iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-001964

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01004208

Gene Name

USP12

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000001863.1	ENSAMET00000002060.1	ENSAMEP00000001981.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.70e-98	328.9	39	368

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgy 87
           +Gl N+gNtCY+NSvLQ+L++++++re +l  +k++      + +k++ll++l++lf+++   k+k +++ p+++++ l+ke+e f++y
   Q: 39   FGLVNFGNTCYCNSVLQALYFCRPFREKVLA-YKSQ------PRKKENLLTCLADLFHSIAtqKKKVGVIPPKKFITRLRKENELFDNY 120
           6******************************.4444......456789************976777779******************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpv 176
           +qqDa+Efl++ll+++ + l++   ++k+e+++ +  + + ++e+++ +  +++++++Fqg+l+++++cl+c+++ss++e+fldls++v
   Q: 121  MQQDAHEFLNYLLNTIADILQE---ERKQEKQNGRLPNGNIDSENNNSTPDPTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDV 206
           ********************44...333344344444444556777888888************************************* PP
   S: 177  pgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfc 265
           ++++     s+++cL+ f+++e+l++e kyyce+c++kqea k++k+kklP +L lhLkRf++  + ++ +k++ +v fpleL l  f+
   Q: 207  EQNT-----SITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRL--FN 288
           ****.....9**********************************************************************66665..77 PP
   S: 266  tspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetg.........staYvlfYkr 337
           ts +   + ++ Y+L+avvvH G +++ GHY+a+vk+ ++ WllfdD+ V++++ + ++e+ g         +++Y+lfY++
   Q: 289  TSGDA-TNPDRMYDLVAVVVHCGsGPNRGHYIAIVKS-HDFWLLFDDDIVEKIDAQAIEEFYGltsdisknsESGYILFYQS 368
           77444.4469***************************.555*******************999*****************97 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MSVLLTVSRG QPICHVGANA SALEKEIGPE QFPVNEHYFG LVNFGNTCYC NSVLQALYFC 60
RPFREKVLAY KSQPRKKENL LTCLADLFHS IATQKKKVGV IPPKKFITRL RKENELFDNY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCAGTTT TATGTATGTG GTGGTACGTT TTCTTGGGAA TTTTCAAGTA ACCGTATCTA 60
GAGTTATGTT TTCAGAGTTG CTGTCATTTG CCTTTTCAGC TGTGTTTGGA GTCCATTTAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003411	Anas platyrhynchos	95.68	0.00e+00	737.00
IUUC-Aca-005212	Anolis carolinensis	96.22	0.00e+00	748.00
IUUC-Acl-008239	Aspergillus clavatus	49.00	9.00e-78	285.00
IUUC-Afl-008602	Aspergillus flavus	50.17	5.00e-80	292.00
IUUC-Afu-008816	Aspergillus fumigatus	50.17	4.00e-78	286.00
IUUC-Ani-009137	Aspergillus nidulans	48.82	1.00e-75	278.00
IUUC-Ang-009703	Aspergillus niger	49.49	3.00e-80	293.00
IUUC-Aor-009901	Aspergillus oryzae	50.17	4.00e-80	292.00
IUUC-Ate-010431	Aspergillus terreus	50.17	4.00e-78	286.00
IUUC-Ame-011015	Astyanax mexicanus	90.84	0.00e+00	714.00
IUUC-Bgr-012071	Blumeria graminis	43.71	3.00e-75	276.00
IUUC-Bta-012981	Bos taurus	97.03	0.00e+00	751.00
IUUC-Bci-013837	Botrytis cinerea	40.87	2.00e-73	270.00
IUUC-Cja-018831	Callithrix jacchus	97.03	0.00e+00	756.00
IUUC-Cfa-020534	Canis familiaris	97.30	0.00e+00	758.00
IUUC-Cpo-021703	Cavia porcellus	99.44	0.00e+00	739.00
IUUC-Cho-024902	Choloepus hoffmanni	83.33	7.00e-173	599.00
IUUC-Cin-025659	Ciona intestinalis	56.60	3.00e-130	458.00
IUUC-Csv-025828	Ciona savignyi	53.30	1.00e-122	432.00
IUUC-Cgl-026611	Colletotrichum gloeosporioides	43.23	6.00e-75	275.00
IUUC-Dre-027845	Danio rerio	91.37	0.00e+00	718.00
IUUC-Dno-029460	Dasypus novemcinctus	99.72	0.00e+00	741.00
IUUC-Dor-030972	Dipodomys ordii	100.00	4.00e-154	536.00
IUUC-Dse-031470	Dothistroma septosporum	48.54	4.00e-77	282.00
IUUC-Ete-033125	Echinops telfairi	78.23	1.00e-132	465.00
IUUC-Eca-033439	Equus caballus	100.00	0.00e+00	742.00
IUUC-Fca-035524	Felis catus	99.15	0.00e+00	738.00
IUUC-Fal-036833	Ficedula albicollis	97.76	0.00e+00	731.00
IUUC-Gmo-038763	Gadus morhua	90.86	0.00e+00	717.00
IUUC-Gga-041151	Gallus gallus	96.49	0.00e+00	746.00
IUUC-Gac-041967	Gasterosteus aculeatus	91.40	0.00e+00	720.00
IUUC-Hsa-045700	Homo sapiens	97.03	0.00e+00	756.00
IUUC-Itr-049082	Ictidomys tridecemlineatus	99.72	0.00e+00	743.00
IUUC-Lch-050435	Latimeria chalumnae	98.03	0.00e+00	712.00
IUUC-Loc-051968	Lepisosteus oculatus	93.78	0.00e+00	738.00
IUUC-Lma-053300	Leptosphaeria maculans	47.25	9.00e-79	288.00
IUUC-Laf-053887	Loxodonta africana	97.57	0.00e+00	759.00
IUUC-Mcc-055701	Macaca mulatta	97.03	0.00e+00	755.00
IUUC-Mor-057072	Magnaporthe oryzae	43.97	5.00e-76	278.00
IUUC-Mpo-057424	Magnaporthe poae	43.48	4.00e-75	276.00
IUUC-Mga-059195	Meleagris gallopavo	96.20	0.00e+00	735.00
IUUC-Mmr-060751	Microcebus murinus	97.57	0.00e+00	759.00
IUUC-Mdo-062735	Monodelphis domestica	95.43	0.00e+00	741.00
IUUC-Mmu-063263	Mus musculus	95.95	0.00e+00	748.00
IUUC-Mlu-068128	Myotis lucifugus	100.00	0.00e+00	742.00
IUUC-Nfi-068611	Neosartorya fischeri	50.17	4.00e-78	286.00
IUUC-Ncr-068699	Neurospora crassa	44.95	3.00e-75	276.00
IUUC-Nle-069767	Nomascus leucogenys	99.15	0.00e+00	739.00
IUUC-Opr-070582	Ochotona princeps	92.09	0.00e+00	671.00
IUUC-Ont-072658	Oreochromis niloticus	91.67	0.00e+00	722.00
IUUC-Oan-073372	Ornithorhynchus anatinus	98.59	0.00e+00	734.00
IUUC-Ocu-074322	Oryctolagus cuniculus	96.49	0.00e+00	744.00
IUUC-Ola-087418	Oryzias latipes	91.67	0.00e+00	722.00
IUUC-Oga-088298	Otolemur garnettii	100.00	0.00e+00	742.00
IUUC-Oar-090269	Ovis aries	98.60	0.00e+00	734.00
IUUC-Ptr-090467	Pan troglodytes	97.03	0.00e+00	756.00
IUUC-Pan-092437	Papio anubis	96.99	0.00e+00	738.00
IUUC-Psi-092993	Pelodiscus sinensis	99.15	0.00e+00	738.00
IUUC-Pma-094388	Petromyzon marinus	86.63	0.00e+00	674.00
IUUC-Pno-095044	Phaeosphaeria nodorum	48.18	2.00e-78	287.00
IUUC-Pfo-097052	Poecilia formosa	91.67	0.00e+00	722.00
IUUC-Pab-097797	Pongo abelii	97.03	0.00e+00	756.00
IUUC-Pca-100835	Procavia capensis	90.52	4.00e-174	603.00
IUUC-Pgr-103306	Puccinia graminis	53.97	2.00e-95	344.00
IUUC-Pte-104356	Pyrenophora teres	47.56	7.00e-78	285.00
IUUC-Pyt-104709	Pyrenophora triticirepentis	47.88	2.00e-78	286.00
IUUC-Rno-106060	Rattus norvegicus	98.31	0.00e+00	732.00
IUUC-Sce-106196	Saccharomyces cerevisiae	38.38	5.00e-56	212.00
IUUC-Sha-107087	Sarcophilus harrisii	97.57	0.00e+00	759.00
IUUC-Sja-107684	Schizosaccharomyces japonicus	45.92	8.00e-68	251.00
IUUC-Spo-108095	Schizosaccharomyces pombe	46.74	2.00e-76	280.00
IUUC-Sar-113216	Sorex araneus	99.15	0.00e+00	733.00
IUUC-Sre-115197	Sporisorium reilianum	50.18	3.00e-80	293.00
IUUC-Ssc-116321	Sus scrofa	95.16	0.00e+00	738.00
IUUC-Tgu-117482	Taeniopygia guttata	96.08	0.00e+00	705.00
IUUC-Tru-118613	Takifugu rubripes	91.67	0.00e+00	721.00
IUUC-Tsy-119520	Tarsius syrichta	89.02	1.00e-132	465.00
IUUC-Tni-120293	Tetraodon nigroviridis	91.67	0.00e+00	721.00
IUUC-Tre-122226	Trichoderma reesei	45.03	3.00e-76	279.00
IUUC-Tvi-122330	Trichoderma virens	46.69	1.00e-75	278.00
IUUC-Tme-126890	Tuber melanosporum	46.67	1.00e-90	327.00
IUUC-Tbe-127783	Tupaia belangeri	98.87	0.00e+00	723.00
IUUC-Ttr-129083	Tursiops truncatus	97.30	0.00e+00	758.00
IUUC-Vda-129736	Verticillium dahliae	39.09	2.00e-58	220.00
IUUC-Vpa-130391	Vicugna pacos	94.92	0.00e+00	692.00
IUUC-Xtr-132464	Xenopus tropicalis	99.15	0.00e+00	713.00
IUUC-Xma-133475	Xiphophorus maculatus	91.67	0.00e+00	722.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence