iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-004006

Ensembl Protein ID

ENSAPLP00000007153.1

UniProt Accession

U3IIT1; U3IIT1_ANAPL

Genbank Protein ID

ENSAPLP00000007153

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01007523

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000007508.1	ENSAPLT00000007808.1	ENSAPLP00000007153.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.40e-60	205.0	5	321

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +Gl N+g tC +NS+LQ+ ++   ++  l +    +++ ++ + +  ++  ++  l+e+++++k+kav p++l ++l+     ++ ++q
   Q: 5    VGLYNMGHTCCLNSLLQVFLMNIHFTGILRR---ITVPPNA-SLKRRNVPYQMLLLLEKMQSGKQKAVFPTDLARCLSVHR--MDLFMQ 87
           6*************************99999...3333322.3455689****************************9544..579*** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +Da  +   l + ++ ++                          k++   + +sdl+ + +++++ c+ c ++++r++++l+l+lpv +
   Q: 88   HDAAQLYLTLWNLVKMQI--------------------------KDQDLVTKLSDLYTICVQEHLACQICSSETKRNSNMLTLPLPVLD 150
           ******************..........................56778899************************************* PP
   S: 179  keetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts 267
           +++ k+++l+dcL+ f+ +eel+g+n+++ce c+kk+   +++kl +lP++L++hLkRf+f+++  s +k++ ++ fp+eLd + ++t+
   Q: 151  SNSHKLKTLEDCLQCFFHPEELTGHNMCFCEYCEKKTPFLQSMKLVHLPQTLTIHLKRFCFERS-ASVHKLSHCLPFPEELDFNAVLTE 238
           *************************************************************887.6667****************9999 PP
   S: 268  peekqke....kkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetg.......staYvlfYkrr 338
           ++++ ++      +YeL+avv HsGs++ GHY+ay+++ ++ kW++f+Ds+V +v++++v+ + g       +taY+l+Y+++
   Q: 239  QQSQAHDsekaAWQYELFAVVTHSGSANFGHYCAYIRSlTECKWYCFNDSTVDQVSWDDVKCTYGhsdlywgQTAYLLIYMKK 321
           77666556666899************************56666*******************888***************985 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

PTGAVGLYNM GHTCCLNSLL QVFLMNIHFT GILRRITVPP NASLKRRNVP YQMLLLLEKM 60
QSGKQKAVFP TDLARCLSVH RMDLFMQHDA AQLYLTLWNL VKMQIKDQDL VTKLSDLYTI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTACAGGAG CTGTTGGACT TTACAACATG GGGCACACCT GCTGTCTGAA CTCTCTACTC 60
CAAGTGTTCC TCATGAACAT ACACTTCACT GGGATACTAC GAAGGTACCA CCTGTTTGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0019785--F:ISG15-specific protease activity
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0035634--P:response to stilbenoid
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001615	Ailuropoda melanoleuca	56.96	1.00e-102	365.00
IUUC-Aca-005088	Anolis carolinensis	56.39	9.00e-95	339.00
IUUC-Ame-010606	Astyanax mexicanus	37.34	3.00e-48	185.00
IUUC-Bta-013036	Bos taurus	54.72	5.00e-101	360.00
IUUC-Cja-019052	Callithrix jacchus	52.96	1.00e-90	325.00
IUUC-Cfa-020554	Canis familiaris	56.88	1.00e-106	379.00
IUUC-Cpo-022421	Cavia porcellus	57.01	8.00e-102	363.00
IUUC-Csa-023737	Chlorocebus sabaeus	53.23	3.00e-59	220.00
IUUC-Cho-024807	Choloepus hoffmanni	49.48	3.00e-43	168.00
IUUC-Dre-027408	Danio rerio	36.08	2.00e-47	182.00
IUUC-Dno-029813	Dasypus novemcinctus	47.80	8.00e-75	273.00
IUUC-Dor-030532	Dipodomys ordii	56.07	3.00e-102	364.00
IUUC-Ete-032254	Echinops telfairi	53.42	3.00e-99	354.00
IUUC-Eca-033482	Equus caballus	56.92	3.00e-106	377.00
IUUC-Eeu-034451	Erinaceus europaeus	50.00	1.00e-56	212.00
IUUC-Fca-036313	Felis catus	56.88	2.00e-106	378.00
IUUC-Fal-037216	Ficedula albicollis	76.25	5.00e-144	503.00
IUUC-Gmo-038649	Gadus morhua	33.86	5.00e-49	187.00
IUUC-Gga-041082	Gallus gallus	79.38	2.00e-146	511.00
IUUC-Gac-042439	Gasterosteus aculeatus	37.66	4.00e-51	194.00
IUUC-Ggo-044957	Gorilla gorilla	54.04	1.00e-82	298.00
IUUC-Hsa-046381	Homo sapiens	56.88	1.00e-105	375.00
IUUC-Itr-047918	Ictidomys tridecemlineatus	55.94	2.00e-103	368.00
IUUC-Loc-052688	Lepisosteus oculatus	36.76	9.00e-52	196.00
IUUC-Laf-054109	Loxodonta africana	56.56	3.00e-106	377.00
IUUC-Mcc-054814	Macaca mulatta	56.88	2.00e-105	375.00
IUUC-Meu-056253	Macropus eugenii	52.10	1.00e-77	282.00
IUUC-Mmr-061613	Microcebus murinus	56.56	4.00e-103	367.00
IUUC-Mdo-061890	Monodelphis domestica	54.23	4.00e-94	337.00
IUUC-Mmu-064329	Mus musculus	55.31	2.00e-97	348.00
IUUC-Mpu-066342	Mustela putorius furo	57.50	3.00e-108	384.00
IUUC-Mlu-067010	Myotis lucifugus	55.00	5.00e-102	363.00
IUUC-Nle-069148	Nomascus leucogenys	56.88	1.00e-105	375.00
IUUC-Opr-070988	Ochotona princeps	50.96	2.00e-43	169.00
IUUC-Ont-072039	Oreochromis niloticus	36.48	3.00e-49	188.00
IUUC-Oan-073740	Ornithorhynchus anatinus	48.04	2.00e-57	214.00
IUUC-Ocu-074498	Oryctolagus cuniculus	55.97	1.00e-95	342.00
IUUC-Ola-086753	Oryzias latipes	38.29	2.00e-51	195.00
IUUC-Oga-088497	Otolemur garnettii	55.99	1.00e-100	359.00
IUUC-Oar-089505	Ovis aries	54.72	1.00e-99	355.00
IUUC-Ptr-091656	Pan troglodytes	57.19	5.00e-107	380.00
IUUC-Pan-092498	Papio anubis	56.88	1.00e-105	375.00
IUUC-Psi-093409	Pelodiscus sinensis	62.54	9.00e-124	436.00
IUUC-Pfo-096507	Poecilia formosa	36.83	3.00e-50	191.00
IUUC-Pab-097828	Pongo abelii	55.45	3.00e-101	361.00
IUUC-Pca-100299	Procavia capensis	58.82	2.00e-61	229.00
IUUC-Pva-102972	Pteropus vampyrus	54.06	5.00e-100	357.00
IUUC-Rno-105738	Rattus norvegicus	54.83	2.00e-100	358.00
IUUC-Sha-107309	Sarcophilus harrisii	50.98	2.00e-86	312.00
IUUC-Sar-112983	Sorex araneus	52.98	6.00e-80	290.00
IUUC-Ssc-116049	Sus scrofa	55.21	1.00e-102	365.00
IUUC-Tgu-117115	Taeniopygia guttata	76.09	4.00e-146	510.00
IUUC-Tru-118022	Takifugu rubripes	35.42	4.00e-44	171.00
IUUC-Tsy-118986	Tarsius syrichta	58.87	1.00e-35	143.00
IUUC-Tni-120306	Tetraodon nigroviridis	36.51	4.00e-43	167.00
IUUC-Tbe-127768	Tupaia belangeri	50.85	7.00e-60	223.00
IUUC-Ttr-128686	Tursiops truncatus	56.25	2.00e-104	371.00
IUUC-Xtr-132032	Xenopus tropicalis	42.95	2.00e-71	262.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence