl Protein ID

ENSPSIP00000004375.1

UniProt Accession

K7F8L5; K7F8L5_PELSI

Genbank Protein ID

ENSPSIP00000004375

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01145911

Gene Name

USP35

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000004110.1	ENSPSIT00000004398.1	ENSPSIP00000004375.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.60e-83	280.8	446	896

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl NlgNtCYmNS++Q+L++ +++r+ +l+     l e+    ++++l+++lq lf+ l +s++ a+sp+++l+a +   + fs  +qq
   Q: 446  GLINLGNTCYMNSIIQALFMASDFRHSVLN-----LTES----NSQPLMTKLQWLFAFLEHSQRPAISPESFLSASW--PPWFSPGAQQ 523
           9*****************************.....4433....3679***************************987..788******* PP
   S: 91   DaqEflaflldq..leeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvp 177
           D++E+l++lld+  l+ee  k  +  +++++e+      +++ e+++  nk+li+++F+g+++++i+cl+c nvssree f+dlsl++p
   Q: 524  DCSEYLKYLLDRqrLHEEE-KTGKRIYQKLKES----NLMSQAEEHHYLNKTLIEKMFGGKMTTKIRCLKCLNVSSREEAFTDLSLAFP 607
           **********963377777.2233444444333....3455668899****************************************** PP
   S: 178  gkeetkke................................................................................. 185
            ++   ++                                                                                 
   Q: 608  PSNRHMHRqshiiepsiqpqnqvvesprrqrkhpvsgehpihllpvetvgfqkpegeetpfsltpnrdpihaeavkdpllafgeqtcgs 696
           88865555899****************************************************************************** PP
   S: 186  ....slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspee 270
               s+ d+++ f ++e l++enky+cekc ++q+aek  +l++ P++Lil L Rfsf+ ++++r+ki ++v++pl L+l   ++s+e+
   Q: 697  dssrSVPDLINYFLSPEVLTSENKYHCEKCASLQDAEKVAELTEGPHYLILTLLRFSFDLRTMRRKKILDNVSIPLVLKLPVLVASEES 785
           ********************************************************************************987777554 PP
   S: 271  kqke...............kkkYeLiavvvHsG.slssGHYvayvkn........................ekgkWllfdDskVtevke 319
           ++ +               +  Y+L++vvvHsG s++sGHY++y+++                         + +W+lf+D++V+ ++ 
   Q: 786  GE-VcqnrkdraascsgfvSMVYDLCSVVVHSGvSSESGHYYCYAREcastsarsqpsdgaqesasdkqldFEIQWYLFNDTRVSFSSF 873
           43.3578889999999999************************************99999999887766555666************** PP
   S: 320  eevleetg....staYvlfYkrr 338
           e+v + t+    +taYvlfY++r
   Q: 874  ESVSNVTSffpkDTAYVLFYRQR 896
           *****999************985 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MDKILEAVMM SSYPNNVKQG LVRRVIEAIK QPMDSEQCWS MLELSTKLYL MGDTKFKREI 60
GKEILEVYGH YHLEEFEEFF NVRFLLSLLQ EGYGPAGKRS FYVLDYIHLG LQFILESPSA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACAAGA TACTAGAAGC GGTGATGATG TCTTCATATC CCAACAACGT GAAACAAGGG 60
CTAGTGAGAC GCGTCATAGA AGCAATAAAG CAGCCCATGG ACAGTGAGCA GTGCTGGTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR033840--USP38
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-004121	Anas platyrhynchos	84.57	0.00e+00	1543.00
IUUC-Aca-005070	Anolis carolinensis	69.57	0.00e+00	950.00
IUUC-Bta-012545	Bos taurus	67.12	0.00e+00	889.00
IUUC-Cja-019731	Callithrix jacchus	66.62	0.00e+00	874.00
IUUC-Cfa-020095	Canis familiaris	67.76	0.00e+00	901.00
IUUC-Cpo-021961	Cavia porcellus	64.25	0.00e+00	1009.00
IUUC-Csa-023167	Chlorocebus sabaeus	60.69	0.00e+00	1014.00
IUUC-Cin-025604	Ciona intestinalis	29.51	1.00e-44	173.00
IUUC-Dno-029186	Dasypus novemcinctus	67.13	0.00e+00	640.00
IUUC-Dor-030538	Dipodomys ordii	71.59	0.00e+00	769.00
IUUC-Dme-031871	Drosophila melanogaster	33.23	5.00e-46	179.00
IUUC-Eeu-035120	Erinaceus europaeus	50.82	0.00e+00	628.00
IUUC-Fal-037625	Ficedula albicollis	83.25	0.00e+00	1571.00
IUUC-Gga-040767	Gallus gallus	82.69	0.00e+00	1587.00
IUUC-Hsa-046124	Homo sapiens	69.87	0.00e+00	870.00
IUUC-Itr-048704	Ictidomys tridecemlineatus	64.97	0.00e+00	1142.00
IUUC-Lch-049513	Latimeria chalumnae	63.78	0.00e+00	1162.00
IUUC-Loc-052698	Lepisosteus oculatus	59.37	0.00e+00	1098.00
IUUC-Laf-053999	Loxodonta africana	65.06	0.00e+00	1167.00
IUUC-Mcc-055266	Macaca mulatta	65.29	0.00e+00	850.00
IUUC-Meu-056906	Macropus eugenii	76.49	0.00e+00	1054.00
IUUC-Mga-059595	Meleagris gallopavo	82.68	0.00e+00	1589.00
IUUC-Mdo-062167	Monodelphis domestica	72.74	0.00e+00	1352.00
IUUC-Mmu-063298	Mus musculus	67.26	0.00e+00	889.00
IUUC-Mpu-066195	Mustela putorius furo	68.30	0.00e+00	897.00
IUUC-Opr-070454	Ochotona princeps	60.29	2.00e-110	393.00
IUUC-Ocu-074121	Oryctolagus cuniculus	60.27	0.00e+00	986.00
IUUC-Oga-088593	Otolemur garnettii	64.68	0.00e+00	1107.00
IUUC-Oar-090140	Ovis aries	66.82	0.00e+00	878.00
IUUC-Pan-092168	Papio anubis	60.79	0.00e+00	1014.00
IUUC-Pma-094349	Petromyzon marinus	46.23	0.00e+00	789.00
IUUC-Pab-097614	Pongo abelii	69.71	0.00e+00	867.00
IUUC-Pca-100683	Procavia capensis	63.46	0.00e+00	855.00
IUUC-Rno-105061	Rattus norvegicus	66.96	0.00e+00	889.00
IUUC-Sha-106686	Sarcophilus harrisii	75.74	0.00e+00	1040.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence