iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-098007

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Methylosome protein 50

Genbank Nucleotide ID

ABGA01279990

Gene Name

WDR77

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000001033.2	ENSPPYT00000001242.2	ENSPPYP00000001202.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.60e-17	61.5	124	160

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           H d v+ ++  s+ t  vsGs D  ikvWDl ++v+l
   Q: 124  HDDIVSTVSVlSSgTQAVSGSKDICIKVWDLAQQVVL 160
           89999999977555*****************999876 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MRKETPPPLV PPAAREWNLP PNAPACMERQ LEAARYRSDG ALLLGASSLS GRCWAGSLWL 60
FKDPCAAPNE GFCSAGVQTE AGVADLTWVG ERGILVASDS GAVELWELDE NETLIVSKFC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCGGAAGG AAACCCCACC CCCTCTAGTG CCCCCGGCGG CCCGGGAGTG GAATCTTCCC 60
CCTAATGCGC CCGCCTGCAT GGAACGGCAG TTGGAGGCTG CGCGGTACCG GTCCGGTGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0034709--C:methylosome
GO:0005654--C:nucleoplasm
GO:0030374--F:ligand-dependent nuclear receptor transcription coactivator activity
GO:0008327--F:methyl-CpG binding
GO:0060770--P:negative regulation of epithelial cell proliferation involved in prostate gland development
GO:0008284--P:positive regulation of cell proliferation
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0060528--P:secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002192	Ailuropoda melanoleuca	91.55	4.00e-179	620.00
IUUC-Apl-003921	Anas platyrhynchos	62.63	5.00e-66	243.00
IUUC-Aca-004870	Anolis carolinensis	70.61	1.00e-119	422.00
IUUC-Ame-011872	Astyanax mexicanus	46.67	9.00e-38	149.00
IUUC-Bta-013325	Bos taurus	92.69	0.00e+00	631.00
IUUC-Cja-019059	Callithrix jacchus	97.66	0.00e+00	653.00
IUUC-Cfa-021036	Canis familiaris	91.41	9.00e-158	549.00
IUUC-Cpo-022369	Cavia porcellus	90.64	2.00e-178	618.00
IUUC-Csa-023585	Chlorocebus sabaeus	98.83	0.00e+00	662.00
IUUC-Cho-024470	Choloepus hoffmanni	83.82	9.00e-116	409.00
IUUC-Dno-029867	Dasypus novemcinctus	89.47	1.00e-178	618.00
IUUC-Dor-030834	Dipodomys ordii	64.72	6.00e-115	407.00
IUUC-Ete-032245	Echinops telfairi	83.16	3.00e-140	490.00
IUUC-Eca-033360	Equus caballus	92.11	2.00e-174	604.00
IUUC-Eeu-035353	Erinaceus europaeus	90.35	7.00e-178	615.00
IUUC-Fca-036277	Felis catus	93.27	0.00e+00	632.00
IUUC-Fal-037383	Ficedula albicollis	67.05	2.00e-102	364.00
IUUC-Gmo-038575	Gadus morhua	54.65	3.00e-100	357.00
IUUC-Gga-040658	Gallus gallus	69.33	1.00e-128	452.00
IUUC-Gac-041463	Gasterosteus aculeatus	52.04	7.00e-85	306.00
IUUC-Ggo-045120	Gorilla gorilla	99.12	0.00e+00	664.00
IUUC-Hsa-046247	Homo sapiens	99.42	0.00e+00	666.00
IUUC-Itr-048292	Ictidomys tridecemlineatus	94.74	0.00e+00	626.00
IUUC-Lch-049741	Latimeria chalumnae	65.82	5.00e-113	400.00
IUUC-Loc-052695	Lepisosteus oculatus	59.58	6.00e-107	380.00
IUUC-Laf-054535	Loxodonta africana	89.08	4.00e-176	610.00
IUUC-Mcc-054699	Macaca mulatta	98.83	0.00e+00	662.00
IUUC-Meu-056053	Macropus eugenii	76.09	1.00e-138	485.00
IUUC-Mga-059672	Meleagris gallopavo	64.43	4.00e-71	260.00
IUUC-Mmr-060963	Microcebus murinus	93.86	0.00e+00	640.00
IUUC-Mdo-062694	Monodelphis domestica	73.47	3.00e-132	464.00
IUUC-Mmu-064031	Mus musculus	89.77	5.00e-177	613.00
IUUC-Mpu-066408	Mustela putorius furo	92.69	0.00e+00	630.00
IUUC-Mlu-068184	Myotis lucifugus	90.09	4.00e-176	610.00
IUUC-Nle-069251	Nomascus leucogenys	98.54	0.00e+00	661.00
IUUC-Opr-071156	Ochotona princeps	85.09	3.00e-165	573.00
IUUC-Ont-072683	Oreochromis niloticus	57.32	2.00e-97	348.00
IUUC-Oan-073042	Ornithorhynchus anatinus	75.87	6.00e-127	446.00
IUUC-Ocu-074843	Oryctolagus cuniculus	93.59	3.00e-177	613.00
IUUC-Ola-086929	Oryzias latipes	53.54	4.00e-89	321.00
IUUC-Oga-088237	Otolemur garnettii	92.69	0.00e+00	629.00
IUUC-Oar-089312	Ovis aries	92.41	1.00e-166	578.00
IUUC-Ptr-091625	Pan troglodytes	99.42	0.00e+00	666.00
IUUC-Pan-091902	Papio anubis	93.90	2.00e-180	624.00
IUUC-Psi-094035	Pelodiscus sinensis	71.53	3.00e-126	444.00
IUUC-Pma-094565	Petromyzon marinus	63.48	5.00e-57	213.00
IUUC-Pfo-097070	Poecilia formosa	54.49	2.00e-92	332.00
IUUC-Pca-100513	Procavia capensis	74.44	2.00e-104	371.00
IUUC-Pva-102821	Pteropus vampyrus	87.13	2.00e-166	578.00
IUUC-Rno-105836	Rattus norvegicus	88.79	5.00e-178	616.00
IUUC-Sha-106847	Sarcophilus harrisii	69.80	3.00e-88	317.00
IUUC-Sar-113451	Sorex araneus	85.42	6.00e-169	586.00
IUUC-Ssc-115978	Sus scrofa	91.52	1.00e-174	605.00
IUUC-Tgu-116745	Taeniopygia guttata	69.30	4.00e-95	340.00
IUUC-Tru-117945	Takifugu rubripes	52.80	2.00e-81	295.00
IUUC-Tsy-119059	Tarsius syrichta	89.27	3.00e-91	326.00
IUUC-Tni-120414	Tetraodon nigroviridis	54.60	2.00e-94	338.00
IUUC-Tbe-127559	Tupaia belangeri	95.32	0.00e+00	645.00
IUUC-Ttr-128505	Tursiops truncatus	90.35	2.00e-175	607.00
IUUC-Vpa-130350	Vicugna pacos	94.51	3.00e-101	360.00
IUUC-Xtr-132939	Xenopus tropicalis	62.15	8.00e-114	403.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence