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Tag Content
UUCD2 ID IUUC-Xtr-132268
UUCD1 version UUC-XeT-00867
Ensembl Protein ID ENSXETP00000037873.3
UniProt Accession Q0D2D2; FBX31_XENTR
Genbank Protein ID AAI21977.1
Protein Name F-box only protein 31
Genbank Nucleotide ID BC121976
Gene Name fbxo31
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSXETG00000017407.3 ENSXETT00000037873.3 ENSXETP00000037873.3
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 adaptor/Cullin RING/SCF/F-box 68.21 0.00e+00 695.00 IUUC-Hsa-046605
E3 adaptor/Cullin RING/SCF/F-box 39.53 2.90e-01 32.00 IUUC-Sce-106220
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Xenopus tropicalis
Functional Description
(View)

Functional Description


     Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in G1 arrest following DNA damage. Specifically recognizes phosphorylated cyclin-D1 (ccnd1), promoting its ubiquitination and degradation by the proteasome, resulting in G1 arrest (By similarity).
 Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in G1 arrest following DNA damage. Specifically recognizes phosphorylated cyclin-D1 (ccnd1), promoting its ubiquitination and degradation by the proteasome, resulting in G1 arrest (By similarity).
Protein Sequence
(Fasta)
MAVCARLCGV GQSGGCRRRQ QRKGAGNGPE LEDEEEEDEV RIEAEVIGGQ AAEAPRRPRS 60
LLHLPPEILV EIFSSLPGTE LPSLAQVCRK FRQILTTDTI WKRRCKQEYG VCENLRKLEV 120
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Protein Fasta Sequence


>IUUC-Xtr-132268|E3,F-box|Xenopus tropicalis
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Nucleotide Sequence
(Fasta)
CGGACTGTCA GTGCCAGCGG GCCCCAGTGT GGGATGGCGG TGTGCGCCAG GTTGTGCGGA 60
GTCGGACAGT CCGGGGGCTG CAGGAGGAGA CAACAGCGGA AGGGAGCCGG AAACGGCCCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Xtr-132268|E3,F-box|Xenopus tropicalis
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0131--Cell cycle
KW-0181--Complete proteome
KW-0227--DNA damage
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
Interpro

IPR001810--F-box_dom
IPR026941--FBXO31
PROSITE

PS50181--FBOX
Pfam

PF12937--F-box-like
SMART

SM00256--FBOX
Gene Ontology

GO:0019005--C:SCF ubiquitin ligase complex
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0006974--P:cellular response to DNA damage stimulus
GO:0031571--P:mitotic G1 DNA damage checkpoint
GO:0016567--P:protein ubiquitination
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
KEGG xtr:779980
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000641 Aegilops tauschii 31.25 2.00e-04 39.70
IUUC-Aml-001283 Ailuropoda melanoleuca 85.58 1.00e-170 592.00
IUUC-Atr-003100 Amborella trichopoda 30.77 2.00e-04 41.20
IUUC-Apl-003209 Anas platyrhynchos 73.15 0.00e+00 669.00
IUUC-Aca-004894 Anolis carolinensis 72.41 0.00e+00 715.00
IUUC-Aly-005512 Arabidopsis lyrata 33.77 3.00e-03 37.00
IUUC-Ath-007284 Arabidopsis thaliana 31.00 3.00e-04 40.40
IUUC-Aor-009996 Aspergillus oryzae 32.53 9.00e-04 39.70
IUUC-Ame-011867 Astyanax mexicanus 62.23 0.00e+00 665.00
IUUC-Bgr-012114 Blumeria graminis 35.71 1.00e-03 38.90
IUUC-Bta-012497 Bos taurus 71.84 0.00e+00 701.00
IUUC-Bdi-014535 Brachypodium distachyon 30.77 2.00e-03 37.40
IUUC-Cja-019896 Callithrix jacchus 66.80 0.00e+00 655.00
IUUC-Cfa-020183 Canis familiaris 67.98 5.00e-176 610.00
IUUC-Cpo-022420 Cavia porcellus 66.49 0.00e+00 692.00
IUUC-Cre-022968 Chlamydomonas reinhardtii 33.80 1.00e-04 41.60
IUUC-Csa-023606 Chlorocebus sabaeus 72.98 0.00e+00 727.00
IUUC-Csv-026017 Ciona savignyi 25.88 2.00e-03 37.00
IUUC-Dre-028579 Danio rerio 58.83 0.00e+00 646.00
IUUC-Dno-030013 Dasypus novemcinctus 83.22 2.00e-149 521.00
IUUC-Dor-030865 Dipodomys ordii 66.26 0.00e+00 647.00
IUUC-Eca-033625 Equus caballus 67.71 6.00e-174 603.00
IUUC-Eeu-034639 Erinaceus europaeus 56.73 1.00e-148 519.00
IUUC-Fca-036551 Felis catus 72.49 0.00e+00 692.00
IUUC-Fal-037031 Ficedula albicollis 68.80 0.00e+00 659.00
IUUC-Gmo-039215 Gadus morhua 66.76 3.00e-133 468.00
IUUC-Gga-040962 Gallus gallus 68.26 0.00e+00 665.00
IUUC-Gac-041683 Gasterosteus aculeatus 63.00 0.00e+00 654.00
IUUC-Ggo-044776 Gorilla gorilla 65.02 0.00e+00 657.00
IUUC-Hsa-046605 Homo sapiens 64.16 0.00e+00 657.00
IUUC-Itr-048607 Ictidomys tridecemlineatus 67.34 6.00e-171 593.00
IUUC-Lch-050047 Latimeria chalumnae 67.03 0.00e+00 729.00
IUUC-Lpe-051286 Leersia perrieri 31.94 3.00e-04 40.00
IUUC-Loc-052230 Lepisosteus oculatus 63.94 2.00e-180 625.00
IUUC-Laf-053797 Loxodonta africana 64.58 0.00e+00 665.00
IUUC-Mcc-055189 Macaca mulatta 67.84 7.00e-138 483.00
IUUC-Meu-055993 Macropus eugenii 58.35 6.00e-132 463.00
IUUC-Mga-059198 Meleagris gallopavo 75.00 0.00e+00 677.00
IUUC-Mvi-060509 Microbotryum violaceum 31.19 5.00e-03 36.60
IUUC-Mmr-061738 Microcebus murinus 66.80 0.00e+00 654.00
IUUC-Mdo-062753 Monodelphis domestica 77.85 2.00e-151 529.00
IUUC-Mmu-063936 Mus musculus 65.46 0.00e+00 658.00
IUUC-Mpu-066236 Mustela putorius furo 69.66 8.00e-177 612.00
IUUC-Mlu-068199 Myotis lucifugus 66.31 0.00e+00 679.00
IUUC-Nle-069835 Nomascus leucogenys 66.45 3.00e-169 587.00
IUUC-Opr-071142 Ochotona princeps 69.18 0.00e+00 644.00
IUUC-Ont-071669 Oreochromis niloticus 59.67 0.00e+00 655.00
IUUC-Oan-072716 Ornithorhynchus anatinus 67.97 3.00e-176 610.00
IUUC-Ocu-074345 Oryctolagus cuniculus 65.80 2.00e-174 604.00
IUUC-Oba-075322 Oryza barthii 30.56 6.00e-04 38.90
IUUC-Obr-076323 Oryza brachyantha 30.56 6.00e-04 37.70
IUUC-Ogu-078551 Oryza glumaepatula 30.56 6.00e-04 39.30
IUUC-Oin-079844 Oryza indica 35.62 6.00e-04 38.90
IUUC-Olo-080388 Oryza longistaminata 30.56 3.00e-04 38.90
IUUC-Ome-081606 Oryza meridionalis 30.56 8.00e-04 38.50
IUUC-Oni-082615 Oryza nivara 35.62 7.00e-04 38.90
IUUC-Opu-083870 Oryza punctata 30.56 4.00e-04 39.70
IUUC-Osa-086248 Oryza sativa 35.62 8.00e-04 38.50
IUUC-Ola-087311 Oryzias latipes 68.86 2.00e-163 568.00
IUUC-Oga-089001 Otolemur garnettii 72.21 0.00e+00 734.00
IUUC-Oar-089350 Ovis aries 72.83 0.00e+00 662.00
IUUC-Ptr-090976 Pan troglodytes 67.20 0.00e+00 650.00
IUUC-Pan-092129 Papio anubis 67.94 0.00e+00 653.00
IUUC-Psi-093747 Pelodiscus sinensis 70.18 7.00e-125 439.00
IUUC-Pma-094219 Petromyzon marinus 72.51 7.00e-101 360.00
IUUC-Pfo-096548 Poecilia formosa 64.24 4.00e-179 620.00
IUUC-Pab-098720 Pongo abelii 67.94 0.00e+00 662.00
IUUC-Pop-099194 Populus trichocarpa 30.61 1.00e-03 38.50
IUUC-Pca-101114 Procavia capensis 58.68 2.00e-91 329.00
IUUC-Pva-102268 Pteropus vampyrus 71.19 8.00e-132 463.00
IUUC-Pgr-103461 Puccinia graminis 43.18 1.00e-04 41.60
IUUC-Ptt-103780 Puccinia triticina 42.86 2.00e-04 40.80
IUUC-Rno-105274 Rattus norvegicus 66.31 0.00e+00 669.00
IUUC-Sce-106220 Saccharomyces cerevisiae 37.74 1.00e-04 41.20
IUUC-Sha-107258 Sarcophilus harrisii 67.74 4.00e-170 590.00
IUUC-Sit-110285 Setaria italica 29.03 6.00e-03 35.40
IUUC-Stu-112846 Solanum tuberosum 29.82 3.00e-03 37.00
IUUC-Ssc-115393 Sus scrofa 72.84 0.00e+00 728.00
IUUC-Tgu-116622 Taeniopygia guttata 63.41 0.00e+00 680.00
IUUC-Tru-118647 Takifugu rubripes 66.18 0.00e+00 717.00
IUUC-Tni-120516 Tetraodon nigroviridis 63.84 0.00e+00 640.00
IUUC-Tae-122758 Triticum aestivum 31.25 2.00e-04 40.40
IUUC-Tur-126040 Triticum urartu 31.25 1.00e-04 39.70
IUUC-Tme-127118 Tuber melanosporum 35.71 4.00e-05 42.40
IUUC-Tbe-127269 Tupaia belangeri 64.40 2.00e-161 561.00
IUUC-Ttr-129258 Tursiops truncatus 66.59 2.00e-172 598.00
IUUC-Vpa-130056 Vicugna pacos 48.51 5.00e-30 124.00
IUUC-Vvi-131081 Vitis vinifera 37.50 2.00e-04 41.20
IUUC-Xma-134200 Xiphophorus maculatus 62.99 5.00e-178 617.00
IUUC-Yli-134540 Yarrowia lipolytica 33.96 7.00e-04 39.30
Created Date 25-Jun-2017

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