iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oga-088517

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03074315

Gene Name

USP38

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000003985.2	ENSOGAT00000003988.2	ENSOGAP00000003550.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.90e-69	234.4	494	962

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgye 88
           tGl NlgNtCYmNSv+Q+L++ +++r+++l+ + + +n         +l+k+lq+lf+ l  ++k++a++pr +++a +   + f+  +
   Q: 494  TGLINLGNTCYMNSVIQALFMATDFRRQVLSLNLNGCN---------SLMKKLQHLFAFLAhTQKREAYAPRIFFEASR--PPWFTPRS 571
           7******************************5555554.........7************9888999*********998..777***** PP
   S: 89   qqDaqEflaflldqleeelkk...eknkpkeeeeeedkselsde........aeekkkkknkslisdlFqgqlksqikclecdnvssre 166
           qqD++E+l+flld+l+ee k    ++ ++  e+ + ++++l++         + +     +k+li+++F+g+l+++i cl+c+++s++ 
   Q: 572  QQDCSEYLRFLLDRLHEEEKIlkvQSAHKSPESLGYSETSLQEVdskaavltETSCIIDGEKTLIEKMFGGKLQTHICCLNCGSTSQKV 660
           ******************95566655555555556666666665667777767777777888*************************** PP
   S: 167  epfldlslpvpgkeetkke...................................................................... 185
           e f+dlsl++  +++++++                                                                      
   Q: 661  EAFTDLSLAFCPSSSMENLsfqgpasspstqgsdlmqptvpgpseepvvynpataaficdsvvnerigssldefyctentsipnesdkn 749
           ***********999887779********************************************************************* PP
   S: 186  ................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple 258
                           s++d+L+ f ++e l+g+n+yyce+c ++q+aek++++++ Pe+Lil L Rfs++++ ++r+ki ++v++pl 
   Q: 750  lvnedvpqkpggettpSVTDLLNYFLAPEILTGDNQYYCENCASLQNAEKTMQITEEPEYLILTLLRFSYDQKYHVRRKILDNVSLPLV 838
           ***************************************************************************************** PP
   S: 259  Ldlspfcts...............peekqke.....................kkkYeLiavvvHsG.sl..ssGHYvayvkn......e 302
           L+l    t+               +     +                      + Y L++v   s  s+  +    +a++ +       
   Q: 839  LELPVKRTTsfsslseswsvdvgfN-----DtsenlakklkpsgteepccpkLVPYLLSSVALASSqSHllGRESPTAVIEQdlenkeI 922
           9999655553555555555555550.....055555566666666677777799*******9999855411455789999997655444 PP
   S: 303  kgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
           +++W+lf+Ds+Vt ++ ++v++ t+    +taYvl+Yk++
   Q: 923  SKEWFLFNDSRVTFTSFQSVQKITSrfpkDTAYVLLYKKQ 962
           555*******************999************986 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

GGGGGGRSSC CCAPSSPPPR RSLAPSGGCR RPLLIPWPWP CSVVTMDKIL EGLVSSSHPL 60
PLKRVIVRKV VESAEHWLDE AQCEAMFDLT TRLILEGQDP FQRQVGHQVL EAYARYHRPE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTCTGAATC CGGGTCAAGG GTGTTCGCTT TGGTCTCTTC CCTGCTGATT CCGGCACCCT 60
CCGTGACAGC GCCACCTGAC TCAGCCCGGG ACCGGTTTCT TCTCACGACT TGCTGGAGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033840--USP38
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002174	Ailuropoda melanoleuca	88.65	0.00e+00	1805.00
IUUC-Apl-003435	Anas platyrhynchos	73.22	0.00e+00	1229.00
IUUC-Aca-004556	Anolis carolinensis	68.50	0.00e+00	1234.00
IUUC-Ame-010616	Astyanax mexicanus	59.13	0.00e+00	1162.00
IUUC-Bta-013544	Bos taurus	88.62	0.00e+00	1769.00
IUUC-Cja-018745	Callithrix jacchus	90.11	0.00e+00	1786.00
IUUC-Cfa-020434	Canis familiaris	84.72	0.00e+00	1689.00
IUUC-Cpo-021666	Cavia porcellus	87.67	0.00e+00	1708.00
IUUC-Csa-023965	Chlorocebus sabaeus	90.74	0.00e+00	1838.00
IUUC-Cho-024809	Choloepus hoffmanni	79.12	0.00e+00	1163.00
IUUC-Csv-026333	Ciona savignyi	37.39	9.00e-30	123.00
IUUC-Dre-028338	Danio rerio	61.82	0.00e+00	1199.00
IUUC-Dno-029372	Dasypus novemcinctus	87.49	0.00e+00	1749.00
IUUC-Dor-030752	Dipodomys ordii	84.79	0.00e+00	1186.00
IUUC-Dme-031871	Drosophila melanogaster	29.52	2.00e-60	227.00
IUUC-Ete-032588	Echinops telfairi	75.88	0.00e+00	1050.00
IUUC-Eca-034416	Equus caballus	89.90	0.00e+00	1822.00
IUUC-Eeu-035132	Erinaceus europaeus	69.81	0.00e+00	1286.00
IUUC-Fca-036137	Felis catus	89.21	0.00e+00	1776.00
IUUC-Fal-037297	Ficedula albicollis	72.48	0.00e+00	1409.00
IUUC-Gmo-038727	Gadus morhua	65.67	0.00e+00	1000.00
IUUC-Gga-041091	Gallus gallus	71.05	0.00e+00	1349.00
IUUC-Gac-042082	Gasterosteus aculeatus	61.68	0.00e+00	1105.00
IUUC-Ggo-045376	Gorilla gorilla	85.73	0.00e+00	1738.00
IUUC-Hsa-046444	Homo sapiens	89.88	0.00e+00	1813.00
IUUC-Itr-047976	Ictidomys tridecemlineatus	89.30	0.00e+00	1827.00
IUUC-Lch-050500	Latimeria chalumnae	69.02	0.00e+00	1338.00
IUUC-Loc-052625	Lepisosteus oculatus	63.09	0.00e+00	1233.00
IUUC-Laf-053689	Loxodonta africana	89.64	0.00e+00	1776.00
IUUC-Mcc-055286	Macaca mulatta	90.07	0.00e+00	1814.00
IUUC-Mga-059905	Meleagris gallopavo	70.93	0.00e+00	1190.00
IUUC-Mmr-061397	Microcebus murinus	91.88	0.00e+00	1865.00
IUUC-Mdo-062833	Monodelphis domestica	82.86	0.00e+00	1682.00
IUUC-Mmu-063157	Mus musculus	85.96	0.00e+00	1734.00
IUUC-Mpu-066434	Mustela putorius furo	89.68	0.00e+00	1789.00
IUUC-Mlu-068178	Myotis lucifugus	87.35	0.00e+00	1736.00
IUUC-Nle-070153	Nomascus leucogenys	89.78	0.00e+00	1786.00
IUUC-Ont-072330	Oreochromis niloticus	60.89	0.00e+00	1171.00
IUUC-Oan-072709	Ornithorhynchus anatinus	76.86	0.00e+00	1192.00
IUUC-Ocu-074832	Oryctolagus cuniculus	89.68	0.00e+00	1811.00
IUUC-Ola-087003	Oryzias latipes	65.93	3.00e-41	161.00
IUUC-Oar-089472	Ovis aries	83.93	0.00e+00	1704.00
IUUC-Ptr-090996	Pan troglodytes	89.59	0.00e+00	1806.00
IUUC-Pan-091837	Papio anubis	89.70	0.00e+00	1811.00
IUUC-Psi-093236	Pelodiscus sinensis	72.13	0.00e+00	1108.00
IUUC-Pma-094349	Petromyzon marinus	51.35	0.00e+00	914.00
IUUC-Pfo-097193	Poecilia formosa	60.92	0.00e+00	1137.00
IUUC-Pab-098710	Pongo abelii	89.58	0.00e+00	1832.00
IUUC-Pca-100794	Procavia capensis	77.96	0.00e+00	1519.00
IUUC-Pva-102722	Pteropus vampyrus	89.04	0.00e+00	1766.00
IUUC-Rno-105743	Rattus norvegicus	84.62	0.00e+00	1702.00
IUUC-Sha-106563	Sarcophilus harrisii	81.10	0.00e+00	1339.00
IUUC-Sar-113533	Sorex araneus	73.76	0.00e+00	1443.00
IUUC-Ssc-116259	Sus scrofa	79.27	0.00e+00	1537.00
IUUC-Tgu-117475	Taeniopygia guttata	71.76	0.00e+00	1269.00
IUUC-Tru-118623	Takifugu rubripes	63.29	0.00e+00	985.00
IUUC-Tsy-119250	Tarsius syrichta	87.61	0.00e+00	1367.00
IUUC-Tni-120441	Tetraodon nigroviridis	56.87	0.00e+00	1043.00
IUUC-Tbe-127936	Tupaia belangeri	76.22	0.00e+00	1454.00
IUUC-Ttr-128483	Tursiops truncatus	75.87	0.00e+00	1339.00
IUUC-Vpa-130303	Vicugna pacos	97.03	0.00e+00	1059.00
IUUC-Xtr-132773	Xenopus tropicalis	70.88	0.00e+00	1354.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence