iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ocu-073824

Ensembl Protein ID

ENSOCUP00000011973.3

UniProt Accession

G1T6E0; G1T6E0_RABIT

Genbank Protein ID

ENSOCUP00000011973

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02000614

Gene Name

OTUD7B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000013924.3	ENSOCUT00000013923.3	ENSOCUP00000011973.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/OTU	1.20e-37	129.4	184	365

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/OTU

   S: 2    lilktkgDGnCLlrAvsqsllgvfddds.lsdalveaLreltseylqkesdffsefieek...........edekefcqklvepe.... 74
           l+l+t+gDGnCLl+A+s +++g++d+d+ l++al+  + + +++++ k+++++++++++k           ++e++++ kl+++e    
   Q: 184  LPLATTGDGNCLLHAASLGMWGFHDRDLmLRKALYALMEKGIEKEALKRRWRWQQTQQNKesglvytedewQKEWNELIKLASSEprmh 272
           6899********************************************************************************99988 PP
   S: 75   ..akg.................eeihifaLaqiLsrpiivvdvdsles.........kvggillpllfpeek.lkkpivLlYrsgHYda 134
             a g                 ee+h+f+La++L+rpi+vv++++l++         ++ggi+lpl++p+++ +++p+vL+Y+++H++a
   Q: 273  lgANGancggvesseepvyeslEEFHVFVLAHVLRRPIVVVADTMLRDsggeafapiPFGGIYLPLEVPASQcHRSPLVLAYDQAHFSA 361
           8733356689******************************************************************************* PP
   S: 135  Lval 138
           Lv++
   Q: 362  LVSM 365
           *986 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MTLDMDAVLS DFVRSTGAEP GLARDLLEGK NWDVSAALSD FEQLRQVHAG NLLPSFSEGS 60
SGSRSPEKGG SDREAARPPR PILQRQDDII QEKRLSRGIS HASSSIVSLA RSHVSSNGGG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTTCCAGAA CCACCCCACC CCTTTCCGCT CCTTGCCAAA GGGCTGGGGC CAACTAATTC 60
TGCCCCGAAG TCTCAAGAAT CCACCCGGTC CACCCCCTCC CTCCCCCCAG CTCCGGTTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003323--OTU_dom

PROSITE

PS50802--OTU

Pfam

PF02338--OTU

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:1990380--F:Lys48-specific deubiquitinase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0002385--P:mucosal immune response
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0032717--P:negative regulation of interleukin-8 production
GO:1900181--P:negative regulation of protein localization to nucleus
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0035871--P:protein K11-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002119	Ailuropoda melanoleuca	94.49	0.00e+00	1001.00
IUUC-Apl-003567	Anas platyrhynchos	82.46	0.00e+00	838.00
IUUC-Bta-013398	Bos taurus	95.02	0.00e+00	962.00
IUUC-Cel-018468	Caenorhabditis elegans	50.67	6.00e-86	311.00
IUUC-Cja-019965	Callithrix jacchus	95.19	0.00e+00	1037.00
IUUC-Cfa-020191	Canis familiaris	94.50	0.00e+00	974.00
IUUC-Cpo-022232	Cavia porcellus	91.38	0.00e+00	894.00
IUUC-Csa-023593	Chlorocebus sabaeus	95.53	0.00e+00	1039.00
IUUC-Csv-026177	Ciona savignyi	28.87	3.00e-03	35.00
IUUC-Dno-029900	Dasypus novemcinctus	93.99	0.00e+00	966.00
IUUC-Dor-031121	Dipodomys ordii	85.61	0.00e+00	694.00
IUUC-Ete-032473	Echinops telfairi	87.46	0.00e+00	899.00
IUUC-Eca-033946	Equus caballus	94.17	0.00e+00	969.00
IUUC-Eeu-034670	Erinaceus europaeus	92.96	0.00e+00	934.00
IUUC-Fca-035871	Felis catus	94.67	0.00e+00	956.00
IUUC-Fso-038203	Fusarium solani	29.00	4.10e-02	33.50
IUUC-Gmo-039373	Gadus morhua	77.47	0.00e+00	684.00
IUUC-Gac-041806	Gasterosteus aculeatus	78.54	0.00e+00	733.00
IUUC-Ggo-045472	Gorilla gorilla	95.53	0.00e+00	993.00
IUUC-Hsa-046473	Homo sapiens	95.19	0.00e+00	994.00
IUUC-Itr-048841	Ictidomys tridecemlineatus	95.19	0.00e+00	971.00
IUUC-Mcc-055261	Macaca mulatta	95.36	0.00e+00	1039.00
IUUC-Meu-056477	Macropus eugenii	81.99	0.00e+00	754.00
IUUC-Mga-059533	Meleagris gallopavo	82.87	0.00e+00	830.00
IUUC-Mdo-062847	Monodelphis domestica	92.40	0.00e+00	879.00
IUUC-Mmu-064260	Mus musculus	90.07	0.00e+00	904.00
IUUC-Mpu-066876	Mustela putorius furo	87.16	0.00e+00	886.00
IUUC-Mlu-068039	Myotis lucifugus	94.17	0.00e+00	951.00
IUUC-Nle-069260	Nomascus leucogenys	94.85	0.00e+00	984.00
IUUC-Opr-070564	Ochotona princeps	93.42	0.00e+00	803.00
IUUC-Ont-071542	Oreochromis niloticus	80.39	0.00e+00	739.00
IUUC-Opu-083273	Oryza punctata	23.38	2.30e-01	30.40
IUUC-Ola-086490	Oryzias latipes	76.87	0.00e+00	706.00
IUUC-Oga-088124	Otolemur garnettii	94.51	0.00e+00	960.00
IUUC-Oar-090086	Ovis aries	95.02	0.00e+00	967.00
IUUC-Ptr-091622	Pan troglodytes	95.19	0.00e+00	998.00
IUUC-Pan-092724	Papio anubis	95.36	0.00e+00	1037.00
IUUC-Pfo-096563	Poecilia formosa	78.71	0.00e+00	732.00
IUUC-Pab-098667	Pongo abelii	95.02	0.00e+00	984.00
IUUC-Pva-102136	Pteropus vampyrus	93.83	0.00e+00	969.00
IUUC-Rno-105546	Rattus norvegicus	90.91	0.00e+00	919.00
IUUC-Sha-106732	Sarcophilus harrisii	86.13	0.00e+00	758.00
IUUC-Sar-113562	Sorex araneus	81.65	0.00e+00	753.00
IUUC-Ssc-116191	Sus scrofa	95.03	0.00e+00	964.00
IUUC-Tgu-116942	Taeniopygia guttata	80.32	0.00e+00	701.00
IUUC-Tru-117911	Takifugu rubripes	78.11	0.00e+00	727.00
IUUC-Tsy-119343	Tarsius syrichta	88.66	0.00e+00	908.00
IUUC-Tbe-127283	Tupaia belangeri	93.90	0.00e+00	762.00
IUUC-Ttr-128692	Tursiops truncatus	89.00	0.00e+00	845.00
IUUC-Xtr-132888	Xenopus tropicalis	79.04	0.00e+00	750.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence