iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

   S: 1    gHtdsvtclaf.....sd.tllvsGsdDgtikvWDlrt 32
           gHtd ++++++     s+  l+++++ Dg+++++ + t
   Q: 213  GHTDLIRDICWapsmgSSyYLIATACKDGNVRIFKVET 250
           8************99977788*************9876 PP

Organism

Schizosaccharomyces pombe

Functional Description
(View)

Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope.

Protein Sequence
(Fasta)

MDDISATTIQ TNHQDLVNDV TYDFYGRRMV SCSADQRVKV YDFNDDTETW AITSEWRAGD 60
ASLMRVAWAH PSFGQVLAVC SLDRGVRIYE EQKKNFESKT WVEVAKLMDA RSAVLDISFC 120

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Nucleotide Sequence
(Fasta)

CCACTAACAA CTAAATAATT TAGTAGTCCG GAAGACTATT TGTATAGTAC TTGAAACTTT 60
CATTTCATTT TTTAAACGTC AATGAACATA TTAGATTATT ATCGTTTTGG CTTACCAAAT 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0509--mRNA transport
KW-0906--Nuclear pore complex
KW-0539--Nucleus
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0811--Translocation
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0034399--C:nuclear periphery
GO:0005643--C:nuclear pore
GO:0031080--C:nuclear pore outer ring
GO:0005634--C:nucleus
GO:0035859--C:Seh1-associated complex
GO:0051028--P:mRNA transport
GO:0006407--P:rRNA export from nucleus

KEGG

spo:SPAC15F9.02

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001926	Ailuropoda melanoleuca	37.76	8.00e-61	225.00
IUUC-Apl-003654	Anas platyrhynchos	36.33	8.00e-50	188.00
IUUC-Aca-004378	Anolis carolinensis	37.30	1.00e-50	191.00
IUUC-Ago-007816	Ashbya gossypii	40.37	7.00e-79	285.00
IUUC-Acl-008248	Aspergillus clavatus	27.25	7.00e-34	135.00
IUUC-Afl-008667	Aspergillus flavus	27.15	4.00e-32	130.00
IUUC-Afu-008961	Aspergillus fumigatus	26.59	3.00e-33	134.00
IUUC-Ani-009218	Aspergillus nidulans	30.77	2.00e-30	124.00
IUUC-Ame-011945	Astyanax mexicanus	38.55	2.00e-62	231.00
IUUC-Bta-013306	Bos taurus	38.46	6.00e-62	228.00
IUUC-Cel-018235	Caenorhabditis elegans	31.16	7.00e-40	155.00
IUUC-Cja-018849	Callithrix jacchus	38.46	9.00e-61	225.00
IUUC-Cfa-020841	Canis familiaris	38.11	7.00e-59	221.00
IUUC-Cpo-021379	Cavia porcellus	37.87	2.00e-60	224.00
IUUC-Csa-023900	Chlorocebus sabaeus	38.17	2.00e-61	227.00
IUUC-Cho-024660	Choloepus hoffmanni	36.33	4.00e-48	182.00
IUUC-Cin-025471	Ciona intestinalis	32.75	2.00e-47	180.00
IUUC-Csv-026242	Ciona savignyi	36.29	8.00e-44	168.00
IUUC-Dre-028068	Danio rerio	39.88	1.00e-65	241.00
IUUC-Dno-029981	Dasypus novemcinctus	37.64	6.00e-64	236.00
IUUC-Dse-031420	Dothistroma septosporum	27.40	1.00e-32	131.00
IUUC-Dme-031763	Drosophila melanogaster	34.71	3.00e-55	206.00
IUUC-Ete-032243	Echinops telfairi	44.19	6.00e-17	79.30
IUUC-Eca-033425	Equus caballus	37.07	7.00e-48	182.00
IUUC-Eeu-035119	Erinaceus europaeus	44.66	3.00e-20	90.50
IUUC-Fca-036520	Felis catus	37.79	6.00e-62	229.00
IUUC-Fal-037234	Ficedula albicollis	36.42	5.00e-50	192.00
IUUC-Gmo-039013	Gadus morhua	38.08	2.00e-62	230.00
IUUC-Gga-041059	Gallus gallus	38.26	2.00e-63	234.00
IUUC-Gac-041337	Gasterosteus aculeatus	38.08	3.00e-64	236.00
IUUC-Ggo-044944	Gorilla gorilla	37.79	7.00e-62	229.00
IUUC-Hsa-046038	Homo sapiens	37.79	7.00e-62	229.00
IUUC-Itr-048858	Ictidomys tridecemlineatus	37.07	6.00e-48	182.00
IUUC-Kpa-049201	Komagataella pastoris	40.85	3.00e-76	276.00
IUUC-Lch-050466	Latimeria chalumnae	34.10	3.00e-56	210.00
IUUC-Loc-052773	Lepisosteus oculatus	34.96	5.00e-59	219.00
IUUC-Lma-053000	Leptosphaeria maculans	25.28	1.00e-32	132.00
IUUC-Laf-053409	Loxodonta africana	38.46	9.00e-62	228.00
IUUC-Mla-058820	Melampsora laricipopulina	26.00	4.00e-30	123.00
IUUC-Mga-059348	Meleagris gallopavo	36.66	4.00e-50	189.00
IUUC-Mmr-060977	Microcebus murinus	38.06	7.00e-41	158.00
IUUC-Mdo-061806	Monodelphis domestica	37.97	1.00e-62	231.00
IUUC-Mmu-064328	Mus musculus	37.86	3.00e-64	236.00
IUUC-Mpu-066873	Mustela putorius furo	38.17	8.00e-61	225.00
IUUC-Mlu-067563	Myotis lucifugus	38.08	9.00e-61	225.00
IUUC-Nfi-068299	Neosartorya fischeri	27.86	1.00e-33	135.00
IUUC-Nle-068977	Nomascus leucogenys	36.76	8.00e-53	198.00
IUUC-Ont-072644	Oreochromis niloticus	38.37	1.00e-63	234.00
IUUC-Oan-073098	Ornithorhynchus anatinus	35.90	8.00e-49	185.00
IUUC-Ocu-073911	Oryctolagus cuniculus	37.79	8.00e-62	228.00
IUUC-Ola-087096	Oryzias latipes	39.53	4.00e-64	236.00
IUUC-Oga-088798	Otolemur garnettii	37.79	5.00e-62	229.00
IUUC-Oar-090298	Ovis aries	36.27	9.00e-48	185.00
IUUC-Ptr-091074	Pan troglodytes	37.79	4.00e-62	229.00
IUUC-Pan-092013	Papio anubis	38.22	9.00e-43	164.00
IUUC-Psi-093508	Pelodiscus sinensis	37.01	9.00e-50	188.00
IUUC-Pma-094288	Petromyzon marinus	40.44	1.00e-37	147.00
IUUC-Pno-094777	Phaeosphaeria nodorum	28.79	2.00e-29	121.00
IUUC-Pfo-096384	Poecilia formosa	38.37	3.00e-64	236.00
IUUC-Pab-098629	Pongo abelii	37.79	4.00e-62	229.00
IUUC-Pva-102861	Pteropus vampyrus	38.46	1.00e-61	228.00
IUUC-Pte-104375	Pyrenophora teres	28.69	6.00e-36	143.00
IUUC-Pyt-104586	Pyrenophora triticirepentis	28.02	3.00e-36	144.00
IUUC-Rno-104895	Rattus norvegicus	36.42	8.00e-50	191.00
IUUC-Sce-106420	Saccharomyces cerevisiae	40.99	8.00e-84	301.00
IUUC-Sha-106829	Sarcophilus harrisii	34.87	6.00e-51	192.00
IUUC-Sja-107923	Schizosaccharomyces japonicus	56.05	7.00e-119	417.00
IUUC-Sar-113279	Sorex araneus	36.18	1.00e-47	181.00
IUUC-Ssc-115589	Sus scrofa	35.67	9.00e-48	181.00
IUUC-Tgu-117523	Taeniopygia guttata	37.97	4.00e-63	233.00
IUUC-Tru-117985	Takifugu rubripes	34.36	1.00e-48	187.00
IUUC-Tsy-118913	Tarsius syrichta	35.99	3.00e-42	163.00
IUUC-Tni-120670	Tetraodon nigroviridis	38.95	3.00e-64	236.00
IUUC-Tvi-122555	Trichoderma virens	23.58	2.00e-25	107.00
IUUC-Tme-126885	Tuber melanosporum	41.30	9.00e-79	284.00
IUUC-Tbe-127344	Tupaia belangeri	30.03	1.00e-40	158.00
IUUC-Ttr-128347	Tursiops truncatus	36.73	1.00e-47	181.00
IUUC-Vpa-130656	Vicugna pacos	36.39	5.00e-47	179.00
IUUC-Xtr-132736	Xenopus tropicalis	38.66	5.00e-63	232.00
IUUC-Xma-133678	Xiphophorus maculatus	39.24	4.00e-65	239.00
IUUC-Yli-134659	Yarrowia lipolytica	44.41	3.00e-87	313.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence