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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Rno-105312
UUCD1 version UUC-RaN-00111
Ensembl Protein ID ENSRNOP00000048511.5
UniProt Accession A0A096UWG1; A0A096UWG1_RAT
Genbank Protein ID EDM09451.1
Protein Name Ring finger and WD repeat domain 2; Similar to constitutive photomorphogenic protein 1, isoform CRA_b
Genbank Nucleotide ID AABR07021533
Gene Name Rfwd2; RGD1304773; rCG_46108
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSRNOG00000042492.4 ENSRNOT00000040505.6 ENSRNOP00000048511.5
ENSRNOG00000042492.4 ENSRNOT00000076908.2 ENSRNOP00000068019.1
ENSRNOG00000042492.4 ENSRNOT00000076581.1 ENSRNOP00000068073.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.10e-23 81.8 472 501
E3 activity/RING/RING 2.70e-06 28.2 138 176
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 3    tdsvtclaf..sd.tllvsGsdDgtikvWD 29
           +++++c+++     +ll+s+ + gt+ +WD
   Q: 472  NSKISCISWssYHkNLLASSDYEGTVILWD 501
           689******9622599************** PP
   

   E3 activity/RING/RING
   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iC++++++  + + CgH f+ +C+++          + rCP C+
   Q: 138  CPICFDMIEE-AYMTKCGHSFCYKCIHQS------LEDNNRCPKCN 176
           ********99.888***********9555......999999****6 PP
   
Organism Rattus norvegicus
Protein Sequence
(Fasta)
MSGSRQAGSG SAGTSPGSSA ASSVTSASSS LSSSPSPPSV AASAATLVSG GVAPAAGSGG 60
LGGPGRPVLV AAAVSGSASA GGAVSAGLSR LSCAARPSAG VGGSSSSLGS SSRKRPLIAP 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Rno-105312|E3,WD_repeat;E3,RING|Rattus norvegicus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGCAGTTGCT TTTTGAGCGT TCCCGGTTCT CTAGACCAGA TCCCCGTCCC TTCCTCTTCT 60
ACTCTTTGGC TCCATGAAAA CGGCCATCCT TCTACTACGT CAGGAACGAA ACCAACTTTC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Rno-105312|E3,WD_repeat;E3,RING|Rattus norvegicus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat
Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
PS00518--ZF_RING_1
PS50089--ZF_RING_2
Pfam

PF00400--WD40
SMART

SM00184--RING
SM00320--WD40
Gene Ontology

GO:0000139--C:Golgi membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0010212--P:response to ionizing radiation
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000885 Aegilops tauschii 39.94 5.00e-126 444.00
IUUC-Aml-001265 Ailuropoda melanoleuca 99.35 0.00e+00 1246.00
IUUC-Atr-002460 Amborella trichopoda 38.52 1.00e-124 440.00
IUUC-Apl-003796 Anas platyrhynchos 97.93 0.00e+00 1154.00
IUUC-Aca-005078 Anolis carolinensis 97.42 0.00e+00 1211.00
IUUC-Aly-006014 Arabidopsis lyrata 40.03 3.00e-130 458.00
IUUC-Ath-007636 Arabidopsis thaliana 39.94 4.00e-130 458.00
IUUC-Ame-011176 Astyanax mexicanus 74.73 1.00e-69 257.00
IUUC-Bta-012595 Bos taurus 98.91 0.00e+00 1261.00
IUUC-Bdi-014152 Brachypodium distachyon 39.08 1.00e-128 453.00
IUUC-Bol-016380 Brassica oleracea 40.21 1.00e-131 463.00
IUUC-Bra-017690 Brassica rapa 39.24 6.00e-126 444.00
IUUC-Cja-018926 Callithrix jacchus 98.76 0.00e+00 1256.00
IUUC-Cfa-021088 Canis familiaris 98.60 0.00e+00 1260.00
IUUC-Cpo-022442 Cavia porcellus 97.79 0.00e+00 1222.00
IUUC-Cre-022579 Chlamydomonas reinhardtii 33.45 3.00e-33 135.00
IUUC-Csa-024119 Chlorocebus sabaeus 97.08 0.00e+00 1246.00
IUUC-Cho-024883 Choloepus hoffmanni 66.23 3.00e-105 376.00
IUUC-Cin-025375 Ciona intestinalis 55.96 0.00e+00 683.00
IUUC-Cme-027350 Cyanidioschyzon merolae 41.62 1.00e-79 291.00
IUUC-Dre-028453 Danio rerio 87.56 0.00e+00 1082.00
IUUC-Dno-029887 Dasypus novemcinctus 98.28 0.00e+00 1247.00
IUUC-Dor-031110 Dipodomys ordii 89.73 0.00e+00 873.00
IUUC-Ete-033016 Echinops telfairi 84.50 0.00e+00 1043.00
IUUC-Eca-034403 Equus caballus 98.96 0.00e+00 1157.00
IUUC-Eeu-034690 Erinaceus europaeus 82.02 0.00e+00 959.00
IUUC-Fca-036475 Felis catus 98.62 0.00e+00 1161.00
IUUC-Fal-037189 Ficedula albicollis 98.49 0.00e+00 1190.00
IUUC-Gmo-039245 Gadus morhua 86.95 0.00e+00 1058.00
IUUC-Gga-040806 Gallus gallus 98.23 0.00e+00 1238.00
IUUC-Gac-042177 Gasterosteus aculeatus 88.32 0.00e+00 1103.00
IUUC-Gma-044187 Glycine max 40.58 4.00e-127 448.00
IUUC-Ggo-044430 Gorilla gorilla 98.09 0.00e+00 931.00
IUUC-Hsa-045853 Homo sapiens 98.76 0.00e+00 1256.00
IUUC-Hvu-047750 Hordeum vulgare 38.79 7.00e-95 342.00
IUUC-Itr-048238 Ictidomys tridecemlineatus 100.00 6.00e-145 506.00
IUUC-Lch-050420 Latimeria chalumnae 92.20 0.00e+00 1153.00
IUUC-Lpe-051219 Leersia perrieri 38.82 2.00e-124 439.00
IUUC-Loc-052728 Lepisosteus oculatus 91.13 0.00e+00 1105.00
IUUC-Laf-053775 Loxodonta africana 97.97 0.00e+00 1255.00
IUUC-Meu-056595 Macropus eugenii 77.93 9.00e-178 617.00
IUUC-Mtr-058555 Medicago truncatula 40.80 6.00e-134 471.00
IUUC-Mga-059646 Meleagris gallopavo 97.60 0.00e+00 1152.00
IUUC-Mmr-060990 Microcebus murinus 98.75 0.00e+00 1255.00
IUUC-Mdo-062287 Monodelphis domestica 98.55 0.00e+00 1246.00
IUUC-Mmu-064097 Mus musculus 99.53 0.00e+00 1268.00
IUUC-Mac-065240 Musa acuminata 41.22 3.00e-136 479.00
IUUC-Mpu-066612 Mustela putorius furo 98.63 0.00e+00 1165.00
IUUC-Mlu-067967 Myotis lucifugus 96.82 0.00e+00 1164.00
IUUC-Nle-069543 Nomascus leucogenys 98.91 0.00e+00 1261.00
IUUC-Opr-070366 Ochotona princeps 84.11 0.00e+00 717.00
IUUC-Ont-071522 Oreochromis niloticus 88.00 0.00e+00 1092.00
IUUC-Oan-073409 Ornithorhynchus anatinus 98.45 0.00e+00 1158.00
IUUC-Ocu-073756 Oryctolagus cuniculus 98.88 0.00e+00 1230.00
IUUC-Oba-075149 Oryza barthii 39.60 8.00e-128 451.00
IUUC-Obr-076563 Oryza brachyantha 39.78 3.00e-128 452.00
IUUC-Ogl-077701 Oryza glaberrima 39.32 1.00e-128 453.00
IUUC-Ogu-078383 Oryza glumaepatula 39.32 1.00e-128 453.00
IUUC-Oin-079965 Oryza indica 37.41 9.00e-115 407.00
IUUC-Olo-080639 Oryza longistaminata 39.16 3.00e-126 445.00
IUUC-Ome-081821 Oryza meridionalis 38.86 3.00e-116 412.00
IUUC-Oni-082622 Oryza nivara 39.32 1.00e-128 453.00
IUUC-Opu-083295 Oryza punctata 39.02 2.00e-128 452.00
IUUC-Oru-084661 Oryza rufipogon 39.32 1.00e-128 453.00
IUUC-Osa-085766 Oryza sativa 39.32 1.00e-128 453.00
IUUC-Ola-086727 Oryzias latipes 87.82 0.00e+00 1109.00
IUUC-Olu-087702 Ostreococcus lucimarinus 42.99 3.00e-69 254.00
IUUC-Oga-088215 Otolemur garnettii 96.89 0.00e+00 1233.00
IUUC-Oar-089880 Ovis aries 98.89 0.00e+00 1230.00
IUUC-Ptr-090597 Pan troglodytes 98.76 0.00e+00 1256.00
IUUC-Pan-091987 Papio anubis 98.91 0.00e+00 1261.00
IUUC-Psi-094033 Pelodiscus sinensis 97.97 0.00e+00 1167.00
IUUC-Pma-094587 Petromyzon marinus 70.56 0.00e+00 803.00
IUUC-Ppa-095256 Physcomitrella patens 39.88 3.00e-134 472.00
IUUC-Pfo-097388 Poecilia formosa 87.00 0.00e+00 1071.00
IUUC-Pab-098029 Pongo abelii 98.76 0.00e+00 1256.00
IUUC-Pop-099319 Populus trichocarpa 38.92 5.00e-131 461.00
IUUC-Pca-100846 Procavia capensis 90.48 0.00e+00 1142.00
IUUC-Ppe-101250 Prunus persica 38.89 5.00e-121 428.00
IUUC-Pva-102407 Pteropus vampyrus 98.45 0.00e+00 1249.00
IUUC-Sha-106514 Sarcophilus harrisii 97.88 0.00e+00 777.00
IUUC-Smo-109418 Selaginella moellendorffii 40.03 4.00e-131 462.00
IUUC-Sit-110248 Setaria italica 38.77 7.00e-128 451.00
IUUC-Sly-110964 Solanum lycopersicum 40.58 2.00e-131 462.00
IUUC-Stu-112882 Solanum tuberosum 40.80 1.00e-132 467.00
IUUC-Sar-113230 Sorex araneus 71.86 0.00e+00 798.00
IUUC-Sbi-113962 Sorghum bicolor 36.75 3.00e-123 436.00
IUUC-Ssc-115987 Sus scrofa 98.52 0.00e+00 626.00
IUUC-Tgu-116471 Taeniopygia guttata 97.89 0.00e+00 1231.00
IUUC-Tru-118231 Takifugu rubripes 87.68 0.00e+00 1055.00
IUUC-Tsy-119415 Tarsius syrichta 98.66 0.00e+00 1170.00
IUUC-Tni-120893 Tetraodon nigroviridis 87.84 0.00e+00 1063.00
IUUC-Tca-121703 Theobroma cacao 41.05 2.00e-129 456.00
IUUC-Tae-125317 Triticum aestivum 40.92 4.00e-134 471.00
IUUC-Tur-126557 Triticum urartu 40.62 4.00e-129 455.00
IUUC-Tbe-127253 Tupaia belangeri 71.32 0.00e+00 848.00
IUUC-Ttr-129100 Tursiops truncatus 97.48 0.00e+00 1144.00
IUUC-Vpa-130613 Vicugna pacos 92.61 0.00e+00 1096.00
IUUC-Vvi-130880 Vitis vinifera 40.97 3.00e-123 435.00
IUUC-Xtr-132033 Xenopus tropicalis 95.33 0.00e+00 1234.00
IUUC-Xma-133421 Xiphophorus maculatus 86.84 0.00e+00 1069.00
Created Date 25-Jun-2017

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