iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gac-041431

UUCD1 version

UUC-GaA-00696

Ensembl Protein ID

ENSGACP00000018020.1

UniProt Accession

G3PK90; G3PK90_GASAC

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000013626.1	ENSGACT00000018055.1	ENSGACP00000018020.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/APC_C/CDC20	8.10e-133	442.8	172	479
E3 adaptor/Cullin RING/DCX/DWD	1.90e-29	100.8	307	342

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkk 88
           p+++ldapelr+dfylnLldWss+nvlavaL++svyl +a++gdv+ l+ l +e+d+v+s+sw++egt+la+Gt++ +++++Dv ++k+
   Q: 172  PDRILDAPELRNDFYLNLLDWSSRNVLAVALHNSVYLLDATQGDVTFLMSLeREEDYVCSLSWTKEGTYLAIGTSDCKIQLWDVYNQKR 260
           689************************************************8899********************************** PP
   S: 89   vrtltghsarvgaLsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdassse....Plk 173
           +r++++h++rv +LsWn++vlssGsr+g+i+h+dvrv+++++ tl++h+qevCGl+w+ d+++LasGGnDn+v vw   ++      ++
   Q: 261  LRSMSSHTSRVVSLSWNDHVLSSGSRSGHIHHHDVRVADHHIFTLTGHSQEVCGLQWSPDGRYLASGGNDNMVYVWPRVQEGtasqSVR 349
           ****************************************************************************9877655555889 PP
   S: 174  kfkehkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvae 262
           +++eh++avka+aw+Pwq+++LasGGGt+Dr+i++wn+++g++++++dt+sq++sl++++++kelvs+hG+a+n++++wkyp ls+vae
   Q: 350  SWSEHQGAVKALAWCPWQPNILASGGGTSDRHIRIWNVNSGSCISSLDTQSQISSLVFAPNYKELVSAHGYAHNNVVIWKYPALSRVAE 438
           999************************************************************************************** PP
   S: 263  lkgheaRvlslalspdgeaivtaagDetlrfwklfdkkkak 303
           l+ghe Rvlsl lspd ++++t+agDet+r+wk f+++++k
   Q: 439  LNGHEDRVLSLILSPDCSTVATVAGDETIRLWKSFEMDPVK 479
           ************************************99876 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvW.Dlrtg 33
           gH+ +v++l++ +d ++l+sG++D+ ++vW ++ +g
   Q: 307  GHSQEVCGLQWsPDgRYLASGGNDNMVYVWpRVQEG 342
           8***********999***************666655 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

MAQFGFENDI HSILKLDMPI TNAPMARWQR KASSSNAAAL SGLSPGKSAN ASLGSSKTPS 60
KTPGKNKKVT PSKMGGDRFI PTRNSKQMDV ASFLLSKENE PVDANNSTST AESQKAWSMS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTCGAACGA GAGTTTTCCA CGTTTTCCCA AAGAGGTGAG ATGATTGGGT TTATTACGAG 60
GTTGTGTGAA AGTCCCACTT TAGACTTCAC ATTAACTTTT GACGAAATTA ATGAATGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033187--CDC20
IPR033010--Cdc20/Fizzy
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000974	Aegilops tauschii	42.55	9.00e-97	347.00
IUUC-Aml-001545	Ailuropoda melanoleuca	61.63	4.00e-177	614.00
IUUC-Apl-003255	Anas platyrhynchos	61.19	8.00e-168	583.00
IUUC-Aca-004920	Anolis carolinensis	59.02	3.00e-172	597.00
IUUC-Aly-006303	Arabidopsis lyrata	44.55	1.00e-99	357.00
IUUC-Ath-006795	Arabidopsis thaliana	43.10	3.00e-100	358.00
IUUC-Ame-010850	Astyanax mexicanus	71.48	3.00e-109	387.00
IUUC-Bgr-012059	Blumeria graminis	46.33	3.00e-88	319.00
IUUC-Bta-012625	Bos taurus	61.63	4.00e-177	614.00
IUUC-Bci-013607	Botrytis cinerea	45.00	6.00e-89	321.00
IUUC-Bdi-014344	Brachypodium distachyon	43.54	8.00e-97	347.00
IUUC-Bol-015851	Brassica oleracea	43.60	4.00e-100	358.00
IUUC-Bra-016738	Brassica rapa	43.63	1.00e-99	357.00
IUUC-Cja-019132	Callithrix jacchus	61.43	2.00e-177	615.00
IUUC-Cfa-020780	Canis familiaris	61.23	2.00e-176	612.00
IUUC-Cpo-022223	Cavia porcellus	62.62	4.00e-166	577.00
IUUC-Cre-022701	Chlamydomonas reinhardtii	45.52	3.00e-106	378.00
IUUC-Csa-023666	Chlorocebus sabaeus	61.63	4.00e-177	613.00
IUUC-Cho-024920	Choloepus hoffmanni	61.19	4.00e-96	345.00
IUUC-Cin-025675	Ciona intestinalis	48.52	1.00e-121	430.00
IUUC-Csv-026019	Ciona savignyi	48.01	2.00e-117	416.00
IUUC-Cgl-026465	Colletotrichum gloeosporioides	44.48	2.00e-88	320.00
IUUC-Cne-026872	Cryptococcus neoformans	45.96	1.00e-85	310.00
IUUC-Cme-027234	Cyanidioschyzon merolae	45.65	3.00e-96	345.00
IUUC-Dre-028026	Danio rerio	70.80	0.00e+00	728.00
IUUC-Dno-028865	Dasypus novemcinctus	59.33	1.00e-173	602.00
IUUC-Dor-030958	Dipodomys ordii	61.75	6.00e-176	610.00
IUUC-Dme-031905	Drosophila melanogaster	44.63	4.00e-122	431.00
IUUC-Ete-032387	Echinops telfairi	56.46	3.00e-164	571.00
IUUC-Eca-033522	Equus caballus	54.40	4.00e-152	531.00
IUUC-Eeu-035059	Erinaceus europaeus	54.29	4.00e-149	521.00
IUUC-Fca-036346	Felis catus	63.37	9.00e-162	563.00
IUUC-Fal-037558	Ficedula albicollis	58.81	9.00e-174	603.00
IUUC-Fox-037850	Fusarium oxysporum	44.48	5.00e-89	322.00
IUUC-Fso-038375	Fusarium solani	44.75	4.00e-89	322.00
IUUC-Gmo-039284	Gadus morhua	81.04	0.00e+00	805.00
IUUC-Ggr-039864	Gaeumannomyces graminis	43.41	1.00e-89	323.00
IUUC-Gga-040790	Gallus gallus	61.40	4.00e-180	624.00
IUUC-Gma-043489	Glycine max	42.66	5.00e-99	354.00
IUUC-Ggo-045052	Gorilla gorilla	61.43	7.00e-177	613.00
IUUC-Hsa-046305	Homo sapiens	61.43	7.00e-177	613.00
IUUC-Hvu-047476	Hordeum vulgare	42.82	2.00e-98	352.00
IUUC-Itr-048461	Ictidomys tridecemlineatus	62.82	4.00e-167	581.00
IUUC-Lch-050174	Latimeria chalumnae	57.09	5.00e-149	520.00
IUUC-Lpe-050954	Leersia perrieri	43.28	5.00e-88	318.00
IUUC-Loc-052638	Lepisosteus oculatus	69.09	0.00e+00	664.00
IUUC-Lma-052998	Leptosphaeria maculans	42.59	1.00e-85	310.00
IUUC-Laf-053742	Loxodonta africana	60.83	3.00e-174	604.00
IUUC-Mcc-054948	Macaca mulatta	61.63	4.00e-177	613.00
IUUC-Meu-056013	Macropus eugenii	60.63	7.00e-95	340.00
IUUC-Mor-057277	Magnaporthe oryzae	44.48	9.00e-87	314.00
IUUC-Mpo-057624	Magnaporthe poae	43.21	5.00e-87	315.00
IUUC-Mtr-057725	Medicago truncatula	43.12	8.00e-91	327.00
IUUC-Mga-060102	Meleagris gallopavo	61.70	4.00e-180	624.00
IUUC-Mmr-061615	Microcebus murinus	62.76	1.00e-177	615.00
IUUC-Mdo-061982	Monodelphis domestica	62.81	4.00e-155	542.00
IUUC-Mmu-063864	Mus musculus	62.43	2.00e-176	612.00
IUUC-Mac-064861	Musa acuminata	42.45	2.00e-97	349.00
IUUC-Mpu-066502	Mustela putorius furo	60.44	5.00e-178	617.00
IUUC-Mlu-067277	Myotis lucifugus	58.89	1.00e-164	573.00
IUUC-Ncr-068951	Neurospora crassa	45.45	4.00e-87	315.00
IUUC-Nle-070149	Nomascus leucogenys	61.63	2.00e-175	608.00
IUUC-Opr-070778	Ochotona princeps	62.26	4.00e-123	434.00
IUUC-Ont-071660	Oreochromis niloticus	87.05	0.00e+00	821.00
IUUC-Oan-073677	Ornithorhynchus anatinus	54.65	8.00e-143	500.00
IUUC-Ocu-073797	Oryctolagus cuniculus	62.08	3.00e-176	612.00
IUUC-Oba-075946	Oryza barthii	44.88	5.00e-97	348.00
IUUC-Obr-076018	Oryza brachyantha	44.39	5.00e-97	348.00
IUUC-Ogl-077254	Oryza glaberrima	43.03	2.00e-88	319.00
IUUC-Ogu-078521	Oryza glumaepatula	45.07	7.00e-97	348.00
IUUC-Oin-079145	Oryza indica	44.88	5.00e-97	348.00
IUUC-Olo-080798	Oryza longistaminata	45.32	8.00e-97	348.00
IUUC-Ome-081186	Oryza meridionalis	45.12	3.00e-97	350.00
IUUC-Oni-082540	Oryza nivara	44.88	1.00e-96	347.00
IUUC-Opu-083901	Oryza punctata	44.88	3.00e-96	345.00
IUUC-Oru-084562	Oryza rufipogon	45.07	1.00e-96	347.00
IUUC-Osa-086094	Oryza sativa	42.79	5.00e-88	318.00
IUUC-Ola-086907	Oryzias latipes	83.07	0.00e+00	765.00
IUUC-Olu-087647	Ostreococcus lucimarinus	43.06	6.00e-101	360.00
IUUC-Oga-088184	Otolemur garnettii	60.71	1.00e-172	599.00
IUUC-Oar-090023	Ovis aries	59.88	3.00e-162	564.00
IUUC-Ptr-090935	Pan troglodytes	60.38	6.00e-163	566.00
IUUC-Pan-091845	Papio anubis	61.63	4.00e-177	613.00
IUUC-Psi-093188	Pelodiscus sinensis	61.28	0.00e+00	645.00
IUUC-Pma-094187	Petromyzon marinus	51.01	6.00e-133	467.00
IUUC-Pno-094809	Phaeosphaeria nodorum	38.26	9.00e-87	314.00
IUUC-Ppa-095457	Physcomitrella patens	44.01	5.00e-99	354.00
IUUC-Pfo-097429	Poecilia formosa	78.29	0.00e+00	712.00
IUUC-Pab-098603	Pongo abelii	61.63	4.00e-177	614.00
IUUC-Pop-099654	Populus trichocarpa	44.39	1.00e-97	350.00
IUUC-Pca-101062	Procavia capensis	61.16	3.00e-174	604.00
IUUC-Ppe-101865	Prunus persica	43.22	3.00e-89	322.00
IUUC-Pva-102925	Pteropus vampyrus	60.83	3.00e-176	611.00
IUUC-Pte-104142	Pyrenophora teres	43.70	3.00e-85	309.00
IUUC-Pyt-104693	Pyrenophora triticirepentis	43.99	1.00e-85	310.00
IUUC-Rno-106005	Rattus norvegicus	62.62	1.00e-175	608.00
IUUC-Sha-107472	Sarcophilus harrisii	60.91	6.00e-175	607.00
IUUC-Sja-107919	Schizosaccharomyces japonicus	38.50	1.00e-84	307.00
IUUC-Spo-108075	Schizosaccharomyces pombe	41.77	6.00e-91	327.00
IUUC-Ssl-108507	Sclerotinia sclerotiorum	46.04	4.00e-89	322.00
IUUC-Smo-108922	Selaginella moellendorffii	43.27	4.00e-105	375.00
IUUC-Sit-110732	Setaria italica	42.79	3.00e-95	342.00
IUUC-Sly-111025	Solanum lycopersicum	43.34	5.00e-89	321.00
IUUC-Stu-112676	Solanum tuberosum	43.34	1.00e-90	326.00
IUUC-Sar-113092	Sorex araneus	58.96	2.00e-159	555.00
IUUC-Sbi-114558	Sorghum bicolor	42.30	5.00e-95	341.00
IUUC-Ssc-115710	Sus scrofa	61.63	2.00e-176	612.00
IUUC-Tgu-117100	Taeniopygia guttata	58.61	1.00e-173	603.00
IUUC-Tru-118184	Takifugu rubripes	73.19	2.00e-178	618.00
IUUC-Tsy-118892	Tarsius syrichta	61.54	5.00e-98	350.00
IUUC-Tni-120474	Tetraodon nigroviridis	82.67	0.00e+00	762.00
IUUC-Tca-120949	Theobroma cacao	42.96	2.00e-97	349.00
IUUC-Tre-122211	Trichoderma reesei	37.96	7.00e-89	320.00
IUUC-Tvi-122531	Trichoderma virens	44.41	2.00e-88	319.00
IUUC-Tae-124946	Triticum aestivum	43.63	2.00e-93	335.00
IUUC-Tur-126018	Triticum urartu	43.63	2.00e-93	335.00
IUUC-Tbe-127384	Tupaia belangeri	66.22	2.00e-121	428.00
IUUC-Ttr-128511	Tursiops truncatus	61.83	5.00e-177	613.00
IUUC-Vda-129993	Verticillium dahliae	40.04	6.00e-92	331.00
IUUC-Vpa-130775	Vicugna pacos	44.48	1.00e-70	260.00
IUUC-Vvi-131245	Vitis vinifera	42.59	1.00e-86	313.00
IUUC-Xtr-131993	Xenopus tropicalis	61.00	0.00e+00	639.00
IUUC-Xma-133332	Xiphophorus maculatus	81.47	0.00e+00	786.00
IUUC-Zma-135135	Zea mays	42.30	8.00e-95	340.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence