iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062694

UUCD1 version

UUC-MoD-00924

Ensembl Protein ID

ENSMODP00000001649.2

UniProt Accession

F7FVZ4; F7FVZ4_MONDO

Protein Name

Uncharacterized protein

Gene Name

WDR77

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000001364.2	ENSMODT00000001683.2	ENSMODP00000001649.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-17	63.3	127	162

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtcla.f.sdtllvsGsdDgtikvWDlrtgvl 35
           H d vt+++ + ++t  vsGs D  ik+WDl + ++
   Q: 127  HDDIVTSVSaLlPGTQAVSGSKDFCIKLWDLGQEKV 162
           9999****647999****************977665 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MRQEESSPSI SSLPRPVPEW NLPPNAPACM ERQLEAARYR SDGSLLLGAS SLSGRSWAGS 60
LWLFKDPLAA PNEGFCSAGV QTEAGLSDLT WVGDRGILVA SDSGAVELWE LDDSETLIVS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCGGCAGG AGGAGTCGTC GCCGTCAATA TCGTCCCTTC CTCGTCCCGT TCCAGAATGG 60
AACCTACCGC CCAACGCGCC GGCATGTATG GAGCGGCAGC TGGAGGCAGC GCGCTACCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0034709--C:methylosome
GO:0005654--C:nucleoplasm
GO:0030374--F:ligand-dependent nuclear receptor transcription coactivator activity
GO:0008327--F:methyl-CpG binding
GO:0060770--P:negative regulation of epithelial cell proliferation involved in prostate gland development
GO:0008284--P:positive regulation of cell proliferation
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0060528--P:secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002192	Ailuropoda melanoleuca	74.12	6.00e-136	476.00
IUUC-Apl-003921	Anas platyrhynchos	60.80	3.00e-57	214.00
IUUC-Aca-004870	Anolis carolinensis	63.25	6.00e-106	377.00
IUUC-Ame-011872	Astyanax mexicanus	47.62	1.00e-36	145.00
IUUC-Bta-013325	Bos taurus	72.62	8.00e-137	479.00
IUUC-Cja-019059	Callithrix jacchus	74.05	7.00e-139	486.00
IUUC-Cfa-021036	Canis familiaris	73.33	4.00e-120	424.00
IUUC-Cpo-022369	Cavia porcellus	73.53	1.00e-137	482.00
IUUC-Csa-023585	Chlorocebus sabaeus	73.47	7.00e-139	486.00
IUUC-Cho-024470	Choloepus hoffmanni	66.24	3.00e-85	307.00
IUUC-Dno-029867	Dasypus novemcinctus	73.47	1.00e-137	482.00
IUUC-Dor-030834	Dipodomys ordii	62.08	9.00e-77	280.00
IUUC-Ete-032245	Echinops telfairi	68.73	5.00e-110	390.00
IUUC-Eca-033360	Equus caballus	74.05	4.00e-135	474.00
IUUC-Eeu-035353	Erinaceus europaeus	72.38	1.00e-136	479.00
IUUC-Fca-036277	Felis catus	74.04	4.00e-137	480.00
IUUC-Fal-037383	Ficedula albicollis	64.11	3.00e-90	324.00
IUUC-Gmo-038575	Gadus morhua	54.18	7.00e-92	330.00
IUUC-Gga-040658	Gallus gallus	65.71	1.00e-115	409.00
IUUC-Gac-041463	Gasterosteus aculeatus	52.16	1.00e-81	296.00
IUUC-Ggo-045120	Gorilla gorilla	73.47	3.00e-138	484.00
IUUC-Hsa-046247	Homo sapiens	73.76	5.00e-139	486.00
IUUC-Itr-048292	Ictidomys tridecemlineatus	75.00	3.00e-138	484.00
IUUC-Lch-049741	Latimeria chalumnae	63.01	2.00e-107	382.00
IUUC-Loc-052695	Lepisosteus oculatus	57.68	1.00e-98	353.00
IUUC-Laf-054535	Loxodonta africana	72.75	7.00e-137	479.00
IUUC-Mcc-054699	Macaca mulatta	73.47	7.00e-139	486.00
IUUC-Meu-056053	Macropus eugenii	79.24	7.00e-144	503.00
IUUC-Mga-059672	Meleagris gallopavo	60.11	2.00e-60	224.00
IUUC-Mmr-060963	Microcebus murinus	74.05	3.00e-138	484.00
IUUC-Mmu-064031	Mus musculus	72.01	2.00e-134	471.00
IUUC-Mpu-066408	Mustela putorius furo	74.04	7.00e-137	479.00
IUUC-Mlu-068184	Myotis lucifugus	72.38	9.00e-135	473.00
IUUC-Nle-069251	Nomascus leucogenys	74.34	2.00e-139	488.00
IUUC-Opr-071156	Ochotona princeps	67.93	3.00e-127	447.00
IUUC-Ont-072683	Oreochromis niloticus	55.21	8.00e-90	323.00
IUUC-Oan-073042	Ornithorhynchus anatinus	69.44	4.00e-110	390.00
IUUC-Ocu-074843	Oryctolagus cuniculus	72.97	1.00e-135	476.00
IUUC-Ola-086929	Oryzias latipes	50.46	1.00e-82	299.00
IUUC-Oga-088237	Otolemur garnettii	73.18	8.00e-139	486.00
IUUC-Oar-089312	Ovis aries	74.21	4.00e-128	450.00
IUUC-Ptr-091625	Pan troglodytes	74.05	2.00e-139	488.00
IUUC-Pan-091902	Papio anubis	75.00	1.00e-134	473.00
IUUC-Psi-094035	Pelodiscus sinensis	63.82	3.00e-110	391.00
IUUC-Pma-094565	Petromyzon marinus	57.54	7.00e-49	186.00
IUUC-Pfo-097070	Poecilia formosa	52.05	6.00e-88	317.00
IUUC-Pab-098007	Pongo abelii	73.47	2.00e-138	485.00
IUUC-Pca-100513	Procavia capensis	58.67	2.00e-74	272.00
IUUC-Pva-102821	Pteropus vampyrus	67.45	3.00e-121	428.00
IUUC-Rno-105836	Rattus norvegicus	73.62	3.00e-139	488.00
IUUC-Sha-106847	Sarcophilus harrisii	71.43	8.00e-94	336.00
IUUC-Sar-113451	Sorex araneus	70.71	2.00e-131	462.00
IUUC-Ssc-115978	Sus scrofa	74.78	7.00e-137	479.00
IUUC-Tgu-116745	Taeniopygia guttata	62.77	3.00e-83	300.00
IUUC-Tru-117945	Takifugu rubripes	52.01	3.00e-78	285.00
IUUC-Tsy-119059	Tarsius syrichta	64.44	7.00e-63	232.00
IUUC-Tni-120414	Tetraodon nigroviridis	52.52	9.00e-87	313.00
IUUC-Tbe-127559	Tupaia belangeri	73.76	2.00e-138	485.00
IUUC-Ttr-128505	Tursiops truncatus	71.43	4.00e-130	457.00
IUUC-Vpa-130350	Vicugna pacos	78.49	3.00e-84	303.00
IUUC-Xtr-132939	Xenopus tropicalis	58.49	1.00e-103	369.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence