iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-013544

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02044378

Gene Name

USP38

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000001356.4	ENSBTAT00000001785.4	ENSBTAP00000001785.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.30e-83	279.4	445	947

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           tGl NlgNtCYmNSv+Q+L++ +++r+++l+ + + +n         +l+k+lq+lf+ l +++++a++pr +++a +   + f+  +q
   Q: 445  TGLINLGNTCYMNSVIQALFMATDFRRQVLSLNLNGCN---------SLMKKLQHLFAFLAHTQREAYAPRIFFEASR--PPWFTPRSQ 522
           7******************************5555554.........7***************************998..777****** PP
   S: 90   qDaqEflaflldqleeelkk...eknkpkeeeeeedkselsde........aeekkkkknkslisdlFqgqlksqikclecdnvssree 167
           qD++E+l+flld+l+ee k    +++++ +e+ + ++++l++         +   +   +k+li+++F+g+l+++i cl+c+++s++ e
   Q: 523  QDCSEYLRFLLDRLHEEEKIlkvQSSHKSSESPGCSETSLQEVankaavltETHCTSDGEKTLIEKMFGGKLRTHICCLNCRSTSQKVE 611
           *****************95577677888888888888888888888888877777888888**************************** PP
   S: 168  pfldlslpvpgkeetkke....................................................................... 185
            f+dlsl++  +++++++                                                                       
   Q: 612  AFTDLSLAFCPSSSMENLsfqdpasspstqddgltqasgpgpskepgvcnasavaiacdsavnermvdspdefcctedtsvpndsskml 700
           **********999887779********************************************************************** PP
   S: 186  ...............slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleL 259
                          s++d+L+ f ++e l+g+n+yyce+c ++q+aek++++++ Pe+Lil L Rfs++++ ++r+ki ++v++pl L
   Q: 701  vnkdvpqkpggettpSVTDLLNYFLAPEILTGDNQYYCENCASLQNAEKTMQITEEPEYLILTLLRFSYDQKYHVRRKILDNVSLPLVL 789
           ***************************************************************************************99 PP
   S: 260  dlspfcts..............................peekqke.....kkkYeLiavvvHsG.slssGHYvayvkn........... 301
           +l    t                               +     e      + Y L++vvvHsG s++sGHY++y++n           
   Q: 790  ELPVKRTPfsslseswsldvdftdisenlakklkpsgtE-----EacspkLVPYLLSSVVVHSGvSSESGHYYSYARNvtgtesscqmc 873
           998444445555666666666666666666666555553.....0555559************************************** PP
   S: 302  .................................ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
                                             +++W+lf+Ds+Vt ++ ++v++ t+    +taYvl+Ykr+
   Q: 874  pqpetlafsssrnhllgresptvvieqdlenkdMSKEWFLFNDSRVTFTSFQSVQKITSrfpkDTAYVLLYKRQ 947
           **********999999999999999988865544555*******************999*************96 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MDKILEGLVS SSHPLPLKRV IVRKVVESAE HWLDEAQCEA MFDLTTRLIL EGQDPFQRQV 60
GHQVLEAYAR YHRPEFESFF NKTFVLGLLQ QGYHSLDRKD VAIVDYIHNG LKLIMSCPSV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGGCACCTT TCGTGACAGC CGCTTCTGAC TCAACCCAGG CTGGGTTTCA TCCCAGGACC 60
GGCTGGAGCC CGAACGCCTG CACCTGCTGC GGCACGCGGA GGCGCGCTTC CTCACCCGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033840--USP38
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002174	Ailuropoda melanoleuca	92.73	0.00e+00	1832.00
IUUC-Apl-003435	Anas platyrhynchos	76.36	0.00e+00	1273.00
IUUC-Aca-004556	Anolis carolinensis	70.69	0.00e+00	1276.00
IUUC-Ame-010616	Astyanax mexicanus	62.18	0.00e+00	1201.00
IUUC-Cja-018745	Callithrix jacchus	90.82	0.00e+00	1808.00
IUUC-Cfa-020434	Canis familiaris	89.16	0.00e+00	1773.00
IUUC-Cpo-021666	Cavia porcellus	90.78	0.00e+00	1746.00
IUUC-Csa-023965	Chlorocebus sabaeus	93.09	0.00e+00	1908.00
IUUC-Cho-024809	Choloepus hoffmanni	82.89	0.00e+00	1235.00
IUUC-Cin-025604	Ciona intestinalis	30.05	1.00e-41	163.00
IUUC-Csv-026333	Ciona savignyi	43.68	7.00e-31	127.00
IUUC-Dre-028338	Danio rerio	62.58	0.00e+00	1217.00
IUUC-Dno-029372	Dasypus novemcinctus	91.46	0.00e+00	1822.00
IUUC-Dor-030752	Dipodomys ordii	88.02	0.00e+00	1236.00
IUUC-Dme-031871	Drosophila melanogaster	30.32	4.00e-46	179.00
IUUC-Ete-032588	Echinops telfairi	79.61	0.00e+00	1121.00
IUUC-Eca-034416	Equus caballus	94.15	0.00e+00	1905.00
IUUC-Eeu-035132	Erinaceus europaeus	73.85	0.00e+00	1386.00
IUUC-Fca-036137	Felis catus	93.28	0.00e+00	1884.00
IUUC-Fal-037297	Ficedula albicollis	75.55	0.00e+00	1457.00
IUUC-Gmo-038727	Gadus morhua	65.74	0.00e+00	1015.00
IUUC-Gga-041091	Gallus gallus	74.24	0.00e+00	1410.00
IUUC-Gac-042082	Gasterosteus aculeatus	62.99	0.00e+00	1134.00
IUUC-Ggo-045376	Gorilla gorilla	87.95	0.00e+00	1735.00
IUUC-Hsa-046444	Homo sapiens	92.80	0.00e+00	1877.00
IUUC-Itr-047976	Ictidomys tridecemlineatus	91.75	0.00e+00	1835.00
IUUC-Lch-050500	Latimeria chalumnae	72.02	0.00e+00	1397.00
IUUC-Loc-052625	Lepisosteus oculatus	65.17	0.00e+00	1288.00
IUUC-Laf-053689	Loxodonta africana	92.69	0.00e+00	1847.00
IUUC-Mcc-055286	Macaca mulatta	92.90	0.00e+00	1857.00
IUUC-Mga-059905	Meleagris gallopavo	74.64	0.00e+00	1244.00
IUUC-Mmr-061397	Microcebus murinus	93.47	0.00e+00	1866.00
IUUC-Mdo-062833	Monodelphis domestica	85.93	0.00e+00	1758.00
IUUC-Mmu-063157	Mus musculus	89.06	0.00e+00	1803.00
IUUC-Mpu-066434	Mustela putorius furo	93.67	0.00e+00	1874.00
IUUC-Mlu-068178	Myotis lucifugus	91.50	0.00e+00	1789.00
IUUC-Nle-070153	Nomascus leucogenys	92.23	0.00e+00	1811.00
IUUC-Ont-072330	Oreochromis niloticus	62.67	0.00e+00	1214.00
IUUC-Oan-072709	Ornithorhynchus anatinus	81.40	0.00e+00	1279.00
IUUC-Ocu-074832	Oryctolagus cuniculus	92.99	0.00e+00	1853.00
IUUC-Ola-087003	Oryzias latipes	55.21	2.00e-46	177.00
IUUC-Oga-088517	Otolemur garnettii	89.39	0.00e+00	1785.00
IUUC-Oar-089472	Ovis aries	95.29	0.00e+00	1910.00
IUUC-Ptr-090996	Pan troglodytes	92.51	0.00e+00	1870.00
IUUC-Pan-091837	Papio anubis	91.04	0.00e+00	1832.00
IUUC-Psi-093236	Pelodiscus sinensis	76.78	0.00e+00	1173.00
IUUC-Pma-094349	Petromyzon marinus	52.81	0.00e+00	962.00
IUUC-Pfo-097193	Poecilia formosa	63.03	0.00e+00	1164.00
IUUC-Pab-098710	Pongo abelii	92.51	0.00e+00	1880.00
IUUC-Pca-100794	Procavia capensis	81.59	0.00e+00	1603.00
IUUC-Pva-102722	Pteropus vampyrus	92.91	0.00e+00	1849.00
IUUC-Rno-105743	Rattus norvegicus	89.05	0.00e+00	1787.00
IUUC-Sha-106563	Sarcophilus harrisii	84.79	0.00e+00	1417.00
IUUC-Sar-113533	Sorex araneus	77.91	0.00e+00	1539.00
IUUC-Ssc-116259	Sus scrofa	84.20	0.00e+00	1572.00
IUUC-Tgu-117475	Taeniopygia guttata	75.21	0.00e+00	1312.00
IUUC-Tru-118623	Takifugu rubripes	62.37	0.00e+00	1147.00
IUUC-Tsy-119250	Tarsius syrichta	91.28	0.00e+00	1448.00
IUUC-Tni-120441	Tetraodon nigroviridis	58.68	0.00e+00	1063.00
IUUC-Tbe-127936	Tupaia belangeri	80.60	0.00e+00	1539.00
IUUC-Ttr-128483	Tursiops truncatus	82.59	0.00e+00	1448.00
IUUC-Vpa-130303	Vicugna pacos	98.50	0.00e+00	1078.00
IUUC-Xtr-132773	Xenopus tropicalis	72.62	0.00e+00	1402.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence