iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000015765.3	ENSXETT00000034378.3	ENSXETP00000034378.3
ENSXETG00000015765.3	ENSXETT00000056607.2	ENSXETP00000056607.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/OTU	1.90e-36	125.7	173	354

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/OTU

   S: 2    lilktkgDGnCLlrAvsqsllgvfddds.lsdalveaLreltseylqkesdffsefieek...........edekefcqklvepe.... 74
           l+l+t+gDGnCLl+A+s +++g++d+d+ l++ l++ + + +++++ k++++f++++++k           ++e++ + kl+++e    
   Q: 173  LPLATTGDGNCLLHAASLGMWGFHDRDLmLRKSLYTLMEKGAEKEALKRRWRFHQTMQNKesglvyteeewQKEWNDLIKLASSEprmh 261
           6899****************************************************************99999*********9998877 PP
   S: 75   ..akg.................eeihifaLaqiLsrpiivvdvdsles.........kvggillpllfpeek.lkkpivLlYrsgHYda 134
             + g                 ee+h+f+La++L+rp++vv++++l++         ++ggi+lpl++p++k +++p+vL+Y+++H++a
   Q: 262  ygTNGgncggvesseepvyeslEEFHVFVLAHVLKRPVVVVADTMLRDsggeafapiPFGGIYLPLEVPPNKcHCSPLVLAYDQAHFSA 350
           7522367788******************************************************************************* PP
   S: 135  Lval 138
           Lv++
   Q: 351  LVSM 354
           *986 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

WPQDTDTVLS EFVRSTGVEP GLARDLLEGK KWDVGAALND YDQLRQTSAG GLGHSFSEGR 60
NFKPPEVGRS VRPMLQRQDD VVQEKRLSRG ISHASSSIVS LARSHVSSNG SSEHPLETPV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCGAACTGA GCGAGGTCAG AGCAGGGAGA GAGCGGGGAG AGAGCGGGGA GAGGAGGGAT 60
CGCTGTGCAG CCCGGAACCC GCCGGGAGCG CTGTGGGACC CACACGGTGC TGCCTTCTAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003323--OTU_dom
IPR002653--Znf_A20

PROSITE

PS50802--OTU
PS51036--ZF_A20

Pfam

PF02338--OTU
PF01754--zf-A20

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0070530--F:K63-linked polyubiquitin binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0006955--P:immune response
GO:0007219--P:Notch signaling pathway
GO:0071947--P:protein deubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0035871--P:protein K11-linked deubiquitination
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002119	Ailuropoda melanoleuca	62.53	0.00e+00	945.00
IUUC-Apl-003567	Anas platyrhynchos	70.82	0.00e+00	1054.00
IUUC-Bta-013398	Bos taurus	61.43	0.00e+00	926.00
IUUC-Cja-019965	Callithrix jacchus	62.40	0.00e+00	940.00
IUUC-Cfa-020191	Canis familiaris	63.18	0.00e+00	942.00
IUUC-Cpo-022232	Cavia porcellus	63.56	0.00e+00	894.00
IUUC-Dno-029900	Dasypus novemcinctus	62.17	0.00e+00	924.00
IUUC-Ete-032473	Echinops telfairi	63.76	0.00e+00	771.00
IUUC-Eca-033946	Equus caballus	68.90	0.00e+00	801.00
IUUC-Eeu-034670	Erinaceus europaeus	61.18	0.00e+00	906.00
IUUC-Fca-035871	Felis catus	61.90	0.00e+00	908.00
IUUC-Gmo-039373	Gadus morhua	77.04	0.00e+00	674.00
IUUC-Gga-041105	Gallus gallus	70.36	0.00e+00	1093.00
IUUC-Gac-041806	Gasterosteus aculeatus	56.22	0.00e+00	831.00
IUUC-Ggo-045472	Gorilla gorilla	63.28	0.00e+00	959.00
IUUC-Hsa-046473	Homo sapiens	63.28	0.00e+00	967.00
IUUC-Itr-048841	Ictidomys tridecemlineatus	62.93	0.00e+00	938.00
IUUC-Lch-050432	Latimeria chalumnae	66.51	0.00e+00	1025.00
IUUC-Mcc-055261	Macaca mulatta	63.97	0.00e+00	993.00
IUUC-Meu-056477	Macropus eugenii	60.53	0.00e+00	752.00
IUUC-Mga-059533	Meleagris gallopavo	68.47	0.00e+00	1041.00
IUUC-Mdo-062847	Monodelphis domestica	62.35	0.00e+00	922.00
IUUC-Mmu-064260	Mus musculus	62.54	0.00e+00	872.00
IUUC-Mpu-066876	Mustela putorius furo	59.55	0.00e+00	852.00
IUUC-Mlu-068039	Myotis lucifugus	62.17	0.00e+00	960.00
IUUC-Ocu-073824	Oryctolagus cuniculus	76.15	0.00e+00	774.00
IUUC-Ola-086490	Oryzias latipes	57.17	0.00e+00	811.00
IUUC-Oga-088124	Otolemur garnettii	61.87	0.00e+00	921.00
IUUC-Oar-090086	Ovis aries	61.43	0.00e+00	922.00
IUUC-Ptr-091622	Pan troglodytes	70.20	0.00e+00	845.00
IUUC-Pan-092724	Papio anubis	63.88	0.00e+00	984.00
IUUC-Psi-093333	Pelodiscus sinensis	70.32	0.00e+00	1073.00
IUUC-Pab-098667	Pongo abelii	63.48	0.00e+00	958.00
IUUC-Pva-102136	Pteropus vampyrus	62.93	0.00e+00	926.00
IUUC-Rno-105546	Rattus norvegicus	62.38	0.00e+00	890.00
IUUC-Sha-106732	Sarcophilus harrisii	62.24	0.00e+00	852.00
IUUC-Sar-113562	Sorex araneus	54.37	0.00e+00	744.00
IUUC-Ssc-116191	Sus scrofa	62.22	0.00e+00	936.00
IUUC-Tgu-116942	Taeniopygia guttata	77.48	0.00e+00	843.00
IUUC-Tsy-119343	Tarsius syrichta	58.57	0.00e+00	862.00
IUUC-Tbe-127283	Tupaia belangeri	74.89	0.00e+00	643.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence